Assistant Professor of Molecular Biology

Contact

aj.te.velthuis@princeton.edu
609-258-2053
Thomas Laboratory, 103

Faculty Assistant

Mary Gidaro

Education

Ph.D. Medicine (Molecular Virology) Leiden University, Leiden, The Netherlands
B.Sc. Biology Leiden University, Leiden, The Netherlands

Research Area

Microbiology & Virology

Research Focus

Innate immune responses and replication of RNA viruses

Website

te Velthuis lab website




Research
Selected Publications
Innate immune responses and replication of RNA viruses




Bisht K, Velthuis AJWTe. Decoding the Role of Temperature in RNA Virus Infections. mBio. 2022 ;:e0202122. PubMed
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French H, Pitre E, Oade MS, Elshina E, Bisht K, King A, et al. Transient RNA structures cause aberrant influenza virus replication and innate immune activation. Sci Adv. 2022 ;8(36):eabp8655. PubMed
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Pitre E, Velthuis AJWTe. Tinker, tailor, antiviral: RNA virus inhibition by induced recombination. Trends Biochem Sci. 2022 ;47(6):456-458. PubMed
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Nilsson-Payant BE, tenOever BR, Velthuis AJWTe. The Host Factor ANP32A Is Required for Influenza A Virus vRNA and cRNA Synthesis. J Virol. 2022 ;96(4):e0209221. PubMed
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Elli S, Bojkova D, Bechtel M, Vial T, Boltz D, Muzzio M, et al. Enisamium Inhibits SARS-CoV-2 RNA Synthesis. Biomedicines. 2021 ;9(9). PubMed
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Elshina E, Velthuis AJWTe. The influenza virus RNA polymerase as an innate immune agonist and antagonist. Cell Mol Life Sci. 2021 ;78(23):7237-7256. PubMed
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Alnaji FG, Reiser WK, Rivera-Cardona J, Velthuis AJWTe, Brooke CB. Influenza A Virus Defective Viral Genomes Are Inefficiently Packaged into Virions Relative to Wild-Type Genomic RNAs. mBio. 2021 ;12(6):e0295921. PubMed
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Velthuis AJWTe, Grimes JM, Fodor E. Structural insights into RNA polymerases of negative-sense RNA viruses. Nat Rev Microbiol. 2021 ;19(5):303-318. PubMed
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Pitre E, Velthuis AJWTe. Understanding viral replication and transcription using single-molecule techniques. Enzymes. 2021 ;49:83-113. PubMed
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Fodor E, Velthuis AJWTe. Structure and Function of the Influenza Virus Transcription and Replication Machinery. Cold Spring Harb Perspect Med. 2020 ;10(9). PubMed
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