姓名：任军 性别：男 职称：主任医师、教授 招生院所：附属世纪坛医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：肿瘤学(博) 肿瘤学(硕) 研究方向名称：肿瘤免疫治疗及其转化研究，基因组学指导下的肿瘤精准治疗 电子信箱：renjun9688@yahoo.com


社会任职
1. 北京市肿瘤治疗质量控制与改进中心专家委员会副主任委员
2. 中国医药质量管理协会细胞治疗质量控制与研究专业委员会副主任委员
3. 第七届北京免疫学会理事
个人简历
1. 198309-198907:第四军医大学六年制临床医学系 学习
2. 198909-199709:第四军医大学第一附属医院消化内科 住院医师、主治医师、讲师
3. 199512-199704:(WHO)肿瘤中心、韩国汉城大学肿瘤所 高级访问
4. 199709-199812:第四军医大学第一附属医院消化内科 主治医师、副教授、硕士生导师
5. 199812-200009:第四军医大学第一附属医院肿瘤内科 副主任，主治医师，副教授，硕士生导师
6. 200009-200105:第四军医大学第一附属医院肿瘤科 副主任，主治医师，教授，博士生导师
7. 200105-200109:第四军医大学第一附属医院肿瘤科 主任，主治医师，教授，博士生导师
8. 200109-200606:第四军医大学第一幅是医院肿瘤科 主任，主任医师，教授，博士生导师
9. 200308-200606:北京大学临床肿瘤学院大内科主任（杰出人才引进） 主任，主任医师，教授，博士生导师
10. 200606-201206:北京大学肿瘤临床学院内科 主任，主任医师，教授，博士生导师
11. 200810-:美国杜克（DUKE)大学肿瘤中心 教授（Faculty）
12. 201206-:首都医科大学附属北京世纪坛医院 院长助理，肿瘤中心主任，肿瘤内科主任，肿瘤研究室主任
13. 201306-:肿瘤治疗性疫苗北京市重点实验室 主任
14. 201509-:肿瘤免疫治疗北京市国际科技合作基地 主任
重要学术论文
1. Zhou XN#, Qiao GL#, Ren J#, Wang XL, Wang S, Zhu SY, Yuan YH, Morse MA, Hobeika A, Lyerly HK*.Adoptive immunotherapy with autologous T-cell infusions reduces opioid requirements in advanced cancer patients.. PAIN. 2020,161(1):127-134. .SCI
2. Lv SZ, Wang S, Qiao GL, Wang XL, Zhou XN, Yan FC, Li YP, Wang SY, Morse MA, Hobeika A, Ren J*, Lyerly HK*. Functional CD3+CD8+PD1- T Cell Accumulation and PD-L1 Expression Increases During Tumor Invasion in DCIS of the Breast. . Clin Breast Cancer . 2019,19(5):e617-e623.SCI
3. Zhao Y, Qiao G, Wang X, Song Y, Zhou X, Jiang N, Zhou L, Huang H, Zhao J, Morse MA, Hobeika A, Ren J*, Lyerly HK*. .Combination of DC/CIK adoptive T cell immunotherapy with chemotherapy in advanced non-small-cell lung cancer (NSCLC) patients: a prospective patients' preference-based study (PPPS). Clin Transl Oncol.. 2019,21(6):721-728.SCI
4. Qiao G#, Wang XL#, Zhou L#, Zhou XN, Song Y, Wang S, Zhao L, Morse MA, Hobeika A, Song J, Yi X, Xia X, Ren J*, Lyerly HK*.Autologous dendritic cell-cytokine induced killer cell immunotherapy combined with S-1 plus cisplatin in patients with advanced gastric cancer: A prospective study.. Clin Cancer Res. 2019,25(5):1494-1504.SCI
5. Zhao X, Li YP ,Wang XL, Wu JP, Yuan YH, Lv SZ, Ren J*..Synergistic association of Foxp3+TILs with CCL20 expressions with poor prognosis of primary breast cancer.. Medicine. 2019,98(50):e18403-18414.SCI
6. Zhou L, Ding L, Liu J, Zhang Y, Luo X, Zhao L, Ren J*.Four-and-a-half LIM protein 1 promotes paclitaxel resistance in hepatic carcinoma cells through the regulation of caspase-3 activation. J Cancer Res Ther. 2018,14:767-773.SCI
7. Song QK#, Ren J#*, Zhou XN, Wang XL, Song GH, Hobeika A, Yuan YH, Lyerly H*. .Circulating CD8+CD28- suppressor T cells tied to a poorer prognosis among metastatic breast cancer patients receiving adoptive T cell therapy: a cohort study.. Cytotherapy . 2018,20(1):126-133.SCI
8. Zhou XN, Qiao GL, Wang XL, Song QK, Morse MA, Hobeika A, Gwin WR, Ren J, Lyerly.HKCYP1A1 genetic polymorphism is a promising predictor to improve chemotherapy effects in patients with metastatic breast cancer treated with docetaxel plus thiotepa vs. docetaxel plus capecitabine.. Cancer Chemotherapy and Pharmacology.. 2018,81(2）:365-372. .SCI
