姓名：苏昕
职称：副教授
邮箱：xinsu@mail.buct.edu.cn
办公地址：东校区科技大厦西配楼104


教育背景：
2006.09-2010.07 南开大学理学学士化学
2010.09-2015.07 北京大学理学博士分析化学
2013.09-2014.10 美国密西根大学联合培养博士生物物理
工作经历：
2015.07-至今北京化工大学生命科学与技术学院 副教授
主要社会兼职：
中国化学会会员、中国仪器仪表协会会员
奖励与荣誉：
2017年：北京化工大学青年英才
2016年：北京市青年优秀骨干教师
2013年：博士研究生国家奖学金
主要研究方向：
苏昕副教授一直从事先进分析方法和DNA纳米技术研究，在Nature Biotechnology、Chemical Science、Analytical Chemistry、Biosensors & Bioelectronics等期刊发表多篇论文。目前主持国家自然科学基金2项，军工项目1项，北京市优秀人才项目1项，厦门市科技计划项目1项，中央高校科研业务费3项。具体研究方向包括：
1.单分子分析：超高灵敏度肿瘤标志物检测，非扩增核酸检测
2.DNA纳米技术：智能抗肿瘤药物递送，细胞内生物分子高分辨成像
3.核酸生物计算：高速DNA计算，生化反应时钟，人工仿生体系
代表论文：
1. Shuang Cai, Yingnan Deng, Shengnan Fu, Junjie Li, Changyuan Yu, Xin Su^*, Single-Molecule Dynamic DNA Junctions for Engineering Robust Molecular Switches, Chemical Science, 2019, 10, 9922–9927.
2. Yi Zhang, Yingnan Deng, Congshan Wang, Lidan Li, Lida Xu, Yingjie Yu^*, Xin Su^*, Probing and Regulating the Activity of Cellular Enzyme by DNA Tetrahedron Nanostructures, Chemical Science, 2019, 10, 5959-5966.
3. Alexander Johnson-Buck#, Xin Su#, Maria D Giraldez, Meiping Zhao, Muneesh Tewari, Nils G. Walter*, Kinetic fingerprinting to identify and count single nucleic acids, Nature Biotechnology, 2015, 33, 730-732.（共同第一作者）
4. Lidan Li, Na Li, Shengnan Fu, Yingnan Deng, Changyuan Yu^*, Xin Su^*, Base excision repair-inspired DNA motor powered by intracellular apurinic/apyrimidinic endonuclease, Nanoscale, 2019, 11, 1343-1350.
5. Rui Weng, Shengting Lou, Lidan Li, Yi Zhang, Jing Qiu, Xin Su^*, Yongzhong Qian^*, Nils G. Walter^*, Single-Molecule Kinetic Fingerprinting for the Ultrasensitive Detection of Small Molecules with Aptasensors, Analytical Chemistry, 2019, 91, 1424?1431.
6. Yingjie Yu, Liang Ma, Lidan Li, Yingnan Deng, Lidan Xu, Hua Liu, Lehui Xiao^*, Xin Su^*, Digestion of Dynamic Substrate by Exonuclease Reveals High Single-Mismatch Selectivity, Analytical Chemistry, 2018, 90, 13655-13662.
7. Zehao Li^#, Xu Zhou^#, Lidan Li, Shue Liu, Congshan Wang, Lina Li, Changyuan Yu^*, Xin Su^*, Probing DNA Hybridization Equilibrium by Cationic Conjugated Polymer for Highly Selective Detection and Imaging of Single-Nucleotide Mutation, Analytical Chemistry, 2018, 90, 6804-6810.
8. Xin Su, Zehao Li, Xinzhong Yan, Lei Wang, Xu Zhou, Lin Wei, Lehui Xiao^*,Changyuan Yu^*, Telomerase Activity Detection with Amplification-Free Single Molecule Stochastic Binding Assay, Analytical Chemistry, 2017, 89, 3576-3582.
9. Lidan Li, Xianjin Xiao, Jingyang Ge, Manli Han, Xu Zhou, Lei Wang, Xin Su^*, Changyuan Yu^*, Discrimination Cascade Enabled Selective Detection of Single Nucleotide Mutation, ACS Sensors, 2017, 2, 419-425.
10. Yu Feng, Shuang Cai, Guoliang Xiong, Guanfei Zhang, Shihui Wang, Xin Su^*, Changyuan Yu^*, Sensitive Detection of DNA Lesions by Bulge-Enhanced Highly Specific Coamplification at Lower Denaturation Temperature Polymerase Chain Reaction, Analytical Chemistry, 2017, 89, 8084-8091.
11. Junxiu Wang, Guoliang Xiong, Liang Ma, Shihui Wang, Xu Zhou, Lei Wang, Lehui Xiao, Xin Su^*, Changyuan Yu^*, A dynamic sandwich assay on magnetic beads for selective detection of single-nucleotide mutations at room temperature, Biosensors & Bioelectronics, 2017, 94, 305-311.
12. Yingjie Yu, Tongbo Wu, Alexander Johnson-Buck, Lidan Li, Xin Su^*, A two-layer assay for single-nucleotide variants utilizing strand displacement and selective digestion, Biosensors & Bioelectronics, 2016, 82, 248-254.
教师寄语:
对科学存有敬畏之心，以好奇之心去探索
招生要求：
1.学习用功刻苦；2.有责任心，善于沟通；3.富有钻研精神，4.较好的语言文字能力