主持项目：

浙江省基础公益研究项目，2019/1-2021/12
浙江省“钱江人才”项目，2019/1-2020/12
国家自然科学青年基金项目，2018/01-2020/12
温州市科技局项目，2018/01-2019/12
浙江省教育厅项目，2017/10-2019/10




获奖和荣誉
2020年温州大学伊利康青年****
2018年 浙江省“钱江人才”
2018年 温州市“特支计划青年拔尖人才”

热忱欢迎感兴趣的化学、材料、医学、药学、生物学等相关本科生和研究生加入！



发表论文：
[32] Yang, Y.#; Zhang, Q.#; Zhang, J.; Chen, A.; Chen, Y.; Li, S.; Ye, M.; Xuan, X.; Li, X.; He, H.*; Wu, J.* Natural pollen extract for photothermal therapy. Mater. Design., 2021, 202, 109573.



[31] Wu, J.#; Zhu, J.#; Wu, Q.#; An, Y.; Wang, K.; Xuan, T.; Zhang, J.; Song, W.; He, H.*; Song, L.; Zheng, J.*; Xiao, J.* Mussel-Inspired Surface Immobilization of Heparin on Magnetic Nanoparticles for Enhanced Wound Repair via Sustained Release of a Growth Factor and M2 Macrophage Polarization. ACS Appl. Mater. Interfaces, 2021, 13, 2230-2244.



[30] Xiao, Z.#, Zheng, X.#, An, Y., Wang, K., Zhang, J., He, H.*, Wu, J.*, Zwitterionic hydrogel for sustained release of growth factors to enhance wound healing, Biomater. Sci., 2021, 9, 882-891.



[29]Xiao, J#., Zhou, Y#., Ye, M., An, Y., Wang, K., Wu, Q., Song, L., Zhang, J., He, H.*, Zhang, Q., Wu, J.*, Freeze-Thawing Chitosan/Ions Hydrogel Coated Gauzes Releasing Multiple Metal Ions on Demand for Improved Infected Wound Healing, Adv. Healthcare. Mater., 2020, **.




[28] Li, S.#; Chen, A.#; Chen, Y.; Yang, Y.; Zhang, Q.; Luo, S.; Ye, M.; Zhou, Y.; An, Y.; Huang, W.; Xuan, T.; Pan, Y.; Xuan, X.; He, H.*; Wu, J.* Lotus Leaf Inspired Antiadhesive andAntibacterial Gauze for Enhanced Infected Dermal Wound Regeneration.Chem. Eng. J., 2020, 402, 126202.





[27] Chen, Y.#; Ye, M.#; Song, L.; Zhang, J.; Yang, Y.; Luo, S.; Lin, M.; Zhang, Q.; Li, S.; Zhou, Y.; Chen, A.; An, Y.; Huang, W.; Xuan, T.; Gu, Y.; He, H.*; Wu, J.*; Li, X. Piezoelectric and Photothermal Dual Functional Film for Enhanced Dermal Wound Regeneration via Upregulation of Hsp90 and HIF-1α. Appl. Mater. Today,2020, 20, 100756.



[26] Chen, A.#; An, Y.#; Huang, W.; Xuan, T.; Zhang, Q.; Ye, M.; Luo, S.; Xuan, X.; He, H.*; Zheng, J.*; Wu, J.* Highly Water-Preserving Zwitterionic Betaine-incorporated Collagen Sponges with Anti-oxidation and Anti-inflammation for Wound Regeneration. Front. Cell Dev. Biol.,2020, 8, 491.





[25] Chen, A.; Huang, W.; Wu, L.; An, Y.; Xuan, T.; He, H.*; Ye, M.; Qi, L.; Wu, J. Bioactive ECM Mimic Hyaluronic Acid Dressing via Sustained Releasing of bFGF for Enhancing Skin Wound Healing. ACS Appl. Bio Mater., 2020, 3, 3039-3048.

[24] Hu, J.; Song, Y.; Zhang, C.; Huang, W.; Chen, A.; He, H.*; Zhang, S.; Chen, Y.; Tu, C.; Liu, J.; Xuan, X.; Chang, Y.; Zheng, J.; Wu, J. Highly Aligned Electrospun Collagen/Polycaprolactone Surgical Sutures with Sustained Release of Growth Factors for Wound Regeneration. ACS Appl. Bio Mater., 2020, 3, 965-976.

