- 周磊导师简介 -
基本信息
姓名*周磊
姓名拼音Zhou Lei
教师号不公开
出生日期不公开
性别男
所属院系动物医学院
国籍中国
民族汉族籍贯不公开参加何党派不公开加入党派时间不公开最高学历博士研究生最高学位博士毕业学校中国农业大学毕业时间2010-06-22最高学位授予国别中国最高学位授予单位中国农业大学最高学位授予专业2010最高学位授予时间2010-06-22外语语种英语外语熟练程度熟练来校时间不公开参加工作时间不公开在职状态不公开教师来源不公开职称副教授职称评聘时间不公开职务无任职时间不公开证件类型不公开证件号码不公开办公电话**家庭电话不公开手机不公开传 真不公开通信地址海淀圆明园西路2号动医动科大楼325室邮政编码100193电子邮箱leosj@cau.edu.cn教师主页导师类型硕导是否外聘否兼职聘期起始日期兼职聘期终止日期兼职所在原单位是否在外单位担任兼职导师不公开主要兼职单位名称不公开专家类别从事学科专业1兽医学090602-预防兽医学从事学科专业2兽医学0906Z1-兽医生物医学首任导师时间2014-01研究方向1动物分子病毒学与免疫学研究方向2研究方向3研究方向4备注

目前指导研究生
在籍

博士研究生 0人 硕士研究生3人 （其中 2014级:1 2015级:2）
不在籍
博士研究生 0人 硕士研究生 0人
个人简历

遴选学科专业
不公开
论文与专著
Publications:
1.Li Y^co,Zhou Lei^co, Zhang JL, Ge XN, Zhou R, Zheng HG, Geng G, Guo X, Yang HC*. 2014. NSP9 and NSP10 Contribute to the Fatal Virulence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Emerging in China. PLoS pathogens. 10, e**.

2.Li Wang^co, Zhou Lei^co, Han Zhang, Yan Li, Xinna Ge, Xin Guo, Kangzhen Yu, Hanchun Yang, Interactome Profile of the Host Cellular Proteins and the Nonstructural Protein 2 of Porcine Reproductive and Respiratory Syndrome Virus. PLoS ONE 9(6): e99176. doi:10.1371/journal.pone.**

3.Zhou Lei, Xiaorong Yang, Yuan Tian, et al., Genetic Diversity Analysis of Genotype 2 Porcine Reproductive and Respiratory Syndrome Viruses Emerging in Recent Years in China. BioMed Research International, vol. 2014, Article ID 748068, 13 pages, 2014. doi:10.1155/2014/748068
4.Zhou Lei, Ni Y-Y, Pi?eyro P, Cossaboom CM, Subramaniam S, et al. (2013) Broadening the Heterologous Cross-Neutralizing Antibody Inducing Ability of Porcine Reproductive and Respiratory Syndrome Virus by Breeding the GP4 or M genes. PLoS ONE 8(6): e66645. doi:10.1371/journal.pone.**
5.Zhou Lei, Ni, Y.-Y., Pi?eyro, P., Sanford, B., Cossaboom, C., Dryman, B., Huang, Y.-W., Cao, D.-J., Meng, X.-J., 2012. DNA shuffling of the GP3 genes of porcine reproductive and respiratory syndrome virus (PRRSV) produces a chimeric virus with an improved cross-neutralizing ability against a heterologous PRRSV strain. Virology434, 96-109.
6.Zhou, Lei, Yang, H., 2010. Porcine reproductive and respiratory syndrome in China. Virus research154, 31-37.
7.Zhou, Leico, Chen, Sco., Zhang, J., Zeng, J., Guo, X., Ge, X., Zhang, D., Yang, H., 2009a. Molecular variation analysis of porcine reproductive and respiratory syndrome virus in China. Virus research145, 97-105.
8.Zhou, Leico, Zhang, J. co, Zeng, J., Yin, S., Li, Y., Zheng, L., Guo, X., Ge, X., Yang, H., 2009b. The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence. Journal of virology83, 5156-5167.
9.Gerber, P., O'Neill, K., Owolodun, O., Wang, C., Harmon, K., Zhang, J., Halbur, P., Zhou, Lei, Meng, X.-J., Opriessnig, T., 2013. Comparison of Commercial Real-Time Reverse Transcription-PCR Assays for Reliable, Early, and Rapid Detection of Heterologous Strains of Porcine Reproductive and Respiratory Syndrome Virus in Experimentally Infected or Noninfected Boars by Use of Different Sample Types. Journal of clinical microbiology51, 547-556.
10.Ni, Y.-Y., Opriessnig, T., Zhou Lei, Cao, D., Huang, Y.-W., Halbur, P., Meng, X.-J., 2013. Attenuation of porcine reproductive and respiratory syndrome virus by molecular breeding of virus envelope genes from genetically divergent strains. Journal of virology87, 304-313.
11.Opriessnig, T., O'Neill, K., Gerber, P., de Castro, A.M., Gimenéz-Lirola, L., Beach, N., Zhou, Lei, Meng, X.-J., Wang, C., Halbur, P., 2013. A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection. Vaccine31, 487-494.
12.Gao, Y., Kou, Q., Ge, X., Zhou, Lei, Guo, X., Yang, H., 2012. Phylogenetic analysis of porcine epidemic diarrhea virus field strains prevailing recently in China. Arch Virol.
13.Liu, Q., Qin, Y., Zhou, Lei, Kou, Q., Guo, X., Ge, X., Yang, H., Hu, H., 2012. Autophagy sustains the replication of porcine reproductive and respiratory virus in host cells. Virology429, 136-147.
14.Wang, L., He, Q., Gao, Y., Guo, X., Ge, X., Zhou, Lei, Yang, H., 2012. Interaction of cellular poly(C)-binding protein 2 with nonstructural protein 1β is beneficial to Chinese highly pathogenic porcine reproductive and respiratory syndrome virus replication. Virus research169, 222-230.
15.Liu, D., Zhou, R., Zhang, J., Zhou, L., Jiang, Q., Guo, X., Ge, X., Yang, H., 2011. Recombination analyses between two strains of porcine reproductive and respiratory syndrome virus in vivo. Virus research155, 473-486.
16.Pan M, Yang X, Du J, Zhou Lei, Ge X, Guo X, Liu J, Zhang D, Yang H. 2011.Recovery of duck hepatitis A virus 3 from a stable full-length infectious cDNA clone. Virus Research 160(1-2), 439-43.
17.Pan M, Yang X, Zhou Lei, Ge X, Guo X, Liu J, Zhang D, Yang H. 2011.Duck Hepatitis A Virus Possesses a Distinct Type IV Internal Ribosome Entry Site Element of Picornavirus.Journal of Virology 86(2), 1129-44.


