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中国科学院昆明植物研究所导师教师师资介绍简介-胡江苗

本站小编 Free考研考试/2021-11-13

基本信息
胡江苗男硕导中国科学院昆明植物研究所
办公电话:
电子邮件: hujiangmiao@mail.kib.ac.cn
通信地址: 云南省昆明市黑龙潭蓝黑路132号
邮政编码: 650201

研究领域天然药物化学
聚焦兰科药用植物,阐明主成分并进行活性探索与功能产品开发

药物化学 天然活性成分发掘与利用
药物化学 天然产物结构修饰与活性评价

招生信息2021年招收硕士研究生1-2名


招生方向 药物化学
天然药物化学

药物化学 天然活性成分发现与功能

教育背景2002-09--2007-06中国科学院研究生院研究生学习/博士
1998-09--2002-06安徽中医学院本科学习/学士

学历 博士研究生

学位 博士

工作经历2007.7 – 2009.12, 中科院昆明植物所植化重点室助理研究员。
2010.1 – 今, 中科院昆明植物所植化重点室副研究员。
2013年,遴选为中科院昆明植物所硕士研究生导师,。
2015年,云南省中青年学术技术带头人后备人才。

工作简历 2010-01~现在,中国科学院昆明植物研究所,副研究员
2007-07~2009-12,中国科学院昆明植物研究所,助理研究员


专利与奖励
专利成果 ( 1 ) 紫果西番莲茎及叶提取物及其药物组合物与抗抑郁作用, 发明, 2013, 第 1 作者, 专利号: CN A
( 2 ) 一种铁皮石斛复方制剂及其制备方法, 发明, 2017, 第 1 作者, 专利号: CNA
( 3 ) 蜘蛛香环烯醚萜部位在制备N-型钙通道抑制剂中的应用, 发明, 2015, 第 1 作者, 专利号: 7.4
( 4 ) 一种山竹果壳中主要成分的制备方法及其在制药中的应用, 发明, 2017, 第 1 作者, 专利号: CNA
( 5 ) 白及属植物中militarine部位及单体的制备方法及其应用, 发明, 2017, 第 1 作者, 专利号: CNA
( 6 ) 美花石斛提取物及其在制备化妆品中的应用, 发明, 2018, 第 2 作者, 专利号: CNA
( 7 ) 生物素-鬼臼毒素酯化衍生物及其药物组合物和其制备方法与应用, 发明, 2014, 第 3 作者, 专利号: ZL20**
( 8 ) 鬼臼毒素糖苷物和酰化糖苷物及其药物组合物和其制备方法与应用, 发明, 2016, 第 3 作者, 专利号: ZL20**


