Danielle S Ahn, MD

Specialties:
Pediatrics, Pediatric Critical Care Medicine

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Treats Children

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Overview
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Credentials & Experience
Research

Overview

Dr. Ahn's clinical work is in the pediatric intensive care unit, where many of the sickest children in the hospital are suffering the consequences of respiratory failure. Care for these children has changed very little over the past few decades and is limited to supportive care such as antibiotics, ventilator support and nutrition. Her experience caring for these children has compelled Dr. Ahn to investigate the mechanisms that underly the severe respiratory disease that we see in children and the sometimes abnormal and devastating response to rather common pathogens.
To accomplish this goal, Dr. Ahn has devoted her research time to the study of innate immune cell recruitment and related signaling pathways in response to multi-drug resistant bacteria in pulmonary infections. Under the mentorship of Dr. Alice Prince, Dr. Ahn has utilized in vivo and in vitro models of infection and immunologic and molecular biology techiniques to ask hypothesis-driven questions. This is all in an effort to identify potential therapeutic targets to help the immune system overcome these bacteria that have gained antimicrobial resistance. This effort is very important with increasing morbidity and mortality in the immunocompromised and critically ill.

Areas of Expertise / Conditions Treated

Pediatric Critical Care Specialist

Academic Appointments

Assistant Professor of Pediatrics

Hospital Affiliations

NewYork-Presbyterian / Columbia University Irving Medical Center

Languages

Spanish

Gender

Female

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Insurance Accepted

Aetna

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HMO
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POS
PPO
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Local 1199

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MagnaCare

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Multiplan

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UnitedHealthcare

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Credentials & Experience

Education & Training

MD, University of Virginia School of Medicine
Residency: Bellevue Hospital Center
Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center

Board Certifications

Pediatrics
Pediatric Critical Care Medicine

Research

Dr. Ahn has devoted herresearch time to the study of innate immune cell recruitment and related signaling pathways in response to multi-drug resistant bacteria in pulmonary infections. Identifying therapies to improve the host immune system response to illness due to bacterial infections has become even more important with the rise of antibiotic resistance and high morbidity and mortality in our immunocompromised and critically ill patients. To understand the molecular biology and immunology of these pulmonary infections, Dr. Ahn has utilized animal and in vitro cell culture models, cytokine analysis, multi-color flow cytometry, immunohistochemical staining, and imaging by confocal microscopy. She has expanded the skills she developed under the guidance of Dr. Alice Prince, from her original studies in T-cell and macrophage biology in response to MRSA to the role of resident and recruited macrophages and monocytes in response to another multi-drug resistant pathogen, Klebsiella pneumoniae.


For a complete list of publications, please visit PubMed.gov