毕国强

Tel:86-
E-mail:gqbi@ustc.edu.cn
ChinaAddress:School of Life SciencesUniversity of Science and Technology of China230026 Hefei, P. R.China


主要研究兴趣：
Synaptic structure and plasticity
Neural circuitstructure and dynamics
Learning, memory and related brain diseases
Ultra-high resolution optical and electron imaging


教育和研究经历：
1985-1989,B.S. (Physics), Beijing University, China　
1990-1991,M.S.Physics), New York University, USA　
1991-1996,Ph.D. (Biophysics), University of California, Berkeley, USA　
1996-2000,Postdoctoral Fellow, University of California, San Diego, USA　
2000-2009,Assistant Professor, Associate Professor (with tenure), University of Pittsburgh School of Medicine, USA　
2007- ,Professor, University of Science and Technology of China　
2014- ,Senior Investigator, CAS Center for Excellence in Brain Research

科研项目：
National Outstanding Young Scientist Award, National Natural Science Foundation of China (2007-2011)
Dynamic Assembly of Protein Complex, Ministry of Science and Technology of China (2007-2012)

主要论著：
[01] Shim SH, Xia C, Zhong G, Babcock HP, Vaughan JC, Huang B, Wang X, Xu C, Bi GQ* & Zhuang X*, Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. Proc Natl Acad Sci U S A 109: 13978-13983 (2012).
[02] Zhang JC, Lau PM & Bi GQ*, Gain in sensitivity and loss in temporal contrast of STDP by dopaminergic modulation at hippocampal synapses. Proc Natl Acad Sci U S A 106: 13028-13033 (2009).
[03] Lau, PM & Bi, GQ*, Synaptic mechanisms of persistent reverberatory activity in neuronal networks. Proc Natl Acad Sci U S A 102: 10333-10338 (2005).
[04] Bi, GQ*& Rubin, J Timing in synaptic plasticity: from detection to integration. Trends Neurosci 28: 222-228 (2005).
[05] Wang HX, Gerkin, RC, Nauen, DW& Bi, GQ*,Coactivation and timing-dependent integration of synaptic potentiation and depression. Nat Neurosci 8: 187-193 (2005).
[06] Bi, GQ*& Poo, MM*, Synaptic modifications by correlated activity: Hebb's postulate revisited. Ann Rev Neurosci 24: 139-166 (2001).
[07] Bi, GQ*& Poo, MM, Distributed synaptic modification in neural networks induced by patterned stimulation. Nature 401: 792-796 (1999).
[08] Bi, GQ & Poo, MM,Synaptic modifications in cultured hippocampal neurons: Dependence on spike timing, synaptic strength, and postsynaptic cell type. J Neurosci 18: 10464-10472 (1998).
[09] Steinhardt, RA,Bi, GQ &AldertonJM, Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release. Science 263: 390-393 (1994)