Name:
Li Bai, Ph.D.
Address:
Professor, Institute of Immunology


School of Life Sciences


University of Science & Technology of China


443 Huangshan Street, Hefei City, Anhui 230027, P.R.China
Tel:
(551) 6360-7897
E-mail:
baili@ustc.edu.cn

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　EDUCATION AND APPOINTMENT
1997-2001
B.A., Biology, Huazhong University of Science and Technology, Wuhan, China
2001-2006
Ph.D., Biophysics, Huazhong University of Science and Technology, Wuhan, China
2006-2010
Postdoctoral Fellow, Howard Hughes Medical Institute, University of Chicago, Chicago, USA
2010-Present
Professor, Institution of Immunology, University of Science and Technology of China, Hefei, China


　RESEARCH INTERESTS
1.
Metabolic control of NKT cells.
2.
NKT cells in tumor immunity.
3.
Chronic inflammation and type 2 diabetes.


　CURRENT RESEARCH PROJECTS

National Key R&D Program of China, National Natural Science Foundation of China.


　REPRESENTATIVE PUBLICATIONS
1.
Fu S＃, He K, Tian C, Sun H, Zhu C, Bai S, Liu J, Wu Q, Xie D, Yue T, Shen Z, Dai Q, Yu X, Zhu S, Liu G, Zhou R, Duan S, Tian Z, Xu T, Wang H*, Bai L*. Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells. Nature Communications, 2020 Jan 23;11(1):438.
2.
Wang L#, Liu Z#, Wang L, Wu Q, Li X, Xie D, Zhang H, Zhang Y, Gu L, Xue Y, Yue T, Liu G, Ji W, Wei H, Xu T, Bai L*. Spatial distribution of IL4 controls iNKT cell-DC crosstalk in tumors. Cell Mol Immunol. 2019 Jun 3.
3.
Fu S#, Zhu S#, Tian C, Bai S, Zhang J, Zhan C, Xie D, Wang L, Li Z, Li J, Zhang H, Zhou R, Tian Z, Xu T, Bai L*. Immunometabolism regulates TCR recycling and iNKT cell functions. Sci. Signal. 2019 Feb 26;12(570).
4.
Chen Z, Zhu S, Wang L, Xie D, Zhang H, Li X, Zheng X, Du Z, Li J, Bai L*. Memory Follicular Helper Invariant NKT Cells Recognize Lipid Antigens on Memory B Cells and Elicit Antibody Recall Responses. J Immunol. 2018 May 1;200(9):3117-3127.
5.
Zhang HM#, Xue RF#, Zhu SS, Fu SC, Chen ZL, Zhou RB, Tian ZG, Bai L*. M2-specific reduction of CD1d switches NKT cell-mediated immune responses and triggers metaflammation in adipose tissue. Cellular & Molecular Immunology. 2018 May;15(5):506-517.