Title/Position
Assistant Professor

Degree
Ph.D., Princeton University, 2014

pritykin(@cs.princeton.edu) (609) 258-4522 245 Carl Icahn Lab

Homepage
https://www.cs.princeton.edu/~pritykin

Other Affiliations
Genomics

Research

Interests: Computational biology, functional genomics, single-cell technologies, regulation of gene expression, immunology, cancer
Research Areas: Computational Biology

Short Bio

Yuri Pritykin is an assistant professor of computer scienceand the Lewis-Sigler Institute for Integrative Genomics. He received his PhD in computer science from Princeton University and MSc and PhD in mathematics from Lomonosov Moscow State University. His main interest and expertise arein using applied statistics, machine learning, and efficientalgorithms to address fundamental problems in biology and medicineby integrative analysis of multi-dimensional data. He was awarded AACR-Bristol-Myers Squibb Immuno-oncology Research Fellowship (2019) and Memorial Sloan Kettering-Parker Institute for Cancer Immunotherapy-Cycle for SurvivalFund (2018).

Selected Publications

Yuri Pritykin*, Joris van der Veeken*, Allison Pine, Yi Zhong, Merve Sahin, Linas Mazutis, Dana Pe’er, Alexander Rudensky, Christina Leslie (2020). A unified atlas of CD8 T cell dysfunctional states in cancer and infection. Molecular Cellhttps://doi.org/10.1016/j.molcel.2021.03.045
Xiaoyi Li*, Yuri Pritykin*, Carla P Concepcion*, Yuheng Lu, Gaspare La Rocca, Minsi Zhang, Bryan King, Peter J Cook, Yu Wah Au, Olesja Popow, Joao A.Paulo, Hannah G Otis, Chiara Mastroleo, Paul Ogrodowski, Ryan Schreiner, Kevin M Haigis, Doron Betel, Christina S Leslie, Andrea Ventura (2020). High-Resolution in vivo identification of miRNA targets by Halo-enhanced Ago2 pull-down. Molecular Cell https://doi.org/10.1016/j.molcel.2020.05.009
Chrysothemis C Brown, Herman Gudjonson, Yuri Pritykin, Deeksha Deep, Vincent-Philippe Lavallée, Alejandra Mendoza, Rachel Fromme, Linas Mazutis, Charlotte Ariyan, Christina Leslie, Dana Pe’er, Alexander Y Rudensky (2019). Transcriptional basis of mouse and human dendritic cell heterogeneity. Cell https://doi.org/10.1016/j.cell.2019.09.035
Catherine Konopacki*, Yuri Pritykin*, Yury Rubtsov, Christina S. Leslie, Alexander Y. Rudensky (2019). Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function. Nature Immunology https://doi.org/10.1038/s41590-018-0291-z
Alexendar R Perez*, Yuri Pritykin*, Joana A Vidigal*, Sagar Chhangawala, Lee Zamparo, Christina S Leslie, Andrea Ventura (2017). GuideScan software for improved single and paired CRISPR guide RNA design. Nature Biotechnology https://doi.org/10.1038/nbt.3804
?* equal contribution