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中国医学科学院输血研究所导师教师师资介绍简介-何苗—副研究员

本站小编 Free考研考试/2020-05-10


何苗,男,汉族。2009年毕业于四川大学生命科学学院,获得理学博士学位。现工作于中国医学科学院输血研究所,输血传染病中心,研究员,硕士生导师,协和青年教师联盟理事。
教育背景:
2000.9~2004.7 就读于四川大学生命科学学院,专业生物科学,获得理学学士学位
2004.9~2009.7 就读于四川大学生命科学学院,专业动物学,获得理学博士学位
工作:
2009.7至今,在中国医学科学院输血研究所工作,主要从事血液安全领域的研究。
主要研究方向:
1.血液宏基因组学与病原微生物生物信息学研究
2.人类基因组与疾病相关性研究
获奖情况:
1.四川省科学技术进步奖,三等奖(2018-J-3-92-R02),我国血液安全关键技术及保障策略的研究与应用。
承担项目:
1.自然科学基金青年项目:献血/浆人群中人细小病毒B19的亲缘地理学与群体遗传学研究,项目负责人,项目经费23万元;
2.自然科学基金面上项目:HBV、HCV与HIV在重庆地区的遗传多样性、亲缘地理学与群体遗传学研究,项目主要研究者,合作方负责人,项目经费66万元;
3.四川省科技厅应用基础研究:基于深度测序方法检测血液传播新发病原体,项目负责人,项目经费10万元;
4.四川省科技厅国际合作项目:中国多血液中心HIV感染献血者研究,项目主要研究者,项目经费30万元;
5.四川省科技厅重点研发项目:基于宏基因组和培养组深度测序方法建立的导致感染性不明原因发热病原体的鉴定和用药指导研究,项目经费20万元;
6.国际合作项目:The Recipient Epidemiology and Donor Evaluation Study-III,项目中方协调员,项目经费约2000万元。
发表论文情况:
1.Ling Pu, Zuoyi Jian, Fen Pan, Yang Geng, Miao He, Pu Liao. Comparative genomic analysis and multi-drug resistance differences of Acinetobacter baumanniiin Chongqing, China.Infect Drug Resist. 2019 Sep 11; 12: 2827-2838. doi: 10.2147/IDR.S216745. eCollection 2019.
2.Zhan Gao Jing Liu Ping Fu Mei Huang Ru'an Cao Xiuqiong Wen Chunhong Zhang Tao He Wei Mao Dan Liao Ling Ke Yashan Yang Miao He* Yu Liu Jingxing Wang Roger Y. Dodd Paul Ness Hua Shan Estimation of hepatitis B–positive rates in Chinese blood donors by combining predonation and postdonation screening results. TRANSFUSION 2019;00;1–6. doi:10.1111/trf.15158 (Correspondence)
3.P. Zeng, Q. Liao, Z. Gao, M. He* & X. Rong Sero-prevalence and viremia status of dengue virus among asymptomatic blood donors post epidemic outbreak in Chinese Guangzhou in 2015, Transfusion Medicine, 2018. (Correspondence)
4.Ya-Ling Gao, Zhan Gao Miao He* and Pu Liao Infection status of human parvovirus B19, cytomegalovirus and herpes simplex Virus- 1/2 in women with first-trimester spontaneous abortions in Chongqing, China. Virology Journal (2018) 15:74
5.Min Xu, Yashan Yang, Ya Zhou, Zhiyang Liu, Yu Liu, and Miao He* 2017 Metagenomics in pooled plasma, with identification of potential emerging infectious pathogens. TRANSFUSION, 2018 Mar; 58(3):633-637. (Correspondence)
6.Guo Tao, Gao Yaling, Gao Zhan, Liao Pu, He Miao*. Human papillomavirus genotype distribution among HPV-positive women in Sichuan province, Southwest China. Arch Virol. 2018 Jan;163(1):65-72. (Correspondence)
7.Z. Gao, Y. Zhang, Y. Yang, M. Xu,P. Liao, W. He, J. Xu, Y. Liu , M. He* 2017 Dengue virus infections among blood donors in Guangxi of China, 2013–2014. Transfusion Medicine, doi: 10.1111/tme.12448. (Correspondence)
8.Zhan Gao, Yu Zhang, Hua Shan, Ling Shi, Jing Liu, Min Xu, Peibin Zeng, Yu Liu, and Miao He. A 30-year systematic review and meta-analysis of hepatitis B virus among blood donors in mainland China: revealing increase of new threats. TRANSFUSION 2017; 57; 1988–1997. (Correspondence)
9.Zhang Y, Chen LM, He M*. Hepatitis C Virus in mainland China with an emphasis on genotype and subtype distribution. Virology Journal (2017) 14:41. (Correspondence)
10.Zeng P, Liu Y, He M*, Wang J, Keating S, Mao W, et al. (2017) The infection staging and profile of genotypic distribution and drug resistance mutation among the human immunodeficiency virus-1 infected blood donors from five Chinese blood centers, 2012-2014. PLoS ONE 12(6): e**. (Correspondence)
11.He M*, et al, The Impact of Emerging Infectious Diseases on Chinese Blood Safety, Transfus Med Rev, 31 (2017) 94–101.
