基本信息
姓名: 陈伟 性别: 男
学历: 研究生 学位: 博士(硕导)
职称: 研究员 出生年份: 1982-10
博导类型: 博导专业: —— 博导学院: ——
硕导类型: 学术型 硕导专业: 微生物与生化药学 硕导学院: 生命科学学院
Email: viogro@163.com 联系电话:
研究方向: 肿瘤耐药和肿瘤免疫
工作单位: 浙江省立同德医院
发表论文
1、miR-223 overexpression inhibits doxorubicin- induced autophagy by targeting FOXO3a and reverses chemoresistance in hepatocellular carcinoma cells.,Yue Zhou, Enjiang Chen, Yuexiao Tang,Chai Kequn and Wei Chen,Cell Death and Disease,SCI,2019-10,Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhejiang University, School of Medicine, 310009 Hangzhou, Zhejiang, China,二区,5.959,1-13

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2、miR-137 Alleviates Doxorubicin Resistance in Breast Cancer Through Inhibition of Epithelial-Mesenchymal Transition by Targeting DUSP4. ,Du Feiya, Yu Ling, Wu Ying, Wang huqian,Yu Liu, Chen Wei,Cell Death and Disease,SCI,2019-10,Department of Orthopaedics, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China,二区,5.959,1-10

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3、The long noncoding RNA TUG1 is required for TGF-β/TWIST1/EMT-mediated metastasis in colorectal cancer cells,Shen Xuning , Hu Xiu , Chen Wei,Cell Death and Disease,SCI,2020-01,Department of Gastrointestinal Surgery, Affiliated Hospital of Jiaxing College, Jiaxing, Zhejiang, China,二区,5.959,1-10

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4、LncRNA MALAT1 silencing protects against cerebral ischemia-reperfusion injury through miR-145 to regulate AQP4.,Wang Hongwei, Zheng Xiaoxiao, Jin Jing,Wu Ying and Chen Wei,Journal of Biomedical Science,SCI,2020-03,Department of anesthesiology, Tongde hospital of Zhejiang Province, Hangzhou 310012, Zhejiang, China.,三区,5.203,1-12

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5、Chimeric peptide supramolecular nanoparticles for plectin-1 targeted miRNA-9 delivery in pancreatic cancer.,Wu Ying, Tang Yuexiao, Xie Shangzhi,Chai Kequn and Wei Chen,Theranostics,SCI,2020-01,Cancer Institute of Integrated Traditional Chinese and Western Medicine, Zhejiang Academy of Traditional Chinese Medicine, Tongde Hospital of Zhejiang province, Hangzhou 310012, China,一区,8.063,1151-1165

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6、Cenicriviroc ameliorates the severity of graft-versus-host disease through inhibition of CCR5 in a rat model of liver transplantation,Minhuan Li, Chenglin Lu, Hao Zhu,Wei Chen,Am J Transl Res,SCI,2019-06,Center of Pathology and Clinical Laboratory, Sir Run Run Hospital, Nanjing Medical University, Nanjing 211100, Jiangsu Province, China,三区,3.266,3438-3449

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7、Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression,Chuxiao Shao, Chaoyong Tu, Xiangdong Cheng,Chuxiao Shao，Kequn Chai, Wei Chen,International Journal of Biological Sciences,SCI,2019-04,Department of Hepatopancreatobiliary Surgery, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, School of Medicine, Lishui, Zhejiang 323000, P.R. China,二区,4.067,1020-1029

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8、COUP‐TFII promotes epithelial‐mesenchymal transition by inhibiting miR‐34a expression in colorectal cancer,YING BAO, YONGLIANG LU,WEI CHEN and XIANG WANG,INTERNATIONAL JOURNAL OF ONCOLOGY,SCI,2019-01,First Affiliated Hospital, Huzhou University, The First People's Hospital of Huzhou,二区,3.571,1337-1344

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9、miR-9 Enhances the Chemosensitivity of AML Cells to Daunorubicin by Targeting the EIF5A2/MCL-1 Axis,Yanhui Li,Wei Chen, Fei Xue,International Journal of Biological Sciences,SCI,2019-01,Department of Hemotology, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Henan University People’s Hospital, Zhengzhou, PR China,二区,4.067,579-586

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10、MicroRNA‐212 suppresses nonsmall lung cancer invasion and migration by regulating ubiquitin‐specific protease‐9,Wei Chen and Yuye Huang ,Kequn Chai and Wei Chen,J Cell Biochem,SCI,2019-04,Department of Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang, People’s Repubic of China,三区,3.448,6482-6489

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11、AMPK-related kinase 5 (ARK5) enhances gemcitabine resistance in pancreatic carcinoma by inducing epithelial-mesenchymal transition,Xiaoguang Wang, Zhengwei Song,Wei Chen, Zhengxiang Zhong,Am J Transl Res,SCI,2018-12,Department of Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang, People’s Repubic of China,三区,3.266,4095-4106

