钟卫鸿
工作部门:生物与环境工程学院生物工程学科
性别:男
技术职称:高校教授
最高学位:博士
民族:汉族
籍贯:浙江兰溪市
　　1、教育背景
1993年7月,南京大学生物系硕士研究生毕业,获理学硕士学位；
2001年3月,浙江大学生物化工专业博士研究生毕业,获工学博士学位；
2003年2月至2004年2月,美国UniversityofSouthFlorida,博士后访问研究;
2009年7月至9月,美国RensselaerPolytechnicInstitute,CenterforBiotechnologyandInterdisciplinaryStudy,访问教授
　2、工作简历
1993年至今，浙江工业大学生物与环境工程学院，从事应用和环境微生物及基因工程技术方向研究。承担微生物学，代谢工程，基因工程技术等课程教学，2005年省精品课程“基因工程技术”负责人。2007年国家精品课程“微生物学”骨干教师。2004年入选校“高层次创新性人才培养计划”首批青年学术带头人支持计划。2006年、2010年分别入选浙江省新世纪151人才工程第二层次、第一层次。2001年、2003年、2006年分别聘为生物化工、微生物学和生物化学与分子生物学专业硕士研究生导师，2008年聘为生物化工专业博士研究生导师。2006年任生物化学与分子生物学硕士学位点和研究团队负责人。
　　3、学术团体兼职
美国化学学会会员，浙江省微生物学会理事，中国环境科学学会固体废物专业委员会委员。
　　4、近期主持的主要科研项目：
[1]国家自然科学基金项目,大肠杆菌K5产肝素前体heparosan代谢控制研究,2011-2013
[2]教育部博士点基金(博导类)，大肠杆菌K5产聚糖胺药物前体heparosan过程机理与强化，2012-2014
[3]浙江省科技厅国际合作项目,大肠杆菌K5产聚糖胺药物前体及其衍生药物研究,2011-2013
[4]浙江省科技厅重点项目,废烟叶高值利用与减害关键生物技术研究与应用,2007-2009
[5]国家863项目(子项),空气净化器与示范应用(净化用菌种和关键酶研究与应用),2007-2010
[6]浙江中烟工业公司项目,烟叶烟碱降解菌的筛选和降解特性,2008-2011
[7]浙江省自然基金项目,荧光蛋白基因在硝化细菌中的高效表达及生物膜构效关系,2005-2007
5、近期发表主要论著：
InEnglish
Year2012
[21]LiZhong,WanxinWu,WeihongZhong*,JingJin,WenwenChen,LequanQiu,ShijinWu,JianmengChen,Formaldehyde-metabolizingcharacteristicsandkeyenzymegeneanalysisofthenewlyisolatedPseudomonasputidaxyz-zjut,JournalofHazardousMaterials,2012,submitted
[20]LeiZhao,ChenjingZhu,YangGao,ChangWang,XuanzhenLi,MingShu,YupingShi,WeihongZhong*,NicotinedegradationenhancementbyPseudomonasstutzeriZCJduringagingprocessoftobaccoleaves,WorldJournalofMicrobiologyandBiotechnology(SCI,IF1.2),2012,inpress,DOI:10.1007/s11274-012-1010-9
[19]MinWei,ZhuoyiKong,LeiZhao,YanshengLi,LiZhong,XuanzhenLi,WeihongZhong*,Constructionofanativepromoter-containingtransposonvectorforstablemonitoringthedenitrifyingbacteriumPseudomonasstutzeriLYS-86bychromosomalintegratedgfp,Plasmid(SCI,IF1.78),2012,inpress,DOI:10.1016/j.plasmid.2012.02.002
[18]LequanQiu,HanbingDing,WeijianWang,ZhuoyiKong,XuanzhenLi,YupingShi,WeihongZhong*,CoenzymeQ10productionbyimmobilizedSphingomonassp.ZUTE03withconversion-extractioncoupledprocessinathree-phasefluidizedbedreactor,EnzymeandMicrobialTechnology(SCI,IF2.287),2012,50:137-142(doi:10.1016/j.enzmictec.2011.11.006)
Year2011
[17]LequanQiu,WeijianWang,WeihongZhong*,LiZhong,JianjunFang,XuanzhenLi,ShijinWu,JianmengChen,CoenzymeQ10productionbySphingomonassp.ZUTE03withnovelprecursorsisolatedfromtobaccowasteinatwo-phaseconversionsystem,JournalofMicrobiologyandBiotecholgy(SCI,IF2.06),2011,21(5):494-502(doi:10.4014/jmb.1012.12017)
