姓名：沈叙庄 性别：女 职称：研究员、教授 招生院所：附属儿童医院 招生类型：科学学位(博) 科学学位(硕) 招生专业：病原生物学(博) 病原生物学(硕) 研究方向名称：感染性疾病病原及抗感染免疫研究 电子信箱：xuzhuangshen@163.com


社会任职
1. 中华医学会儿科分会呼吸学组成员
2. 卫生部传染病标准化专业委员会委员
3. 北京市药理学会抗感染药理专业委员会
4. 中国药学会高级会员
个人简历
1. 197703-198212:首都医科大学儿科系 学士
2. 198212-199011:首都医科大学附属北京儿童医院 住院医师
3. 198709-199006:首都医科大学儿科系 硕士研究生
4. 199012-199311:首都医科大学附属北京儿童医院 主治医师
5. 199312-200111:首都医科大学附属北京儿童医院 副研究员
6. 199604-199703:瑞典哥德堡大学医学微生物免疫系 访问
7. 200112-:首都医科大学附属北京儿童医院 研究员
重要学术论文
1. Li S, Ning X, Song W, Dong F, Zheng Y, Chen Q, Qiao Y, Li J, Wang L, Wang Q, Yue L, Wang A, Yu S, Yao K, Yang Y, Shen X*.Clinical and molecular characteristics of community-acquired methicillin-resistant Staphylococcus aureus infections in Chinese neonates. APMIS. 2015,123(1):28-36.SCI
2. 董燕红，李士朋，乔艳红，宁雪，曾婷，俞桑洁，姚开虎，高薇，袁琳，杨永弘，沈叙庄#.儿童耐甲氧西林金黄色葡萄球菌感染分离株毒力特征研究. 中华实用儿科临床杂志. 2015,30（10）:733-737.核心期刊
3. 李文婷,董燕红，宁雪，曾婷，俞桑洁，姚开虎，史伟，高薇，袁琳，杨永弘，沈叙庄#.新生儿侵袭性社区获得性金黄色葡萄球菌感染临床及分离株的分子特征. 中华实用儿科临床杂志. 2015,30(22):1692-1696.核心期刊
4. Qiao Y#, Ning X#, Chen Q, Zhao R, Song W, Zheng Y, Dong F, Li S, Li J, Wang L, Zeng T, Dong Y, Yao K, Yu S, Yang Y, Shen X*.Clinical and molecular characteristics of invasive community-acquired Staphylococcus aureus infections in Chinese children. BMC Infect Dis. 2014,14:582.SCI
5. 曾婷,王全意,吴琼,林弘睿,董燕红, 杨鹏，俞桑洁,姚开虎，杨永弘,沈叙庄.儿童A组β溶血链球菌主要毒力特征研究. 中华实用儿科临床杂志. 2014,29（16）:1235-1239.核心期刊
6. Li S, Sun J, Zhang J, Li X, Tao X, Wang L, Sun M, Liu Y, Li J, Qiao Y, Yu S, Yao K, Yang Y, Shen X*.omparative analysis of the virulence characteristics of epidemic methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from Chinese children: ST59 MRSA highly expresses core gene-encoded toxin. APMIS. 2014,122(2):101-114.SCI
7. Li S, Li J, Qiao Y, Ning X, Zeng T, Shen X*.Prevalence and invasiveness of community-acquired methicillin-resistant Staphylococcus aureus: a meta-analysis. Indian J Pathol Microbiol. 2014,57(3):418-422.SCI
8. 李娟，王群，王丽娟，孙明姣，李士朋，孙静，王传清，邓秋莲，郭跃杰，刘岚，李昌崇，尚云晓，杨永弘，沈叙庄*. 儿童社区获得性耐甲氧西林金黄色葡萄球菌肺炎分离株的多重耐药克隆研究.. 中国感染与化疗杂志. 2014,14（1).:32-37.核心期刊
9. 李士朋，李　娟，王丽娟，孙静，孙明娇，乔艳红，宁雪，曾婷，杨永弘，沈叙庄*. 儿童社区获得性耐甲氧西林金黄色葡萄球菌肺炎分离株分子及临床特征. 临床儿科杂志. 2013,31（6）:514-518.核心期刊
10. Yanhong Qiao, Fang Dong, Wenqi Song, Lijuan Wang, Yonghong Yang, Xuzhuang Shen*.Hospital- and community-associated methicillin-resistant Staphylococcus aureus: a 6-year surveillance study of invasive infections in Chinese childre. Acta Paediatrica. 2013,102(11):1081-1086.SCI
11. Juan Li, Lijuan Wang, Mingjiao Sun, Jing Sun, Yonghong Yang, Sangjie Yu, Kaihu Yao and Xuzhuang Shen *.Molecular and Clinical Characteristics of Clonal Complex 59 Meticillin-Resistant Staphylococcus aureus Infections in Mainland China.. PLOS ONE. 2013,8:e1.SCI
12. 孙明姣,王丽娟,刘颖超,李向梅,孙静,王传清,邓秋莲,郑跃杰,刘岚,李昌崇,尚云晓,赵长安,杨永弘,沈叙庄*.儿童社区获得性耐甲氧西林金黄色葡萄球菌皮肤软组织感染临床分离株的分子特征及耐药性研究. 中国感染与化疗杂志. 2013,13（1）:13-24.核心期刊
