姓名：张凯 性别：男 职称：主任医师、教授 招生院所：附属天坛医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：外科学（神外）(博) 外科学（神外）(硕) 研究方向名称： 癫痫、运动障碍疾病、颅神经疾病与疼痛 电子信箱：zhangkai62035@sina.com


社会任职
1. 中国医师协会神经调控专业委员会委员
2. 中国抗癫痫协会青年委员会委员
3. 北京医学会脑电图及神经电生理学分会青委会委员
4. 北京医学会神经外科学分会功能学组委员
5. 中华医学会神经外科分会功能神经外科专家委员会秘书委员
6. 中国抗癫痫协会神经调控专业委员会副主任委员
7. 中国医师协会神经外科医师分会功能神经外科专家委员会副主任委员
个人简历
1. 198809-199507:白求恩医科大学临床医学七年制专业 获硕士学位
2. 199507-199708:白求恩医科大学第三临床学院神经外科 任职住院医师
3. 199709-200007:首都医科大学 获博士学位
4. 200007-200510:首都医科大学附属北京天坛医院 任职主治医师
5. 200510-201012:首都医科大学附属北京天坛医院 副主任医师
6. 201012-:首都医科大学附属北京天坛医院 主任医师
7. 201111-201411:首都医科大学附属北京天坛医院 副教授
8. 201206-201811:首都医科大学附属北京天坛医院 功能神经外科副主任
9. 201811-:首都医科大学附属北京天坛医院 癫痫外科主任
重要学术论文
1. Mo Jiajie, Zhang Jian-guo, Li Wenling, Chen Chao, Zhou Najing, Hu Wenhan, Zhang Chao, Wang Yao, Wang Xiu, Liu Chang, Zhao Baotian, Zhou Junjian, Zhang Kai.Clinical Value of Machine Learning in the Automated Detection of Focal Cortical Dysplasia Using Quantitative Multimodal Surface-Based Features. Frontiers in Neuroscience. 2019,12:1008.SCI
2. Wen-han Hu, Bao-tian Zhao, Chao Zhang, Xiu Wang, Lin Sang, Xiao-qiu Shao, Hui Qiao, Jian-guo Zhang, Kai Zhang*.Focal cortical dysplasia II-related seizures originate from the bottom of the dysplastic sulcus: A stereoelectroencephalography study.. Clinical Neurophysiology. 2019,130(9):1596-1603.SCI
3. Xiu Wang, Wenhan Hu, Aileen McGonigal, Chao Zhang, Lin Sang, Baotian Zhao, Tao Sun, Feng Wang, Jian-guo Zhang, Xiaoqiu Shao*, Kai Zhang*.Electroclinical features of insulo-opercular epilepsy: an SEEG and PET study. Annals of Clinical and Translational Neurology. 2019,6(7):1165-1177.SCI
4. Jiajie Mo, Zhenyu Liu, Kai Sun, Yanshan Ma, Wenhan Hu, Chao Zhang, Yao Wang, Xiu Wang, Chang Liu, Baotian Zhao, Kai Zhang#, Jianguo Zhang#, Jie Tian#.Automated detection of hippocampal sclerosis using clinically empirical and radiomics features. Epilepsia. 2019,60:2519-2529.
5. Yao Wang, Xiu Wang, Jia‐jie Mo, Lin Sang, Bao‐tian Zhao, Chao Zhang, Wen‐han Hu, Jian‐guo Zhang, Xiao‐qiu Shao, Kai Zhang*.Symptomatogenic zone and network of oroalimentary automatisms in mesial temporal lobe epilepsy.. Epilepsia. 2019,60(6):1150-1159.SCI
6. Jia-Jie Mo, Wen-Han Hu, Chao Zhang, Xiu Wang, Chang Liu, Bao-Tian Zhao, Jun-Jian Zhou, Kai Zhang*.Motor cortex stimulation: a systematic literature-based analysis of effectiveness and case series experience. BMC Neurology. 2019,19(48):1-9.SCI
7. Chao Zhang, Bao-tian Zhao, Aileen McGonigal, Wen-han Hu, Xiu Wang, Xiao-qiu Shao, Yan-shan Ma, Jian-guo Zhang, Kai Zhang*.Superior Frontal Sulcus Focal Cortical Dysplasia Type II: An MRI, PET, and Quantified SEEG Study. frontiers in Neurology. 2019,10:1253.SCI