[16]ShijinWu,ErmiaoWu,LequanQiu,WeihongZhong,JianmengChen*,Effectsofphenanthreneonthemortality,growth,andanti-oxidantsystemofearthworms(Eiseniafetida)underlaboratoryconditions.Chemosphere(SCI,IF3.295),2011,83:429-434
[15]WeihongZhong,YixiaoLi,KedanSun,JingJin,XuanzhenLi,FumingZhang,andJianmengChen,Aerobicdegradationofmethyltert-butyletherinaclosedsymbioticsystemcontainingamixedcultureofChlorellaellipsoideaandMethylibiumpetroleiphilumPM1,JournalofHazardousMaterials(SCI,IF4.14),2011,185:1245-1255(DOI:10.1016/j.jhazmat.2010.10.038)
[14]LyM.WangZY,LaremoreTN,ZhangFM,ZhongWH,PuD,ZagorevskiDV,DordickJ,LinhardtRJ.AnalysisofE.coliK5capsularpolysaccharideheparosan,AnalyticalBioanalyticalChemistry(SCI,IF3.328),2011,399:737–745(doi:10.1007/s00216-010-3679-7)
[13]WHZhong*,WJWang,ZYKong,BWu,LZhong,XZLi，JYu,FMZhang,CoenzymeQ10productiondirectlyfromprecursorsbyfreeandgelentrappedSphingomonassp.ZUTE03inawater-organicsolvent,two-phaseconversionsystem,AppliedMicrobiologyandBiotechnology(SCI,IF2.896),2011,89:293–302(DOI10.1007/s00253-010-2876-9)
Year2010
[12]ZhenyuWang,MellisaLy,FumingZhang,WeihongZhong,AmySuen,JonathanS.Dordick,RobertJ.Linhardt,E.coliK5fermentationandthepreparationofheparosan,BiotechnologyandBioengineering(SCI,IF3.377),2010,107:964-973DOI10.1002/bit.22898
[11]ZhongWH*,ZhuCJ,ShuM.,SunKD,ZhaoL,WangC,YeZJ,ChenJM,NicotinedegradationbynewlyisolatedPseudomonassp.ZUTSKDinthereconstitutedtobaccoprocessfromtobaccowastes,BioresourceTechnology(SCI,IF4.45),2010,101,6935-6941
Year2009
[10]WHZhong*,JJFang,HGLiu,XWang,EnhancedproductionofCoQ10bynewlyisolatedSphingomonassp.ZUTEO3withacoupledfermentation-extractionprocess,JournalofIndustrialMicrobiologyandBiotechnology(SCI,IF1.919),2009,36,687-693
[9]ChenDZ,ChenJM,ZhongWH,Enhancementofmethyltert-butyletherdegradationbyadditionofreadilymetabolizableorganicsubstances,JournalofHazardousMaterials(SCI,IF4.14),2009,167:860-865
Year2008
[8]XWang,YZhang,WHZhong*,Poly-γ-glutamicacidproductionbynovelisolatedBacillussubtiliszjutzyanditsflocculatingcharacter,JournalofBiotechnology,2008,136,Supplement1,S43
[7]DZChen,JMChen,WHZhong,ZWCheng,Degradationofmethyltert-butyletherbygelimmobilizedMethylibiumpetroleiphilumPM1,BioresourceTechnology(SCI,IF4.45),2008,99:4702-4708
Year2007
