刘芹防
研究领域：病毒学
电话/传真：
电子邮件：LIUQINFANG@SHVRI.AC.CN
更多信息：
简历（200-500字）：
研究员，中国农业科学院上海兽医研究所, 12. 2014-现在
博士后，兽医学院，美国堪萨斯州立大学, 05. 2010-12.2014
猪病研究组,中国农业科学院哈尔滨兽医研究所, 07. 2009-05. 2010
博士学位,中国农业大学动物医学院, 09. 2004-07. 2009
本科学位,南京农业大学动物科技学院, 09. 2000-06. 2004
获奖及荣誉：
中国农业部“青年杰出农业科学家”，2016
中国农业科学院“青年英才”计划入选者，2014
2013年堪萨斯州立大学兽医学院诊断病理系优秀科研工作者, 2013
堪萨斯州立大学兽医学院Sigma-Phi Zeta 基础科研二等奖，2013
承担科研项目情况：
主持：
1.“十三五” 国家重点研发计划项目：水禽重要疫病免疫防控新技术研究（2017.07-2020.12），水禽专用疫苗佐剂和免疫增强剂的研究与开发，60万元，主持
2. 中国自然科学基金委面上项目，A型流感病毒在出芽过程中对核糖核蛋白体（Ribonucleoprotein，RNP）包装机制研究，(**,2016-2019)，76.8万，主持
3. 中国自然科学基金委面上项目，NA蛋白糖基化修饰对病毒出芽与致病性影响与机制研究 ，(**,2017-2020)，70万，主持
4. 中国自然科学基金委,青年自然科学基金,猪细小病毒非结构蛋白拮抗干扰素功能研究, (**,2010-2013)，19万，主持
5. 中国农业科学院“青年英才”计划， (2014-2019)，250万，主持
6. 中国农业科学院基本科研业务费用， (2015-2016)，30万，主持
7. 中国农业科学院基本科研业务费用院级统筹增量，(2016-2017)，20万，主持
代表论著：
1.B Zhou*, J Ma*, Qinfang Liu*, Bhupinder Bawa, Wei Wang, Reed S. Shabman, Michael Duff, Jinhwa Lee, Yuekun Lang, Juergen A. Richt, David E. Wentworth, Wenjun Ma. Characterization of Uncultivable Bat Influenza Virus Using a Replicative Synthetic Virus. Plos Pathogens. 2014 Oct 2;10(10):e**.
2.Qinfang Liu*, Nacho, Mena, Jingjiao Ma, Bhupinder Bawa, Yuekun Lang, Young Lyoo, Wenjun Ma, Juergen A. Richt. Newcastle disease virus-based H7 and H5 live vaccines completely protect chickens from viral replication and shedding after challenge of H7N9 or H5N1 avian influenza viruses. J Virol. 2015 Jul;89(14):7401-8.
3.Qinfang Liu*, Bin Zhou, Wenjun Ma, Bhupinder Bawa, Jingjiao Ma, Wei Wang, Yuekun Lang, Young Lyoo, Richard Webby, David E. Wentworth, Juergen Richt. Analysis of recombinant H7N9 wild type and mutant viruses in pigs shows Q226L in HA is important for transmission. J Virol. 2014 Jul;88(14):8153-65.
4.Qinfang Liu*, Chuanling Qiao, Henju Marjuki, Bhupinder Bawa, Jingqun Ma, Stephane Guillossou, Richard J. Webby, Jürgen A. Richt, Wenjun Ma. Combination of PB2 271A and SR polymorphism at positions 590/591 is critical for viral replication and virulence of swine influenza virus in cultured cells and in vivo. J Virol. 2012 Jan;86(2):1233-7.
5.Cui H, Shi Y, Ruan T, Li X, Teng Q, Chen H, Yang J, Liu Qinfang*, Li Z*.Phylogenetic analysis and pathogenicity of H3 subtype avian influenza viruses isolated from live poultry markets in China. Sci Rep. 2016 Jun 7;6:27360. doi: 10.1038/srep27360.
6.Ying Shi, Hongrui Cui, Junheng Wang, Qiuyan Chi, Xuesong Li, Qiaoyang Teng, Hongjun Chen, Jianmei Yang, Qinfang Liu*, Zejun Li* Characterizations of H4 avian influenza viruses isolated from ducks in Shanghai Sci Rep. Sci Rep. 2016 Nov 29;6:37843. doi: 10.1038/srep37843.