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12、eIF5A2 regulates the resistance of gastric cancer cells to cisplatin via induction of EMT,Jiancheng Sun, Zhiyuan Xu,Wei Chen, Xiangdong Cheng,Am J Transl Res,SCI,2018-12,First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, P.R. China;,三区,3.266,4269-4279

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13、USP9X inhibition improves gemcitabine sensitivity in pancreatic cancer by inhibiting autophagy.,Tao Ma, Wei Chen, Xiao Zhi, Hao Liu,Tingbo Liang,Cancer Letters,SCI,2018-11,Department of Hepatobiliary and Pancreatic Surgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310009, China,一区,6.508,129-138

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14、Bortezomib enhances the therapeutic efficacy of dasatinib by promoting c-KIT internalization-induced apoptosis in gastrointestinal stromal tumor cells.,Ying Dong, Chao Liang,Wei Chen,Cancer Letters,SCI,2015-05,Department of Oncology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China,一区,6.508,137-146

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15、Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis.,Long-Yun Ye, Wei Chen, Xue-Li Bai,Ting-Bo Liang,Cancer Research,SCI,1899-12-31 00:00,Department of Oncology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China,一区,8.378,818-830

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16、PTPRB promotes metastasis of colorectal carcinoma via inducing epithelial-mesenchymal transition.,Xingyue Weng, Wei Chen,Shu Zheng,Cell Death and Disease,SCI,2019-04,Cancer Institute, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Hangzhou, Zhejiang, China,二区,5.959,

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17、Delivery of miR-212 by chimeric peptide-condensed supramolecular nanoparticles enhances the sensitivity of pancreatic ductal adenocarcinoma to doxorubicin.,Wei Chen, Yue Zhou, Xiao Zhi,Tingbo Liang,Biomaterials,SCI,2019-02,Department of Hepatobiliary and Pancreatic Surgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China,一区,10.273,590-600

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科研项目
1、青年拔尖人才,陈伟,浙江省立同德医院,浙江省卫生计生委,浙江省“****”,2019-01,2021-12,80,80

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2、2018年度浙江省卫生创新人才培养对象,陈伟,浙江省立同德医院,浙江省卫生健康委员会,2018年度浙江省卫生创新人才培养对象,2019-01,2023-12,40,40

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3、HOTAIR 调控自噬发生在胃肠道间质瘤伊马替尼耐药中的作用研究,陈伟,浙江省立同德医院,浙江省卫生健康委员会,浙江省医药卫生科技计划省部共建计划,2019-01,2021-12,15,15

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4、多肽核酸自组装纳米靶向颗粒在胰腺癌免疫治疗中的应用价值研究,陈伟,浙江省中医药研究院,省自然科学基金,****项目,2019-11,2023-12,80,80

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5、益胃饮调控胃癌肝脏转移前灶形成从而抑制肝转移的作用及其机制研究,陈伟,浙江省立同德医院,浙江省中管局,浙江省中医药科技计划重点项目,2019-09,2022-08,15,15

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6、一种新型免疫检查靶点CD112R在肿瘤免疫中的作用及机制研究,陈伟,浙江省中医药研究院,国家基金委,国家自然科学基金面上项目,2019-08,2023-12,51,51

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7、 FOXO3a 在肝癌诱导肿瘤相关巨噬细胞生成中的作用研究,陈伟,浙江大学,国家基金委,国家自然科学基金青年科学基金项目,2014-01,2016-12,23,23

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8、纳米靶向调控肝癌组织内肿瘤相关巨噬细胞表型的技术研发及应用价值研究,陈伟,浙江大学,科技部,国家高技术研究发展计划(863 计划),2014-01,2016-12,100,100

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科研成果
1、肝癌微环境与癌细胞耐药关系机制及其治疗策略研究,梁廷波,梁廷波; 白雪莉; 陈伟; 章琦; 杨菲,浙江大学医学院附属第二医院,浙江省人民政府,自然科学省部一等奖,2017-01

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2、肝癌微环境与癌细胞耐药关系机制及其治疗策略研究,梁廷波,梁廷波; 白雪莉; 陈伟; 章琦; 胡奇达; 马涛; 梁超; 支枭; 刘昊; 叶龙云; 魏涛; 周悦; 陈炜; 傅琦涵; 闻良,浙江大学医学院附属第二医院,浙江省卫生和计划生育委员会,浙江省医药卫生科技一等奖,2016-04

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3、器官移植中靶器官功能损伤及其保护的研究,梁廷波,梁廷波; 白雪莉; 龚渭华; 陈伟; 马涛; 夏雪峰; 梁靓; 薛飞; 徐国栋; 张匀; 王林燕; 刘昊; 吴懿; 胡金灵; 黄品同,浙江大学医学院附属第二医院,中华人民共和国教育部,科技进步省部一等奖,2014-01

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个人信息