基本信息
姓名：唐云平
籍贯：浙江湖州
职称：副研究员
学术职衔：硕士生导师
院系：浙江海洋大学食品与医药学院药学系
通讯地址：浙江省舟山市定海区临城街道中国舟山海洋科学城A12幢1101


学习/工作经历
2003.09-2007.06 浙江工商大学 生物工程 本科
2007.09-2010.06 浙江工商大学 生物化工 硕士
2011.09-2016.06 浙江大学 生物化工 博士
2016.09-至今 任教于浙江海洋大学食品与医药学院药学系、浙江省海洋生物医用制品工程技术研究中心
2018.08-2020.12 浙江工业大学 生物化工 博士后
研究方向
1. 海洋活性物质免疫调节活性
2. 海洋活性物质护肝活性
3. 肠道菌群
教学情况
承担本科生课程《制药工艺学》、《蛋白质与酶工程》
指导本科生毕业设计和课程设计
指导国家级大学生创新创业训练计划项目1项
指导浙江省大学生新苗人才计划1项
指导1名研究生获国家奖学金
科研项目
1. 国家青年自然科学基金，基于MAPK/NF-κB和PI3K/Akt/NF-κB信号通路的海洋多肽CSP免疫调节机制研究，项目编号NO.**，2019.1.1-2021.12.31，课题主持人。
2. 浙江省博士后择优项目，羰基还原酶的挖掘及催化制备氯醇类化合物的关键技术，2019.06-2022.06，课题主持人
3. 企业横向课题，羰基还原酶的挖掘及催化制备氯醇类化合物的关键技术，长兴制药股份有限公司，2017.09-2019.12，课题主持人。
发表论文（第一作者或通讯作者）
2020年
1. Shuoqi Jiang, Zhuangwei Zhang , FangFang Huang, Zuisu Yang, Fangmiao Yu, Yunping Tang*, Guofang Ding*. Protective Effect of Low Molecular Weight Peptides from Solenocera crassicornis Head against Cyclophosphamide-Induced Nephrotoxicity in Mice via the Keap1/Nrf2 Pathway. Antioxidants. 2020, 9(8):745. (2020 IF 5.041).
2. Shuoqi Jiang, Zhuangwei Zhang, Fangmiao Yu, Zhoufeng Zhang, Zuisu Yang,
Yunping Tang*, Guofang Ding*. Ameliorative effect of low molecular weight peptides from the head of red shrimp (Solenocera crassicornis) against cyclophosphamide-induced hepatotoxicity in mice. Journal of Functional Foods, 2020, 72:104085. (2020 IF 3.701).
3. Baogui Xua, Lei Yea, Yunping Tang*, Jiawen Zheng, Xiaoxiao Tian, Yuxia Yang, Zuisu Yang*. Preparation and purification of an immunoregulatory peptide from Stolephorus chinensis of the East Sea of China. Process Biochemistry, 2020, 98: 151-159. (2020 IF 2.952).
4. Xinhui Lin, Fei Yang, Ju Huang, Su Jiang, Yunping Tang*, Jianrong Li*. Ameliorate effect of pyrroloquinoline quinone against cyclophosphamide-induced nephrotoxicity by activating the Nrf2 pathway and inhibiting the NLRP3 pathway.
Life Sciences, 2020, 256:117901. (2020 IF 3.647)
5. YafengZhou, QiaojunZhao, ShuyaoZhou, FandiQue, GuifangLi, and YunpingTang*. Efficient biosynthesis of (R)-2-chloro-1-(2, 4-dichlorophenyl) ethanol using a mutant short-chain dehydrogenase from Novosphingobium aromaticivorans. Tetrahedron Letters, 2020. (2020 IF 2.275).
6. Fangmiao Yu*, Kang He, Xiaoze Dong, Zhuangwei Zhang, Fenglei Wang, Yunping Tang*, Yan Chen, Guofang Ding. Immunomodulatory activity of low molecular-weight peptides from Nibea japonica skin in cyclophosphamide-induced immunosuppressed mice. Journal of Functional Foods, 2020, 68: 103888. (2020 IF 3.701).
7. Xiaoxia Jiang, Yafeng Zhou, Yun Zhang*, Diying Tian, Su Jiang, YunpingTang*. Hepatoprotective effect of pyrroloquinoline quinone against alcoholic liver injury through activating Nrf2-mediated antioxidant and inhibiting TLR4-mediated inflammation responses. Process Biochemistry, 2020, 92: 303-312. (2020 IF 2.952).
8. Yunping Tang*, Yafeng Zhou, Qiaojun Zhao, Qiaoling Zhao, Zhao Wang*. Enzymatic synthesis of an orlistat intermediate using a mutant short-chain dehydrogenase from Novosphingobium aromaticivorans. Process Biochemistry, 2020. 95:235-241. (2020 IF 2.952).
9. Xiaoxia Jiang, Zhexin Ren, Biying Zhao, Shuyao Zhou, Xiaoguo Ying*, Yunping Tang*. Ameliorating Effect of Pentadecapeptide Derived from Cyclina sinensis on Cyclophosphamide-Induced Nephrotoxicity. Marine Drugs, 2020, 18(9): 462. (2020 IF 4.073).
2019年
1. Yingyue Chen, Huoxi Jin, Fei Yang, Shujie Jin, Chenjuan Liu, Liukai Zhang, Ju Huang, Shiguang Wang, Zhongyong Yan, Xuwei Cai, Rui Zhao, Fangmiao Yu, Zuisu Yang, Guofang Ding, Yunping Tang*. Physicochemical, antioxidant properties of giant croaker (Nibea japonica) swim bladders collagen and wound healing evaluation. International Journal of Biological Macromolecules, 2019, 138: 483-491. (2019 IF 4.784).
