- 闫巧娟导师简介 -
基本信息
目前指导研究生
在籍
- 博士研究生2人 （其中 2013级:1 2014级:1） 硕士研究生6人 （其中 2014级:2 2015级:4）
不在籍
- 博士研究生4人 （其中 2010级:2 2012级:1 2013级:1） 硕士研究生13人 （其中 2006级:1 2007级:2 2008级:2 2009级:1 2010级:3 2011级:2 2012级:2）
个人简历
博士、教授、博士生导师。1997年参加工作，2000年5～7月在日本畜产试验场进行合作研究。2003年9月破格晋升为副教授。2009年底晋升教授。教育部新世纪优秀人才支持计划入选者。
主要研究方向：天然产物研究与开发、生物质资源开发与利用等。
科研成果获奖情况：主要参与完成9项国家级课题，主持国家自然科学基金、863计划等省部级以上课题5项，获得国家科技进步二等奖及教育部科技进步一等奖各一项。
论文及专著：近五年发表科技论文50余篇，其中SCI收录30篇。参编专业著作2部。
专利情况：近五年获得国家发明专利8项，另外申报国家发明专利5项，均已公开。
遴选学科专业
不公开
论文与专著
近期有关代表性论文（25篇）：
1. Katrolia Pritiriti, Huiyong Jia, Qiaojuan Yan, Shuang Chunlei Song , Zhengqiang Jiang, Haibo Xu. 2012.Characterization of a protease-resistant α-galactosidase from the thermophilic fungus Rhizomucor miehei and its application in removal of raffinose family oligosaccharides. Bioresource Technology, 110(4): 578-586.
2. Qiaojuan Yan, Luo Tang, Shaoqing Yang,Shuping Zhang, Zhengqiang Jiang. 2012. Purification and characterization of a novel thermostable α-L-arabinofuranosidase (α-L-AFase) from Chaetomium sp. Process Biochemistry, 47(3), 472-478.
3. Linhua Huang, Qiaojuan Yan,Narasimaha Kumar Kopparapu , Zhengqiang Jiang, Yan Sun. 2012. Astragalus membranaceus lectin (AML) induces caspase-dependent apoptosis in human leukemia cells. Cell Proliferation, 45(1): 15-21.
4. Narasimaha Kumar Kopparapu, Peng Zhou, Shuping Zhang, Qiaojuan Yan, Zhengqiang Jiang, Zhuqing Liu.2012. Purification and characterization of a novel chitinase gene from Paecilomyces thermophila expressed in Escherichia coli. Carbohydrate Research, 347(1): 155-160.
5. Katrolia Priti, Peng Zhou, Pan Zhang, Qiaojuan Yan, Yinan Li, Zhengqiang Jiang, Haibo Xu.2012. High level expression of a novel β-mannanase from Chaetomium sp. exhibiting efficient mannan hydrolysis. Carbohydrate Polymers, 87(1): 480-490.
6. Yanbin Tang, Shaoqing Yang, Qiaojuan Yan, Jian Cui, Zhengqiang Jiang.2012. Purification and Characterization of a Novel β-1,3–1,4-Glucanase (Lichenase) from Thermophilic Rhizomucor miehei with High Specific Activity and Its Gene Sequence. Journal of Agricultural and Food Chemistry, 60(9): 2354-2361.
7. Huiyong Jia, Yinan Li, Yuchun Liu, Qiaojuan Yan, Shaoqing Yang, Zhengqiang Jiang. 2012. Engineering a thermostable β-1,3-1,4-glucanase from Paecilomyces thermophilat improve catalytic efficiency at acidic pH. Journal of Biotechnology, 159(1-2):50-55.
8. Huiyong Jia, Guangsen Fan, Qiaojuan Yan,Yuchun Liu, Ye Yan, Zhengqiang Jiang. 2012. High-level expression of a hyperthermostable Thermotoga maritima xylanase in Pichia pastoris by codon optimization. Journal of Molecular Catalysis B: Enzymatic,78:72-77.
9. QiaojuanYan, ChengweiHua, ShaoqingYang, Yinan Li, Zhengqiang Jiang.2012. High level expression of extracellular secretion of a β-glucosidase gene (PtBglu3) from Paecilomyces thermophila in Pichia pastoris. Protein Expression and Puri?cation,84;64-72.
10. Chao Teng, Huiyong Jia, Qiaojuan Yan, Peng Zhou, Zhengqiang Jiang. 2011. High-level expression of extracellular secretion of a β-xylosidase gene from Paecilomyces thermophila in Escherichia coli. Bioresource Technology, 102(2): 1822-1830.
11. Narasimaha Kumar Kopparapu, Zhuqing Liu,Qiaojuan Yan, Zhengqiang Jiang,Shuping Zhang. 2011. A novel thermostable chitinase (PJC) from pomegranate (Punica granatum) juice. Food Chemistry, 127(4): 1569-1575.
12. Peng Zhou, Huifang Zhu, Qiaojuan Yan, Katrolia Priti,Zhengqiang Jiang. 2011. Purification and properties of a Psychrotrophic Trichoderma sp. xylanase and its gene sequence. Applied Biochemistry and Biotechnology, 164(6): 944-956.
13. Narasimaha Kumar Kopparapu , Zhuqing Liu, Fan Fei, Qiaojuan Yan, Zhengqiang Jiang. 2011. Purification and characterization of a chitinase (sAMC) with antifungal activity from seeds of Astragalus membranaceus. Process Biochemistry, 46(6): 1370-1374.
