刘行
单位：生命科学学院
地址：合肥市黄山路443号
邮编：230027
电话：86-
个人主页：
实验室介绍：


个人简历 Personal resume


国家自然科学基金委“优秀青年科学基金”获得者（2019），中国科学技术大学特任教授。2014年毕业于中国科学技术大学并获细胞生物学博士学位。主要从事类器官化学生物学与细胞器动力学研究，重点剖析三维类器官模式体系细胞命运抉择过程中细胞器动力学机制与化学生物学调控。已在Nat Chem Biol、Cell Res、PNAS 等国际学术期刊发表近40篇论文。


研究方向 Research direction


1、 细胞有丝分裂的化学生物学研究
2、 细胞器互作与类器官可塑性调控研究
3、 无膜细胞器与细胞命运抉择机制研究



招生信息 Enrollment information


招生专业：细胞生物学，化学生物学，生物物理学，分析化学


论文专著 The monograph Researcher ID


1)BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules - Cell Research - 201907 - 29(7):562-578
2)Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation - Nat Chem Biol - 201604 - 12(4):226-32
3)Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment - Proc Natl Acad Sci U S A - 201508 - 112(33):E4546-55
4)Acetylation of ACAP4 regulates CCL18-elicited breast cancer cell migration and invasion - J Mol Cell Biol - 201812 - 10(6):559-572
5)LRIF1 interacts with HP1α to coordinate accurate chromosome segregation during mitosis - J Mol Cell Biol - 201812 - 10(6):527-538
6)MST4 phosphorylates ACAP4 to orchestrate apical membrane remodeling during gastric acid secretion - J Biol Chem - 201709 - 292(39):16174-16187
7)Phosphorylation of PP1 regulator Sds22 by PLK1 ensures accurate chromosome segregation - J Biol Chem - 201609 - 291(40):21123-21136
8)Adaptor protein APPL1 interacts with EGFR to orchestrate EGF-stimulated signaling - Sci Bull - 201608 - 61(19): 1504-1512
9)IRE1-RACK1 axis orchestrates ER stress preconditioning-elicited cytoprotection from ischemia/reperfusion injury in liver - J Mol Cell Biol - 201604 - 8(2):144-56
10)Chromatin protein HP1 interacts with the mitotic regulator borealin protein and specifies the centromere localization of the chromosomal passenger complex - J Biol Chem - 201407 - 289(30):20638-49