哥伦比亚大学儿科学系导师教师师资介绍简介-Richard Joseph Deckelbaum, MD

本站小编 Free考研考试/2022-10-06

Richard Joseph Deckelbaum, MD


Specialties:
Gastroenterology, Pediatric Gastroenterology, Pediatrics

More specialties
Treats Children










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Overview
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Location(s)
Credentials & Experience
Research


Overview

richard_j._deckelbaum_md_-_robert_r._williams_professor_of_nutrition





Areas of Expertise / Conditions Treated

Nutrition



Academic Appointments

Professor of Epidemiology
Robert R. Williams Professor of Nutrition (in Pediatrics)



Hospital Affiliations

NewYork-Presbyterian / Columbia University Irving Medical Center
NewYork-Presbyterian Morgan Stanley Children's Hospital



Languages

French
Hebrew



Gender

Male





Schedule an Appointment

Phone Appointments



New and Existing Patients: (212) 305-5903




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Location(s)

CUIMC/Presbyterian Hospital and Vanderbilt Clinic
622 West 168th Street
Suite 1512
New York, NY 10032

Primary

Phone: (212) 305-5903



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Credentials & Experience

Education & Training

McGill University Faculty of Medicine
Residency: Montreal Children's Hospital
Residency: Hadassah University Medical Center, Israel
Fellowship: Boston University
Fellowship: Massachusetts Institute of Technology



Board Certifications

Pediatrics





Research

The major focus of Dr. Deckelbaum’s laboratory is to determine regulatory mechanisms for cell-lipid particle interaction, and cell cholesterol and triglyceride metabolism. Current projects are defining the effects of lipid particle properties on their metabolism in the whole animal, and in cells, via receptor-mediated and receptor-independent pathways. Integrated with these studies are studies on how different lipids, omega-3 and other free fatty acids regulate gene expression and focus on genes and mechanisms affecting atherogenesis, myocardial infarction and stroke. Dr. Deckebaum’s initial research training as a postdoctoral fellow in biophysics using NMR, calorimetry, and X-ray techniques to study the structure of lipoproteins has allowed him throughout his career to understand the importance of physical structure of different lipids in the biochemistry and in the molecular biology of lipids and lipid metabolism. Having been funded continuously for over thirty years by NIH R01s and PPGs focusing on triglyceride emulsions, lipoprotein metabolism, and lipid metabolism in in vitro and in vivo, we have obtained very exciting results over the years showing that EPA/DHA rich diets have the ability to inhibit pathways associated with atherogenesis in four different rodent models. Our laboratory has shown that acute administration of omega-3 fatty acids also provides major neuro- and cardioprotection after stroke and myocardial infarction in rodent models. Of the pre- and postdoctoral trainees Dr. Deckelbaum has mentored over the past 30 years, over 45 now have full-time academic positions at universities or are heading nutrition-related roles in industry and government.


Grants

NIH R21 NS109717, RJ Deckelbaum (PI) 08/15/2019-07/31/2021 "n-3 Diglyceride Emulsions: Characterization of a Novel Neuroprotectant"
NIH RO1 NS088197, RJ Deckelbaum (PI) 04/01/15-03/31/20 “Omega-3 Fatty Acids: Acute Neuroprotection via Mitochondria”
NIH 2P30 DK63068-06, D Accili (PI); RJ Deckelbaum (Mentor) 02/01/08-01/31/23 “Diabetes and Endocrinology Center”
NIH T32 DK07647-26, RJ Deckelbaum (Co-PI) 09/01/95-08/31/20 “Graduate Training in Nutrition”
NIH R01 HL141823, A Moran (PI); RJ Deckelbaum (Co-PI) 09/01/18-08/31/23 “Familial hypercholesterolemia screening in children: population impact of phenotype, genotype and cascade approaches”
Private, RJ Deckelbaum (PI) 06/01/16-12/31/19
“Characterization and Effects of an MCT-Fish Oil Intravenous Lipid Emulsion in Rodent Models”



For a complete list of publications, please visit PubMed.gov