2. Nan Chen, Yinyue Chen, Yunping Tang*, Qiaoling Zhao, Chenjuan Liu, Wenwen Niu, Peiyang Huang, Fangmiao Yu, Zuisu Yang, Guofang Ding. Efficient synthesis of (S)-2-chloro-1-(2, 4-dichlorophenyl) ethanol using a tetrad mutant alcohol dehydrogenase from Lactobacillus kefir, Process Biochemistry, 2019, 85:78-83. (2019 IF 2.883).
3. Chuhong Zong, Xu Zhang, Fei Yang, Yafeng Zhou, Nan Chen, Zuisu Yang, Guofang Ding, Fangmiao Yu* and Yunping Tang*. Biotransformation of a Crizotinib intermediate using a mutant alcohol dehydrogenase of Lactobacillus kefir coupled with glucose dehydrogenase. Preparative Biochemistry & Biotechnology 2019, 49(6):578-583. (2019 IF 1.117).
4. Xiaoxia Jiang, Fei Yang, Qiaojun Zhao, Diying Tian, Yunping Tang*. Protective effects of pentadecapeptide derived from Cyclaina sinensis against cyclophosphamide-induced hepatotoxicity. Biochemical and Biophysical Research Communications, 2019, 520(2):392-398. (2019 IF 2.705).
5. Fei Yang, Shujie Jin, Yunping Tang*. Marine Collagen Peptides Promote Cell Proliferation of NIH-3T3 Fibroblasts via NF-κB Signaling Pathway. Molecules, 2019, 24(22), 4201. (2019 IF3.06).
6. Fangmiao Yu*, Zhuangwei Zhang, Shengwang Ye, Xiaoxia Hong, Huoxi Jin, Fangfang Huang, Zuisu Yang, Yunping Tang*, Yan Chen, Guofang Ding. Immunoenhancement effects of pentadecapeptide derived from Cyclina sinensis on immune-deficient mice induced by Cyclophosphamide. Journal of Functional Foods, 2019 (60):103408. (2019 IF 3.197).
7. Shuoqi Jiang, Yinglu Jia, Yunping Tang*, Die Zheng, Xingbiao Han, Fangmiao Yu, Yan Chen, Fangfang Huang, Zuisu Yang and Guofang Ding*. Anti-Proliferation activity of a decapeptide from Perinereies aibuhitensis toward human lung cancer H1299 cells. Marine Drugs 2019, 17(2), 122. (2019 IF 3.772).
8. Yanan Chen, Yunping Tang*, Yanhua Tang, Zuisu Yang and Guofang Ding*. Serine protease from Nereis virens inhibits H1299 lung cancer cell proliferation via the PI3K/AKT/mTOR pathway. Marine Drugs 2019, 17(6), 366. (2019 IF 3.772)
9. Xinhui Lin, Yinyue Chen, Huoxi Jin, Qiaoling Zhao, Chenjuan Liu, Renwei Li, Fangmiao Yu, Yan Chen*, Fangfang Huang, Zuisu Yang, Guofang Ding and Yunping Tang*. Collagen extracted from bigeye tuna (Thunnus obesus) skin by isoelectric precipitation: physicochemical properties, proliferation, and migration activities. Marine Drugs, 2019, 17, 261. (2019 IF 3.772).
10. Wei Li, Shengwang Ye, Zhuangwei Zhang, Jiachao Tang, Huoxi Jin, Fangfang Huang, Zuisu Yang, Yunping Tang*, Yan Chen, Guofang Ding and Fangmiao Yu*. Purification and characterization of a novel pentadecapeptide from protein hydrolysates of Cyclina sinensis and its immunomodulatory effects on RAW264.7 cells. Marine Drugs, 2019, 17, 30-45. (2019 IF 3.772).
2018年
1. Yunping Tang, Shujie Jin, Xiaoyan Li, Xiaojuan Li, Xuyang Hu, Yan Chen, Fangfang Huang, Zuisu Yang, Fangmiao Yu* and Guofang Ding*. Physicochemical properties and biocompatibility evaluation of collagen from the skin of giant croaker (Nibea japonica). Marine Drugs, 2018, 16, 222-232. (2018 IF 4.379).
2. Xiaojuan Li, Yunping Tang*, Fangmiao Yu, Yu Sun, Fangfang Huang, Yan Chen, Zuisu Yang and Guofang Ding*. Inhibition of prostate cancer DU-145 cells proliferation by Anthopleura anjunae oligopeptide (YVPGP) via PI3K/AKT/mTOR signaling pathway. Marine Drugs, 2018, 16, 325-340. (2018 IF 4.379).
3. Fangmiao Yu, Chuhong Zong, Shujie Jin, Jiawen Zheng, Nan Chen, Ju Huang, Yan Chen, Fangfang Huang, Zuisu Yang, Yunping Tang* and Guofang Ding, Optimization of extraction conditions and characterization of pepsin-solubilised collagen from skin of giant croaker (Nibea japonica). Marine Drugs, 2018, 16, 29-40. (2018 IF 4.379).
4. Yunping Tang*, Guomei Zhang, Zheng Wang, Dan Liu, Linglu Zhang, Yafeng Zhou, Ju Huang, Fangmiao Yu, Zuisu Yang and Guofang Ding^*, Efficient synthesis of a (S)-fluoxetine intermediate using carbonyl reductase coupled with glucose dehydrogenase. Bioresource Technology, 2018, 250: 457-463. (2018 IF: 5.807).