陈宗艳

研究领域：禽禽传染病病毒分子生物学分子生物学及与分子免疫学
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电子邮件:zychen@shvri.ac.cn
陈宗艳，女，1981年12月生，，博士，副研究员 硕士研究生导师。2008年获四川农业大学博士学位年毕业于四川农业大学。2008年7月至今，，同年，就职于在中国农业科学院上海兽医研究所工作。；2014-2015年，在美国马里兰大学兽医学院做访问****。主要研究领域为禽病毒分子生物学与免疫学，目前主要致力于禽呼肠孤病毒和副粘病毒的流行病学、致病机理和新型疫苗研究等，参与或主持国家和省部级项目5项。近年来，在国内外学生刊物发表论文20余篇，其中SCI论文15篇；参与编写专著2部；获得国家实用型发明专利2项。

2014年5月－2015年7月在美国马里兰大学的马里兰弗吉利亚区域兽医学院(Virginia-Maryland Regional College of Veterinary Medicine,University of Maryland, The USA) 院长Dr.Samal研究团队进行学术访问，主要从事基于rNDV分析禽副粘病毒流行病学特征、解析致病机理及载体疫苗研发。现已在Emergence Infectious Diseases, Antiviral Research, Virus Research, Veterinary Immunology and Immunopathology, Veterinary Microbiology, Avian pathology, Infection, Genetics and Evolution等刊物发表文章40余篇。参编《现代农业产业技术－养鹅100问》，《动物反向遗传学》。已获授权专利2项，鹅细小病毒抗体间接ELISA检测试剂（专利号：ZL9.8.）及I型鸭肝炎病毒抗体间接ELISA检测试剂盒（专利号：ZL0.3.）。现主持上海市科委科技创新医药与农业领域项目，新型鸭呼肠孤高效细胞灭活疫苗研发（**）；参与农业部公益性行业专项（）、国家自然科学基金（**）和863项目（2011AA10A209）等。
近期发表的论文代表论著：
1.Li C, Chen Z, Meng C, Liu G*. Rapid detection of duck hepatitis A virus genotype C using reverse transcription loop-mediated isothermal amplification. J Virol Methods. 2014,196:193-8.
2.Wang H, Chen Z, Wang X, Li N, Wei J, Sun P, Wang G, Liu G*Isolation and characterization of a Neisseria strain from the liver of a Chinese peking duck. Infection, Genetics and Evolution，2014，25： 1–3
3.Gao J, Chen Z, Li C, Liu G*.Codon optimisation of the rabbit hemorrhagic disease virus (RHDV) capsid gene leads to increased gene expression in Spodoptera frugiperda 9 (Sf9) cells.J Vet Sci. J Vet Sci. 2013，14（4）： 441-447.
4.Cheng Y, Chen Z, Li C, Meng C, Wu R, Liu G*.Protective immune responses in rabbits induced by a suicidal DNA vaccine of the VP60 gene of rabbit hemorrhagic disease virus.Antiviral Res. 2013，97(3):227-31.
5.Wang B, Zhe M, Chen Z, Li C, Meng C, Zhang M, Liu G*. Construction and applications of rabbit hemorrhagic disease virus replicon.PLoS One. 2013 May 8;8(5):e60316.
6.Li C, Chen Z, Meng C, Li L, Liu G*..High yield expression of duck hepatitis A virus VP1 protein in Escherichia coli, and production and characterization of polyclonal antibody. J Virol Methods. 2013 ， 191(1):69-75.
7.Chen Z, Li C, Peng G, Liu G*.Expression, purification, characterization and subcellular localization of the goose parvovirus rep1 protein. Protein Pept Lett. 2013，20(7):820-5.
8.Wang Y, Liu G, Chen Z, Li C, Shi L, Li W, Huang H, Tao C, Cheng C, Xu B, Li G. Recombinant adenovirus expressing F and H fusion proteins of peste des petits ruminants virus induces both humoral and cell-mediated immune responses in goats.Vet Immunol Immunopathol. 2013，154(1-2):1-7.
9.Zongwei Yang，Zongyan Chen ，Chuanfeng Li， Guangqing Liu* .Identification of in vivo interaction between Rabbit Hepatitis Disease Virus capsid protein and minor structural protein. Chinese Sci Bull, 2012, 57:1-5.
10.Zongyan Chen, Yingqi Zhu, Guangqing Liu*.Outbreak associated Novel Duck Reovirus,China, 2011.Emerging Infectious Diseases , 2012, 18(7): 1210-1211.
11.Yuzhi Fu, Zongyan Chen, Chuanfeng Li, Guangqing Liu*, Establishment of a duck cell line susceptible to duck hepatitis virus type. J Virol Methods, 2012, 184: 41-45.
12.Yong Wang, Chuanfeng Li, Zongyan Chen,Binrui Xu, Gang Li, Guangqing Liu*. Complete genome comparison of duck hepatitis virus type 1parental and attenuated strains. Virus Genes, 2012, 45: 398–401
13.Yuzhi Fu, Zongyan Chen, Chuanfeng Li, Guangqing Liu*, Protective immune responses in ducklings induced by a suicidal DNA vaccine of the VP1 gene of duck hepatitis virus type. Vet. Microbiol, 2012, 160(3-4):314-8.
14.Chen Z, Li C, Zhu Y, Wang B, Meng C, Liu G*. Immunogenicity of virus-like particles containing modified goose parvovirus VP2 protein. Virus Res. 2012, 169(1): 306-309.
15.Guangqing Liu*, Emilio Yángüez, Zongyan Chen，Chuanfeng Li. The duck hepatitis virus 5’-UTR possesses HCV-like IRES activity that is independent of eIF4F complex and modulated by downstream coding sequences. Virology Journal, 2011, 8:147-158.
16.Zongyan Chen, Guangqing Liu*. Monoclonal Antibody Specific to Goose Parvovirus VP3 Protein. Hybridoma. 2011, 30(1): 101-102.