[23] Xuan, X.; Zhou, Y.; Chen, A.; Zheng, S.; An, Y.; He, H.*; Huang, W.; Chen, Y.; Yang, Y.; Li, S.; Xuan, T.; Xiao, J.; Li, X.; Wu, J*. Silver crosslinked injectable bFGF-eluting supramolecular hydrogels speed up infected wound healing. J. Mater. Chem. B,2020, 8, 1359-1370.CoverPage



[22] He, H.; Nieminen, A.-L.; Xu, P.* Bioactivatable Self-quenched Nanogel for Targeted Photodynamic Therapy. Biomater. Sci., 2019,7, 5143-5149.


[21] Wu, J.; Chen, A.; Zhou, Y.; Zheng, S.; Yang, Y.; An, Y.; Xu, K.; He, H.*; Kang, J.; Luckanagul, J. A.; Xian, M.; Xiao, J.*; Wang, Q.* Novel H2S-Releasing hydrogel for wound repair via in situ polarization of M2 macrophages. Biomaterials, 2019, 222, 119398.

[20] Li, Y.; Xiao, Z.; Zhou, Y.; Zheng, S.; An, Y.; Huang, W.; He, H.*; Yang, Y.; Li, S.; Chen, Y.; Xiao, J.*; Wu, J.* Controlling the Multiscale Network Structure of Fibers To Stimulate Wound Matrix Rebuilding by Fibroblast Differentiation. ACS Appl. Mater. Interfaces, 2019, 11, 28377-28386.




[19]He, H.; Xiao, Z.; Zhou, Y.; Chen, A.; Xuan, X.; Li, Y.; Guo, X.; Zheng, J.*; Xiao, J.*; Wu, J.* Zwitterionic poly(sulfobetaine methacrylate) hydrogels with optimal mechanical properties for improving wound healing in vivo.J. Mater. Chem. B,2019, 7,1697-1707.Cover Page

[18] Zheng, Z.; Chen, A.;He, H.*; Chen, Y.; Chen, J.; Albashari, A. A.; Li, J.; Yin, J.; He, Z.; Wang, Q.; Wu, J.; Wang, Q.; Kang, J.; Xian, M.; Wang, X.*; Xiao, J.* pH and enzyme dual-responsive release of hydrogen sulfide for disc degeneration therapy.J. Mater. Chem. B,2019,7, 611-618.

[17]He, H.; Xuan, X.; Zhang, C.; Song, Y.; Chen, S.; Gong, X.; Ren, B.; Zheng, J.*; Wu, J.* Simple Thermal Pretreatment Strategy to Tune Mechanical and Antifouling Properties of Zwitterionic Hydrogels.Langmuir,2019,35, 1828-1836.



[16] Ye, Q.; Wu, Y.; Wu, J.; Zou, S.; Al-Zaazaai, A. A.; Zhang, H.; Shi, H.; Xie, L.; Liu, Y.; Xu, K.; He, H.; Zhang, F.; Ji, Y.; He, Y.; Xiao, J.* Neural Stem Cells Expressing bFGF Reduce Brain Damage and Restore Sensorimotor Function after Neonatal Hypoxia-Ischemia.Cell Physiol. Biochem,2018,45, 108-118.
[15] Wu, J.; Xiao, Z.; Chen, A.;He, H.*; He, C.; Shuai, X.; Li, X.; Chen, S.; Zhang, Y.; Ren, B.; Zheng, J.*; Xiao, J.* Sulfated zwitterionic poly(sulfobetaine methacrylate) hydrogels promote complete skin regeneration.Acta Biomater.,2018,71, 293-305.
[14] Wang, Q.; Cai, H.; Hu, Z.; Wu, Y.; Guo, X.; Li, J.; Wang, H.; Liu, Y.; Liu, Y.; Xie, L.; Xu, K.; Xu, H.;He, H.*; Zhang, H.; Xiao, J.* Loureirin B promotes axon regeneration by inhibiting ER stress-induced mitochondrial dysfunction and regulating the Akt/GSK-3β pathway after spinal cord injury.J. Neurotraum.,2018, 5966.
[13] Wang, H.; Wu, Y.; Han, W.; Li, J.; Xu, K.; Li, Z.; Wang, Q.; Xu, K.; Liu, Y.; Xie, L.; Wu, J.; He, H.; Xu, H.; Xiao, J.* Hydrogen sulfide ameliorates blood-spinal cord barrier disruption and improves functional recovery by inhibiting endoplasmic reticulum stress-dependent autophagy. Front. Pharmacol.,2018,9, 1-16.
[12]He, H.; Markoutsa, E.; Li, J.; Xu, P.* Repurposing disulfiram for cancer therapy via targeted nanotechnology through enhanced tumor mass penetration and disassembly.Acta Biomater.,2018,68, 113-124.
[11]He, H.; Hashemi, L.; Hu, M.-L.*; Morsali, A.* The role of the counter-ion in metal-organic frameworks’ chemistry and applications.Coordin. Chem. Rev.,2018,376, 319-347.
[10] Chen, A.;He, H.*; Ma, G.; Li, Y.; Jiang, S.; Xuan, X.; Song, Y.; Zhang, C.; Xiao, J.; Xu, Y.; Wu, J.*; Chen, S. Biodegradable copolypeptide hydrogel prodrug accelerates dermal wound regeneration by enhanced angiogenesis and epithelialization.RSC Adv.,2018,8, 10620-10626.
[9] Wu, J.; He, C.;He, H.*; Cheng, C.; Zhu, J.; Xiao, Z.; Zhang, H.; Li, X.; Zheng, J.*; Xiao, J.* Importance of zwitterionic incorporation into polymethacrylate-based hydrogels for simultaneously improving optical transparency, oxygen permeability, and antifouling properties.J. Mater. Chem. B,2017,5, 4595-4606.