出版信息
发表论文 (1)Structural characterization and hypoglycemic effect via stimulating glucagon-like peptide-1 secretion of two polysaccharides from Dendrobium officinale.,Carbohydrate Polymers,2020,通讯作者
(2)Three new compounds from the flower branch of Gastrodia elata Blume and anti-microbial activity,RSC Advances,2020,通讯作者
(3)Four new sesquiterpene derivatives from Dendrobium findlayanum,Chinese Journal of Natural Medicines,2019,通讯作者
(4)Phenolic Constituents with Antioxidative, Tyrosinase Inhibitory and Anti?aging Activities from Dendrobium loddigesii Rolfe,Natural Products and Bioprospecting,2019,通讯作者
(5)Total synthesis of dryocrassin ABBA and its analogues with potential inhibitory activity against drug-resistant neuraminidases,Bioorganic & Medicinal Chemistry,2019,通讯作者
(6)Glucoside Derivatives of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity,Drug Design, Development and Therapy,2019,通讯作者
(7)Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents,Frontier Chemistry,2019,通讯作者
(8)Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells,Natural Product Research,2019,通讯作者
(9)Synthesis and antitumor activity of camptothecin-4β-triazolopodophyllotoxin conjugates,Natural Product Research,2019,通讯作者
(10)13,27-Cycloursane, ursane and oleanane triterpenoids from the leaves of Lucuma nervosa,Fitoterapia,2019,通讯作者
(11)Stilbenes with anti-inflammatory and cytotoxic activity from the rhizomes of Bletilla ochracea Schltr,Fitoterapia,2018,通讯作者
(12)Structural elucidation and antioxidant activity of an arabinogalactan from the leaves of Moringa oleifera,International journal of biological macromolecules,2018,通讯作者
(13)Seco-Dendrobine-Type Alkaloids and Bioactive Phenolics from Dendrobium findlayanum,Journal of Natural Products,2018,通讯作者
(14)Design, synthesis and structure-activity relationships of mangostin analogs as cytotoxic agents,RSC Advance,2018,通讯作者
(15)Triterpenoids and iridoids from Patrinia scabiosaefolia,Fitoterapia,2017,通讯作者
(16)Ca v 2.2 and Ca v 3.1 calcium channel inhibitors from Valeriana jatamansi Jones,RSC Advances,2017,通讯作者
(17)Sesquiterpene amino ether and cytotoxic phenols from Dendrobium wardianum Warner,Fitoterapia,2017,通讯作者
(18)Polysaccharides of Dendrobium officinale Kimura & Migo protect gastric mucosal cell against oxidative damage-induced apoptosis in vitro and in vivo,Journal of Ethnopharmacology,2017,通讯作者
(19)Triterpenoids and iridoids from Patrinia scabiosaefolia,Fitoterapia,2017,通讯作者
(20)Iridoids and bis-iridoids from Patrinia scabiosaefolia,RSC advance,2017,通讯作者
(21)Four new glycosides from the stems of Dendrobium fimbriatum Hook,Natural Product Research,2017,通讯作者
(22)Structural characterization and immunomodulating activity of polysaccharide from Dendrobium officinale,International Journal of Biological Macromolecules,2016,通讯作者
(23)Oleanane-type triterpene saponins from Hydrocotyle nepalensis,Fitoterapia,2016,通讯作者
(24)Protective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell,Fitoterapia,2016,通讯作者
(25)Volvalerine A, an unprecedented N-containing sesquiterpenoid dimer derivative from Valeriana officinalis var. latifolia,Fitoterapia,2016,通讯作者
(26)Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells,Phytochemistry,2015,通讯作者
(27)全丁酰糖基化鬼臼毒素修饰物及其抗肿瘤活性,Synthesis and antitumor activity of novel per-butyrylated glycosides of podophyllotoxin and its derivatives,Bioorganic Medicinal Chemistry,2015,通讯作者
(28)蜘蛛香环烯醚萜与倍半萜, Iridoids and sesquiterpenoids from the roots of Valeriana jatamansi Jones,Fitoterapia,2015,通讯作者
(29)全丁酰糖基化4β三唑环鬼臼毒素的设计合成与肿瘤细胞毒活性评价,Design, synthesis, and cytotoxicity of per-butyrylated glycosides of 4β-triazole-podophyllotoxin derivatives,Molecules,2015,通讯作者
(30)流苏石斛中抗肿瘤活性联苄,Cytotoxic bibenzyl dimers from the stems of Dendrobium fimbriatum Hook,Bioorganic Medicinal Chemistry Letters,2014,通讯作者
(31)兜唇石斛中5个新酚类化合物, Five new phenolic compounds from Dendrobium aphyllum,Fitoterapia,2014,通讯作者
(32)铁皮石斛中两个新的具有神经营养作用的铁皮石斛素,Two New dendrocandins and neurite outgrowth-promoting activity from Dendrobium officinale,Journal of Asian Natural Products Research,2014,通讯作者
(33)Synthesis and Anticancer Activity of Glucosylated Podophyllotoxin Derivatives Linked via 4β-Triazole Rings,Molecules,2013,通讯作者
(34)Nardokanshone A, a new type of sesquieterpenoid–chalcone hybrid from Nardostachys chinensis,Tetrahedron Letters,2013,通讯作者
(35)Inhibitory activities on nitric oxide production of stilbenoids from Pholidota yunnanensis, Journal of Asian Natural Products Research,2013,通讯作者
(36)C-dideoxyhexosyl flavones from the stems and leaves of Passiflora edulis Sims,Food Chemistry,2013,通讯作者
(37)Dendrowardols A and B, Two New Sesquiterpenoids from Dendrobium wardianum Warner,Tetrahedron Letters,2013,通讯作者
(38)Dendrowardol C, a novel sesquiterpenoid from Dendrobium wardianum,Natural Products and Bioprospecting,2013,通讯作者
(39)Chemical components of Dendrobium crepidatum and their neurite outgrowth enhancing activities,Natural Products and Bioprospecting,2013,通讯作者
(40)Cycloartane Triterpenoid Saponins from water soluble of Passiflora edulis Sims and their antidepressant-like effects,Journal of Ethnopharmacology,2013,通讯作者


科研活动
科研项目 ( 1 ) 云南铁皮石斛深加工关键技术研究和产业化, 参与,省级,2013-12--2016-11
( 2 ) 石斛总酚的应用开发研究, 主持,研究所(学校),2013-12--2016-11
( 3 ) 生物素及糖苷化修饰鬼臼毒素类似物抗肿瘤药物研发, 主持,省级,2015-07--2018-06
( 4 ) 石斛抗衰老、美白及石斛花芳香物质研究, 主持,院级,2016-08--2019-08
( 5 ) 石斛的安全性和新功能的开发, 主持,院级,2018-01--2020-12
( 6 ) 铁皮石斛功能组分新功效研究与应用, 主持,省级,2017-01--2019-12
( 7 ) 云贵高原植物代谢物的分离及制备, 主持,国家级,2017-07--2020-12


指导学生已指导学生
池晓倩硕士研究生085235-制药工程
现指导学生
徐静悦硕士研究生105500-药学
缪宇硕士研究生105500-药学
杨晓蓓硕士研究生078001-药物化学
李金玉博士研究生100701-药物化学


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