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1、学历背景：浙江医科大学理学学士（1983）、医学硕士（1987）、浙江大学医学博士（1999）
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1. 通过对基因多态性和体细胞突变的研究，阐述疾病发生发展及治疗中的个体差异。\r2. 利用基因重组技术克隆表达具有生物活性的蛋白质，为生物技术新药的发现和生产作技术储备。\r3. 利用生物化学与免疫学技术研究先进诊断技术，为诊断试剂产业的发展服务。\r
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2008-01-04 14:02:26
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1、学历背景：浙江医科大学理学学士（1983）、医学硕士（1987）、浙江大学医学博士（1999）
\r2、国外学习研究经历：1993.12-1995.8 美国肯塔基大学药学院访问**** 2001.1-2002.1 美国康乃尔大学分子生物学系博士后。
\r3、工作经历：
\r1983.8-1985.8浙江省余姚丈亭卫生院药师
\r1987.8-1990.10浙江医科大学生物化学教研室助教
\r1990.10-1993.12浙江医科大学生物化学教研室讲师
\r1995.8-1998.10浙江大学医学院生物化学教研室副教授，硕士导师
\r1998.10-2003.3宁波大学医学院教授，副院长
\r2005.7-2009.5 浙江大学药学院党委 副书记
\r2005.11-2011.5 浙江大学药理毒理与生化药学研究所副所长
\r\r2003.4-2015.6 浙江大学药学院药理毒理与生化药学研究所主任，教授，博导
\r\r2015.6-现在 浙江大学药物代谢与药物分析研究所 副所长，教授，博导
\r主要论文
\r\r\rLi-Qiang Pan,Wen-Bin Zhao,Jun Lai,Ding Ding,Xiao-Yue Wei,Yang-Yang Li,Wen-Hui Liu, Xiao-Yue Yang,Ying-Chun Xu, Shu-Qing Chen. Hetero-modification of TRAIL trimer for improved drug delivery andin vivoantitumor activities. Scientific Reports2015; 5, Articlenumber:14872 , doi:10.1038\/srep14872
\rLifang Zhou, Yajing Lei, Dai Zhang, Shabbir Ahmed, Shuqing Chen. An ultra-sensitive monoclonal antibody-based enzyme-linked immunosobent assay for dibutylphthalate in human urinary. Science of the Total Environment. 2016; 541(): 570-578
\rQingpo Li,Qin Tang,Peizun Zhang,Zuhua Wang,Tiantian Zhao,Jialin Zhou,Hongrui Li, Qian Ding,Wei Li,Fuqiang Hu,Yongzhong Du,Hong Yuan,Shuqing Chen,Jianqing Gao, Jinbiao Zhan,Jian You. Human epidermal growth factor receptor-2 antibodies enhance thespecificity and anticancer activity of light-sensitive doxorubicin-labeled liposomes. Biomaterials, 2015; 57(): 1–11. IF= 8.557
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Shuqing Chen. Polymeric-based particulate systems for delivery of therapeutic proteins. Pharmaceutical Development and Technology. Posted online on January 8, 2015. (doi:10.3109\/**.2014.999785) IF=1.335
\rGuoqing Ying, Fangfang Zhu, Yu Yi, Jianshu Chen, Jianfeng Mei, Yanlu Zhang, Shuqing Chen. Selecting DNA aptamers for endotoxin separation. Biotechnology Letter. 2015 Aug; 37(8): 1601-5. IF=1.7
\rXiaojing Tang, Shuqing Chen.Epigenetic Regulation of Cytochrome P450 Enzymes and Clinical Implication. Current Drug Metabolism.2015;16(2):86-96. IF=3.487
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Muhammad Tariq, Shuqing Chen. Development of therapeutic proteins: advances and challenges. Turkish Journal of Biology. 2015; 39(3): 343-58. IF=1.343
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Shuqing Chen. Natural and synthetic polymers as drug carriers for delivery of therapeutic proteins. Polymer Reviews. 2015; 55(x):xxx-xxx. IF= 6.156 http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/**.2014.995806
