姓名：赵元立 性别：男 职称：主任医师、教授 招生院所：附属天坛医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：外科学（神外）(博) 外科学（神外）(硕) 研究方向名称：脑血管疾病及老年肿瘤 电子信箱：zhaoyl@ccmu.edu.cn


社会任职
1. 全国青联委员
2. 北京医学会神经外科专业委员会委员兼秘书
3. 中华医学会神经外科学分会工作秘书、青年委员会副主任委员
4. 北京市丰台区政协常委
5. Neurosurgery杂志国际编委
6. World Neurosurgery杂志审稿人
7. Chinese Neurosurgical Journal杂志编辑部主任
8. 美国神经外科学会（AANS）国际会员
9. 亚洲神经外科医师学会（ACNS）教育委员会委员
10. 世界神经外科联盟（WFNS）教育委员会委员
11. 中华医学会神经外科学分会第八届委员会全国委员
12. 中国中西医结合学会神经外科专业委员会副主任委员
13. 中国卒中学会医疗质量与促进分会委员会副主任委员
个人简历
1. 198808-199607:中国协和医科大学 八年制医学专业
2. 199608-:首都医科大学附属北京天坛医院 神经外科
3. 199903-199904:美国Harvard University Massachusetts General Hospital神经外科 访问
4. 200112-200202:美国 Mayo Clinic神经外科 访问
5. 200212-200302:美国凤凰城Barrow Neurological Institute神经外科 访问
6. 200501-201206:首都医科大学附属北京天坛医院神经外科中心 脑血管疾病及老年肿瘤病区主任
7. 200703-:首都医科大学附属北京天坛医院 神经外科博士生导师
8. 200803-200805:美国Johns Hopkins Hospital神经肿瘤科 访问
9. 200806-200809:北京奥组委奥运村综合诊所 经理助理
10. 201401-:国家神经系统疾病临床医学研究中心 项目负责人
11. 201510-:北京天坛医院-北京大学国际医院神经外科合作病房 病区主任
重要学术论文
1. Hao Q, Wang H, Lu JL, Ma L, Chen XL, Ye X, Zhao YH, Li MT, Chen Y, Zhao YL*.Activin Receptor-Like Kinase 1 Combined With VEGF-A Affects Migration and Proliferation of Endothelial Cells From Sporadic Human Cerebral AVMs. Front Cell Neurosci. 2019,12(525):doi: 10.3389/fncel.2018.00525..SCI
2. Zhao Y, Li J, Lu J, Zhang Q, Zhang D, Wang R, Zhao Y*, Chen X*.Predictors of neoangiogenesis after indirect revascularization in moyamoya disease: a multicenter retrospective study.. J Neurosurg. 2019,25:1-11.SCI
3. Li K, Kong DS, Zhang J, Wang XS, Ye X, Zhao YL*.Association between ELP4 rs986527 polymorphism and the occurrence and development of intracranial arachnoid cyst. brain and behavior. 2019,9(12):e01480:-.SCI
4. Zhao Y, Lu J, Yu S, Li J, Deng X, Zhang Y, Zhang D, Wang R, Wang H, Zhao Y.Comparison of Long-Term Effect Between Direct and Indirect Bypass for Pediatric Ischemic-Type Moyamoya Disease: A Propensity Score-Matched Study. Frontiers in Neurology. 2019,10:795:-.SCI
5. Hao Q, Hao F, Hu Y, Wang TT, Zheng J, Gao Y, Zhao YL*.Overexpression of Sox2 Gene Enhances Neuronal Differentiation of Adult Human Bone Marrow Stem Cells. 神经解剖学杂志. 2019,无:无.核心期刊
6. Zhao Y#, Yu S#, Li J, Lu J, Zhang Q, Zhang D, Wang R, Zhao Y*.Modified encephalo-duro-periosteal-synangiosis (EDPS) for the revascularization of anterior cerebral artery territory in moyamoya disease: A single-center experience. Clin Neurol Neurosurg. 2019,178:86-92.SCI
7. Chen Y, Ma L, Lu J, Chen X, Ye X, Zhang D, Zhang Y, Wang R, Zhao Y*.Postoperative hemorrhage during the acute phase after direct or combined revascularization for moyamoya disease: risk factors, prognosis, and literature review. Journal of Neurosurgery . 2019,18:1-10.SCI
