姓 名：胡青莲

性 别：女

工作部门：生物工程学院技术职称：副教授
最高学位：博士民 族：汉族
籍 贯：湖北随州联系方式：
Email: huqinglian@zjut.edu.cn

电 话：0571-88320742
主要研究方向：

1. 纳米药物载体在肿瘤诊断与治疗中的应用；
2. 纳米材料的安全性评估；
目前研究项目：

1．功能型聚集诱导发光纳米粒的制备及在肿瘤光学免疫治疗中的应用

（51603186，国家青年基金，21 万）
发表的论文、专著、教材：
1 Qinglian Hu, Meng Gao, Guangxue Feng, Bin Liu*, Mitochondria-Targeted Cancer Therapy Using a
Light-up Probe With Aggregation-induced Emission Characteristics, Angew. Chem.-Int. Edit., 2014,
53(51), 14225-14229，IF=11.994 （高被引论文）；
2 Qinglian Hu, Min Wu, Chun Fang, Changyong Cheng, Mengmeng Zhao, Weihuan Fang, Paul
K. Chu, Yuan Ping*, Guping Tang*, Engineering nanoparticle-coated bacteria as oral DNA
vaccines for cancer immunotherapy, Nano Letters, 2015, 8; 15(4):2732-2739, IF=12.712；
3 Qinglian Hu, Meng Gao, Guangxue Feng, Xiaodong Chen, Bin Liu*, A Cell Apoptosis Probe

Based on Fluorogen with Aggregation-induced emission Characteristics, ACS Appl. Mat. & Inter.,
2015, 7(8), 4875–4882, IF=7.504;
4 Hu Q, Guo F, Zhao F, Fu Z*，Effects of titanium dioxide nanoparticles exposure on
parkinsonism in zebrafish larvae and PC1, Chemosphere, 2017, 16(173) : 373-379, IF=4.208;
5 Hu Q, Guo F, Zhao F, Tang G, Fu Z*，Cardiovascular toxicity assessment of poly (ethylene imine)-
based cationic polymers on zebrafish model，Journal of Biomaterials Science Polymer Edition,
2017，2017; 28(8):768-780;
6 Hu Q, Zhao F, Guo F, Wang C, Fu Z*, Polymeric Nanoparticles Induce NLRP3 Inflammasome Activation
and Promote Breast Cancer Metastasis, 2017 ， doi: 10.1002/mabi.201700273, IF=3.238;
7 Zhang CJ #, Hu QL#, Feng GX , Zhang RY, Yuan YY, Lu XM ,Liu B*, Image-guided
combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular
probe with aggregation-induced emission characteristics. Chem. Sci., 2015, 6 (8):
4580-4586, IF=8.68, (共同一作)；
8 Meng Gao#, Qinglian Hu#, Guangxue Feng, Nikodem Tomczak , Rongrong Liu, Bengang Xing,
Ben Zhong Tang, Bin Liu*, A multifunctional probe with aggregation-Induced
emission characteristics for selective fluorescence imaging and photodynamic killing of
bacteria over mammalian cells, Adv. Healthc. Mat., 2015, 4(5):659-663，IF=5.110，（co-first author）；
9 Gao Meng#, Hu Qinglian#, Guangxue Feng，Benzhong Tang, Liu Bin*， Fluorescentlight-up
probe with “AIE + ESIPT” characteristics for specific detection of lysosomal esterase. Journal of
Materials Chemistry B. 2014, 2, 3438-3442，IF=4.543（co-first author）；
研究生培养等教学情况

1 浙江省新苗计划资助 1 项（指导教师，2017）
2 生物工程学院“运河杯”课外科技活动竞赛一等奖（指导教师，2017）