12.Wang M, Fu P, Yin Y, He M*, Liu Y. PLoS One. Acute, Recent and Past HEV Infection among Voluntary Blood Donors in China: A Systematic Review and Meta-Analysis. Plos One, 2016, 11 (9): e**. (Correspondence)
13.Ya Zhou, Guohui Bian, Qiongxiu Zhou, Zhan Gao, Pu Liao, Yu Liu, and Miao He* 2015 Detection of Cytomegalovirus, Human Parvovirus B19, and Herpes Simplex Virus-1/2 in Women With First-Trimester Spontaneous Abortions. Journal of Medical Virology, 87:1749–1753(Correspondence)
14.Yu Liu, Peibin Zeng, Jingxing Wang, Gui Liu, Min Xu, Ling Ke, Miao He* and Zhong Liu, 2014 Hepatitis B virus infection in a cohort of HIV infected blood donors and AIDS patients in Sichuan, China. J Transl Med. 2014 Jun 12;12:164. (Correspondence)
15.MY Ma, M He, LY Liao, YY Guo, DQ Yu, ZZ Xiong, Y Liu, PB Zeng, P Liao, Molecular epidemiology and population dynamics of Hepatitis B Virus in Dianjiang County, Chongqing, China. Arch. Virol. 2014 Jan; 159 (1): 117-24. (Equalcontribution)
16.Y Liu, HL Ma, SH Chen, JX Wang, G Liu, M Xu, L Ke, and M He*, 2013, Interleukin-28B genetic variations and spontaneous clearance of hepatitis C antibody–positive blood donors in China. Transfusion. 53: 2498-2504. (Correspondence)
17.M He, J Zhu, L Ke, L Gao, ZH Pan, XH Yang, WP Li, HIV/Human parvovirus B19 co-infection in blood donors and clinical patients in Sichuan, China. Blood Transfusion, 2012; 10(4): 502-14.
18.L Ke, M He, CQ Li, Y Liu, L Gao, F Yao, J Li, XH Bi, YL Lv, JX Wang, ML Hirsch, WP Li, 2011, The prevalence of human parvovirus B19 DNA and antibodies in blood donors from four Chinese blood centers. Transfusion, 51: 1909-1918. (Equal contribution)
19.Fu P, Lv Y, Zhang H, Liu C, Wen X, Ma H, He T, Ke L, Wu B, Liu J, He M, Liao D, Wang J, Ness P, Liu Y, Shan H. Hepatitis C virus prevalence and incidence estimates among Chinese blood donors.Transfusion. 2019 Jul 4. doi: 10.1111/trf.15432.
20.E. M. Bloch, Y. Yang, M. He, L. Tonnetti, Y. Liu, J. Wang, Y. Guo, H. Li, D. A. Leiby, H. Shan. A pilot serosurvey of Babesia microti in Chinese blood donors. Vox Sanguinis (2018)
21.Wang M, He M, Wu B, Ke L, Han T, Wang J, Shan H, Ness P, Guo N, Liu Y, Nelson KE. The association of elevated alanine aminotransferase levels with hepatitis E virus infections among blood donors in China. Transfusion. 2017 Feb; 57(2): 273-279.
22.Hongxue Li, Miao He, Peibin Zeng, Zhan Gao, Guohui Bian, Chunhui Yang, and Wuping Li, 2015, The genomic and seroprevalence of human bocavirus in healthy Chinese plasma donors and plasma derivatives. Transfusion, 55:154-163.
23.Bian GuoHui,Yang Chunhui,He Miao,Wang Hong,Liu Jiaxin,Cao Ye,Yang Hong,Liu Zhong,Li Wuping,Three different bacterial detection systems for platelet concentrates under inter-laboratory conditions,Transfusion and Apheresis Science,2013,49,3,600
24.Zeng P, Liu Y, He M, Gao Z, Zhou Y, Bian G, et al. HIV-1 genotypic diversity and prevalence of drug resistance among treatment naive HIV-infected individuals in Chengdu of China. Virus Genes. 2013. DOI 10.1007/s11262-013-0958-3
25.Li C, Xiao X, Yin H, He M, Li J, Dai Y, et al. Prevalence and prevalence trends of transfusion transmissible infections among blood donors at four Chinese regional blood centers between 2000 and 2010. J Transl Med. 2012; 10: 176.
26.Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Julin Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J. Brooks Jackson, and Hua Shan. The human immunodeficiency virus-1 genotype diversity and drug resistance mutations profile of volunteer blood donors from Chinese blood centers. Transfusion. 2012; 52(5): 1041-9.