\rYajing Lei, Xiaoyan Yao, Dai Zhang, Lifang Zhou, Weixian Lu, Shuqing Chen. Investigation of the salbutamol residue level in human urinary samples by a sensitive direct competitive ELISA. Analytical Methods. 2015; 7(13): 5635 – 5640. IF=1.937
\rGuoqing Ying, Yanlu Zhang, Guoqiang Tang, Shuqing Chen. Functions of thymic stromal lymphopoietin in non-allergic diseases. Cellular Immunology. 2015; 295: 144–149. IF=1.8
\rYajing Lei,Xiaoyi Li,Muhammad Sajid Hamid Akash,Lifang Zhou,Xiaojing Tang, Weixing Shi,Zhiming Liu,Shuqing Chen. Development of analytical method for ultrasensitive detection of Salbutamol utilizing DNA labeled-immunoprobe. Journal of Pharmaceutical and Biomedical Analysis. 2015; 107 (march 25): 204–208. IF= 2.829
\rChen Wu, Zhaoming Wang, Xin Song, Xiao-shan Feng, Christian C Abnet, Jie He, Nan Hu, Xian-Bo Zuo, Wen Tan, Qimin Zhan, Zhibin Hu, Zhonghu He, Weihua Jia, Yifeng Zhou, Kai Yu, Xiao-ou Shu, Jian-min Yuan, Wei Zheng, Xue-ke Zhao, She-gan Gao, Zhi-Qing Yuan, Fu-You Zhou, Zong-min Fan, Ji-li Cui, Hong-li Lin, Xue-na Han, Bei Li, Xi Chen, Sanford M Dawsey, Linda Liao, Maxwell P Lee, Ti Ding, You-lin Qiao, Zhihua Liu, Yu Liu, Dianke Yu, Jiang Chang, Lixuan Wei, Yu-tang Gao, Woon-Puay Koh, Yong-Bing Xiang, Ze-Zhong Tang, Jin-Hu Fan, Jing-Jing Han, Sheng-li Zhou, Peng Zhang, Dong-Yun Zhang, Yuan Yuan, Ying Huang, Chunling Liu, Kan Zhai, Yan Qiao, Guangfu Jin, Chuanhai Guo, Jianhua Fu, Xiaoping Miao, Changdong Lu, Haijun Yang, Chaoyu Wang, William A Wheeler, Mitchell Gail, Meredith Yeager, Jeff Yuenger, Er-tao Guo, Ai-li Li, Wei Zhang, Xue-min Li, Liang-dan Sun, Bao-gen Ma, Yan Li, Sa Tang, Xiu-Qing Peng, Jing Liu, Amy Hutchinson, Kevin Jacobs, Carol Giffen, Laurie Burdette, Joseph F Fraumeni Jr, Hongbing Shen, Yang Ke, Yixin Zeng, Tangchun Wu, Peter Kraft, Charles C Chung, Margaret A Tucker, Zhi-chao Hou, Ya-li Liu, Yan-long Hu, Yu Liu, Li Wang, Guo Yuan, Li-sha Chen, Xiao Liu, Teng Ma, Hui Meng, Li Sun, Xin-min Li, Xiu-min Li, Jian-wei Ku, Ying-Fa Zhou, Liu-Qin Yang, Zhou Wang, Yin Li, Qirenwang Qige, Wen-Jun Yang, Guang-Yan Lei, Long-Qi Chen, En-min Li, Ling Yuan, Wen-Bin Yue, Ran Wang, Lu-wen Wang, Xue-Ping Fan, Fang-Heng Zhu, Wei-Xing Zhao, Yi-min Mao, Mei Zhang, Guo-lan Xing, Ji-lin Li, Min Han, Jing-li Ren, Bin Liu, Shu-wei Ren, Qing-Peng Kong, Feng Li, Ilyar Sheyhidin, Wu Wei, Yan-Rui Zhang, Chang-Wei Feng, Jin Wang, Yu-Hua Yang, Hong-Zhang Hao, Qi-de Bao, Bao-chi Liu, Ai-Qun Wu, Dong Xie, Wan-cai Yang, Liang Wang, Xiao-Hang Zhao, Shu-Qing Chen, Jun-Yan Hong, Xue-Jun Zhang, Neal D Freedman, Alisa M Goldstein, Dongxin Lin, Philip R Taylor, Li-dong Wang & Stephen J Chanock. Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. Nature Genetics.2014; 46(9): 1001-6. IF=29.648