[6]JMChen,DZChen,WHZhong,Biodegradationofmethyltert-butyletherbyMethylibiumpetroleiphilumPM1inpoornutritionsolution.JournalofEnvironmentalScienceandHealthPartA,2007,42(14):2123-2129
[5]WHZhong,JMChen,ZLu,DZChen,XChen,Aerobicdegradationofmethyltert-butyletherbyaProteobacteriastraininaclosedculturesystem,JournalofEnvironmentalScience(SCI,IF1.4),2007,19(1):18-22
Year2006
[4]WHZhong,JMChen,EnvironmentalBiotechnologyinChina:ProgressandProspect,BiotechnologyJournal,2006,1(11):1241-1252
[3]WHZhong,JMChen,ZLu,DZChenandXChen,Methyltert-butyletherdegradationbyapurebacteriaPM1inaclosedsystem,AbstractsofPapersoftheAmericanChemicalSociety231stNationalMeeting,Atlanta,USA,60-ENVMar.28,2006
Year2005
[2]WHZhong,PLCen,PectinaseproductionbyAspergillusnigerP-6021onCitruschangshan-huyoupeelinslurrystatefermentation,ChineseJournalofChemicalEngineering,2005,13(4):510-515
[1]WHZhong,WChen,AFRETmeasurementmethodforreactionbetweenATPandNa,K-ATPasebyconfocalmicroscope,ProceedingsofXVIIIInternationalSymposiumonBioelectrochemistryandBioenergetics,2005,Coimbra,Portugal,p207
InChinese:
[12]赵雷,严子琴,王畅,钟卫鸿*,大肠杆菌K5产肝素前体heparosan的研究进展,生物技术进展,2011,1(3):195-200
[11]XuYun,JinJing,ZhongWeihong,WuShijin,QiuLequan,ChenJianmeng,Isolation,identificationandConditionsofBacterialStraincapabletoMetabolizeHighConcentrationsofFormaldehyde,EnvironmentalScience,2010,31(10):216-221(徐云,金晶,郑重,钟卫鸿*,吴石金,邱乐泉,陈建孟.高活性高耐受甲醛降解菌株的分离鉴定及降解条件研究[J].环境科学,2010,31(10):216-221)
[10]HGLiu,JJFang,LJin,WHZhong,ZJYe,Isolation,CharacterizationandFermentationConditionofCoenzymeQ10ProducingStrainwithSolanesolasPrecursor,ActaMicrobiologicaSinica,2008,48(2)：157~163(柳华贵,方建军,金凌,钟卫鸿*,叶紫娟,茄尼醇转化高产辅酶Q10菌株的分离鉴定与发酵条件的研究,微生物学报,2008,48(2):157~163)
[9]KDSun,CJZhu,WHZhong,JMChen,ZJYe,PJLiu,QZhou,Isolationandcharacterizationofahighnicotine-degradingbacterium,Pseudomonassp.ZUTSKD,ActaScientiaeCircumstantiae,2008,28(7):1294-1301(孙柯丹,朱晨静,钟卫鸿*,等,一株尼古丁高效降解菌株的分离鉴定和降解特性,环境科学学报,2008,28(7):1294-1301)
[8]WHZhong,LZheng,JMChen,XChen,KDSun,ConditionsandIntermediateMetabolitesofMTBEDegradationbyβ-Proteobacteria,EnvironmentalScience,2006,27(12):2536-2541(钟卫鸿,路争,陈建孟,陈效,孙柯丹,β-Proteobacteria菌降解甲基叔丁基醚的条件及中间代谢产物研究,环境科学,2006,27(12):2536-2541)
[7]YRSong,WHZhong,LZheng,Applicationofmetabolicengineeringinbiosynthesisoflycopene,IndustrialMicrobiology,2006,36:60-64(宋艳绒,钟卫鸿*,路争,番茄红素代谢工程研究进展,工业微生物,2006,36:60-64)