8. Mo jiajie, Hu Wenhan, Zhang Chao, Wang Xiu, Liu Chang, Zhao Baotian, Zhou Junjian, Zhang Kai.Value of stereo-electroencephalogram in reoperation of patients with pharmacoresistant epilepsy: a single center, retrospective study. British journal of neurosurgery. 2018,32(6):663-670.SCI
9. 桑林，张凯*，张建国，马延山，邵晓秋，张弨，赵宝田，胡文瀚，郑重，周峰.PET-MRI影像融合技术在药物难治性癫痫术前评估中的价值. 中华神经外科杂志. 2017,33（6）:559-563.核心期刊
10. 王垚，王秀，张弨，刘畅，张凯*，张建国，杨海峰.利莫那班对颅脑外伤模型大鼠癫痫易感性的影响. 吉林大学学报（医学版）. 2016,42(3):435-438.核心期刊
11. Wang X, Wang Y, Zhang C, Liu C, Zhao B, Wei N, Zhang JG, Zhang K*.CB1 Receptor Antagonism Prevents Long-Term Hyperexcitability after Head Injury by Regulation of Dynorphin-KOR System and mGluR5 in Rat Hippocampus. Brain Research. 2016,1646:174-181.SCI
12. Xiu Wang#, Chao Zhang#, Yao Wang, Chang Liu, Baotian Zhao, Jian-guo Zhang, Wenhan Hu, Xiaoqiu Shao, Kai Zhang*.Deep brain stimulation for craniocervical dystonia (Meige Syndrome): A report of four patients and a literature-based analysis of its treatment effects. Neuromodulation. 2016,19:818-823.SCI
13. Xiu Wang#, Yao Wang#, Chao Zhang, Chang Liu, Hai-Feng Yang,Wen-Han Hu, Jian-Guo Zhang, Kai Zhang*.Endogenous cannabinoid system alterations and their role in epileptogenesis after brain injury in rat. Epilepsy Research. 2016,128:35-42.SCI
14. Wang X, Zhang C, Wang Y, Hu W, Shao X, Zhang JG, Zhang K*.Prognostic factors for seizure outcome in patients with MRI-negative temporal lobe epilepsy: A meta-analysis and systematic review. Seizure. 2016,38:54-62.SCI
15. Meng DW, Zhang JG, Zheng Z, Wang X, Luo F*, Zhang K*.Chronic Bilateral Sphenopalatine Ganglion Stimulation for Intractable Bilateral Chronic Cluster Headache: A Case Report. Pain Physician. 2016,19(4):637-642.SCI
16. 史增敏，张凯*，张建国，马延山，桑林，郑重，周峰，解飞，王秀.大脑半球切除术治疗顽固性癫痫的随访研究. 中华神经外科杂志. 2016,32(10):984-988.核心期刊
17. Chao Zhang#，Nai-Li Wei#，Yao Wang，Xiu Wang，Jian-Guo Zhang，Kai Zhang*.Deep brain stimulation of the nucleus accumbens shell induces anti-obesity effects in obese rats with alteration of dopamine neurotransmission. Neuroscience Letters. 2015,589:1-6.SCI
18. Chao Zhang#，Yao Wang#，Xiu Wang，Jian-Guo Zhang，Jing-Jun Li，Wen-Han Hu，Kai Zhang*.Sporadic meningioangiomatosis with and without meningioma: analysis of clinical differences and risk factors for poor seizure outcomes. Acta Neurochirurgica. 2015,157:841-853.SCI
19. N. WEI#，Y. WANG#，X. WANG，Z. HE，M. ZHANG，X. Zhang，Y. Pan，J. Zhang，Z. Qin，K. Zhang*.The different effects of high-frequency stimulation of the nucleus accumbens shell and core on food consumption are possibly associated with different neural responses in the lateral hypothalamic area . Neuroscience. 2015,301:312-322.SCI
20. 刘畅，王慧敏，张建国，张弨，王秀，赵宝田，杨岸超，孟凡刚，张凯*.脑深部电刺激术治疗颅脑创伤后肌张力障碍长期随访研究. 中国现代神经疾病杂志. 2015,15（10）:795-799.核心期刊
21. Naili Wei，Yanfei Jia，Xiu Wang，Yinian Zhang，Guoqiang Yuan，Baotian Zhao，Yao Wang，Kai Zhang*，Xinding Zhang，Yawen Pan，Jianguo Zhang.Risk Factors for Postoperative Fibrinogen Deficiency after Surgical Removal of Intracranial Tumors. PLos One. 2015,10（12）:e**.SCI
