Monica Bhatia, MD
Specialties:
Cancer Care, Pediatric Hematology-Oncology, Pediatrics
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Treats Children
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Overview
Monica Bhatia, MD specializes in the care of children with noncancerous blood disorders who may benefit from bone marrow transplantation, especially sickle cell anemia. She and her colleagues are working to reduce the toxicity (side effects) and complications of this treatment without compromising its effectiveness, and to make it available to more patients.The field of pediatric hematology brings with it many intellectual challenges, and bone marrow transplantation in particular is especially dynamic. Dr. Bhatia has the opportunity to provide care for the sickest children, potentially curing their disease. She builds strong relationships with her patients and their families that last for years. It is inspiring for her to see young patients grow up to lead healthy, productive lives.
NewYork-Presbyterian/Morgan Stanley Children's Hospital has a robust program for bone marrow transplantation for sickle cell anemia - the only cure for this disease. Dr. Bhatia and her team have witnessed remarkable results among children who are cured with bone marrow transplantation and spared from the potentially life-threatening complications of sickle cell disease.
Yet despite the advances made, only 15 percent of patients with sickle cell disease have a matched sibling bone marrow donor. Therefore, Dr. Bhatia and her team conduct research to evaluate a procedure called "CD34-selected stem cell transplantation" to remove T-cells from donor bone marrow for patients without a matched sibling donor. This approach reduces the risk of graft-versus-host disease (GVHD), a potential complication of bone marrow transplantation in which T-cells from the donor attack the tissue of the recipient. This approach to harnessing stem cells could potentially make bone marrow transplantation a safer, effective option for many patients who are seeking a cure for sickle cell disease.
Dr. Bhatia and her colleagues are currently assessing reduced-intensity transplantation, which uses lower doses of chemotherapy to decrease the risk of side effects and long-term complications without lowering the effectiveness of treatment. She is also interested in looking for ways to further improve the quality of life of patients who have had a bone marrow transplant in addition to fertility preservation.
Areas of Expertise / Conditions Treated
Acute Myeloid LeukemiaBone Marrow Disorders
Bone Marrow Stem Cell Transplants
Chemotherapy
Hemoglobinopathy
Immunodeficiency Disorder
Pediatric Bone Marrow
Sickle Cell Anemia
Academic Appointments
Associate Professor of Pediatrics at CUMCAdministrative Titles
Director, Pediatric Stem Cell Transplant ProgramHospital Affiliations
NewYork-Presbyterian / Columbia University Irving Medical CenterNewYork-Presbyterian Morgan Stanley Children's Hospital
Gender
FemaleSchedule an Appointment
Phone Appointments
New and Existing Patients: (212) 305-9770
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Location(s)
CUIMC/NewYork-Presbyterian Morgan Stanley Children's Hospital3959 Broadway
CHN 10-07
New York, NY 10032
Primary
Phone: (212) 305-9770
Fax: (212) 305-8408
Open location in Google Maps
CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
New York, NY 10032
Phone: (212) 305-9770
Fax: (212) 305-8408
Open location in Google Maps
Insurance Accepted
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Credentials & Experience
Education & Training
St. George's University School of Medicine (Grenada)Residency: Albany Medical Center Hospital, NY
Fellowship: Childrens National Medical Center
Board Certifications
PediatricsPediatric Hematology-Oncology
NY Top Doctor
Research
Clinical Trials
NCT00408447 Allogeneic Stem Cell Transplant to Induce Mixed Donor Chimerism in Patients With Sickle Cell Disease and ThalassemiaNCT00920972 A Study of Hematopoietic Stem Cell Transplantation (HSCT) in Non-Malignant Disease Using a Reduced-Intensity Preparatory Regime
NCT02452034 A Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous (IV) and Powder for Oral Suspension Formulations of Posaconazole (POS) in Immunocompromised Pediatric Subjects With Neutropenia
NCT02766465 A Study to Compare Bone Marrow Transplantation to Standard Care in Adolescents and Young Adults With Severe Sickle Cell Disease (BMT CTN #1503)
NCT02851407 A Phase 3, Randomized, Adaptive Study Comparing the Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients Undergoing Hematopoietic Stem Cell Transplant
NCT02867800 Abatacept for Graft Versus Host Disease Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease: a Sickle Transplant Alliance for Research Trial
For a complete list of publications, please visit PubMed.gov
Related News
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October 5, 2020