8. Lu J, Zhao Y, Ma L, Chen Y, Li M, Chen X, Ye X, Wang R, Zhao Y*.Predictors and clinical features of transient neurological events after combined bypass revascularization for moyamoya disease. clinical neurology and neurosurgery. 2019,186:105505:-.SCI
9. Lu J, Zhao Y, Ma L, Chen Y, Li M, Ye X, Wang R, Chen X*, Zhao Y**.Multimodal neuronavigation-guided precision bypass in adult ischaemic patients with moyamoya disease: study protocol for a randomised controlled trial. BMJ open. 2019,9(3):e025566:-.SCI
10. Li Z, Lu J, Ma L, Wu C, Xu Z, Chen X, Ye X, Wang R, Zhao Y*.dl-3-n-butylphthalide for alleviation of neurological deficit after combined extracranial-intracranial revascularization for moyamoya disease: a propensity score-matched analysis. Journal of Neurosurgery . 2019,15:1-13.SCI
11. Li K, Zhang J, Wang XS, Ye X, Zhao YL*.A systematic review of effects and complications after transsphenoidal pituitary surgery: endoscopic versus microscopic approach. minimally invasive therapy & allied technologies. 2019,8:1-9.SCI
12. Xia DJ, Zhang Z, Zhao YL*.Acteoside attenuates oxidative stress and neuronal apoptosis in rats with focal cerebral ischemia reperfusion injury. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2018,41(11):1645-1651.SCI
13. Qiang Hao, Xiao-lin Chen, Li Ma, Tong-Tong Wang, Yue Hu, Yuan-Li Zhao*.Procedure for the isolation of endothelial cells from human cerebral arteriovenous malformation(cAVM) tissues. Frontiers in Cellular Neuroscience. 2018,doi:10.3389/fncel.2018.00030:fncel.2018.00030.SCI
14. 赵元立*，郝强..脑动静脉畸形的复合手术治疗新策略. 临床外科杂志. 2018,26(7):10.3969/j.issn.1005-6483.2018.07.003.核心期刊
15. Zhao Y, Zhang Q, Wang S, Zhang D, Zhang Y, Zhao YL*.Comparison of radiological and clinical characteristics between blood blister-like aneurysms (BBAs) and non-blister aneurysms at the supraclinoid segment of internal carotid artery . Neurosurg Rev . 2018,无:doi: 10.1007/s10143-018-1002-9..SCI
16. Zhao Y, Zhang Q, Zhang D, Wang S, Zhang Y, Zhao YL*.Comparison of Dolenc and pterional approach in the microsurgery for blood blister-like aneurysms (BBAs) of internal carotid artery. . J Clin Neurosci. 2018,61:142-146.SCI
17. Zhao Y, Lu J, Zhang Q, Zhang Y, Zhang D, Wang R, Zhao YL*.Time Course of Neoangiogenesis After Indirect Bypass Surgery for Moyamoya Disease : Comparison of Short-term and Long-term Follow-up Angiography.. Clin Neuroradiol . 2018,无:doi: 10.1007/s00062-018-0748-3..SCI
18. Wang L, Ye X, Hao Q, Ma L, Chen X, Wang H, Zhao YL*.Three-dimensional intracranial middle cerebral artery aneurysm models for aneurysm surgery and training. J Clin Neurosci . 2018,50:77-82.SCI
