王毅
性别:
男
专业名称:
农药学
研究方向:
新农药创制、荧光技术在农药领域的应用和环境污染物的潜在毒性研究
行政职务:
农药学教研室主任
E-mail:
wangyiahau.edu.cn
通讯地址:
安徽省合肥市长江西路130号
邮政编码:
230036
博士,教授,博士生导师,农药学教研室主任。
主要研究方向:新农药创制、农药残留、荧光传感器、农产品质量安全。近年来,主持了国家自然科学基金青年项目1项、面上项目1项,农业农村部农药残留限量标准制定项目4项,安徽农业大学高层次人才项目,企业委托项目4项,参与国家基金、省部级项目多项,并指导国家级、省级大学生创新训练项目4项。发表30余篇SCI,以第一作者或通讯作者在Journal of Hazardous Materials、Analytical Chemistry、Analytica Chimica Acta、Journal of Agricultural and Food Chemistry、Environmental Pollution、Science of the Total Environment等中科院一区期刊上发表20余篇SCI,担任Sensors and Actuators B: Chemical、Journal of Hazardous Materials、Journal of Agricultural and Food Chemistry等期刊审稿人,以第一发明人授权国家发明专利3项,在申请专利1项。合作培养1名博士生,指导10名硕士生。
为安徽农业大学农药科学系学术骨干,农产品质量安全团队核心成员。依托安徽省农产品安全重点实验室,农业农村部安徽农业大学农药残留检测中心和农业部农产品贮藏保鲜质量安全风险评估实验室(合肥),具备先进的平台和豪华的仪器设备。
热忱欢迎有植保、环境、化学化工和其它相关专业背景的同学加入!
学习和工作经历:
1.2005/09-2009/07,中国农业大学,化学,学士
2.2009/09-2014/07,中国农业大学,农药学,博士,导师:刘尚钟 教授
3.2014/07-2018/12,安徽农业大学,资源与环境学院,讲师
4.2018/12-至今,安徽农业大学,资源与环境学院,副教授
5.2017/3-至今,安徽农业大学,资源与环境学院,农药学教研室主任
6.2019-2020,美国加州大学戴维斯分校,访问****,Bruce Hammock院士实验室
7.2020/12-至今,入选安徽农业大学“神农****”英才计划,教授,博士生导师
主讲课程:
为本科生讲授《农药学》、《农药残留分析》、《农产品安全与检测》和《农业污染与防治》的理论与实验课程;为研究生开设《农药分子设计与合成》、《有害生物测定》课程
科研情况:
1. 国家自然科学基金面上项目,新型介孔二氧化硅纳米颗粒的构建及负载丙硫菌唑在大豆植株中的吸收、分布和代谢规律研究(**),58万元,2021.01-2024.12,主持
2. 国家自然科学基金青年科学基金项目,新型增强型比率半胱氨酸荧光探针的合成及特异性识别机理(**),20万元,2017.01-2019.12,主持,
3. 农业农村部标准制定专项,阿维菌素在绿豆、香蕉、苦瓜、黄秋葵中的残留限量标准制定及残留试验(****),68万元,2018.03-2018.12,主持
4. 定远县农业委员会,定远县典型流域农业面源污染综合治理,159万元,2018.11-2020.12,主持
5. 安徽农业大学高层次人才项目,100万元,2021.1-2025.12,主持
论文论著:
1. Meiqing Zhu, Zongyuan Zhao, Xina Liu, Panpan Chen, Fugang Fan, Xiangwei Wu, Rimao Hua*, Yi Wang*. A novel near-infrared fluorimetric method for point-of-care monitoring of Fe2+ and its application in bioimaging. Journal of Hazardous Materials. 2021, 406, 124767. (Top 期刊,中科院一区,JCR 一区,IF:9.038)
2. Meiqing Zhu, Fugang Fan, Yan Huang, Fugang Fan, Fu Wang, Weilun Li, Xiangwei Wu, Rimao Hua*, Yi Wang*. Hydrazine exposure: A near-infrared ICT-based fluorescent probe and its application in bioimaging and sewage analysis. Science of The Total Environment. 2021, 759, 143102.(Top 期刊,中科院一区,JCR 一区,IF:6.551)
3. Meiqing Zhu, Yimin Xu, Linfeng Sang, Zongyuan Zhao, Lijun Wang, Xiaoqin Wu, Fugang Fan, Yi Wang*, Hui Li. An ICT-based fluorescent probe with a large Stokes shift for measuring hydrazine in biological and water samples. Environmental Pollution 2020,113427. (Top 期刊,中科院一区,JCR一区,IF:6.792)
4. Zhenfeng Li#, Yi Wang#, Natalia Vasylieva, Debin Wan, Zihan Yin, Jiexian Dong, and Bruce D. Hammock*. An ultrasensitive bioluminescent enzyme immunoassay based on nanobody/nanoluciferase heptamer fusion for the detection of tetrabromobisphenol A in sediment. Analytical Chemistry 2020, 92, 10083-10090. (Top 期刊,中科院一区,JCR一区,IF:6.785)