13. Li Xiangmei，Sun Jing，Wu Dejing，Wang Lijuan，Yang Yonghong，Wang Chuanqing，Liu Lan，Zhao Changan，Du Pengcheng，Yu Sangjie，Shen Xuzhuang*.Panton-Valentine leukocidin gene sequence variation and phage in methicillin-resistant and methicillin-susceptible Staphylococcus aureus from children in mainland China. Microbiology and Immunology. 2012,56（3）:155-162.SCI
14. Lijuan Wang,Yingchao Liu,Yonghong Yang,Guoying Huang,Chuanqing Wang,Li Deng,Yuejie Zheng,ZhouFu,Changcong Li,Yunxiao Shang,Changan Zhao,Mingjiao Sun,Xiangmei Li,Sangjie Yu,Xuzhuang Shen*.Multidrug-resistant clones of community-associated meticillin-resistant Staphylococcus aureus isolated from Chinese children and the resistance genes to clindamycin and mupirocin. Journal of Medical Microbiology. 2012,61（9）:1240-1247.SCI
15. Yingchao Liu, Wenjing Geng, Yonghong Yang, Chuanqing Wang, Yaojie Zheng, Yunxiao Shang, Dejing Wu, Xiangmei Li, Lijuan Wang, Sangjie Yu, Kaihu Yao， Xuzhuang Shen*.Susceptibility to and resistance determinants of fusidic acid in Staphylococcus aureus isolated from Chinese children with skin and soft tissue infections. fems immunology and medical microbiology. 2012,64（2）:212-218.
16. 孙静、李向梅、孙明姣、王丽娟、刘颖超、王传清、邓秋莲、刘 岚、杨永弘、沈叙庄*.儿科Panton-Valentine杀白细胞素基因阳性耐甲氧西林金黄色葡萄球菌分子特征及Panton-Valentine杀白细胞素基因多态性及耐药特征的研究. 实用儿科临床杂志. 2012,27(22):1707-1711.核心期刊
17. 刘颖超，耿文静，吴德静，李向梅，王传清，邓权，陆秋莲，郑跃杰，刘岚，李昌崇，尚云晓，赵长安，杨永弘，沈叙庄*.中国七城市儿童耐甲氧西林金黄色葡萄球菌感染分离株分子学特征的研究. 中华儿科杂志. 2012,50（1）:38-44.核心期刊
18. 李向梅，沈叙庄*.社区相关的耐甲氧西林金黄色葡萄球菌毒力因子的研究进展. 国际儿科学杂志. 2011,38(1):26-29.核心期刊
19. 李向梅，吴德静，耿文静，沈叙庄*.儿童金黄色葡萄球菌感染分离株致病基因和相关可移动遗传元件研究. 中国实用儿科杂志. 2011,26(8):572-577.核心期刊
20. 王群，杨永弘，沈叙庄*.肺炎患儿耐甲氧西林金黄色葡萄球菌分离株耐药性及基因分型研究. 中国实用儿科杂志. 2011, 26(3):183-186.核心期刊
21. 吴德静，沈叙庄等*.Superantigen gene profiles and presence of exfoliative toxin genes in community-acquired meticillin-resistant Staphylococcus aureus isolated from Chinese children. J Med Microbiol. 2011,60（1）:35-45.SCI
22. Wu D, Li X, Yang Y, Zheng Y, Wang C, Deng L, Liu L, Li C, Shang Y, Zhao C, Yu S, Shen X* .Superantigen gene profiles and presence of exfoliative toxin genes in community-acquired methicillin-resistant Staphylococcus aureus isolated from Chinese children. J Med Microbiol. . 2011,60(Pt1):35-45.SCI
23. Geng W, Yang Y, Wu D, Huang G, Wang C, Deng L, Zheng Y, Fu Z, Li C, Shang Y, Zhao C, Yu S, Shen XZ* .Molecular characteristics of community-acquired, methicillin-resistant Staphylococcus aureus isolated from Chinese children. . FEMS Immunol Med Microbiol . 2010,58(3):356-362.SCI
24. Geng W, Yang Y, Wu D, Zhang W, Wang C, Shang Y, Zheng Y, Deng L, Fu Z, Li X, Yu S, Shen XZ* .Community-acquired, methicillin-resistant Staphylococcus aureus isolated from children with community-onset pneumonia in China. . Pediatr Pulmonol . 2010,45(4):387-394.SCI