19. Liang Wang#, Xun Ye#, Qiang Hao, Li Ma, XiaoLin Chen,Hao Wang,Zhao YL*.Three-demensinonal intracranial middle cerebral artery aneurysm models for aneurysm surery and training. Journal of Clinical Neuroscience. 2018,DOI:10.1016/j.jocn:DOI:10.1016/j.jocn.SCI
20. Hao Q, Chen XL, Ma L, Ye X, Wang H, Wang TT, Hu Y, Zhao YL*.In vitro characteristics of endothelial cells prepared from human cerebral arteriovenous malformation lesions using a novel method . Microvascular Research. 2018,116:57-63.SCI
21. Wang X , Hao Q , Zhao Y* , Guo Y*, Ge W*.Dysregulation of cell-cell interactions in brain arteriovenous malformations: A quantitative proteomic study. Proteomics Clin Appl. 2017,11(5-6):5-6.SCI
22. Chen XL , Chen Y , Ma L , Burkhardt JK , Wardell T , Wang C , Guo G , Wang S , Zhao YL*.Translucent appearance of middle cerebral artery bifurcation aneurysms is a risk factor for intraoperative aneurysm rupture during clipping. World Neurosurg. 2017,S1878-8750(17):30120-1.SCI
23. Wang L , Ye X , Hao Q , Chen Y , Chen X , Wang H , Wang R , Zhao Y* , Zhao J.Comparison of Two Three-dimensional Printed Models of Complex Intracranial Aneurysms for Surgical Simulation. World Neurosurg. 2017,S1878-8750(17):30606-X.SCI
24. Ma L , Chen XL , Chen Y , Wu CX , Ma J , Zhao YL*.Subsequent haemorrhage in children with untreated brain arteriovenous malformation: Higher risk with unbalanced inflow and outflow angioarchitecture. Eur Radiol. 2017,DOI: 10.1007/s00330-016-4645-3:2868-2876.SCI
25. Ma L , Kim H, Chen XL, Wu CX, Ma J, Su H, Zhao Y*.Morbidity after Hemorrhage in Children with Untreated Brain Arteriovenous Malformation. Cerebrovasc Dis. 2017,43(5-6):231-241.SCI
26. Ma L , Chen XL, Ma J, Zhao YL*.The Associated Venous Anomalies Variant and Adjacent Brain Function on Iron Sensitive Image Indicate Surgical Risk of Cavernous Malformation. Neurol Med Chir (Tokyo). 2016,56(1):9-20.SCI
27. Zheng Huang, Xuehu Ding, Weidong Men, Dong Zhang, Yuanli Zhao*.Clinical features and outcomes in 154 patients with haemorrhagic moyamoya disease: comparison of conservative treatment and surgical revascularization . Neurol Res . 2015,37（10）:886-92 .SCI
28. Hongji Wu, Tao Yu, Shuo Wang, Jizong Zhao, Yuanli Zhao*.Surgical Treatment of Cerebellar Cavernous Malformations: A Single-Center Experience with 58 cases . WORLD NEUROSURGERY . 2015,84（4）:1103-1111 .SCI
29. Geng Guo, Cheng-liang Zhong, Yang Liu, Xing-gangMao, Zheng Zhang,Yuan-li Zhao*.Overexpression of FRAT1 Is Associated with Malignant Phenotype and Poor Prognosis in Human Gliomas . Disease Markers. 2015,289750:1-8.SCI