5. Lijun Wang, Xiaoqin Wu, Zongyuan Zhao, Fugang Fan, Meiqing Zhu, Yi Wang*, Risong Na*, Qing X. Li. Interactions between imidacloprid and thiamethoxam and dissolved organic matter characterized by two-dimensional correlation spectroscopy analysis, molecular modeling, and density functional theory calculations. Journal of Agricultural and Food Chemistry 2020, 68, 2329-2339. (Top 期刊,中科院一区,JCR 一区,IF:4.192)
6. Meiqing Zhu, Wenliang Wang, Jia Liu, Risong Na*, Zhenfeng Li*, Yi Wang*. A novel pyrene-based fluorescent probe for the rapid and efficient detection of Co2+ in HeLa cells and natural water samples. Journal of Molecular Liquids 2020, 303, 112680. (中科院二区,JCR一区,IF:5.065)
7. Lijun Wang#, Xiaoqin Wu#, Yanan Yang, Xina Liu, Meiqing Zhu, Shisuo Fan, Zhen Wang, Jiaying Xue, Rimao Hua, Yi Wang*, Qing X Li. Multi-spectroscopic measurements, molecular modeling and density functional theory calculations for interactions of 2,7-dibromocarbazole and 3,6-dibromocarbazole with serum albumin. Science of the Total Environment 2019, 686, 1039-1048. (Top 期刊,中科院一区,JCR一区,IF:6.551)
8. Meiqing Zhu, Lijun Wang, Xiaoqin Wu, Risong Na*, Yi Wang*, QingX Li, Bruce D Hammock. A novel and simple imidazo[1,2-a]pyridin fluorescent probe for the sensitive and selective imaging of cysteine in living cells and zebrafish. Analytica Chimica Acta 2019, 1058, 155-165.(中科院二区,JCR一区,IF:5.977)
9. Meiqing Zhu, Fugang Fan, Zongyuan Zhao, Xiaoqin Wu, Lijun Wang, Risong Na*, Yi Wang*. An ICT-based ratiometric fluorescent probe for cysteine and its application in biological issues. Journal of Molecular Liquids 2019, 296, 111832. (中科院二区,JCR一区,IF:5.065)
10. Meiqing Zhu, Xina Liu, Yanan Yang, Lijun Wang, Xiaoqin Wu, Shisuo Fan, Zhen Wang, Rimao Hua*, Yi Wang*, QingX Li. A ratiometric fluorescence probe with large stokes based on excited-stated intramolecular proton transfer (ESIPT) for rapid detection and imaging of biothiols in human liver cancer HepG2 cells and zebrafish. Journal of Molecular Liquids 2019, 287, 111016. (中科院二区,JCR一区,IF:5.065)
11. Meiqing Zhu#, Xiaoqin Wu#, Linfeng Sang, Fugang Fan, Lijun Wang, Xiangwei Wu, Rimao Hua, Yi Wang*, Qing X. Li. A novel and effective benzo[d]thiazole-based fluorescent probe with dual recognition factors for highly sensitive and selective imaging of cysteine in vitro and in vivo. New Journal of Chemistry 2019, 43,13463-13470. (中科院三区,JCR 二区,IF:3.288)
12. Yi Wang*, Lijun Wang, Meiqing Zhu, Jiaying Xue, Rimao Hua*, QingX Li. Comparative studies on biophysical interactions between gambogic acid and serum albumin via multispectroscopic approaches and molecular docking. Journal of Luminescence 2019, 205, 210-218. (中科院二区,JCR一区,IF:3.280)
13. Yi Wang#, Jia Liu#, Meiqing Zhu, Lijun Wang, Xianyang Zen, Shisuo Fan, Zhen Wang, Honglian Li, Risong Na, Xi Zhao, QingX Li. Biophysical characterization of interactions between falcarinol-type polyacetylenes and human serum albumin via multispectroscopy and molecular docking techniques. Journal of Luminescence 2018, 200, 111-119. (中科院二区,JCR一区,IF:3.280)
