吴艳青
生环学院-生命科学研究院
Email: yqwu220946@yeah.net
手机号码：**


个人简介：博士，讲师，硕士生导师，温州大学新湖青年-伊利康项目获得者。从事糖尿病并发症方向研究究，重点探究糖尿病对认知功能障碍和脊髓损伤等神经损伤修复的影响。目前，已在国际著名学术期刊Diabetes, Nature Communition, Biomaterials, Cell Communication and Signaling和J Neurotrauma等发表SCI论文40余篇，论文引用539次（其中第一作者或通讯作者SCI论文21篇，SCI 2区以上16篇，H指数15）；目前主持/参与糖尿病神经病变方向等10余项；担任Am J obstet Gynecol等多个期刊杂志的审稿人。

科研项目
[1] 国家自然科学基金项目：高糖对脊髓损伤修复的影响及糖尿病合并脊髓损伤治疗的研究，2019.01.01-2021.12.30，主持。
[2] 浙江省自然科学基金青年科学基金项目：FGF1对糖尿病认知功能障碍的作用及相关机制研究，2018.01.01-2020.12.30，主持。
[3] 国家自然科学基金面上项目：骨髓源性单核细胞募集联合GA疫苗治疗实验性阿尔茨海默病的研究，2019.01.01-2022.12.30，参与。
[4] 国家自然科学基金面上项目：Foxo3a介导的自噬信号通路对糖尿病认知功能障碍的调控机制研究，2019.01.01-2022.12.30，参与。

代表论文
[1] Wu Y, Wang F, et al. Cellular stress, excessive apoptosis and the effect of metformin in a mouse model of type 2 diabetic embryopathy. Diabetes. 2015, 64(7):2526-2536. (SCI IF =8.47, 1区Top)
[2] Wu Y, Wang F, et al. Curcumin ameliorates high glucose- induced neural tube defects by suppressing cellular stress and apoptosis. Am J obstet Gynecol. 2015, 212(6):802.e1-8. (SCI IF=4.7, 2区)
[3] Wu Y, Ye L, et al. Autophagy activation is associated with neuroprotection in diabetes-asscociated cognitive decline. Aging and Disease. 2019. 10(4)：1233-1245 (SCI IF=5.06, 2区)
[4] Wu Y, Wu C, Ye L, et al. Exogenous fibroblast growth factor 1 ameliorates diabetes-induced cognitive decline via coordinately regulating PI3K/AKT signaling and PERK signaling. Cell Communication and Signaling. 2020,18:81. (SCI IF=5.11, 2区)
[5] Wu Y, Yuan Y, Wu C, et al. The reciprocal causation of ASK1-JNK1/2 pathway and endoplasmic reticulum stress in diabetes-induced cognitive decline. Frontiers in Cell and Developmental Biology. 2020 (SCI IF=5.2, 2区)
[6] Wu Y, Li Y, et al. Diabetes Induces Abnormal Ovarian Function via Triggering Apoptosis of Granulose Cells and Suppressing Ovarian Angiogenesis. International Journal of Biological Sciences. 2017, 13:1297-1308. (SCI IF=3.873, 2区)
[7] Wu Y, Li Y, Jiang T,et al. Reduction of cellular stress is essential for Fibroblast growth factor 1 treatment for diabetic nephropathy. Journal of Cellular and Molecular Medicine. 2018,22(12):6294-6303. (SCI IF=4.499, 2区)
[8] Wu Y, Jia G, et al. Fibroblast growth factor 1 ameliorates diabetes-induced splenomegaly via suppressing inflammation and oxidative stress.Biochemical and Biophysical Research Communications. 2020 Jul 23;528(2):249-255. (SCI IF=2.297, 3区)




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