浙江农林大学动物科技学院导师教师师资介绍简介-浙江农林大学

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吴艳萍博士/讲师
吴艳萍，博士，动物科技学院·动物医学院专任教师，主要从事微生态制剂在动物肠道健康方向的研究与应用，目前以第一作者（含共一）在Journal of Cellular Physiology, Frontiers in Microbiology, Microorganisms等杂志发表7篇SCI论文，主持和参与多项国家和省部级科研项目。

通讯地址
教育背景
工作经历
课程教学
获奖荣誉
研究方向
科研项目
发表论文
授权专利

通讯地址浙江省杭州市临安区武肃街666号学2-414
邮编：311300
E-mail:ypwu@zafu.edu.cn
电话/传真：

教育背景博士 (2014.09-2019.06): 浙江大学动物科学学院动物营养与饲料科学专业

博士生联合培养 (2017.11-2018.11):美国宾夕法尼亚大学兽医学院病原生物学系

学士 (2010.06-2014.09): 南京农业大学动物科技学院动物科学专业

工作经历 2019.07-至今：浙江农林大学动物科技学院，讲师

课程教学 1.动物生物化学实验（本科）

获奖荣誉 1.浙江农林大学动科动医学院“教坛新秀”和 “科研先进个人”（2020）

2.浙江省优秀毕业生（2019）

3.浙江大学优秀毕业生（2019）

4.动物微生态年会优秀论文三等奖（2018）

5.中澳农业与食品创新论坛优秀口头报告奖（2017）

研究方向 1.益生菌改善动物肠道健康的机理研究

2.解析益生菌的抗菌分子机制

3.动物肠道微生态

科研项目 1.基于猪肠上皮细胞自噬解析植物乳杆菌的抗菌分子机制（**，2021.1-2023.12，24万元）国家自然科学基金青年科学基金项目主持

2.基于群体感应信号探究植物乳杆菌的抗菌作用机理（Q21C170001，2021.1-2023.12，10万元）浙江省自然科学基金探索项目主持

3.植物乳杆菌体外抑制猪沙门氏菌的作用机理研究（2020FR003，2020.4-2022.4，5万元）浙江农林大学科研发展基金项目主持

4.益生芽孢杆菌对断奶仔猪自噬的影响及其缓解氧化应激的分子机理（**，2017.1-2020.12，60万元）国家自然科学基金面上项目参加

5.基于肠上皮细胞外泌体调控巨噬细胞极化的机理研究（**，2018.1-2020.12，24万元）国家自然科学基金青年科学基金项目参加

发表论文 SCI收录:

2020

1.Yanping Wu#, Qiaoyun Hu#, Ruchika Dehinwal, Alexey Rakov, Nicholas Grams, Erin C. Clemens, Jennifer Hofmann, Iruka N. Okeke, Dieter M. Schifferli*. The not so good, the bad and the ugly: Differential bacterial adhesion and invasion mediated by Salmonella PagN allelic variants. Microorganisms, 2020, 8: 489.

2019

1.Yanping Wu, Baikui Wang, Han Xu, Li Tang, Yali Li, Li Gong, Yang Wang*, Weifen Li*. Probiotic Bacillus attenuates oxidative stress- induced intestinal injury via p38-mediated autophagy[J]. Frontiers in Microbiology, 2019. (Accepted)

2.Yanping Wu, Li Tang, Baikui Wang, Qiming Sun, Pengwei Zhao, Weifen Li*. The role of autophagy in maintaining intestinal mucosal barrier[J]. Journal of Cellular Physiology, 2019.

3.Yanping Wu, Baikui Wang, Zhonghua Zeng, Rongrong Liu, Li Tang, Li Gong*, Weifen Li*. Effects of probiotics Lactobacillus plantarum Lac16 and PaeniBacillus polymyxa BSC10 on intestinal barrier function, antioxidative capacity, apoptosis, immune response and biochemical parameters in broilers[J]. Poultry Science, 2019.

4.Yanping Wu, Han Xu, Xuefang Cao, Rongrong Liu, Li Tang, Zhonghua Zeng, Weifen Li*. Bacillus amyloliquefaciens Ameliorates H2O2-Induced Oxidative Damage by Regulating Transporters, Tight Junctions, and Apoptosis Gene Expression in Cell Line IPEC-1[J]. Probiotics and antimicrobial proteins, 2019: 1-8.

5.Yang Wang, Yanping Wu, Baikui Wang, Han Xu, Xiaoqiang Mei, Xiaogang Xu, Xiaoping Zhang, Jiajia Ni and Weifen Li*. Bacillus amyloliquefaciens SC06 Protects Mice Against High-Fat Diet-Induced Obesity and Liver Injury via Regulating Host Metabolism and Gut Microbiota[J]. Frontiers in Microbiology, 2019, 10: 1161.

6.Yang Wang, Li Gong, Yanping Wu, Zhiwen Cui, Yongqiang Wang, Yi Huang, Xiaoping Zhang, Wei-fen Li*. Oral administration of Lactobacillus rhamnosus GG to newborn piglets augments gut barrier function in pre-weaning piglets[J]. Journal of Zhejiang University-SCIENCE B, 2019, 20(2): 180-192.

