孙运祥，男， 1986年5月出生，山东临沂人。2016年毕业复旦大学物理系，获博士学位。2016年-2019年美国Clemson大学物理与天文系从事博士后研究。2019年11月至今，宁波大学物理科学与技术学院副教授，硕士生导师。主要研究方向：利用分子动力学模拟方法研究蛋白质折叠、病理性聚集、功能性自组装以及纳米颗粒和有机药物分子等对蛋白质病理性聚集的调控机制。先后在Small、Nanoscale、Biomacromolecules、PCCP、JPCB、Nano Resarch等杂志先后发表论文30余篇。自2016应邀为JACS、ACS Chem Neurosci.、Langmuir、JPCB等国际知名杂志审稿。

联系方式：sunyunxiang@nbu.edu.cn
通讯地址：宁波市江北区风华路818号，宁波大学龙赛理科楼 315211

主持项目：
国家青年科学基金：淀粉样蛋白病理性聚集及αB-crystallin内源性蛋白对其调控机制的分子模拟研究，在研（22万）
宁波大学学术骨干启动经费，在研（50万）

代表论文：
Yunxiang Sun*, Feng Ding*, Thermo-and pH-responsive fibrillization of squid suckerin A1H1 peptide[J]. Nanoscale, 2020,12: 6307-6317
Yunxiang Sun, Aleksandr Kakinen, Yanting Xing, Pouya Faridi, Aparna Nandakumar, Anthony W. Purcell, Thomas P. Davis, Pu Chun Ke and Feng Ding. Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates[J]. Small, 2019: e**.
Yunxiang Sun, Aleksandr Kakinen, Chi Zhang, Ye Yang, Ava Faridi, Thomas P Davis, Weiguo Cao, Pu Chun Ke, Feng Ding. Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore[J]. Nanoscale, 2019, 11(24): 11933-11945.
Yunxiang Sun, Aleksandr Kakinen, Yanting Xing, Emily H Pilkington, Thomas P Davis, Pu Chun Ke, Feng Ding, Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide[J]. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 2019, 1865(2): 434-444.
Yunxiang Sun, Bo Wang, Xinwei Ge and Feng Ding, Distinct oligomerization and fibrillization dynamics of amyloid core sequences of amyloid-beta and islet amyloid polypeptide [J]. Phys. Chem. Chem. Phys., 2017, 19, 28414-28423 DOI: 10.1039/C7CP05695H. (impact factor: 3.906)
Yunxiang Sun, Zhenyu Qian and Guanghong Wei, The inhibitory mechanism of a fullerene derivative against amyloid-β peptide aggregation: an atomistic simulation study[J]. Phys. Chem. Chem. Phys., 2016, 18(18): 12582-12591
Yunxiang Sun, Zhenyu Qian, Cong Guo and Guanghong Wei, Amphiphilic peptides A₆K and V₆K display distinct oligomeric structures and self-assembly dynamics: a combined all-atom and coarse-grained simulation study[J]. Biomacromolecules, 2015, 16(9): 2940-2949.
Yunxiang Sun, Wenhui Xi, and Guanghong Wei, Atomic-level study of the effects of O4 molecules on the structural properties of protofibrillar Aβ trimer: β-sheet stabilization, salt bridge protection, and binding mechanism[J]. J. Phys. Chem. B, 2015, 119(7): 2786-2794
Aleksandr Kakinen#, Yunxiang Sun#, Ibrahim Javed, Ava Faridi, Emily H. Pilkington, Pouya Faridi, Anthony W. Purcell, Ruhong Zhou, Feng Ding, Sijie Lin, Pu Chun Ke, and Thomas P. Davis. Physical and Toxicological Profiles of Human IAPP Amyloids and Plaques[J]. Science Bulletin 2018. (共同一作)
Pu Chun Ke, Emily H Pilkington, Yunxiang Sun, Ibrahim Javed, Aleksandr Kakinen, Guotao Peng, Feng Ding, Thomas P Davis. Mitigation of Amyloidosis with Nanomaterials[J]. Advanced Materials, 2019: **.