International Conference:

1.Lei Zhou, Hanchun Yang. “Present Status of PRRSV Diversity in China”. PRRSCon Meeting , Ghent Belgium. 15-16 May,2014.
2.Lei Zhou, Xingchen Wang, Hanchun Yang. “Nsp9 and Nsp10 contribute to the pathogenicity of genotype 1 PRRSV Isolated in China” PRRSCon Meeting , Ghent Belgium. 15-16 May,2014.
3.Lei Zhou, Yan-Yan Ni, Pablo Pin ? eyro1, Caitlin M. Cossaboom, Sakthivel Subramaniam, Brenton J. Sanford, Barbara A. Dryman, Yao-Wei Huang, Xiang-Jin Meng Broadening the Heterologous Cross-Neutralizing Antibody Inducing Ability of Porcine Reproductive and Respiratory Syndrome Virus by Breeding the GP4 or M genes Confference of Reseachers Work on Animal Diseases， Chicago IL, United States. December 8-10, 2013. Oral presenter.
4.Lei Zhou, Xingchen Wang, Hanchun Yang. “Genomic characterization and pathogenicity of a genotype 1 PRRSV Isolated in China” PRRSCon Meeting , Loti, Italy. 21-22 November, 2013.
5.Lei Zhou, Ni, Y.-Y., Pi?eyro, P., Sanford, B., Cossaboom, C., Dryman, B., Huang, Y.-W., Cao, D.-J., Meng, X.-J.. DNA shuffling of the GP3 genes of porcine reproductive and respiratory syndrome virus (PRRSV) produces a chimeric virus with an improved cross-neutralizing ability against a heterologous PRRSV strain. No .157. Confference of Reseachers Work on Animal Diseases， Chicago IL, United States. December 3-4, 2012. Oral presenter.
6.Dan Liu, Rong Zhou, Lei Zhou, XinGuo, XinnaGe, Hanchun Yang. The recombination between two strains of PRRSV in vivo results in the generation of recombinant virus with higher pathogenicity. P67, International PRRS Symposium, Chicago IL, United States. 2-3 ,December, 2011. Oral presenter.
7.Zhou Lei, Zhang, J., Zeng, J., Yin, S., Li, Y., Zheng, L., Guo, X., Ge, X., Yang, H., 2009b. The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence. New generation researchers in pig viral diseases: building bridges from labs to policy and the farm, Madrid, Spain July, 2011. Oral presenter


近五年承担的主要项目
科研项目：
2014年不同致病性PRRSV毒株复制保真性分析[中国农业大学基础科研业务费]
2014年企业横向合作项目
2014年-2015年猪繁殖与呼吸综合征病毒Nsp9影响病毒复制保真性的作用分析[国家自然科学基金青年项目**]
2014年-2015年基于microRNA的猪繁殖与呼吸综合征病毒高致病性毒株致弱研究[大北农青年研究基金]
2013年-2017年基于猪繁殖与呼吸综合征病毒RdRP的抗病毒研究[高等学校全国优秀博士论文作者专项资金资助项目]
2013年-2014年HP-PRRSV感染对PAM microRNA转录谱的影响分析[家畜疫病病原生物学国家重点实验室开放基金课题]
2013年-2014年勃林格殷格翰PRRSV年度研究基金
2010年-2011年ORF1b编码区与高致病性PRRSV 毒力相关氨基酸位点分析 [中国农业大学基础科研业务费]

承担的教学工作
《兽医微生物学》 动物医学院 本科生

《兽医免疫学实验》动物医学院 本科生

《预防兽医学专业Seminar》预防兽医学 博士研究生

《分子病原学》 中国农业科学院研究生院硕士研究生