- 苟克勉导师简介 -
基本信息
目前指导研究生
在籍
- 博士研究生3人 (其中 2014级:1 2015级:2) 硕士研究生1人 (其中 2014级:1)
不在籍
- 博士研究生6人 (其中 2005级:1 2006级:2 2007级:1 2010级:1 2011级:1) 硕士研究生3人 (其中 2004级:1 2008级:1 2011级:1)
个人简历
1988至1997年,北京农业大学本科和研究生,1997夏季获得博士学位。1997至1999年,在军事医学科学院生物工程研究所、和中国科学院发育生物学研究所从事博士后研究工作;1999年起,在中国农业大学生物学院,农业生物技术国家重点实验室工作。期间,先后在新西兰AgResearch研究所(2000年)和澳大利亚SARDI研究所从事绵羊和奶牛的体细胞克隆和超数卵泡诱导发育JIVET技术的研究、澳大利亚Monash Institute of Reproduction & Development从事大鼠体细胞核移植研究工作(2002-2003)、英国牛津大学Functional Genetics Unit (2011-2012)从事CTP合成酶功能及新型细胞器cytoophidium结构与功能的研究。
遴选学科专业
不公开
论文与专著
1.Ke-Mian Gou#, Chia-Chun Chang#, Qing-Ji Shen, Li-Ying Sung, Ji-Long Liu*. CTP synthase forms cytoophidia in the cytoplasm and nucleus. Experimental Cell Research, 2014, 323(1):242-53. doi: 10.1016/j.yexcr.2014.01.029.2.Bo-Wen Yan, Yao-Feng Zhao, Wen-Guang Cao, Ning Li, Ke-Mian Gou*. Mechanism of Random Integration of Foreign DNA in Transgenic Mice. Transgenic Research, 2013, 22(5):983-992. DOI: 10.1007/s11248-013-9701-z.3.Xue-Jing Zhang, Jian-Hua Li, Jia-Li Liu, Hao-Shu Luo, Ke-Mian Gou, Sheng Cui*. Prostaglandin F2α upregulates Slit/Robo expression in mouse corpus luteum during luteolysis. Journal of Endocrinology. 2013, 218(3): 299-310.4.Yong-Gang Chen, Bo-Wen Yan, Wen-Guang Cao, Shu-Yu Ma, Ke-Mian Gou*. Decreased saturated fatty acids, total cholesterol and LDL-C in sdd17 mice. Frontiers of Bioscience (Landmark Edition), 2013, 18: 901-908.5.WANG Ping, WEI ZhiGuo, YAN BoWen, HUANG Tian, GOU KeMian, DAI YunPing, ZHENG Min, WANG MeiLi, CHENG XueQian, WANG XiFeng, XU Chen, SUN Yi*. Establishment of a transgenic mouse model with liver-specific expression of secretory immunoglobulin D. SCIENCE CHINA Life Sciences, 2012, 55(3): 219-227. doi:10.1007/s11427-012-4301-36.Lin W, Rahman NA, Lin J, Zhang H, Gou KM, Yu WP, Zhu DH, Li N, Huhtaniemi I & Li XD*. Molecular mechanisms of bladder outlet obstruction in transgenic male mice overexpressing aromatase (Cyp19a1). The American Journal of Pathology. 2011, 178: 1233-1244.7.Yan BW, Li DF, Gou KM*. Homologous illegitimate random integration of foreign DNA into the X chromosome of a transgenic mouse line. BMC Molecular Biology. 2010, 11:58.8.Wu ZF, Li DF, Gou KM*. Overexpression of stearoyl-CoA desaturase-1 results in an increase of conjugated linoleic acid (CLA) and n-7 fatty acids in 293 cells. Biochemical and Biophysical Research Communications. 2010; 398: 473-476.9.Chen YG, Zhang M, Gou KM*. SDD17 desaturase can convert arachidonic acid to eicosapentaenoic acid in mammalian cells. Biochemical and Biophysical Research Communications. 2010; 394: 158-162.10.Li HY, Pan LX, Gou KM*. Depletion of Ribosomal protein L8 impairs the Drosophila development associated with apoptosis. Science in China Series C: Life Sciences. 2010, 53(9): 1092-1097.11.Chen Q, Liu Q, Wu ZF, Wang ZY, Gou KM*. Generation of fad2 transgenic mice that produce omega-6 fatty acids. Science in China Series C-Life Sciences. 2009; 52: 1048-1054.12.Yao H, Li BX, Wang SF, Kou ZH, Zhang Y, Gao SR, Gou KM*. Genome-wide and gene specific paternal demethylation in androgenetic embryos. Frontiers in Bioscience. 2009; 14: 3884-3891.13.Gou KM, Guan H, Bai JH, Cui XH, Wu ZF, Yan FX, An XR. Field evaluation of juvenile in vitro embryo transfer (JIVET) in sheep. Animal Reproduction Science. 2009; 112: 316-324.14.Wang Y, Yao H, An XR, Chen YF, Gou KM*. Gene transcription of mouse telomerase catalytic subunit in preimplantation embryos. Progress in Biochemistry and Biophysics, 2005; 32: 282-287.15.Gou KM, An XR, Guan H, Yang XY, Hou J, Zhu SE, Zeng SM, Tian JH, Chen YF. Transgenic twin lambs cloned by granulosa cells. Cloning and Stem Cells. 2003; 5: 71-78.16.An XR*, Gou KM*, Zhu S, Guan H, Hou J, Lin AX, Zeng SM, Tian JH, Chen YF. Cloned calves produced by nuclear transfer from cultured cumulus cells. Science in China Series C-Life Sciences. 2002; 45: 201-210.17.An XR, Gou KM*, Chen YF. Production of transgenic blastocyst of sheep by somatic cell cloning. Chinese Science Bulletin, 2001; 46: 1630-1634.18.Gou KM, Shang LJ, An XR, Deng JX, Chen YF, Huang PT. Effect of monoclonal antibody to bull sperm sp18 on murine fertilization and embryos development. Chinese Science Bulletin, 1999; 44: 236-240.19.Gou KM, Shang LJ, An XR, Lin AX, Ren LM, Chen YF. Extraction of sp18 family membrane proteins on posterior head of bull sperm and the effect of anti-sp18 IgG on sperm motility and murine in vitro fertilization. Animal Biotechnology, 1998; 9: 149-153.
近五年承担的主要项目
转基因生物新品种培育重大专项子课题。
承担的教学工作
主讲课程:
转基因动物与克隆动物 (研究生) ;发育生物学专题(研究生)
动物生殖生物学(本科生) ;动物生理学实验(本科生)