于海宁

工作部门:药学院\药物化学
性别:女
技术职称:高校副教授
最高学位:博士
民族:汉族
籍贯:山东省

于海宁：女（1977－），博士，副教授。2004年毕业于浙江大学，获得博士学位，主要从事天然产物的分离纯化和生物学活性研究；2004.06-2006.03在浙江大学生物学专业从事博士后研究。2006年3月进入浙江工业大学药学院从事天然药物的教学及科研工作。2010.03-2011.03赴美国芝加哥大学合作研究。先后主持和参加中国博士后基金，山东省优秀青年科学家奖励基金，浙江省重大专项，浙江省科技厅面上项目，湖州市科技攻关项目等；发表论文30余篇，其中SCI论文、EI论文近20篇；获得国家发明专利4项。主要研究方向：1.植物中活性物质的分离及筛选；2.功能成分的利用及新产品创制；3.植物内生菌与植物药用品质形成的关系研究；4.植物内生菌在生物转化中的应用及其代谢产物中活性物质筛选5.活体影像技术在药物开发中的新方法构建。主要研究论文：1.YuHaining,ZhangLancui,YangJunguo,DasUN,ShenShengrong.Effectoflaminintyrosine-isoleucine-glycine-serine-argininepeptideonthegrowthofhumanprostatecancer(PC-3)cellsinvitro.EurJPharmacol.2009,616(1-3):251-255.2.YangJunguo,YuHaining,SunShili,ZhangLancui,HeGuoqing,DasUN,RuanHui,ShenShengrong.Epigallocatechin-3-gallateaffectsthegrowthofLNCaPcellsviamembranefluidityanddistributionofcellularzinc.JZhejiangUnivSciB.2009,10(6):411-421.3.ZhangLancui,YuHaining,SunShili,YangJunguo,HeGuoing,RuanHui,ShenShengrong.Investigationsofthecytotoxicityofepigallocatechin-3-gallateagainstPC-3cellsinthepresenceofCd2+invitro.ToxicolInVitro.2008,22(4):953-960.4.SunShili,HeGuoqing,YuHaining,YangJunguo,BorthakurD,ZhangLancui,ShenShengrong,DasUN.FreeZn2+enhancesinhibitoryeffectsofEGCGonthegrowthofPC-3cells.MolNutrFoodRes.2008,52(4):465-471.5.YuHaining,YinJunjie,ShenShengrong.GrowthinhibitionofprostatecancercellsbyepigallocatechingallateinthepresenceofCu2+.JournalofAgricultureandFoodChemistry.2004Feb11:52(3):462-466.6.SHENSheng-rong,YUHai-ning,JINChao-fang.InfluenceofgreenteapolyphenolsonmitochondrialpermeabilitytransitionporeandCa2+transport.JournalofZhejiangUniversitySCIENCE.2002Vol.3No.4p.475-479.7.HainingY,ShengrongS,YaokangX.Cytotoxicityofepigallocatechin-3-gallatetoLNCaPcellsinthepresenceofCu2+.JournalofZhejiangUniversitySCIENCE.2005,2:125-131.8.HainingY,JunjieY,ShengrongS.Effectsofepi-gallocatechingallateonPC-3cellscytoplasmicmembraneinthepresenceofCu2+.FoodChemistry.2006,95(1):108-115.9.HainingYu,JunjieYin,ShengrongShen.EffectsofinteractionsofEGCGandCd(2+)onthegrowthofPC-3cellsandtheirmechanisms.FoodChemToxicol.2007,45(2):244-249.10.ShengrongShen,HainingYu,PingChen,JunjieYin,YaokangXiong.Fattyacidsinteashoots(Camelliasinensis(L.)O.Kuntze)andtheireffectsonthegrowthofretinalRF/6Aendothelialcelllines.MolNutrFoodRes.2007,51(2):221-228.11.YuHN,MaXL,YangJG,ShiCC,ShenSR,HeGQ.Comparisonofeffectsofepigallocatechin-3-gallateonhypoxiainjurytohumanumbilicalvein,RF/6A,andECV304cellsinducedbyNa(2)S(2)O(4).Endothelium.2007,14(4-5):227-231.12.HainingYu,ShengrongShen,JunjieYin.Effectsofmetalions,catechins,andtheirinteractionsonprostatecancer.CritRevFoodSciNutr.2007,47(8):711-719.13.ShiliSun,GuoqingHe,HainingYu,JunguoYang,DevajitBorthakur,LancuiZhang,ShengrongShen,UndurtiNDas.FreeZn2+enhancesinhibitoryeffectsofEGCGonthegrowthofPC-3cells.MolecularNutritionandFoodResearch.2008,52(4):465-471.14.ChenXun,YuHaining,ShenShengrong,YinJunjie.RoleofZn2+inepigallocatechingallateaffectingthegrowthofPC-3cells.JTraceElemMedBiol.21(2):125-131.2007Mar27.