[6]WHZhong,HRYe,JMChen,YRSong,NewMethodforSpatialStructureQuantificationofBiofilmwithGFPTaggedBacteria,EnvironmentalScience,2005,26(4):160-164(钟卫鸿,叶海仁,陈建孟,宋艳绒.应用绿色荧光蛋白基因标记细菌进行生物膜结构定量化新方法,环境科学,2005,26(4):160-164)
[5]WHZhong,JJMiao,StudyonSubmergedCultureConditionsofLipaseInhibitorProducingStrain,ActaMicrobiologicaSinica,2003,43：514~518(钟卫鸿,缪建军,脂肪酶抑制剂产生菌BacillusspLF深层发酵条件研究,微生物学报,2003,43:514-518)
[4]WHZhong,PLCen,JMa,JJTong.StudyonkineticmodelsforbatchcultivationofalkalinepectinasewithSpirillosporaspZG9901,JournalofchemicalengineeringofChineseuniversities,2002,16:311-315(钟卫鸿,岑沛霖,马骏,童景景,间歇发酵SpirillosporaspZG9901产碱性果胶酶动力学研究,高校化学工程学报,2002,16:311-315)
[3]WHZhong,PLCen,YChen,NHe,HYu,SimultaneousProductionofPectinaseandClarificationofJuicewithAspergillusnigerP-6021ImmobilizedbyPolyurethaneFoam,Mycosystem,2001,20(4):503-507(钟卫鸿,岑沛霖,陈瑶,何宁,俞昊琼,聚氨酯泡沫固定化黑曲霉P-6021可以同时产酶和澄清果汁,菌物系统(真菌学报),2001,20(4):503-505)
[2]WHZhong,QWang,PCen,StudiesonalkalinepectinaseproducingconditionsbySpirillosporaZG9901,Chinesejournalofapplied&environmentalbiology,2000,6(5):468-472(钟卫鸿,王启军,岑沛霖,SpirillosporaZG9901产碱性果胶酶发酵条件研究，应用与环境生物学报,2000,6:468-472)
[1]PWang,WHZhong,BJYu,ScreeningofstainproducingD-xylosereductase,Pharmaceuticalbiotechnology,2001,8(3):156-159(王普,钟卫鸿,虞炳钧,木糖还原酶产酶菌株的筛选,药物生物技术,2001,8(3):156～159)
Books
[1]WHZhong,LXZhang,ZFCui,ZMChen,LQQiu,THZhu,GeneEngineeringTechnology,Beijing:ChemicalIndustryPress,2007(钟卫鸿,张礼星,崔志峰,陈振明,邱乐泉,朱廷恒,基因工程技术,北京:化学工业出版社,2007)
[2]WHZhong,LXZhang,ZFCui,ZMChen,LQQiu,THZhu,StudentExperimentalGuidanceforGeneEngineeringTechnology,Beijing:ChemicalIndustryPress,2007(钟卫鸿,汪琨,邱乐泉,钱海丰,基因工程技术实验指导,北京:化学工业出版社,2007)
[3]XYZhou,ZHZhang,ZHSun,WHZhong,MBWu,EnzymeTheoryandEnzymeEngineering,Beijing:ChineseLightIndustryPress,2005(周哓云,张朝晖,孙志浩,钟卫鸿,吴绵斌,酶学原理与酶工程,北京:中国轻工业出版社,2005,302-338)
　6、发明专利：
申请公开专利：
[1]钟卫鸿王伟建,邱乐泉,方建军,钟莉,吴石金,丁羟甲苯和/或α-亚麻酸作为前体在制备辅酶Q10中的应用,201010293424.3
[2]钟卫鸿金晶邱乐泉吴石金钟莉徐云郑重陈建孟,高活性高耐受甲醛降解菌及其应用,201010204536.7
[3]钟卫鸿,方建军,柳华贵,钟莉,李炎生,李艺潇,汪新,张艾晓,一种利用鞘氨醇单胞菌发酵萃取耦合制备辅酶Q10的方法，CN200810062350.5
　　授权专利：
[1]钟卫鸿,孙柯丹,李艺潇,陈建孟,陈东之,一种菌藻混合生物降解甲基叔丁基醚的方法,专利号：ZL200710067342.5
[2]舒明;杨君;钟卫鸿;朱晨静;朱申康;朱雪娜,用于烟叶烟碱降解的假单胞菌ZCJ菌株及其筛选方法和应用,专利号:ZL200910097536.9
[3]钟卫鸿,孙柯丹,朱晨静,柳华贵,李艺潇,邱乐泉,吴石金,陈建孟等,降解尼古丁新菌株—假单胞菌ZUTSKD及其应用,专利号:ZL200710070805.3
[4]钟卫鸿,陈建孟,叶海仁,汪琨,宋艳绒,路争,用于构造生物膜的成膜菌剂及解析生物膜的方法,专利号:ZL200410093061.3
[5]钟卫鸿,柳华贵,金凌,邱乐泉,吴石金,陈建孟,孙柯丹,方建军,产辅酶Q10新菌株——鞘氨醇单胞菌ZUTE03及其应用,ZL200710070806.8
　　7、联系方式：
Tel/Fax:0571-88320739(Office)
Email:whzhong@zjut.edu.cn
(Updated,Jan2012)