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石河子大学动物科技学院导师教师师资介绍简介-(博士研究生导师、硕士研究生导师)张辉教授

本站小编 Free考研考试/2021-11-30



张辉,男,硕士生导师。兵团中青年科技创新领军人才兵团高等学校优秀青年教师兵团英才第二层次中国畜牧兽医学会动物传染病学流行病学专业组常委。现任石河子大学动物科技学院副院长。
一、教育经历:
2002年在山东农业大学本科毕业,2005年在新疆农业大学获得硕士学位;2009年在石河子大学获得博士学位。
二、导师资格
博士研究生导师、硕士研究生导师
三、主要研究内容
人兽共患病致病机制与防控;生物分子结构与功能、功能基因组学研究;新型检测技术和疫苗的产品研发。
四、近三年主持的主要科研项目
(1) 国际科技合作重点项目,新型布鲁氏菌病鉴别诊断技术的联合研发。
(2) 国家自然基金,布鲁氏菌感染宿主细胞过程中NF-κB调控细胞凋亡的分子机制。
(3) 国家自然基金,布鲁氏菌外膜蛋白OMP25对宿主细胞自噬/凋亡信号通路的调控机制研究。
(4) 国家重点研发计划子课题,布鲁氏菌毒力蛋白对宿主关键分子调控机制研究。
五、近发表论文(作为通讯作者)
(1) Deletion oftheType IV Secretion System Effector VceA Promotes Autophagy andInhibits Apoptosis inBrucella-Infected Human Trophoblast Cells. Current Microbiology, 2019, DOI 10.1007/s00284-019-01651-6.
(2) Expression and functional analysis of Brucella outer membrane protein 25 in recombinant goat pox virus. MOL MED REP, 2019, 19: 2323-2329.
(3) Brucella abortus phosphoglyceromutase and dihydrodipicolinate reductase induce Th1 and Th2-related immune responses. World J Microbiol Biotechnol, 2018, 34(22): 1-8.
(4) Development and evaluation of in murine model, of an improved livevaccine candidate against brucellosis from to Brucella melitensis vjbR deletion mutant. Microbial Pathogenesis, 2018, 124 (2018): 250-257.
(5) Outer Membrane Protein 25 of Brucella Activates Mitogen-Activated Protein Kinase Signal Pathway in Human Trophoblast Cells. Front. Vet. Sci. 2017, 4:197.
(6) Transcriptional regulator GntR of Brucella abortus regulates cytotoxicity, induces the secretion of inflammatory cytokines and affects expression of the type IV secretion system and quorum sensing system in macrophages. World J Microbiol Biotechnol, 2017, 33:60.
(7) Deletion of the transcriptional regulator GntR down regulated the expression of Genes Related to Virulence and Conferred Protection against Wild-Type Brucella Challenge in BALB/c Mice. 2017, Molecular Immunology, 92 (2017): 99-105.
(8) Brucella abortus 2308 DNodVDNodW double-mutant is highly attenuated and confers protection against wild-type challenge in BALB/c mice. Microb Pathogenesis, 2017, 106: 30-39.
(9) Construction and Characteristic Analysis of Omp10 Deletion Mutant of Brucella abortus. Pakistan J. Zool., 2017, 49(5): 1809-1816.
(10) Brucella melitensis M5-90△bp26 as a potential live vaccine that allows for the distinction between natural infection and immunization. Canadian journal of microbiology. 2017, 63(8): 719-729.
六、联系方式
电子邮箱:@qq.com;联系电话:





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