22. ZHENXING SUN#，KAI ZHANG#，HUANCONG ZUO，DAN YUAN，YAXING SUN，ZHIQIANG CUI，JIN WANG*.Predictors of prognosis in patients with temporal lobe epilepsy after anterior temporal lobectomy. Experimental and Therapeutic Medicine. 2015,10:1896-1902.SCI
23. 王秀，张凯*，张弨，魏乃礼，王垚，刘畅，赵宝田，胡文瀚，张建国.高频电刺激伏隔核壳部对肥胖大鼠摄食相关激素的影响. 中华神经外科杂志. 2015,31（1）:76-79.核心期刊
24. 王垚，张凯*，张弨，王秀，张建国，孙振荣，孟凡刚.合并海马硬化的儿童颞叶癫痫手术效果分析 . 中华神经外科杂志. 2014,30（8）:788-791.核心期刊
25. Sun Zhenxing，Yuan Dan，Sun Yaxing，Zhang Jianguo，Zuo Huancong，Zhang Kai*.Clinical curative effect analysis and predictors of prognosis in patients with temporal lobe epilepsy after anterior temporal lobectomy: results after five years. Chinese Medical Journal. 2014,127（14）:2588-2593.SCI
26. Chao Zhang#，Xiu Wang#，Yao Wang，Jian-guo Zhang，Wenhan Hu，Ming Ge，Kai Zhang*，Xiaoqiu Shao*.Risk factors for post-stroke seizures: A systematic review and meta-analysis. Epilepsy Research. 2014,108:1806-1816.SCI
27. 孙振兴，张凯*，张超，胡文瀚，张颖，张建国.液压打击诱导外伤后癫痫大鼠海马病理改变的初步探索. 立体定向和功能性神经外科杂志. 2013,02:69-74.核心期刊
28. Zhang K，Hu WH，Zhang C，Meng FG，Chen N，Zhang JG*..Predictors of seizure freedom after surgical management of tuberous sclerosis complex: A systematic review and meta-analysis.. Epilepsy Research. 2013,105（3）:377-383.SCI
29. 李敬军，马羽，胡文瀚，张凯*，张建国，张颖，孟凡刚.丘脑底核高频电刺激对偏侧帕金森猴苍白球内侧部中氨基酸神经递质含量的影响. 立体定向和功能性神经外科杂志. 2012,25（2）:68-71.核心期刊
30. 张弨，张建国，张凯*，马羽，葛明，孟凡刚，胡文瀚，杨岸超.丘脑底核电刺激术治疗原发性肌张力障碍. 中国微侵袭神经外科杂志 . 2012,17（7）:302-304.核心期刊
31. 李敬军，张凯*，马羽，张建国，张颖，胡文瀚，孟凡刚.高频电刺激丘脑底核对偏侧帕金森病猴模型苍白球内侧部神经元放电的影响. 中华神经医学杂志. 2012,11（5）:459-463.核心期刊
32. 孙振兴，张建国，张凯*，葛明，孟凡刚，孙振荣.MRI影像改变对颞叶癫痫术后疗效的影响. 中华神经外科杂志. 2010,26(6):490-493.核心期刊
33. Zhang K, Bhatia S, Oh MY, Cohen D, Angle C, Whiting D..Long-term results of thalamic deep brain stimulation for essential tremor.. Journal of Neurosurgery. 2010,112(6):1271-1276.SCI
34. 孙振兴，张凯*，张超，胡文瀚，张颖，张建国.外侧液压打击诱导大鼠外伤后癫痫模型的制作. 立体定向和功能性神经外科杂志. 2010,23(3):146-150.核心期刊
35. Zhang K, Bhatia S, Oh M, Whiting D.Epidural anesthesia for placement of spinal cord stimulation with paddle-type electrode.. stereotactic and functional neurosurgery. 2009,87(5):292-296.SCI
36. 马羽,张凯*,张建国,胡文瀚,孟凡刚,张颖,张东.MPTP偏侧恒河猴帕金森病模型研究. 立体定向和功能性神经外科杂志. 2008,21:212-215.核心期刊
37. 张凯,张建国,马羽,胡文瀚,葛明,徐露.丘脑底核电刺激治疗继发性肌张力障碍. 中华神经外科杂志. 2006,22(12):711-713.核心期刊
38. 张凯,张建国,葛明,冯涛.丘脑底核电刺激治疗苍白球毁损术后的帕金森病. 中国神经精神疾病杂志. 2006,32(6):507-510.核心期刊
主编或副主编的著作/译著
1. 《迷走神经刺激术》,主编,人民卫生出版社,2019.1
2. 《癫痫磁共振成像》,副主译,人民卫生出版社,201707
3. 《神经调控技术与应用》,副主编,人民卫生出版社,201611
4. 《颞叶癫痫的外科问题》,副主编,辽宁科学技术出版社,201607
重要奖项
1. 脑起搏器关键技术、系统与临床应用 国家科学技术进步一等奖 国务院 201901
2. 脑起搏器关键技术、系统与临床应用 北京市科学技术奖 一等奖 201512
3. 脑深部电刺激作用机制研究及其在锥体外系疾病中的应用 教育部高等学校科学技术奖 二等奖 201005
4. 脑深部电刺激治疗运动障碍性疾病及其相关研究 中华医学科技奖 二等奖 200905
5. 脑深部电刺激治疗帕金森病及其相关研究 北京市科技进步奖 二等奖 200605