\rYajing Lei, Qian Zhang, Lizheng Fang, Muhammad Sajid Hamid Akash, Kanwal Rehman, Zhiming Liu, Weixing Shi, Shuqing Chen. Development and comparison of two competitive ELISAs for estimation of cotinine in human exposed to environmental tobacco smoke. Drug Testing and Analysis. 2014; 6(10): 1020–1027. IF= 3.27
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Shuqing Chen. Spice Plant Allium cepa: Dietary Supplement for Treatment of Type 2 Diabetes Mellitus. Nutrition.2014 Oct; 30(10): 1128-37. IF= 2.859
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Shuqing Chen. Pluronic F127-Based Thermosensitive Gels for Delivery of Therapeutic Proteins and Peptides. Polymer Reviews. 2014; 54(4): 573-597. IF= 7.794
\rPei He, Furong Wang, Yan Jiang, Yi Zhong, Yongfei Lan, Shuqing Chen. Altered proteome profile of placenta from women with intrahepatic cholestasis of pregnancy. International Journal of Gynecology and Obstetrics. 2014; 126 (3): 256-9.IF=1.563
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Shuqing Chen. Effects of Coffee on Type 2 Diabetes Mellitus. Nutrition. 2014; 30(7): 755-63. IF= 2.859
\rYajing Lei, Wenhui Liu, Lizheng Fang, Muhammad Sajid Hamid Akash, Kanwal Rehman, Hua Narenmandura, Weixing Shi, Weixian Lu, Yingchun Xu, Shuqing Chen. Assessment of urinary concentration of cotinine in Chinese pregnant women exposed to environmental tobacco smoke. Chinese Science Bulletin. 2014; May. 59(13): 1386-1391. IF= 1.319
\rHai-Bin Wang, Hong-Jian Zheng, Zhao Wang, Hua Bai, John F. Carpenter, Shu-Qing Chen, Wei-Jie Fang. Formation of Protein Sub-Visible Particles during Vacuum Degassing of Etanercept Solutions. International Journal of Biological Macromolecules. 2014; 66:151-7. IF=3.096
\rMin Wu, Wenhui Liu, Guanghui Yang, Dengke Yu, Dianhai Lin, Hongying Sun, Shu-Qing Chen. Engineering ofaPichiapastorisexpressionsystem for high-level secretion of HSA\/GHfusionprotein. AppliedBiochemistryandBiotechnology. 2014 Jan, 172(5): 2400-11. IF= 1.893
\rZhaohui Li, Qian Zhang, Haibing Wang, Yanan Zhang, Ding Ding, Liqiang Pan, David Miao, Shi Xu, Chen Zhang, Peihua Luo, Hua Naranmandura, Shuqing Chen. Preclinical Studies of Targeted Therapies for CD20-Positive B Lymphoid Malignancies by Ofatumumab Conjugated with Auristatin. Investigational New Drugs. 2014 Feb; 32(1): 75-86. IF=3.498
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun，Shu-Qing Chen. Assessment of Release Kinetics, Stability and Polymer Interaction of PF127-Based thermosensitive gel of Interleukin-1 Receptor Antagonist. Pharmaceutical Development and Technology. 2014; 19(3): 278-284. IF=1.333
\rBin Chen, Muhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun, Shuqing Chen. Expression and bioactivity analysis of staphylococcal enterotoxin G and staphylococcal enterotoxin I. Pharmaceutical Biology. 2014; 52(1): 8-13. IF=1.337
