个人信息
姓　　名: 郑明华 性　　別: 男 院　　系: 第一临床医学院（信息与工程学院）、附属第一医院
行政职务: 科副主任 职　　称: 副主任医师 学术兼职:
导师类别: 专业型硕导 任硕导年月: 2016-12-30 任博导年月:
从事专业1: 从事专业2: 办公电话:
学　　历: 博士研究生 学　　位: 博士 E-mail: zhengmh@wmu.edu.cn
毕业院校: 温州医科大学 毕业专业: 毕业时间:
人才类别:





本人从事的主要研究方向的特点、意义及其水平:2016年12月开始至今，致力于脂肪肝平台的建设。历时四年多，温州脂肪肝的临床与研究均取得了较大的进展，在国际上享有一定的声誉。2020年，作为中国大陆2位代表之一，参与2项脂肪肝国际专家共识的发表（一项为脂肪肝更名国际专家共识；一项为亚太区代谢相关脂肪性肝病诊疗共识）。在Hanson临床科研2020年大数据分析中，位列中国肝病/消化科最活跃的医生科学家第二。在2021年3月全球****库新发布的全国感染性疾病领域专家国际论文学术影响力百强中，排名13。发表论文可查阅：https://www.researchgate.net/profile/Ming_Hua_Zheng，目前团队可用经费150万。

参与获得2016年度教育部高等学校科学研究优秀成果奖（科学技术）二等奖、中华医学科技奖一等奖、浙江省科技进步一等奖、浙江省医药卫生科技一等奖、温州市科技进步一等奖。

2017年获温州市青年拔尖人才称号，2016年入选浙江省卫生厅高层次创新人才培养人选。2012年入选温州市“新世纪551人才工程”第二层次培养人选。2010、2012、2014年三度荣获浙江省科协“育才工程”。2017年入选温州市科协“育才工程”。2012年入选温州医科大学青年骨干教师；2013年入选温州医科大学教坛新秀。主要业绩已被美国著名的科学家与工程技术人员名人传记《MARQUIS WHO'S WHO》著作所收录（2011-2012第八版）。温州医科大学附属第一医院青年学科带头人。2011年获温州市青年岗位能手荣誉称号。2012年获香港大学李嘉诚医学院郑裕彤奖助金。2011年奥地利格拉茨医科大学访问****。2012年香港玛丽医院访问****。



学术团体任职情况:中国研究型医院学会肝病学分会全国委员，中国研究型医院学会肝病学分会脂肪肝学组委员，全国疑难及重症肝病攻关协作组全国委员，全国肝胆病咨询专家，中国中医药信息研究会临床研究分会理事，中华预防医学会循证预防医学专业委员会循证医学方法学组委员，中国医师协会循证医学专业委员会全国青年委员，中国中西医结合学会循证医学专业委员会全国青年委员，浙江省医学会肝病学分会委员，浙江省医学会临床流行病学与循证医学分会青年委员会副主任委员，浙江省数理医学会肝病学分会常务委员，温州市医学会感染病肝病分会青年委员会副主任委员。欧洲肝脏研究协会会员