9. Cha NE, Han XH, Jia BQ, Liu YH, Wang XL, Gao YW, Ren J*..Structure-Based Design of Peptides against Her2 with Cytotoxicity on colon cancer. . Artif Cells Nanomed Biotechnol.. 2017,45(3):649-654.SCI
10. Zhou L, Zhao LC, Jiang N, Wang XL, Zhou XN, Luo XL, Ren J*..MicroRNA miR-590-5p inhibits breast cancer cell stemness and metastasis by targeting SOX2. 2017;21:87-94.. European Review for Medical and Pharmacological Sciences.. 2017,21:87-94.SCI
11. Zhang YB, Liu Y, Ye YJ, Shen DH, Zhang H, Huang HY, Li S, Wang S, Ren J*..Quantitative proteome analysis of colorectal-cancer-related differential proteins.. J Cancer Res Clin Oncol. 2017,143:233-241.SCI
12. Ren J, Gwin W.R., Zhou XN, Wang XL, Huang HY, Jiang N, Zhou L, Agarwal P., Hobeika A, Morse M.A, Eng K., Lyerly H.K.*.Adaptive T cell responses induced by oncolytic Herpes Simplex Virus - Granulocyte- Macrophage Colony-Stimulating Factor therapy expanded by Dendritic Cell and Cytokine-Induced Killer Cell Adoptive Therapy. . Oncoimmunology.. 2017,6(4):e**(10pages).SCI
13. Qiao GL, Cucchetti A, Li J, Cescon M, Xia Y, Ercolani G, Liu GH, Pinna AD. Shen F*, Li L, Ren J*..Applying of pretreatment extent of disease system in patients with hepatocellular carcinoma after curative partial hepatectomy.. Oncotarget. . 2016,7(21):30408-19..SCI
14. Gao YW, Gao WS, Chen X , Cha NE , Wang XL , Jia XD , Wang BP , Ren M, Ren J*.Enhancing the treatment effect on melanoma by heat shock protein 70-peptide complexes purified from human melanoma cell lines.. Oncology Reports.. 2016,36:1243-1250.SCI
15. Wang XL, Ren J* Zhang J, Yan Y, Jiang N, Yu J, Di LJ, Song GH, Che L, Jia J, Zhou XN, Yang HB, H.K.Lyerly*..Prospective study of cyclophosphamide, thiotepa, carboplatin combined with adoptive DC-CIK followed by metronomic cyclophosphamide therapy as salvage treatment for negative metastatic breast cancers patients (aged<45). . Clinical and Translational Oncology.. 2016,18(1):82-87.SCI
16. Qiao GL, Chen Z, Wang C Ge J, Li L*, Ren J*..Pure Fetal Histology Subtype was Associated with Better Prognosis of Children with Hepatoblastoma: A Chinese Population-based Study. . J Gastroenterol Hepatol.. 2016,31(3):621-627..SCI
17. 黄红艳、王小利、周心娜、张彦斌、李莎、任军*.两种方法分离建议细胞用于高通量测序TCR组库分析的比较. . 中华保健医学杂志. 2015,17（3）:215-218.核心期刊
18. Qing-Kun Song*, Jun Ren*#,Xin-Na Zhou, Xiao-Li Wang, Guo-Hong Song, Li-Jun Di, Jing Yu, Amy Hobeika, Mike Mouse, Yan-Hua Yuan,Hua-Bing Yang, Herbert Kim Lyerly#..The prognostic value of peripheral CD4+CD25+ T lymphocytes among early stage and triple negative breast cancer patients receiving dendritic cells-cytokine induced killer cells infusion. Oncotarget . 2015,6(380):41350-41359.SCI
19. Zhou XN, Wang XL, Song QK, Yang HB, Zhu XS, Yu J, Song GH, Di LJ, Ren J*, Shao H*, Herbert K Lyerly. .Transformation of alkylating regimen of thiotepa into tepa determines the disease progression through GSTP1 gene polymorphism for metastatic breast cancer patients receiving thiotepa containing salvage chemotherapy.. Int J Clin Pharmacol Ther. . 2015,53(11):914-22.SCI
20. Zhou XN#,Yu J#, Wang WM, Song GH, Wang XL, Ren J*, Di LJ*, Wang XH*..A Phase I Dose-Escalation Study of the Domestic Trastuzumab in Chinese Metastasis Breast Cancer Patients. Spriger Plus. 2015,4:833.