\rYajing Lei, Lizheng Fang, Muhammad Sajid Hamid Akash, Zhiming Liu, Weixing Shi, Shuqing Chen. Development and comparison of two competitive ELISAs for detection of bisphenol A in human urine. Analytical Methods. 2013; 5, 6106-6113.IF=1.855
\rYajing Lei, Lizheng Fang, Muhammad Sajid Hamid Akash, Kanwal Rehman, Zhiming Liu, Weixing Shi, Shuqing Chen. Estimation of Urinary Concentration of Aflatoxin M1 in Chinese Pregnant Women. Journal of Food Science. 2013; Nov; 78(11): T1835-8. IF=1.775, TOP
\rLi-Qiang Pan, Hai-Bin Wang, Jun Lai, Ying-Chun Xu, Chen Zhang, Shu-Qing Chen. Site-specific PEGylation of a mutated-cysteine residue and its effect on tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL). Biomaterials. 2013 Dec; 34(36): 9115-23. IF= 7.604. TOP
\rShao-qing Ni, Wei Zhao, Jue Wang, Su Zeng, Shu-qing Chen, Evelyne Jacqz-Aigrain and Zheng-yan Zhao. Population pharmacokinetics of ciclosporin in Chinese children with aplastic anemia: effects of weight, renal function and stanozolol administration. Acta Pharmacologica Sinica, 2013; 34: 969–975; IF=2.354
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Shuqing Chen. IL-1Ra and its delivery strategies: inserting the association in perspective. Pharmaceutical Research, 2013 Nov; 30(11): 2951-66. IF=4.742
\rLi-Qiang Pan, Hai-Bin Wang, Zhang-Ming Xie, Zhao-Hui Li, Xiao-Jing Tang, Ying-Chun Xu, Chen Zhang, Hua Naranmandura and Shu-Qing Chen. Novel Conjugation of Tumor Necrosis Factor -Related Apoptosis-Inducing Ligand (TRAIL) with Monomethyl Auristatin E for Efficient Antitumor Drug Delivery. ADVANCED MATERIALS. 2013; 25(34): 4718–4722. IF=14.829,TOP, ZJU100
\rWang Furong, Wu Min, Liu Wenhui, Shen Qi, Sun Hongying, Chen Shuqing. Expression, purification, and lipolytic activity of recombinant human serum albumin fusion proteins with one domain of human growth hormone in Pichia pastoris. Biotechnol Appl Biochem. 2013 Jul; 60(4): 405-11. IF=1.348
\rLi Qiang Pan, Zhang Ming Xie, Xiao Jing Tang, Min Wu, Fu Rong Wang, Hua Naranmandura, Shu Qing Chen. Engineering and refolding of a novel trimeric fusion protein TRAIL-collagen XVIII NC1. Applied Microbiology and Biotechnology. 2013 Aug; 97(16):7253-64. IF=3.689,TOP
\rMin Wu, Qi Shen, Yong Yang, Sheng Zhang, Wen Qu, Jing Chen, Hongying Sun, Shuqing Chen. Disruption of YPS1 and PEP4 genes reduces proteolytic degradation of secreted HSA\/PTH in Pichia pastoris GS115. Journal of Industrial Microbiology & Biotechnology. 2013; 40(6): 589-599. IF= 2.321
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun，Shu-Qing Chen. Cross-species amino acids sequence comparison and computational docking of human IL-1Ra and rat IL-1Ra on rat receptor. Journal of Proteomics & Bioinformatics. 2013; 6(2): 38-42. IF=2.2