招生专业情况
招生专业1研究方向1招生专业2研究方向2招生专业3研究方向3招生备注
内科学 传染病 传染病医疗技能训练与研究

近五年发表期刊论文
论文名称期刊名称卷期 期刊类型影响因子本人排序
AKI-CLIF-SOFA: a novel prognostic score for critically ill cirrhotic patients with acute kidney injury. Aging (Albany NY) 9(1)
Ratio of Conjugated Chenodeoxycholic to Muricholic Acids is Associated with Severity of Nonalcoholic Steatohepatitis Obesity (Silver Spring) 27 (12)
A girl with left wrist deformity. BMJ
A young man with recurrent limb shaking. BMJ
National incidence of autoimmune liver diseases and its relationship with the human development index. Oncotarget 7(29)
Systematic review with network meta-analysis: Comparative efficacy of oral nucleos(t)ide analogues for the prevention of chemotherapy-induced hepatitis B virus reactivation Oncotarget 7(21)
Remodeling the model for end-stage liver disease for predicting mortality risk in critically ill patients with cirrhosis and acute kidney injury Hepatol Commun 1(8)
Elevation of plateletcrit increasing the risk of non-alcoholic fatty liver disease development in female adults: A large population-based study. Clin Chim Acta
Development of a prognostic nomogram for cirrhotic patients with upper gastrointestinal bleeding Eur J Gastroenterol Hepatol 29(10)
Comparative efficacy of vasoconstrictor therapies for type 1 hepatorenal syndrome: a network meta-analysis. Expert Rev Gastroenterol Hepatol 11(11)
A painful wrist after a fall BMJ
Quick chronic liver failure-sequential organ failure assessment: an easy-to-use scoring model for predicting mortality risk in critically ill cirrhosis patients Eur J Gastroenterol Hepatol 29(6)
Abnormality in a fetus on ultrasound. BMJ
Synergistic increase in cardiovascular risk in diabetes mellitus with nonalcoholic fatty liver disease: a meta-analysis. Eur J Gastroenterol Hepatol
Stratified alpha-fetoprotein pattern accurately predicts mortality in patients with acute-on-chronic hepatitis B liver failure Expert Rev Gastroenterol Hepatol 12(3)
NAFL screening score: A basic score identifying ultrasound-diagnosed non-alcoholic fatty liver. Clin Chim Acta
Scoring model to predict outcome in critically ill cirrhotic patients with acute respiratory failure: comparison with MELD scoring models and CLIF-SOFA score. Expert Rev Gastroenterol Hepatol 11(9)
Stratified Platelet-to-lymphocyte Ratio: A Novel Target for Prognostic Prediction of Hepatocellular Carcinoma after Curative Liver Resection J Clin Transl Hepatol 5(1)
The NAFL Risk Score: A simple scoring model to predict 4-y risk for non-alcoholic fatty liver Clin Chim Acta
Acute circulatory failure-chronic liver failure-sequential organ failure assessment score: a novel scoring model for mortality risk prediction in critically ill cirrhotic patients with acute circulatory failure Eur J Gastroenterol Hepatol 29(4)
Association of low-density lipoprotein cholesterol within the normal range and NAFLD in the non-obese Chinese population: a cross-sectional and longitudinal study. BMJ Open 6(12)
Establishment and Validation of GV-SAPS II Scoring System for Non-Diabetic Critically Ill Patients PLoS One 11(11)
A girl with an abnormal gait BMJ
Systematic Review with Network Meta-Analysis: Antidiabetic Medication and Risk of Hepatocellular Carcinoma. Sci Rep
Comparative efficacy of oral nucleotide analogues for the prophylaxis of hepatitis B virus recurrence after liver transplantation: a network meta-analysis. Expert Rev Anti Infect The 14(10)
A neonate with dyspnoea. BMJ.
Targeting endoplasmic reticulum stress in liver disease Expert Rev Gastroenterol Hepatol 10(9)
A boy with a sac-like protrusion at the occipital region BMJ
Preoperative platelet to lymphocyte ratio is a valuable prognostic biomarker in patients with colorectal cancer. Oncotarget 7(18)
Systematic Review and Network Meta-Analysis of Randomized Controlled Trials: Comparative Effectiveness and Safety of Direct-Acting Antiviral Agents for Treatment-Naive Hepatitis C Genotype 1 Medicine (Baltimore) 95(9)
Systematic review with network meta-analysis: statins and risk of hepatocellular carcinoma Oncotarget. 7(16)
Successful Treatment of Scrub Typhus-Associated Hemophagocytic Lymphohistiocytosis With Chloramphenicol: Report of 3 Pediatric Cases and Literature Review Medicine (Baltimore) 95(8)
Parabolic relationship between sex-specific serum high sensitive C reactive protein and non-alcoholic fatty liver disease in Chinese adults: a large population-based study. Oncotarget 7(12)
Nasal NK/T cell lymphoma presents with long-term nasal blockage and fever: a rare case report and literature review. Oncotarget 7(8)
Increased levels of low-density lipoprotein cholesterol within the normal range as a risk factor for nonalcoholic fatty liver disease. Oncotarget 7(5)
Kidney bioengineering in regenerative medicine: An emerging therapy for kidney disease Cytotherapy 18(2)
Methimazole-induced cholestatic hepatitis: two cases report and literature review. Oncotarget 7(4)
Serum uric acid: a new therapeutic target for nonalcoholic fatty liver disease. Expert Opin Ther Targets 20(3)
N(6) -methyladenosine Reader Protein Ythdc2 Suppresses Liver Steatosis via Regulation of mRNA Stability of Lipogenic Genes Hepatology
Homeostatic model assessment of insulin resistance closely related to lobular inflammation in nonalcoholic fatty liver disease Eur J Gastroenterol Hepatol 32 (1)
PNPLA3 Polymorphism Influences The Association Between High-Normal Tsh Level And Nash In Euthyroid Adults With Biopsy-Proven Nafld Diabetes Metab
Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae Cell Metab 30 (4)
Higher liver stiffness scores are associated with early kidney dysfunction in patients with histologically proven non-cirrhotic NAFLD Diabetes Metab
Effect of PNPLA3 polymorphism on diagnostic performance of various non-invasive markers for diagnosing and staging NAFLD J Gastroenterol Hepatol
A Simpler Diagnostic Formula for Screening Nonalcoholic Fatty Liver Disease Clin Biochem 64
Expert recommendations on standardized diagnosis and treatment for fatty liver disease in China (2019 revised edition) Zhonghua Gan Zang Bing Za Zhi 27 (10)
A systematic review and a dose-response meta-analysis of coffee dose and nonalcoholic fatty liver disease Clin Nutr 38 (6)
Combined and sequential non-invasive approach to diagnosing non-alcoholic steatohepatitis in patients with non-alcoholic fatty liver disease and persistently normal alanine aminotransferase levels BMJ Open Diabetes Res Care 8（1）
PNPLA3 rs738409 Is Associated With Renal Glomerular and Tubular Injury in NAFLD Patients With Persistently Normal ALT Levels Liver Int 40 (1)
FibroScan-AST (FAST) Score for the Non-Invasive Identification of Patients With Non-Alcoholic Steatohepatitis With Significant Activity and Fibrosis: A Prospective Derivation and Global Validation Study Lancet Gastroenterol Hepatol 5 (4)
Development and Validation of Hepamet Fibrosis Scoring System-A Simple, Noninvasive Test to Identify Patients With Nonalcoholic Fatty Liver Disease With Advanced Fibrosis Clin Gastroenterol Hepatol 18 (1)
Individualized risk prediction of significant fibrosis in non-alcoholic fatty liver disease using a novel nomogram United European Gastroenterol J 7 (8)
Serum alkaline phosphatase, a risk factor for non-alcoholic fatty liver, but only for women in their 30s and 40s: evidence from a large cohort study Expert Rev Gastroenterol Hepatol 11(3)