14. Katrolia Priti, Qiaojuan Yan, Huiyong Jia, Yinan Li, Zhengqiang Jiang, Chunlei Song. 2011. Molecular cloning and high-level expression of a β-galactosidase gene from Paecilomyces aerugineus in Pichia pastoris. Journal of Molecular Catalysis B-Enzymatic, 69(3-4): 112-119.
15. Katrolia Priti,Min Zhang, Qiaojuan Yan, Zhengqiang Jiang, Chunlei Song, Lite Li. 2011. Characterisation of a thermostable family 42 β-galactosidase (BgalC) family from Thermotoga maritima showing efficient lactose hydrolysis. Food Chemistry, 125(2): 614-621.
16. Chao Teng, Qiaojuan Yan, Zhengqiang Jiang, Guangsen Fan, Bo Shi. 2010. Production of xylooligosaccharides from the steam explosion liquor of corncobs coupled with enzymatic hydrolysis using a thermostable xylanase. Bioresource Technology, 101(19): 7679-7682.
17. Zhengqiang Jiang, Qianqian Cong, Qiaojuan Yan, Narasimaha Kumar Kopparapu, Xuedan Du.2010. Characterisation of a thermostable xylanase from Chaetomium sp. and its application in Chinese steamed bread. Food Chemistry, 120(2): 457-462.
18. Yang Guo, Qiaojuan Yan, Zhengqiang Jiang, Chao Teng, Xinlei Wang.2010. Efficient production of lactic acid from sucrose and corncob hydrolysate by a newly isolated Rhizopus oryzae GY18. Journal of Industrial Microbiology & Biotechnology, 37(11): 1137-1143.
19. Qiaojuan Yan, Lifen Zhu, Narasimaha Kumar Kopparapu, Zhengqiang Jiang, Linhua Huang. 2010. Characterisation of a novel monomeric lectin (AML) from Astragalus membranaceus with anti-proliferative activity. Food Chemistry, 122(3): 589-595.
20. Chengwei Hua, Qiaojuan Yan, Zhengqiang Jiang, Yinan Li, Katrolia Priti. 2010. High-level expression of a specific β-1,3-1,4-glucanase from the thermophilic fungus Paecilomyces thermophila in Pichia pastoris. Applied Microbiology and Biotechnology,88(2): 509-518.
21. Shaoqing Yang, Lijun Wang, Qiaojuan Yan, Zhengqiang Jiang, Lite Li. 2009. Hydrolysis of soybean isoflavone glycoside s by a thermostable β-glucosidase from Paecilomyces thermophila. Food Chemistry, 115(4): 1247-1252.
22. Qiaojuan Yan, Shanshan Hao, Zhengqiang Jiang, Qian Zhai, Weiwei Chen. 2009. Properties of a xylanase from Streptomyces matensis being suitable for xylooligosaccharides production. Journal of Molecular Catalysis B-Enzymatic, 58(1-4): 72-77.
23. Qiaojuan Yan, Aimin Wu, Zhengqiang Jiang, Luo Tang, Bo Shi. 2009. Enhanced production of a thermostable mannanase by immobilized cells of Bacillus subtilis on various membranes. World Journal of Microbiology & Biotechnology, 25(6): 1057-1063.
24. Qiaojuan Yan, Yanxia Li , Zhengqiang Jiang, Yan Sun, Lifen Zhu, Zufeng Ding.2009. Antiproliferation and apoptosis of human tumor cell lines by a lectin (AMML) of Astragalus mongholicus. Phytomedicine, 16(6-7): 586-593.
25. Qiaojuan Yan, Lan Wang, Zhengqiang Jiang, Shaoqing Yang, Huifang Zhu, Lite Li. 2008. A xylose-tolerant β-xylosidase from Paecilomyces thermophila: Characterization and its co-action with the endogenous xylanase. Bioresource Technology, 99(13): 5402-5410.
近五年承担的主要项目
2001～2004年参与完成了国家“十五”攻关课题“2002BA514A-12生物饲料添加剂研究与开发”。作为其子课题“2002BA514A-12-3植物来源免疫增强剂研究与开发”的副主持。
2006~2007.6主持北京市自然基金预探索项目“**黄芪中蛋白质成分的生物活性和利用价值”。
2006年开始作为国家自然基金“**黄芪中生物活性蛋白的纯化和性质研究”的主持人对黄芪中的活性蛋白成分进行较为系统的研究。
2008年入选教育部新世纪人才支持计划。
另外，参与完成国家“十五”攻关课题“嗜热真菌耐热木聚糖酶的高产菌株选育、研发和应用”于2005年顺利通过了教育部组织的专家鉴定，整体达到国际先进水平。
目前正在承担的主要科研任务
新世纪人才支持计划
教育部
嗜热真菌耐热β-1,3-1,4-葡聚糖酶基因的克隆、高效分泌表达和作用机制
国家自然基金
食品酶发酵与制剂化关键技术
863
玉米芯高效转化功能性糖技术应用示范
农业科技转化资金
新型耐热酸性β-甘露聚糖酶的发掘、分子改造及其作用机理
国家自然基金
低聚木糖和低聚半乳糖高效清洁生产技术
横向
利用农业废弃物高效生产低聚木糖的技术开发
横向
承担的教学工作
主讲《农业纤维质资源高效利用技术》等2门课程。
