姓名：陈晨 性别：男 职称：研究员、副教授 招生院所：地坛医院 招生类型：科学学位(硕) 招生专业：免疫学(硕) 研究方向名称：病原与免疫学 电子信箱：chenchen_bj2008@163.com


社会任职
个人简历
1. 199809-200207:北京大学生物系 学习
2. 199909-200207:北京大学软件工程学院 学习
3. 200209-200909:华大基因 项目负责人
4. 200909-201501:中国疾病预防控制中心传染病所 副主任
5. 201502-:首都医科大学附属北京地坛医院 任职
重要学术论文
1. Jing Yuan#,*, Chen Chen#, Jinghua Cui#, Jing Lu#, Chao Yan#, Xiao Wei, Xiangna Zhao, NanNan Li, Shaoli Li, Guanhua Xue, Weiwei Cheng, Boxing Li, Huan Li, Weishi Lin, Changyu Tian, Jiangtao Zhao, Juqiang Han, Daizhi An, Qiong Zhang, et al., Hui Zeng, Sun Ying, JianXin Wu, Ruifu Yang*, Di Liu*. .Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae. Cell Metabolism. 2019,30(4):675-688.SCI
2. Li J#, Du P#, Ye AY, Zhang Y, Song C, Zeng H*, Chen C*..GPA: A Microbial Genetic Polymorphisms Assignments Tool in Metagenomic Analysis by Bayesian Estimation. Genomics Proteomics Bioinformatics.. Genomics Proteomics Bioinformatics. . 2019,17(1):106-117.SCI
3. C Chen#*, D Jiang#, M Ni#, J Li#, Z Chen, J Liu, H Ye, G Wong, W Li, Y Zhang, B Wang, Y Bi, D Chen, P Zhang, X Zhao, Y Kong, W Shi, P Du, G Xiao, J Ma, G F. Gao, J Cui, F Zhang, W Liu, X Bo, A Li*, H Zeng*, D Liu*.Phylogenomic analysis unravels evolution of yellow fever virus within hosts. PLoS Negl Trop Dis. 2018,12(9):e**.SCI
4. Pengcheng Du, Yuanyuan Zhang，Chen Chen*.Emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae. The Lancet infectious diseases. 2017,18（1）:23-24.SCI
5. Jing Wang#*, Youjun Feng#, Changjun Wang, Swaminath Srinivas, Chen Chen, Hui Liao, Elaine He, Shibo Jiang, Jiaqi Tang*.Pathogenic Streptococcus strains employ novel escape strategy to inhibit bacteriostatic effect mediated by mammalian peptidoglycan recognition protein: Pathogenic Streptococcus escapes PGRP killing. Cellular Microbiology. 2017,19（7）:e12724.SCI
6. Wen Zhang*, Ying Cheng*, Pengcheng Du*, Yuanyuan Zhang, Hongbing Jia, Xianping Li, Jing Wang, Na Han, Yujun Qiang, Chen Chen#, Jinxing Lu#.Genomic study of the Type IVC secretion system in Clostridium difficile: Understanding C. difficile evolution via horizontal gene transfer. Genome. 2017,1（1）:8-16.SCI
7. Hao Q#, Du P#, Zhang W, Hou X, Zhang L, Zhang Y, Liu H, Liu W, Chen C*, Wan K.Genomic Characteristics of Chinese Borrelia burgdorferi Isolates. Plos One. 2016,11(4):e**.SCI
8. Jia H#, Du P#, Yang H#, Zhang Y#, Wang J, Zhang W, Han G, Han N, Yao Z, Wang H, Zhang J, Wang Z, Ding Q, Qiang Y, Barbut F, Gao GF, Cao Y*, Cheng Y*, Chen C*.Nosocomial transmission of Clostridium difficile ribotype 027 in a Chinese hospital, 2012-2014, traced by whole genome sequencing. BMC Genomics. 2016,17(1) :405.SCI
9. Ni M#, Chen C#, Qian J#, Xiao HX, Shi WF, Luo Y, Wang HY, Li Z, Wu J, Xu PS, Chen SH, Wong G, Bi Y, Xia ZP, Li W, Lu HJ, Ma J, Tong YG, Zeng H, Wang SQ*, Gao GF*, Bo XC*, Liu D*.Intra-host dynamics of Ebola virus during 2014. Nature Microbiology. 2016,1:16151.SCI
10. Cao B#, Zhang Y#, Bian F#, Cheng Y#, Wang J, Jia H, Zhang W, Lu J, Chen C*, Du P* .Detection of Clostridium difficile toxin genes by PCR: sequence variation may cause false-negative results. Journal of Medical Microbiology. 2015,64(2):195-197.SCI
