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shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Geno

本站小编 Free考研考试/2022-01-03

Non-circular plots of whole genomes are natural representations of genomic data aligned along all chromosomes. Currently, there is no specialized graphical user interface (GUI) designed to produce non-circular whole genome diagrams, and the use of existing tools requires considerable coding effort from users. Moreover, such tools also require improvement, including the addition of new functionalities. To address these issues, we developed a new R/Shiny application, named shinyChromosome, as a GUI for the interactive creation of non-circular whole genome diagrams. shinyChromosome can be easily installed on personal computers for own use as well as on local or public servers for community use. Publication-quality images can be readily generated and annotated from user input using diverse widgets. shinyChromosome is deployed at http://150.109.59.144:3838/shinyChromosome/, http://shinyChromosome.ncpgr.cn, and https://yimingyu.shinyapps.io/shinyChromosome for online use. The source code and manual of shinyChromosome are freely available at https://github.com/venyao/shinyChromosome.
全基因组非圆形图是一种沿着所有染色体展示基因组数据的常用方法。到目前为止,仍然没有专门用于创建全基因组非圆形图的图形用户界面程序,而使用现有的非图形界面工具需要用户进行大量的编程工作。此外,现有工具仍需要进一步改进,包括一些新功能的添加等。为了解决这些问题,我们基于R软件的Shiny包开发了一款可用于交互式创建全基因组非圆形图的图形用户界面程序,程序名为shinyChromosome。shinyChromosome可以很容易地安装在个人计算机上供用户自己使用,也可以安装在本地或公共服务器上供其他很多用户使用。通过使用shinyChromosome图形界面程序中提供的很多小控件,用户可以很容易地生成具有发表质量的图形并对图形进行注释。shinyChromosome 被部署在 http://150.109.59.144:3838/shinyChromosome/,http://shinyChromosome.ncpgr.cn和 https://yimingyu.shinyapps.io/shinyChromosome等三个网址供用户在线使用。shinyChromosome的源代码和帮助手册可以在https://github.com/venyao/shinyChromosome免费获得。





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