25. Geng W, Yang Y, Wang C, Deng L, Zheng Y, Shen XZ* .Skin and soft tissue infections caused by community-associated methicillin-resistant staphylococcus aureus among children in China. . Acta Paediatr . 2010,99(4):575-580.SCI
26. Feng LJ, Lin HR, Ma YL, Yang YH, Zheng YJ, Fu Z, Yu SJ, Yao KH, Shen XZ* .Macrolide-resistant Streptococcus pyogenes from Chinese pediatric patients in association with Tn916 transposons family over a 16-year period.. Diagnostic Microbiology and Infectious Disease. 2010,67(4):369-375.SCI
27. Wu DJ, Wang Q, Yang YH, Geng WJ, Wang Q, Yu SJ, Yao KH, Yuan L, Shen XZ*.Epidemiology and molecular characteristics of community-associated methicillin-resistant and -susceptible Staphylococcus aureus from skin/soft tissue infections in a children’s hospital in Beijing, China. Diagnostic Microbiology and Infectious Disease . 2010,67(1):1-8.SCI
28. 刘颖超，沈叙庄*.耐甲氧西林的金黄色葡萄球菌可移动基因元件-SCCmec的研究进展. 国际儿科学杂志. 2010,37（6）:651-654.核心期刊
29. Chenxi Han, Yonghong Yang, Minggui Wang, Aihua Wang, Quan Lu, Xiwei Xu, Chuanqing Wang, Lan Liu, Qiulian Deng，Shen XZ* .The prevalence of plasmid-mediated quinolone resistance determinants among clinical isolates of ESBL or AmpC-producing Escherichia coli from Chinese pediatric patients. . Microbiol Immunol. 2010,54(3):123-128.SCI
30. 王群，沈叙庄等*.儿童皮肤软组织感染金黄色葡萄球菌的临床特点与耐药情况. 实用儿科临床杂志. 2009,24（22）:1711-1713.核心期刊
31. 9、吕萍，徐樨巍，宋文琪，董方，杨永弘，沈叙庄*.儿童肠球菌耐药表型和耐药基因检测分. 中国实用儿科杂志. 2009,24（12）: 937-939.核心期刊
32. 8、韩晨曦’， 王爱华 ， 杨永弘 ， 陆 权 ， 王 艺。， 陈 沅 ， 邓 力 ， 邓秋莲 ， 张 泓：，王传清 ， 刘 岚 ， 徐樨巍 ， 沈叙庄*.儿科临床分离株中质粒介导喹诺酮类药物耐药基因qnr在产ESBLs或AmpC酶大肠埃希菌和肺炎克雷伯菌中的流行. 中国抗感染与化疗杂志. 2009,9(6):430-435.核心期刊
33. 4、Guanhua Xue, Lihua Yu, Shentao Li & Xuzhuang Shen*.Intranasal immunizationwithGBS surface proteinSip and ScpB induces special mucosal and systemic immuneresponses in mice . FEMS Immunol Med Microbio. 2009,5(12):1-9.SCI
34. 5、Y. MA, Y. YANG, M. HUANG Y. WANG, Y. CHEN L. DENG, S. YU, Q. DENG, H.ZHANG, C. WANG, L. LIU AND X. SHEN*..Characterisation of emm types and superantigens of Streptococcus pyogenes isolates from Chinese children over 12 years.. Epidemiology and Infection . 2009,137(10):1414-1419.SCI
35. 6、薛冠华1 李慎涛2 杨永弘1 于丽华1 王爱华1 王冠1 殷国荣3 沈叙庄*.B 族链球菌表面免疫原性蛋白的黏膜免疫效果. 中国生物制品学杂志. 2009,22(6):450-455.核心期刊
36. 10、马耀玲, 杨永弘, 俞桑洁, 姚开虎, 袁　林, 沈叙庄* .中国儿童A族链球菌感染菌株emm分型及超抗原基因谱分布. 基础医学与临床. 2009,29（11）:1166-1169.核心期刊
37. 7、董　方,徐樨巍,宋文琪,吕　萍,杨永弘,沈叙庄*.儿科患者中分离产金属酶铜绿假单胞菌的分子流行病学研究. 实用儿科临床杂志. 2009,24(10):734-737.核心期刊
38. Xu-zhuang SHEN，Yuan CHENG, Yi WANG, Sang -Jie Yu, Kai-hu Yao, Yong-hong YANG.Macrolide Resistance Mechanisms in Streptococcus pneumoniae Isolates from Chinese Children in Association with Genes of tetM and Integrase of Conjugative Transposons 1545. Microb Drug Resist. 2008,14(2):155-161.SCI
39. Hui DING, Yonghong YANG , Yuan CHENG , Yi WANG, Suyun QIAN Shaozhen FAN, Xuzhuang SHEN* .Five-year Surveillance of Antimicrobial use in Chinese Pediatric Intensive Care Unite. J Trop Pediatrics Advance Access. 2008,54(4):238-242.SCI