出版专著教材情况
著作名称著作类型出版社出版时间排名
Meta分析软件应用与实例解析 专著 人民卫生出版社 2013-05-01 -1
感染性疾病临床短期教程 译著 天津科技翻译出版公司 2011-01-01 -1
感染病学：临床病例解析(翻译版) 译著 人民卫生出版社 2017-05-01 -1
赢在论文（术篇） 译著 中国协和医科大学出版社 2010-05-01 -1
胃肠病学：临床病例解析(翻译版) 译著 人民卫生出版社 2016-06-01 -1
病毒性肝炎——困惑与挑战(翻译版) 译著 人民卫生出版社 2011-04-01 -1
肝脏病学热点辩论:专家点评(翻译版) 译著 人民卫生出版社 2015-03-01 -1
赢在论文 软件篇 专著 中国协和医科大学出版社 2011-07-01 -1
病学热点辩论专家点评 译著 人民卫生出版社 2015-03-01 -1
检验与临床的沟通--案例分析200例 专著 人民卫生出版社 2011-02-01 -1
制定医疗决策——医生指南(翻译版) 译著 人民卫生出版社 2011-09-01 -1
Sherlock肝胆病学(翻译版） 译著 人民卫生出版社 2014-05-01 -1
肝脏病学 临床病例解析 译著 人民卫生出版社 2013-07-01 -1
朔伊尔肝脏活检病理解读 译著 人民卫生出版社 2017-05-01 -1
慢性肝衰竭：机制与治疗 译著 人民卫生出版社 2012-06-01 -1
论文写作助手：EndNote 一点通 专著 人民卫生出版社 2008-09-01 -1
医生该如何思考：临床决策与医学实践（翻译版） 译著 人民卫生出版社 2010-01-01 -1
如何成为好医生第18版 译著 人民军医出版社 2013-06-01 -1

成果获奖情况
奖项名称奖项级别颁奖部门颁奖时间证书号排名
浙江省科学技术进步奖 其他 浙江省人民政府 2014-12-01 1
温州市科学技术进步奖 其他 温州市人民政府 2014-11-01 1
浙江省医药卫生科技奖 其他 浙江省卫生厅 2014-05-01 1
浙江省自然科学学术奖 其他 浙江省科协 2012-12-01 1
中华医学科技奖 其他 中华医学会 2017-01-01 1
温州市哲学社会科学优秀成果奖 其他 温州市人民政府 2012-03-01 1
浙江省高校科研成果奖 其他 浙江省教育厅 2011-11-01 1
青年研究****奖 其他 亚太肝脏研究学会 2012-12-01 1
温州市自然科学优秀论文奖 其他 温州市人民政府 2013-10-01 1
温州市自然科学优秀论文奖 其他 温州市人民政府 2011-12-01 1

近五年完成的科研项目
项目名称任务来源完成形式完成日期鉴定验收单位主要结论排名
FGF-21通过Sirt-1途径对酒精诱导肝脏脂肪堆积改善作用的机制研究 国家自然科学基金 2018-12-31 1
S100家族A11在非酒精性脂肪性肝炎的作用及机制研究 2024-12-31 1

目前承担的主要项目
项目名称项目类型项目来源起讫时间项目经费本人承担任务
FGF-21通过Sirt-1途径对酒精诱导肝脏脂肪堆积改善作用的机制研究 青年项目 国家自然科学基金 2016-01-01 17
S100家族A11在非酒精性脂肪性肝炎的作用及机制研究 面上项目 国家自然科学基金 2021-01-01