11. Wang H#, Du P#, Li J#, Zhang Y, Zhang W, Han N, Woo PC, and Chen C*.Comparative analysis of microbiome between accurately identified 16S rDNA and quantified bacteria in simulated samples. J Med Microbiol. 2014,63(Pt 3):433-440.SCI
12. Zhang W#, Du P#, Zheng H, Yu W, Wan L, Chen C*.Whole-genome sequence comparison as a method for improving bacterial species definition. J Gen Appl Microbiol. 2014,60(2):75-78.SCI
13. Du P#, Cao B#, Wang J#, Li W, Jia H, Zhang W, Lu J, Li Z, Yu H, Chen C*, and Cheng Y*.Sequence Variation in tcdA and tcdB of Clostridium difficile: ST37 with Truncated tcdA Is a Potential Epidemic Strain in China. J Clin Microbiol. 2014,52(9):3264-3270.SCI
14. Zhang W#, Zhang Y#, Zheng H#, Pan Y#, Liu H, Du P, Wan L, Liu J, Zhu B*, Zhao G*, Chen C*, and Wan K*.Genome sequencing and analysis of BCG vaccine strains.. PloS One. 2013,8(8):e71243.SCI
15. Yan Q#, Zhang J#, Chen C#, Zhou H, Du P, Cui Z, Cen R, Liu L, Li W, Cao B, Lu J*, and Cheng Y*.Multilocus sequence typing (MLST) analysis of 104 Clostridium difficile strains isolated from China. Epidemiol Infect. 2013,141(1):195-199.SCI
16. Liu H#, Jiang Y#, Dou X#, Wang H#, Zhao X, Zhang W, Wan L, Zhang Z, Chen C*, and Wan K*.pstS1 polymorphisms of Mycobacterium tuberculosis strains may reflect ongoing immune evasion.. Tuberculosis. 2013,93(5):475-481.SCI
17. Chen C#, Zhang W#, Zheng H#, Lan R#, Wang H, Du P, Bai X, Ji S, Meng Q, Jin D, Liu K, Jing H, Ye C, Gao GF, Wang L, Gottschalk M, and Xu J*.Minimum core genome sequence typing of bacterial pathogens: a unified approach for clinical and public health microbiology. J Clin Microbiol. 2013, 51(8):2582-2591.SCI
18. Jin D#, Chen C#, Li L#, Lu S#, Li Z#, Zhou Z, Jing H, Xu Y, Du P, Wang H, Xiong Y, Zheng H, Bai X, Sun H, Wang L, Ye C, Gottschalk M, and Xu J*.Dynamics of fecal microbial communities in children with diarrhea of unknown etiology and genomic analysis of associated Streptococcus lutetiensis.. BMC Microbiol. 2013,13(1):141.SCI
19. Jiang H#, Du P#, Zhang W, Wang H, Zhao H, Piao D, Tian G, Chen C*, and Cui B*.Comparative genomic analysis of Brucella melitensis vaccine strain M5 provides insights into virulence attenuation.. PloS One. 2013,8(8):e70852.SCI
20. Chen C#, Lu S#, Du P#, Wang H, Yu W, Song H, and Xu J*.Silent geographical spread of the H7N9 virus by online knowledge analysis of the live bird trade with a distributed focused crawler. . Emerg Microbes Infect. 2013, 2(12):e89.SCI
21. Zhang W#, Rong C#, Chen C*, and Gao GF*.Type-IVC secretion system: a novel subclass of type IV secretion system (T4SS) common existing in gram-positive genus Streptococcus. PloS One. 2012,7(10):e46390.SCI
22. Du P#, Zhang W#, Wang H, and Chen C*.Comparative genomic analysis of Escherichia coli O104:H4 stx2 prophage reveals a potential new method to identify virulence factors. Genome. 2012,55(9):697-700.SCI
主编或副主编的著作/译著
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