2018

1.Shenglan Hu, Xuefang Cao, Yanping Wu, Xiaoqiang Mei, Han Xu, Yang Wang, Xiaoping Zhang,Li Gong, Weifen Li*. Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets[J]. Frontiers in Microbiology, 2018.10.22, 9: 2427~2436

2.Xiaogang Xu, Li Gong, Baikui Wang, Yanping Wu, Yang Wang, Xiaoqiang Mei, Han Xu, Li Tang, Rongrong Liu, Zhonghua Zeng, Yulong Mao* and Weifen Li*. Glycyrrhizin attenuates Salmonella enterica serovar Typhimurium infection: new insights into its protective mechanism[J]. Frontiers in immunology, 2018, 9: 2321.

2017

1.Yanping Wu, Yang Wang, Hai Zou, Baikui Wang, Qiming Sun, Aikun Fu, Yuanyuan Wang, Yibing Wang, Xiaogang Xu1* and Weifen Li*. Probiotic Bacillus amyloliquefaciens SC06 induces autophagy to protect against pathogens in macrophages[J]. Frontiers in microbiology, 2017, 8: 469.

2.Yang Wang, Yanping Wu (co-first author), Yibing Wang, Aikun Fu, Li Gong, Weifen Li*, Yali Li*. Bacillus amyloliquefaciens SC06 alleviates the oxidative stress of IPEC-1 via modulating Nrf2/Keap1 signaling pathway and decreasing ROS production[J]. Applied microbiology and biotechnology, 2017, 101(7): 3015-3026.

3.Yang Wang, Yanping Wu, Yuanyuan Wang, Han Xu, Xiaoqiang Mei, Dongyou Yu, Yibing Wang* and Weifen Li *. Antioxidant Properties of Probiotic Bacteria[J]. Nutrients, 2017, 9(5): 521.

4.Yang Wang, Yanping Wu, Baikui Wang, Xuefang Cao, Aikun Fu, Yali Li* & Weifen Li*. Effects of probiotic Bacillusas a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets[J]. AMB Express, 2017, 7(1): 52.

5.Aikun Fu, Yang Wang, Yanping Wu, Hongliang Chen, Shasha Zheng, Yali Li, Xin Xu, Weifen Li*. Echinacea purpurea Extract Polarizes M1 Macrophages in Murine Bone Marrow‐Derived Macrophages Through the Activation of JNK[J]. Journal of cellular biochemistry, 2017, 118(9): 2664-2671.

6.Yali Li, Yuanyuan Wang, Yanping Wu, Baikui Wang, Xi Chen, Xin Xu, Hongliang Chen, Weifen Li*, Xiaogang Xu. Echinacea pupurea extracts promote murine dendritic cell maturation by activation of JNK, p38 MAPK and NF-κB pathways[J]. Developmental and Comparative Immunology, 2017,73：21-26.

7.Luoqin Fu, Yali Li, Aikun Fu, Yanping Wu, Yuanyuan Wang, Shenglan Hu, Weifen Li*.Pidotimod exacerbates allergic pulmonary infection in an OVA mouse model of asthma. Molecular medicine reports, 2017, 16(4), 4151-4158.

8.Li Gong, Qin Huang, Aikun Fu, YanPing Wu, Yali Li, Xiaogang Xu, Yi Huang, Dongyou Yu, Weifen Li*. Spores of two probiotic Bacillus species enhance cellular immunity in BALB/C mice[J]. Canadian journal of microbiology, 2017, 64(1): 41-48

2015

1.Xiangyu He, Yanping Wu, Min Cai, Chunlong Mu, Weihong Luo, Yanfen Cheng*, Weiyun Zhu*. The effect of increased atmospheric temperature and CO2 concentration during crop growth on the chemical composition and in vitro rumen fermentation characteristics of wheat straw[J]. Journal of animal science and biotechnology, 2015, 6(1): 46.

中文期刊:

2016

1.吴艳萍, 王阳, 曹雪芳, 李雅丽, 李卫芬*. 氧化应激与自噬[J], 动物营养学报, 2016, 28（9）: 2673-2680

2012

1.吴艳萍, 张仕仪, 施一姗, 周岩民*. 天然沸石对大肠杆菌K88的吸附作用研究[J], 非金属矿, 2013, 36 (5): 30-41.

会议论文:

2019

1.Yanping Wu, Baikui Wang, Han Xu, Li Tang, Weifen Li*. Probiotic Bacillus attenuates oxidative stress-induced intestine injury: new insights into its protective mechanism. Joint the International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health. Oral Presentation. Congress center, Prague, Czech Republic, June 16-22, 2019.

2017

1.Yanping Wu, Hai Zou, Baikui Wang, Qiming Sun, Weifen Li*. Probiotic Bacillus amyloliquefaciens SC06 induces Autophagy to Protect against Pathogens in Macrophages. Joint the Australia-China Conference on Science,Technology and Innovation Forum on Agricultural and Food Science. Oral Presentation. The University of Western Australia, Perth, Australia, February 1-7, 2017.

授权专利李卫芬，王佰魁，俞国乔，吴艳萍，毛予龙，黄怡，付爱坤，王阳，王一冰. 预防鸡坏死性肠炎的植物乳杆菌及其应用, 2019-11-05,中国,ZL6.4.