27.Yu Liu, Jingxing Wang, Yi Huang, Tonghan Yang, Xiaoming Guo, Julin Li, Guoxin Wen, Zhongqiao Yun, Peibin Zeng, Miao He, Min Xu, Gui Liu, Ling Ke, David Wright, Jing Liu, Kenrad Nelson, Hua Shan. Molecular epidemiological study of hepatitis B virus in blood donors from five Chinese blood centers. Arch Virol. 2012; 157(9): 1699-707.
28.M. He, J. C. Feng, S. Y. Liu, P. Guo, E. M. Zhao, 2009 The phylogenetic position ofThermophis(Serpentes: Colubridae), an endemic snake from the Qinghai-Xizang Plateau, China. Journal of Natural History, 43 (7&8): 479-488.
29.M. He, J. C. Feng, E. M. Zhao, The complete mitochondrial genome of the Sichuan hot spring keel-back (Thermophis zhaoermii; Serpentes: Colubridae) and a mitogenomic phylogeny of the snakes. Mitochondrial DNA, 21(1): 8–18.
30.徐敏;黄杨;侯颖;毛伟;马红丽;万建华;何伟兰;黄梅;刘鱼;王憬惺;何苗;2018中国献血人群感染巨细胞病毒CMV 的分子流行病学调查,中国输血杂志,31(5):42-65。
31.张玉; 高瞻; 杨亚闪; 何苗,2017,中国5个地区献血人群HCV基因型分布及进化分析,中国输血杂志,30(5):443-448。
32.胡珀璐;鲍晶晶;印澄;石洁;何苗; 2017,南京地区无偿献血人群HBV感染情况调查,中国输血杂志,30(5):448-451。
33.黄梅;文秀琼;曹汝安;高瞻;付萍;王憬惺;刘静;山华;刘鱼;何苗; 2017,绵阳地区无偿献血者中HBsAg真实流行情况调查:献血前快检以及献血后筛查确证试验结果联合分析,中国输血杂志,30(5):451-453。
34.许纪玲;蔡杰;何苗;杨永林;2017,HEV保护性抗体的制备与功能研究,中国输血杂志,30(5): 459-462。
35.蔡杰;许纪玲;何苗;杨永林;2017,献血者HEV感染后VP13抗体的免疫应答研究,中国输血杂志,30(5):466-469。
36.高瞻;张玉;杨亚闪;徐敏;何苗; 2017,荧光定量检测梅毒筛查阳性献血者中生殖器溃疡病原体的研究,中国输血杂志,30(5):470-472。
37.徐敏;毛伟;何涛;张春红;卫昱燕;高瞻;张玉;何苗; 2017,重庆地区健康献血人群弓形虫抗体检测结果分析,中国输血杂志,30(1):58-60。
38.徐敏,毛伟,何涛,卫昱燕,高瞻,张玉,张春红,廖红梅,刘鱼,曾沛斌,王憬惺,何苗,2016,重庆地区健康献血人群血液宏基因组分析与新发病原体鉴定,中国输血杂志,29(9):895-898。
39.侯颖,高瞻,徐敏,张玉,何苗,2016,我国部分地区献血人群中单纯疱疹病毒感染流行情况,中国输血杂志,2016,29(4):397-399。
40.边国慧,杨春晖,高瞻,徐敏,何苗,2015,梅毒螺旋体-15 脂蛋白的原核表达及其纯化,中国生物制品学杂志,28(8):800-803。
41.边国慧,杨春晖,高瞻,徐敏,何苗,2015,一种新的实时荧光定量PCR 方法对血小板制品细菌污染检测效果的评价,中国输血杂志,28(4):387-390。
42.李佳凌, 巫岳龙, 邹礼乐, 蔡延森, 何苗, 2015, 血液中检测人巨细胞病毒的荧光定量PCR 方法建立及评估, 中国输血杂志,28(6):637-641。
43.何伟兰,李聚林,许建荣,周仲民,庞志向,邓琼,谢文英,刘振北,王憬惺,何苗,2013,柳州地区无偿献血者HBV 遗传分化情况调查,中国输血杂志,26(11):1067-1070。
44.何伟兰,高瞻,许建荣,李聚林,周仲民,庞志向,邓琼,谢文英,刘振北,王憬惺,何苗,2013,柳州地区无偿献血者献血前淘汰原因分析,中国输血杂志,26(11):1071-1072。
45.何苗,高蕾,柯玲,刘鱼,曾沛斌,李武平,2011,中国人细小病毒B19系统发育关系研究,中国输血杂志,24(5):399-402。
46.何苗,柯玲,李武平,2010,中国献血人群中人细小病毒B19的分子流行病学调查,中国输血杂志,23(10):890-891。
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