21. Maria Fawzy, Zeba Aziz, Reena Nair, C S Pramesh, Vani Parmar, Purvish Parikh, Rozmin Jamal, Azizunissa Irumnaz, Jun Ren, Martin Stockler, Amy P Abernethy, Herbert K Lyerly*. Regional vriation in identified cancer care needs of early career oncologist in China, India and Pakistan. The Oncologist. . 2015,20(5):562-538.SCI
22. Zhao YJ, Jiang N, Song QK, Wu JP, Song YG, Zhang HM, Chen F, Zhou L, Wang XL, Zhou XN, Yang HB, Ren J,* Herbert K Lyerly*..Continuous DC-CIK infusions sufficiently restore CD8+cellular immunity, physical activity and improve clinical efficacy in advanced cancers patients failed and untolerated to conventional anti-cancer treatments. . APJCP. 2015,16(6):2419-2423.SCI
23. Lu M, Zhou L, Zheng XH, Quan Y, Wang XL, Zhou XN, Ren J* .A novel molecular marker of breast cancer stem cells identified by cell-SELEX method.. Cancer Biomark. 2015,15:169-176.SCI
24. 黄红艳、张彦斌、王小利、周心娜、李莎、王嫚娜、任军*.靶向敲低核蛋白1抑制HepG2肝癌细胞增殖及迁移. 细胞与分子免疫学杂志. 2015,31（6） :782-788. .核心期刊
25. Song QK#, Wang XL#, Zhou XN, Yang HB, Li YC, Wu JP, Ren J*, Herbert K Lyerly*. Breast Cancer Challenge and Screening in China: A lesson from the sporadic data and new directions advocates.. The Oncologist . 2015,20(7):773-779..SCI
26. Hongyan Huang, Ang Chen, Ting Wang, Manna Wang, Xiangkai Ning, Meifang He, Yazhuo Hu, Long Yuan, Shichong Li, Qiwei Wang, Hong Liu, Zhaolie Chen, Jun Ren*, Qiang Sun*.Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining.. Oncotarget . 2015,6(24):20278-87.:20278-2087..SCI
27. 任军.肿瘤微环境及免疫调节系列研究指导乳腺癌精确治疗的临床实践... 肿瘤防治研究. 2014,41(11 ):23-26..核心期刊
28. Zhu XS, Yu HJ, He BX, Zhou XN, Jiang N, Ni, Zhang HM, Wang XL, Ren J*. .Mouse Flk-1+Sca-1- Mesenchymal Stem Cells: Functional Plasticity In Vitro and Immunoregulation In Vivo. . Transplantation. 2014,97(5):509-517.SCI
29. Jiang N, Zhu XS, Zhang HM, Wang XL, Zhou XN, Gu JZ, Chen BA, Ren J*. .The relationship between methylenetetrahydrofolate reductase polymorphism and hematological malignancy.. Clin. Lab. 2014,60:767-774.SCI
30. Song QK, Christiani DC, Wang XR, Ren J*. .The global contribution of outdoor air pollution to the incidence, prevalence, mortality and hospital admission for chronic obstructive pulmonary disease: a systematic review and meta-analysis.. Int J Environ Res Public Health. 2014,11(11):11822-11832..SCI
31. 任军，黄红艳.靶向免疫检查点的肿瘤免疫治疗现状与趋势.. 中国肿瘤临床. 2014,41(7):415-417.核心期刊
32. 任军，黄红艳.中国肿瘤细胞免疫治疗的现状与趋势. 转化医学研究（电子版. 2014,4(3:63-69..核心期刊
33. Zhu XS, He BX, Zhou XN, Ren J*.The comparison of effects of human adipose and bone marrow mesenchymal stem cells on T lymphocyte. Cell biology international. 2013,37(1):11-18.SCI
34. Zhu Xishan , Zhou Xinna, He baoxin, Ren Jun*.Impaired immuno-modulatory function of Chronic Myeloid Leukemia cancer stem cells and the possible mechnism involved in it. . Cancer immunology and immunotherapy. 2013,62(4):689-703.SCI
35. Ren J, Di LJ, Song GH, Yu J, Jia J, Zhu YL, Yan Y, Jiang HF, Liang X, Che L, Zhang J, Wan FL, Wang XL, Zhou XN, Lyerly H..Selections of appropriate regimen of high-dose chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells improved progression free and overall survival in patients with metastatic breast cancer: reagument of such contentious therapeutic preferences.. Clinical and Translational Oncology. 2013,15(10):780-788.SCI