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun，Shu-Qing Chen. Sustained delivery of IL-1Ra from PF127-gel reduces hyperglycemia in diabetic GK-Rats.PLOS ONE.2013; 8(2):e55925. IF=4.09
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun，Shu-Qing Chen. Interleukin-1 receptor antagonist improves normoglycemia and insulin sensitivity in diabetic Goto-Kakizaki-Rats. European Journal of Pharmacology. 2013; 701: 87-95. IF=2.592,TOP
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Shu-Qing Chen. Role of Inflammatory Mechanisms in pathogenesis of Type 2 Diabetes Mellitus. Journal of Cellular Biochemistry. 2013;114:525-531. IF= 3.062
\rYajing Lei, Shujie Zhang, Lizheng Fang, Muhammad Sajid Hamid Akash, Weixing Shi, Kedan Sun, Yingchun Xu,Shuqing Chen. A sensitive and specific enzyme immunoassay for detecting tartrazine in human urinary samples. Analytical Methods. 2013; 5: 925–930 IF=1.855
\rQi Shen, Min Wu, Hai-Bin Wang, Hua Naranmandura & Shu-Qing Chen.The Effect of Gene Copy Number and Co-Expression of Chaperone on Production of Albumin Fusion Proteins in Pichia Pastoris. Applied Microbiology and Biotechnology. 2012; 96:763–772. IF=3.425, TOP
\rMuhammad Sajid Hamid Akash, Kanwal Rehman, Ni Li, Jian-Qing Gao, Hongying Sun and Shuqing Chen. Sustained delivery of IL-1Ra from Pluronic F127-based thermosensitive gel prolongs its therapeutic potentials. Pharmaceutical Research. 2012; 29(12):3475-3485. IF=4.742，不俗论文
\rXuan Chen, Li Qiang Pan, Hua Naranmandura, Su Zeng, Shu Qing Chen. Influence of various polymorphic variants of cytochrome P450 oxidoreductase (POR) on drug metabolic activity of CYP3A4 and CYP2B6. PLoS ONE 2012；7(6): e38495. IF=4.411
\rHua Naranmandura, Xuan Chen, Mariko Tanaka, Wen Wen Wang, Kanwal Rehman, Shi Xu, Zhe Chen, Shu Qing Chen, Noriyuki Suzuki. Release of Apoptotic Cytochrome c from Mitochondria by Dimethylarsinous Acid (DMAIII) Occurs Through Interaction with Voltage Dependent Anion Channel (VDAC) In Vitro. Toxicological Sciences. 2012; 128(1): 137-146. April 26. IF=5.1
\rLM Kong, MR Qian, HH Hu, SY Xu, LS Yu, HD Jiang, SQ Chen, S Zeng. Comparison of catalytical activity and stereoselectivity between the recombinant human cytochrome P450 2D6.1 and 2D6.10. Pharmazie 2012; 67: 440–447. IF=0.994
\rAbnet CC, Wang Z,Song X, Hu N, Zhou FY, Freedman ND, Li XM, Yu K, Shu XO, Yuan JM, Zheng W, Dawsey SM, Liao LM, Lee MP, Ding T, Qiao YL, Gao YT, Koh WP, Xiang YB, Tang ZZ, Fan JH, Chung CC, Wang C, Wheeler W, Yeager M, Yuenger J, Hutchinson A, Jacobs KB, Giffen CA, Burdett L, Fraumeni JF Jr, Tucker MA, Chow WH, Zhao XK, Li JM, Li AL, Sun LD, Wei W, Li JL, Zhang P, Li HL, Cui WY, Wang WP, Liu ZC, Yang X, Fu WJ, Cui JL, Lin HL, Zhu WL, Liu M, Chen X, Chen J, Guo L, Han JJ, Zhou SL, Huang J, Wu Y, Yuan C, Huang J, Ji AF, Kul JW, Fan ZM, Wang JP, Zhang DY, Zhang LQ, Zhang W, Chen