[8] Li, R.; Zou, S.; Wu, Y.; Li, Y.; Khor, S.; Mao, Y.; He, H.; Xu, K.; Zhang, H.; Li, X.; Wang, J.; Jiang, H.; Jin, Q.; Ye, Q.; Wang, Z.; Xiao, J.* Heparin-based coacervate of bFGF facilitates peripheral nerve regeneration by inhibiting endoplasmic reticulum stress following sciatic nerve injury.Oncotarget,2017, 1-13.


[7] He, Z.; Zou, S.; Yin, J.; Gao, Z.; Liu, Y.; Wu, Y.; He, H.; Zhou, Y.; Wang, Q.; Li, J.; Wu, F.; Xu, H. Z.; Jia, X.; Xiao, J.* Inhibition of Endoplasmic Reticulum Stress Preserves the Integrity of Blood-Spinal Cord Barrier in Diabetic Rats Subjected to Spinal Cord Injury.Sci. Rep.,2017,7, 1-14.
[6] He, Z.; Zhou, Y.; Huang, Y.; Wang, Q.; Zheng, B.; Zhang, H.; Li, J.; Liu, Y.; Wu, F.; Zhang, X.; Tong, S.; Wang, M.; Wang, Z.; He, H.; Xu, H.; Xiao, J.* Dl-3-n-butylphthalide improves functional recovery in rats with spinal cord injury by inhibiting endoplasmic reticulum stress-induced apoptosis.American Journal of Translational Research,2017,9, 1075-1087.
[5]He, H.; Markoutsa, E.; Zhan, Y.; Zhang, J.; Xu, P. Mussel-inspired PLGA/polydopamine core-shell nanoparticle for light induced cancer thermochemotherapy.Acta Biomater.,2017,59, 181-191.
[4]He, H.; Altomare, D.; Ozer, U.; Xu, H.; Creek, K.; Chen, H.; Xu, P.* Cancer cell-selective killing polymer/copper combination.Biomater. Sci.,2016,4, 115-120.
[3] Cheng, B.; He, H.; Huang, T.; Berr, S. S.; He, J.; Fan, D.; Zhang, J.; Xu, P.* Gold nanosphere gated mesoporous silica nanoparticle responsive to near-infrared light and redox potential as a theranostic platform for cancer therapy.Journal of Biomedical Nanotechnology,2016,12, 435-449.
[2]He, H.; Cattran, A. W.; Nguyen, T.; Nieminen, A. L.; Xu, P.* Triple-responsive expansile nanogel for tumor and mitochondria targeted photosensitizer delivery.Biomaterials,2014,35, 9546-9553.
[1] Cao, Z.; Chen, F.; Bao, N.; He, H.; Xu, P.; Jana, S.; Jung, S.; Lian, H.; Lu, C. Droplet sorting based on the number of encapsulated particles using a solenoid valve.Lab on a Chip,2013,13, 171-178.