36. 任军. 当前急需培养研究型临床肿瘤医学科学家.医学争鸣.2013;4(4):14-16. 医学争鸣. 2013,4(4):14-16.核心期刊
37. Song GH, Wang XL, Jia J. Yuan YH, Wan FL, Zhou XN, Yang HB, Ren J.*, Gu JZ, Lyerly HK.*. Elevated Level of Peripheral CD8+CD28- T Lymphocytes Are an Independent Predictor of Progression-Free Survival in Patients with Metastatic Breast Cancer during the course of chemotherapy. . Cancer Immuno Immunotherapy.. 2013,62:1123-1130.SCI
38. Dong NN, Yu J, Wang CY, Zheng XH, Wang Z, Di LJ, Song GH, Zhu BD, Che L, Jia J, Jiang HF, Zhou XN, Wang XL, Ren J*..Pharmacogenetic assessment of clinical outcome in patients with metastatic breast cancer treated with docetaxel plus capecitabine.. Journal of Cancer Research and Clinical Oncology. 2012,138::1197–1203.SCI
39. Che L, Yuan YH, Jia J, Ren J*.Activation of sonic hedgehog signaling pathway is an independent potential prognosis predictor in human hepatocellular carcinoma patients. Chin J Cancer Res . 2012,24(4):323-331.SCI
40. Wang Z, Liang X, Yu J, Zheng XH, Zhu YL, Yan Y, Dong NN, Di LJ, Song GH, Zhou XN, Wang XL, Yang HB, Ren J*.Nongenetic risk factors and predicting efficacy for docetaxel-DILI among metastatic breast cancer patients. . Journal of Gastroenterology and Hepatology. 2012,27:1348–1352.SCI
41. Cao BS, Jia J, Ma LW ,Di LJ, Song GH, Yuan YH, Ma B, Zhu YL, Yu J, Wang XL, Zhou XN, H Kim Lyerly, Ren J..Recombinant human endostatin can suppress proangiogenesis induced by side population (SP) cells from non-small lung cancer cell lines.. Clinical and Translational Oncology. 2012,14(8):575-585.SCI
42. Ma B, Jiang HF, Jia J, Di LJ, Song GH, Yu J, Zhu YL, Lu ZH, Wang XL, Zhou XN, Ren J.*.Murine bone marrow stromal cells pulsed with homologous tumor derived exosomes inhibit proliferation of liver cancer cells. Clinical and Translational Oncology. 2012,14(10):764-773.SCI
43. Di LJ, Zhu YL, Jia J, Yu J, Song GH, Zhang J, Che L, Yang HB, Han Y, Ma B, Zhang CR, Yuan YH, You MN, Wan FL, Wang XL, Zhou XN , Ren J* .Clinical safety of induced CTL transfusion through recombinant adeno-associated virus transfected dendritic cells vaccination in Chinese cancer patients.. Clinical and Translational Oncology. 2012,14(9）:675-681.SCI
44. Zhu YL, Song GH, Liu DQ, Zhang X, Liu KF, Zang AH, Cheng Y, Cao GC, Liang J,Ma XZ, Ding X, Wang B,Li WL, Hu ZW, Feng G, Huang JJ, Zheng X, JiaoSC, Yu R, Ren J*. .Multicenter clinical study for evaluation of efficacy and safety of transdermal fentanyl matrix patch in treatment of moderate to severe cancer pain in 474 chinese cancer patients.. Chin J Cancer Res. . 2011,23(4):245-253.SCI
45. Zhang L#, Ren J#, Pan K, Ma J, Li J, Shen L, Zhang X, Li J, Fan D, Gail M, You W. Detection of gastric carcinoma-associated MG7-Ag by serum immuno-PCR assay in a high-risk Chinese population, with implication for screening.. Int J Cancer.. 2010,126(2):469-473.SCI
46. Di Lijun, Ren J*, Yan Ying, Wan Fengling, Song Guohong, Yu Jing.Long-term efficacy and safety of pamidronate disodium in treatment of bone metastases in breast cancer.. Chin. J. Cancer Res.. 2009,21(2):109-114 .SCI
47. Ren J#, Jia J#, Zhang HM, Zhang LW, Ma B, Jiang HF, Di LJ, Song GH, Yu J,.Dendritic Cells Pulsed With Alpha-Fetoprotein and Mutant P53Fused Gene Induce Bi-targeted CTL Response against Hepatic Carcinoma.. Cancer Sci. 2008,99(7):1420-1426.SCI
主编或副主编的著作/译著
1. 《肿瘤免疫治疗细胞制备操作规程及临床治疗进展》,主编,人民军医出版社,201506
重要奖项