30. L. Ma, Z. Huang, X.-L. Chen, J. Ma, X.-J. Liu, H. Wang, X. Ye, S.-L. Wang, Y. Cao, S. Wang, Y.-L. Zhao*, and J.-Z. Zhao.Periventricular Location as a Risk Factor for Hemorrhage and Severe Clinical Presentation in Pediatric Patients with Untreated Brain Arteriovenous Malformations. American journal of neuroradiology. 2015,36（8）:1550-7.SCI
31. Zhao Shangfeng，Fu Jidi，Liu Fang，Rastogi Radhika，Zhang Jialiang，Zhao Yuanli*.Small interfering RNA directed against CTMP reduces acute traumatic brain injury in a mouse model by activating Akt.. Neurological Research. 2014,36（5）:483-490.SCI
32. Bai Jie，Wang Ya-Jie，Liu Li，Zhao Yuan-Li*.Ephrin B2 and EphB4 selectively mark arterial and venous vessels in cerebral arteriovenous malformation.. Journal ofInternational Medical Research. 2014,42（2）:405-415.SCI
33. Chu C, Huang X, Chen CT, Zhao Y*, Luo JJ, Gray BD, Pak KY, Dun NJ*.In vivo imaging of brain infarct with the novel fluorescent probe PSVue 794 in a rat middle cerebral artery occlusion-reperfusion model. Molecular Imaging. 2013,12(1):8-16.SCI
34. Ren Z# *，Chen X#，Yang J，Kress B T，Tong J，Liu H，Takano T，Zhao Y*，Nedergaard M*.Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter. . Neuroscience. 2013,241:89-99.SCI
35. Yi Guo, Shi-Wei Qumu, Osman Arikan Nacar, Jin-Yan Yang, Jiang Du, Deniz Belen, Lin Pan, Yuan-li Zhao*.Human brain arteriovenous malformations are associated with interruptions in elastic fibers and changes in collagen content. Turkish Neurosurgery. 2013,23(1):10-15.SCI
36. Li T, Zhang J, Liu RY, Lian ZG, Chen XL, Ma L, Sun HM, Zhao YL*..The role of the sonic hedgehog signaling pathway in early brain injury after experimental subarachnoid hemorrhage in rats. Neuroscience Letters. 2013,552:81-86.SCI
37. Wang H, Dong H, Kang CG, Lin C, Ye X, Zhao YL*.Preliminary exploration of the development of a collagenous artificial dura mater for sustained antibiotic release. Chinese Medical Journal. 2013,126(17):3329-3333.SCI
38. Ye X, Liu XJ, Ma L, Liu LT, Wang WL, Wang S, Cao Y, Zhang D, Wang R, Zhao JZ, Zhao YL*.Clinical values of intraoperative indocyanine green fluorescence video angiography with Flow 800 software in cerebrovascular surgery. Chinese Medical Journal. 2013,126(22):4232-4237.SCI
39. Jie Bai, Yuan-li Zhao*, Rong Wang, Dong Zhang, Shuo Wang, Ji-zong Zhao, Jun Wu.Regional cerebral perfusion and ischemic status after standard superficial temporal artery–middle cerebral artery (STA-MCA) bypass surgery in ischemic cerebrovascular disease. Child's Nervous System. 2012,28(4):579-586.SCI
40. Shangfeng Zhao, Jidi Fu, Xiangrong Liu, Tony Wang, Jialiang Zhang, Yuanli Zhao*.Activation of Akt/GSK-3beta/beta-catenin signaling pathway is involved in survival of neurons after traumatic brain injury in rats. Neurological Research. 2012,34(4):400-407.SCI