7.Kong W*, Liu Qinfang*, Sun Y, Wang Y, Gao H, Liu L, Qin Z, He Q, Sun H, Pu J, Wang D, Guo X, Yang H, Chang KC, Shu Y, Liu J.Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs.Sci Rep. 2016 Jun 2;6:27067. doi: 10.1038/srep27067.
8.R. Xue, Y. Tian, T. Hou, D. Bao, H. Chen, Q. Teng, J. Yang,X. Li, G. Wang, Z. Li, Qinfang. Liu*.H9N2 influenza virus isolated from minks has enhanced virulence in mice, Transboundary and Emerging Diseases, 2018 Jun;65(3):904-910
9.Yan L*, Qinfang Liu*, Su X, Teng Q, Bao D, Che G, Chen H, Cui H, Ruan T, Li X, Li Z.Pathogenicity of reassortant H9 influenza viruses with different NA genes in mice and chickens.Vet Res. 2016 Jun 24;47(1):67. doi: 10.1186/s13567-016-0352
10.X. Li*, Y. Shi*, Qinfang Liu*, Y. Wang, G. Li, Q. Teng, Y. Zhang, S. Liu, Z. Li，Airborne Transmission of a Novel Tembusu Virus in Ducks，Journal of Clinical Microbiology. 2015 Aug;53(8):2734-6.
11.Liu Qinfang*, Ma J, Strayer DR, Mitchell WM, Carter WA, Ma W, Richt JA. Emergence of a novel drug resistant H7N9 influenza virus: evidence based clinical potential of a natural IFN-α for infection control and treatment. Expert Rev Anti Infect Ther. 2014 Feb;12(2):165-9.
12.Wencheng Lin, Zheng Qiu, Qinfang Liu*, Shangjin Cui*, Interferon induction and suppression in swine testicle cells by porcine parvovirus and its proteins. Vet Microbiol. 2013 Apr 12;163(1-2):157-61
13.Qiao C*, Liu Qinfang*, Bawa B, Shen H, Qi W, Chen Y, Mok C, García-Sastre A, Richt J, Ma W. Pathogenicity and transmissibility of reassortant H9 influenza viruses with genes from pandemic H1N1 virus. J Gen Virol. 2012 Nov;93(Pt 11):2337-45
14.Qinfang Liu*, Guozhong Zhang, Yu huang, Gaixian Ren, Liben Chen, Jian Gao, Dabing Zhang, Bo Han, Wenliang Su, Jixun Zhao, Xueying Hu, Jingliang Su Isolation and characterization of a reovirus causing spleen necrosis in Pekin ducklings. Veterinary Microbiology. 2011 Mar 24;148(2-4):200-6.
15.Qinfang Liu*, Jingjiao Ma, Zheng Kou, Juan Pu, Fumin Lei, Tianxian Li, Jinhua Liu. Characterization of a H5N1 virus isolated from tree sparrow. Virus Research. 2010 Jan;147(1):25-9
16.Qinfang Liu*, Jingjiao Ma, Haixia Liu, Wenbao Qi, Joe Anderson, Steven C. Henry, Richard A. Hesse, Jürgen A. Richt, Wenjun Ma. Emergence of novel reassortant H3N2 swine influenza viruses with the 2009 pandemic H1N1 genes in the United States. Arch Virol. 2011
17.Lin, W., Wang, Z., Qiu, Z., Liu, Qinfang*, Cui, S*., Establishment of Real-Time TaqMan-Fluorescence quantitative RT-PCR assay for detection and quantitation of ten kinds of porcine inflammation markers mRNA, Journal of Virological Methods, 2013 Oct;193(1):169-72
18.Qinfang Liu*, Bhupinder Bawa, Jingjiao Ma, Feng Li, Wenjun Ma, Jürgen A. Richt, A crucial role of N-terminal domain of influenza A virus M1 protein in interaction with swine importin α1 protein. Virus Genes. 2014 Aug;49(1):157-62
19.Qinfang Liu*, Jixun Zhao, Jingliang Su, Juan Pu, Guozhong Zhang, Jinhua Liu. Full Genome Sequences of Two Reticuloendotheliosis Viruses Contaminating Commercial Vaccine. Avian Diseases. 2009, 53(3):341–346.
20.Danqi B, Li Z, Liu Qinfang*, Richt JA*.H7N9 avian influenza A virus in China: a short report on its circulation, drug resistant mutants and novel antiviral drugs.Expert Rev Anti Infect Ther. 2017 Jul 17:1-5.