Name:
Hu Bing （胡兵）
Address:
School of life science,

University of Science and Technology of China, Hefei, Anhui 230027, P. R. China
Tel:
86-
E-mail:
bhu@ustc.edu.cn
Webpage:
http://222.195.69.43/hub/

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　EDUCATION AND RESEARCH EXPERIENCE
1984 – 1989
Bachelor of Biophysics, University of Science and Technology of China
1989 – 1992
Master of Biophysics, University of Science and Technology of China
1993 – 1998
Ph.D. of Neurobiology, University of Hong Kong and Institute of Physiology, Chinese Academy of Sciences, Shanghai, China (joint training)
1996 – 1999
Lecturer, Department of Neurobiology and Biophysics, USTC, China
2000.01 – 2001
Associate Professor, Department of Neurobiology and Biophysics, School of Life Sciences, USTC, China
2002 – 2004
Postdoctoral fellow, University of California at LA, CA,University of California at Irvine, CA
2005 – 2007.08
Senior RA, Research Officer, Department of Anatomy, Faculty of Medicine, University of Hong Kong, Hong Kong, China
2007.11 – present
Professor, Department of Neurobiology and Biophysics, School of Life Sciences, USTC, China


　CURRENT RESEARCH PROJECTS
1.
To study the oligodendrocyte development, myelin formation as well as remyelination after demyelination. Currently, we are focusing on elucidation of the mechanisms underlying zebrafish CNS remyelination after injury.
2.
To study the synapse dynamic change using in vivo time-lapse confocal microscopy imaging in zebrafish and xenopus tadpoles.


　REPRESENTATIVE PUBLICATIONS
1.
Bing Hu, Henry K. Yip and Kwok-Fai So (1998) Localization of p75 neurotrophin receptor in the retina of the adult SD rat: An immunocytochemical study at light and electron microscopic levels. Glia 24:187-197.

2.
Bing Hu, Angeliki Maria Nikolakopoulou and Susana Cohen-Cory (2005) BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo. Development. 132:4285-4298.

3.
Sha Mi*, Bing Hu*, Kyungmin Hahm, Yi Luo, Edward Sai Kam Hui, Qiuju Yuan, Wai Man Wong, Li Wang, Huanxing Su, Tak-Ho Chu, Jiasong Guo, Wenming Zhang, Kwok-Fai So, Blake Pepinsky, Zhaohui Shao, Christilyn Graff, Ellen Garber, Vincent Jung, Ed Xuekui Wu & Wutian Wu* (2007) LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nature Medicine. 13(10):1228-1233. (* these authors contributed equally to this work). Cover page of the issue “the LINGO of remyelination”.

4.
Meng-Hua Xiong,?,? Ya-Juan Li,§,? Yan Bao,§ Xian-Zhu Yang,§ Bing Hu*,§ and Jun Wang*,§ (2012) Bacteria-Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery. Advanced Materials. 24, 6175–6180

5.
Yin, W., Hu, B*. (2014) Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish. Exp. Neurol. 251:72-83. http://dx.doi.org/10.1016/j.expneurol.2013.11.012

6.
Da-long Ren1, Ya-juan Li1, Bing-bing Hu1, Han Wang* 2, 3 and Bing Hu*1 (2015) Melatonin regulates the rhythmic migration of neutrophils in live zebrafish. J Pineal Res., Doi:10.1111/jpi.12230.

7.
Da-Long Ren, Ai-Ai Sun, Ya-Juan Li, Min Chen, Shu-Chao Ge and Bing Hu* (2015) Exogenous melatonin inhibits neutrophil migration through suppression of ERK activation. Journal of Endocrinology. 227 :49–60.

8.
Tian C, Zou S, Hu B* (2016) Extraocular Source of Oligodendrocytes Contribute to Retinal Myelination and Optokinetic Responses in Zebrafish. Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2129-38. doi: 10.1167/iovs.15-17675. (highlight in the same issue)

9.
Chen, M., Xu, Y., Huang, R., Huang Yubin, Ge Shuchao and Hu Bing* (2016) N-Cadherin is Involved in Neuronal Activity-Dependent Regulation of Myelinating Capacity of Zebrafish Individual Oligodendrocytes In Vivo. Molecular Neurobiology, 54(9), 6917-6930. doi:10.1007/s12035-016-0233-4

10.
Xu Y, Chen M, Hu B, Huang R and Hu B* (2017) In vivo Imaging of Mitochondrial Transport in Single-Axon Regeneration of Zebrafish Mauthner Cells. Front. Cell. Neurosci. 11:4. doi: 10.3389/fncel.2017.00004

11.
Huang RC, Chen M, Yang LQ, Wagle M, Guo S and Hu B* (2017) MicroRNA-133b Negatively Regulates Zebrafish Single Mauthner-Cell Axon Regeneration through Targeting tppp3 in Vivo. Front. Mol. Neurosci. 10:375. doi: 10.3389/fnmol.2017.00375

12.
Hu BB, Chen M, Huang RC, Huang YB, Xu Y, Yin W, Li L and Hu B* (2018) In vivo imaging of mauthner axon regeneration, remyelination and synapses re-establishment after laser axotomy in zebrafish larvae. Exp Neurol. 300:67-73. 2018. Feb. https://doi.org/10.1016/j.expneurol.2017.10.028

13.
Chen M, Huang RC, Yang LQ, Ren DL*, Hu B* (2019) In vivo imaging of evoked calcium responses indicates the intrinsic axonal regenerative capacity of zebrafish. FASEB J. 33(6):7721-7733.