41. Jie Tang, Carol Chen, Yuanli Zhao*.Neurosurgery center of Beijing Tiantan Hospital, flagship of neurosurgery in China. World Neurosurgery. 2011,75(3):377-382.SCI
42. 叶迅，朱琳，唐光昕，于书卿，王硕，赵继宗，赵元立*.纯钛表面梯度生物活性涂层材料生物相容性研究. 中华神经外科疾病研究杂志. 2011,10（6）:543-547.核心期刊
43. 褚纯，赵元立，赵继宗，赵春华，王强，王薇，胡燕，周佳彦，杨先达*.人类脂肪干细胞对慢性脑缺血大鼠认知功能障碍的影响. 中国卒中杂志. 2010,5（3）:192-196.核心期刊
44. 王昊，李海洋，杨先达，赵元立*.外源性NMDA对成年大鼠被动回避学习记忆的影响. 中华神经医学杂志. 2009,8(1):13-15.核心期刊
45. 王昊，李海洋，赵元立* .难以用介入方法治疗的颅内动脉瘤27例分析 2009 89(5):331-334. 中华医学杂志. 2009,89(5):331-334.核心期刊
46. 褚纯，张东，李德志，赵元立*.大脑半球毛细血管扩张症2例及文献回顾. 中国卒中杂志. 2008,3(10):726-729.核心期刊
47. Yang M, Wang S, Zhao Y, Zhao J* .Management of intracranial aneurysm in children: clipped and coiled.. Childs Nerve System. 2008,24(9):1005-1012.SCI
48. Jinhu Yang, Jianping Dai*, Xin Liu, Yuanli Zhao.Dynamic Enhancement Features of Cavernous Sinus Cavernous Hamangiomas on Conventional Contrast-Enhanced MR Imaging. American Journal of Neuroradiology. 2008,29:577-81.SCI
49. 叶迅,赵元立,朱琳,唐光昕,李朝征,李京生,于书卿,赵继宗.颅骨修补材料钛金属表面梯度生物活性涂层的生物相容性研究. 北京医学. 2008,32(1):8-12.核心期刊
50. Jizong Zhao*, Yonggang Wang, Shuai Kang, Shuo Wang, Jiangfei Wang, Rong Wang, Yuanli Zhao.The benefit of neuronavigation for the treatment of patients with intracerebral cavernous malformations. Neurosurgical Review. 2007,30:313-319.SCI
51. Yuanli Zhao*,Shuqing Yu,Rong Wang,Jizong Zhao.Clinical application of a neuronagivation system in transsphenoidal surgery of pituitary macroadenoma. Neurosurgical Review. 2006,29(4):306-312.SCI
52. 于兰冰,王硕,赵元立,赵继宗.微创手术治疗老年颅内动脉瘤的预后分析. 中华医学杂志. 2006,86(31):2209-2211.核心期刊
53. Jizong Zhao*, Shuo Wang, Yuanli Zhao, Dali Sui, Yan Zhang, Jie Tang, Wei Lui.Microneurosurgical management of carotid-ophthalmic aneurysms. Journal of Clinical Neurosurgery. 2006,13:330-333.SCI
54. Y.L.Zhao*,J.Y.Zhou,G.H.Zhu.Clinical experience with the noninvasive ICP monitoring system . Acta Neurochirurgica . 2005,Suppl 95:351-355.SCI
主编或副主编的著作/译著
1. 《神经科学精要》,主编,科学出版社,201512
2. 《神经外科手术操作系列教材 - 凹陷性颅骨骨折探查修补术》,主编,中华医学电子音像出版社,2012.3
3. 《神经外科手术操作系列教材 - 前交通动脉瘤夹闭术》,主编,中华医学电子音像出版社,2010.8
4. 《脑外科手术集－动脉瘤手术》,副主编,中国中医药出版社,200110
5. 《颅脑损伤与颅内压增高》,副主编,人民卫生出版社,200010
重要奖项
1. 第三届国之名医 国之名医优秀风范奖 - 201908
2. 首都医科大学附属北京天坛医院优秀研究生导师 2012.9
3. 颅脑手术中脑认知功能保护的微创神经外科学基础研究与临床应用 国家科学技术进步奖 二等奖 200912
4. 出血性脑卒中规范化外科技术推广及其HE机制和临床预测研究 教育部科学技术进步奖（推广类） 二等奖 200901
5. 北京市茅以升青年科技奖 - 200805
6. 微创神经外科技术的建立及其推广应用 中华医学科技奖 一等奖 200712
7. 北京市优秀青年知识分子 200610
8. 脑血管畸形的外科治疗及其形成和破裂出血机制的研究 国家科学技术进步奖 二等奖 200601
9. 微创神经外科技术平台的建立及临床应用 北京市科技进步奖 一等奖 200501
10. 颅内动脉瘤的外科治疗及其形成和破裂的基础研究 国家科学技术进步奖 二等奖 200401