YF, Ren JL, Li XM, Dong JC, Xing GL, Guo ZG, Yang JX, Mao YM, Yuan Y, Guo ET, Zhang W, Hou ZC, Liu J, Li Y, Tang S, Chang J, Peng XQ, Han M, Yin WL, Liu YL, Hu YL, Liu Y, Yang LQ, Zhu FG, Yang XF, Feng XS, Wang Z, Li Y, Gao SG, Liu HL, Yuan L, Jin Y, Zhang YR, Sheyhidin I, Li F, Chen BP, Ren SW, Liu B, Li D, Zhang GF, Yue WB, Feng CW, Qige Q, Zhao JT, Yang WJ, Lei GY, Chen LQ, Li EM, Xu LY, Wu ZY, Bao ZQ, Chen JL, Li XC, Zhuang X, Zhou YF, Zuo XB, Dong ZM, Wang LW, Fan XP, Wang J, Zhou Q, Ma GS, Zhang QX, Liu H, Jian XY, Lian SY, Wang JS, Chang FB, Lu CD, Miao JJ, Chen ZG, Wang R, Guo M, Fan ZL, Tao P, Liu TJ, Wei JC, Kong QP, Fan L, Wang XZ, Gao FS, Wang TY, Xie D, Wang L, Chen SQ, Yang WC, Hong JY, Wang L, Qiu SL, Goldstein AM, Yuan ZQ, Chanock SJ, Zhang XJ, Taylor PR, Wang LD. Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: A meta-analysis of genome-wide association studies. Hum Mol Genet. 2012 May 1;21(9):2132-41. IF=8.14
\rTing Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing Chen. An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population. Drug Metabolism and Disposition. 2012 Feb 7. 2012 40 (5): 847-51. IF=3.77, TOP
\rMuhammad Sajid Hamid Akash, Qi Shen, Kanwal Rehman, Shuqing Chen. Interleukin-1 Receptor Antagonist: A New Therapy for Type 2 Diabetes Mellitus. Journal of Pharmaceutical Sciences. 2012; 101(5): 1647-1658. IF=3.03，不俗论文
\rDing Ding, Peng Huang, Yingqiu Pan, Shuqing Chen. Gene detection of Staphylococcal enterotoxins in production strain of Staphylococcin injection and superantigenic activity of rSEK and rSEQ. World Journal of Microbiology and Biotechnology. World J Microbiol Biotechnol. 2011; 27(12): 2957-2967. IF=1.214
\rChunna Yu, Xiaojuan Chai, Lushan Yu, Shuqing Chen, Su Zeng. Identification of novel pregnane X receptor activators from traditional Chinese medicines. Journal of Ethnopharmacology. 2011, Jun 14;136(1):137-43. IF=2.32, TOP
\rXie S, Chen Y, Chen S, Zeng S. Structure-metabolism relationships for the glucuronidation of flavonoids by UGT1A3 and UGT1A9. J Pharm Pharmacol. 2011 Feb;63(2):297-304. IF=1.918
\rLi-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, Xin Song, Yan Jin, Jiang-Man Li, Guo-Qiang Kong, Hong Qi, Juan Cui, Lian-Qun Zhang, Jie-Zhi Yang, Ji-Lin Li, Xing-Chuan Li, Jing-Li Ren, Zhi-Cai Liu, Wen-Jun Gao, Ling Yuan, Wu Wei, Yan-Rui Zhang, Wei-Peng Wang, Ilyar Sheyhidin, Feng Li, Bao-Ping Chen, Shu-Wei Ren, Bin Liu, Dan Li, Jian-Wei Ku, Zong-Min Fan, Sheng-Li Zhou, Zhi-Gang Guo, Xue-Ke Zhao, Na Liu, Yong-Hong Ai, Fang-Fang Shen, Wen-Yan Cui, Shuang Song, Tao Guo, Jing Huang, Chao Yuan, Jia Huang, Yue Wu, Wen-Bin Yue, Chang-Wei Feng, Hong-Lei Li, Yan Wang, Jin-Ya Tian, Yue Lu, Yi Yuan, Wen-Liang Zhu, Min Liu, Wen-Jing Fu, Xia Yang, Han-Jing Wang, Suo-Li Han, Jie Chen, Min Han, Hai-Yan Wang, Peng