40. Aihua WANG, Yonghong YANG, Xuzhuang SHEN*.A Retrospective Study of Nosocomial Infections in a Pediatric Hospital: A Seven-Year Experience at Beijing Children's Hospital. J Trop Pediatrics Advance Access. 2008,54(4):281-282.SCI
41. Hui Ding , Yong-hong YANG , Yuan CHENG, Yi WANG, Sang -Jie Yu, Kai-hu Yao, Shao-zhen Fan, Ai-hua Wang, Lan LIU , Chuan-qing WANG, Jing-hui Zhen, Li WANG, Ling WANG, Xu-zhuang SHEN* .Effectiveness of Intervention for Antibiotic Usage in a Pediatric Intensive Care Unite in China. Pharm World Sci. 2008,30(6):787-793.SCI
42. Wang, Aihua; Yong, Yonghong; Lu, Quan; Wang, Yi; Chen, Yuan; Deng, Li; Ding, Hui; Deng, Qiulian; Wang, Li; Shen, Xuzhuang*.Occurrence of qnr-positive clinical isolates in Klebsiella pneumoniae producing ESBL or AmpC–type β-lactamase from five pediatric hospitals in China. FEMS Microbiology Letters. FEMS Microbiology Letters. 2008,283(1):112-116 .SCI
43. 王爱华 沈叙庄*.新生儿B族链球菌感染分子机制研究进展. 国际儿科学杂志. 2008,35(2):134-136.
44. Hui DING, Yonghong YANG , Yuan CHENG , Yi WANG, Suyun QIAN Shaozhen FAN, Xuzhuang SHEN*.Antimicrobial usage in paediatric intensive care units in China. Acte Pdeatrica. 2008,97:100－104.SCI
45. Wenshuang Zhang, Xuzhuang Shen, Yi Wang, Yuan Chen, Min Huang, Qiyi Zeng , Jinghai Wei, Quan Lu, Gang Wang, Li Deng, Maohuai Fan , Ulf Bergman, Yonghong Yang.Antibiotic use in five children's hospitals during 2002-2006: the impact of antibiotic guidelines issued by the Chinese Ministry of Health. Pharmacoepidemiology and Drug Safety. 2008,Mar;17(3):306-11.SCI
46. 王丽、杨永弘、陆权，王艺，陈沅，邓力，邓秋莲，张泓，王传清，刘岚，徐樨巍，沈叙庄*.儿科常见革兰阴性杆菌耐药性现状分析. 中国感染与化疗杂志. 2008,3(8):187－192.核心期刊
47. 薛冠华、李慎涛、杨永弘、于丽华、王爱华、王冠、岳丽琴、殷国荣、沈叙庄*.B族链球菌表面蛋白C5a肽酶系统及鼻内粘膜免疫的研究. 中华微生物学和免疫学杂志. 2008,28(12):1137-1142.核心期刊
48. Aihua WANG, Yonghong YANG , Min HUANG , Qiyi ZENG , Yuan CHEN , Yi WANG, Wenshuang ZHANG, Quan LU , Li DENG, Lan LIU , Chuanqing WANG , Li WANG, Ling WANG, Xuzhuang SHEN*.Antimicrobial susceptibility of Haemophilus influenzae strains and antibiotics usage patterns in pediatric outpatients: results from a children’s hospital in China (2000-2004). Pediatric Pulmonology . 2008,43(5):457-462.SCI
49. 王冠, 沈叙庄*.粘膜相关淋巴组织的结构特征及粘膜疫苗的研究进展. 中国计划免疫. 2007,13（1）:89-92.EI
50. XZ SHEN, Q LU, L DENG, S YU, H ZHANG, Q DENG, M JIANG, Y HU, KH Yao AND YH YANG.Resistance of Haemophilus influenzae Isolates in Children Under 5 Years Old with Acute Respiratory Infections in China between 2000 and 2002. J Int Med Res. 2007,35(4):433-581.SCI
主编或副主编的著作/译著
重要奖项
1. 细菌对喹诺酮类的质粒介导耐药机制及其耐药性的防治策略 中华医学奖 三等 201111
2. 细菌对喹诺酮类的质粒介导耐药机制及其耐药性的防治策略 教育部科技成果奖 一等 2010
3. 儿科抗菌药物使用与常见细菌耐药监测及耐药机制研究 北京市科技进步奖 三等 2009
4. 儿科抗菌药物使用与常见细菌药监测及耐药机制研究 高等学校科学技术进步奖 二等 2009
5. 儿科抗菌药物使用与常见细菌耐药监测及耐药机制研究 中华医学奖 三等 2009