14. Yi Wang*, Lijun Wang, Erkang Jiang, Meiqing Zhu, Zhen Wang, Shisuo Fan, Qian Gao, Shangzhong Liu, Qing X. Li, and Rimao Hua* A colorimetric and ratiometric dual-site fluorescent probe with 2,4-dinitrobenzenesulfonyl and aldehyde groups for imaging of aminothiols in living cells and zebrafish. Dyes and Pigments 2018,156,338-347(Top 期刊,中科院一区,JCR一区,IF:4.613)
15. Meiqing Zhu, Lijun Wang, Hao Zhang, Shisuo Fan, Zhen Wang, Qing X. Li; Yi Wang*, Shangzhong Liu*, Interactions between tetrahydroisoindoline-1,3-dione derivatives and human serum albumin via multiple spectroscopy techniques. Environmental Science and Pollution Research 2018, 25(18), 17735–17748(中科院三区,JCR二区, IF:3.056)
16. Meiqing Zhu, Lijun Wang, Yu Wang, Jie Zhou, Jie Ding, Wei Li, Yue Xin, Shisuo Fan, Zhen Wang, Yi Wang*, Biointeractions of herbicide atrazine with human serum albumin: UV-vis, fluorescence and circular dichroism approaches. International Journal of Environmental Research and Public Health 2018,15(1),116-131.(中科院三区, JCR二区,IF:2.849)
17. Yi Wang, Meiqing Zhu, Erkang Jiang, Rimao Hua*, Risong Na*, QingX. Li. A simple and rapid turn on ESIPT fluorescent probe for colorimetric and ratiometric detection of biothiols in living cells. Scientific Reports 2017, 7 (中科院三区,JCR一区,IF:3.998)
18. Yi Wang, Meiqing Zhu, Jia Liu, Risong Na, Feng Liu, Xiangwei Wu, Shisuo Fan, Zhen Wang, Dandan Pan, Jun Tang, QingX. Li, Rimao Hua*, Shangzhong Liu*. Comparative interactions of dihydroquinazolin derivatives with human serum albumin observed via multiple spectroscopy. Applied Sciences 2017, 7(2): 200-216(中科院三区,JCR二区,IF:3.044)
19. Yi Wang, Meiqing Zhu, Feng Liu, Xiangwei Wu, Dandan Pan, Jia Liu, Shisuo Fan, Zhen Wang, Jun Tang, Risong Na, QingX. Li, Rimao Hua*, Shangzhong Liu*. Comparative studies of interactions between fluorodihydroquinazolin derivatives and human serum albumin with fluorescence spectroscopy. Molecules 2016, 21(10): 1373-1386(中科院三区,JCR 二区,IF: 3.267)
20. Risong Na, Meiqing Zhu, Shisuo Fan, Zhen Wang, Xiangwei Wu, Jun Tang, Jia Liu, Yi Wang*, Rimao Hua*. A simple and effective ratiometric fluorescent probe for the selective detection of cysteine and homocysteine in aqueous media. Molecules 2016, 21(8): 1023-1031 (中科院三区,JCR 二区,IF: 3.267)
21. Yi Wang, Lei Guo, Suzhen Qi, Hao Zhang, Kechang Liu, Ruiquan Liu, Pei Liang, John E. Casida, Shangzhong Liu*. Fluorescent probes for insect ryanodine receptors: candidate anthranilic diamides, Molecules 2014, 19: 4105-4114. (中科院三区,JCR 二区,IF:3.267)
专利著作教材:
授权专利:
(1) 王毅,花日茂,吴祥为等. 一种具有杀线虫活性的四唑磷酸酯化合物及合成方法(2017年12月15日,授权专利号:6.9)
(2) 王毅,朱美庆,蒋而康等.一种用于生物硫醇检测的ESIPT型荧光探针及应用(2020年6月26日,授权专利号:3.7)
(3) 王毅,朱美庆,王莉君等. 一种用于半胱氨酸特异性检测的荧光化合物及制备方法(2020年12月11日,授权专利号:7.0)
著作教材:
1. “十三五”规划教材《农药学实验指导》(省部级,副主编),中国农业大学出版社,2016年,ISBN:06
2. 《有机磷化学中的不对称合成方法、催化及应用》(译著),化学工业出版社,2020年,ISBN:91
获奖情况:
2016年获得国家农产品质量安全风险评估工作优秀个人