Zhang, Xiu-Min Li, Jin-Cheng Dong, Guo-Lan Xing, Ran Wang, Ming Guo, Zhi-Wei Chang, Hai-Lin Liu, Li Guo, Zhi-Qing Yuan, Hai Liu, Qin Lu, Liu-Qin Yang, Fu-Guo Zhu, Xiu-Feng Yang, Xiao-Shan Feng, Zhou Wang, Yin Li, She-Gan Gao, Qirenwang Qige, Long-Tang Bai, Wen-Jun Yang, Guang-Yan Lei, Zhong-Ying Shen, Long-Qi Chen, En-Min Li, Li-Yan Xu, Zhi-Yong Wu, Wei-Ke Cao, Jian-Po Wang, Zhi-Qin Bao, Ji-Li Chen, Guang-Cheng Ding, Xiang Zhuang, Ying-Fa Zhou, Hou-Feng Zheng, Zheng Zhang, Xian-Bo Zuo, Zi-Ming Dong, Dong-Mei Fan, Xin He, Jin Wang, Qi Zhou, Qin-Xian Zhang, Xin-Ying Jiao, Shi-Yong Lian, Ai-Fang Ji, Xiao-Mei Lu, Jin-Sheng Wang, Fu-Bao Chang, Chang-Dong Lu, Zhi-Guo Chen, Jian-Jun Miao, Zeng-Lin Fan, Ruo-Bai Lin, Tai-Jiang Liu, Jin-Chang Wei, Qing-Peng Kong, Yu Lan, Yu-Jing Fan, Fu-Sheng Gao, Tian-Yun Wang, Dong Xie, Shu-Qing Chen, Wan-Cai Yang, Jun-Yan Hong, Liang Wang, Song-Liang Qiu, Zhi-Ming Cai , Xue-Jun Zhang. Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nature Genetics. 2010, 42, 759–63. IF=36.377
\rKun Ma, Minxin Hu, Meng Xie, Haijun Shen, Liyan Qiu, Weimin Fan, Hongying Sun, Shuqing Chen, Yi Jin. Investigation of polyethylenimine-graftedtri- amcinolone acetonide as nucleus-targeting gene delivery systems. The Journal of Gene Medicine. 2010; 12: 669–680. IF=3.079
\rYakun Chen, Yong Tang, Shuqing Chen, Daotai Nie. Regulation of Drug Resistance by Human Pregnane X Receptor in Breast Cancer. Cancer Biology & Therapy. 2009 Jul 1; 8(13): 1265-72. IF=2.907
\rDing Ding, Peng Huang, Hongying Sun, Qiao Xue, Yingqiu Pan, Shuqing Chen. Identification of Protein Components and Establishment of Quantitative Immunoassay for SEC2 in Staphylococcin Injection. Journal of Pharmaceutical and Biomedical Analysis, 2009; 50: 79-85 IF=2.723
\rChunna Yu, Shanshan Ye, Hongying Sun, Yao Liu, Lingbo Gao, Chaofeng Shen, Shuqing Chen, Su Zeng. PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA. Chemico-Biological Interactions. 2009; 177: 58-64 IF=3.310
\rNi S, Wang X, Wang J, Lu S, Zeng S, Zhao Z, Yu L, Chen S. Effects of intrauterine undernutrition on the expression of CYP3A23\/3A1, PXR, CAR and HNF4alpha in neonate rats. Biopharm Drug Dispos. 2008 Dec 4;29(9):501-510. IF=1.39
\rYakun Chen, Shenggu Xie, Shuqing Chen and Su Zeng. Glucuronidation of flavonoids by recombinant UGT1A3 and UGT1A9. Biochemical Pharmacology. 2008; 76: 416-25 IF=4.889
\r\r
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chenshuqing@zju.edu.cn
address
药学院221室
research
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1094
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47eeab**e891ca0242ac110003
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2021-01-25 00:13:36
content
1、学历背景：浙江医科大学理学学士（1983）、医学硕士（1987）、浙江大学医学博士（1999）
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个人简介
