Margaret T. Lee, MD
Specialties:
Cancer Care, Pediatric Hematology-Oncology, Pediatrics
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Treats Children
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Research
Overview
Margaret T. Lee, MD cares for children with blood disorders, such as anemias (sickle cell anemia, thalassemia, and iron deficiency), bleeding (including idiopathic thrombocytopenic purpura [ITP], hemophilia, and von Willebrand disease), and clotting disorders (such as deep vein thrombosis).Dr. Lee's main research focus is sickle cell disease. She is seeking new ways to prevent the complications of sickle cell disease, particularly those affecting the brain and lungs. Currently, she is investigating whether high-dose vitamin D therapy can reduce respiratory complications in children with sickle cell disease. In addition to its well-known role in maintaining healthy bones, vitamin D has been shown to have anti-infective and anti-inflammatory effects that may benefit patients with sickle cell disease. Dr. Lee is also the site investigator for the National Institutes of Health-funded series of multicenter clinical trials on stroke prevention in children with sickle cell anemia (STOP 1 and 2, SWiTCH, and TWiTCH).
Dr. Lee's other area of interest is a rare group of diseases called vascular anomalies. There is relatively little known about these disorders, and the care of patients with vascular anomalies requires a multidisciplinary group of physicians from several specialties (dermatology, surgery, cardiology, neurology, and hematology/oncology)-all of whom are available at NewYork-Presbyterian/Morgan Stanley Children's Hospital. Hematologists play a role in the medical treatment of vascular tumors and the supportive care of clotting and bleeding complications that are associated with some types of vascular malformations. Dr. Lee is an active participant in the Vascular Anomalies Group at NYP/Morgan Stanley Children's Hospital, as well as the Vascular Anomalies Special Interest Group of the American Society of Pediatric Hematology/Oncology, which is looking at novel therapies for vascular anomalies and their complications.
Areas of Expertise / Conditions Treated
Arteriovenous Malformation (AVM)Bannayan-Riley-Ruvalcaba syndrome (BRRS)
Bleeding Disorder
Blue Rubber Bleb Nevus Syndrome
Hemangioma
Hemostasis
Hereditary Hemorrhagic Telangiectasia (HHT)
Kaposiform Hemangioendothelioma
Klippel Trenaunay Syndrome
Lymphangioma
Lymphatic Malformation
Lymphedema
Parkes-Weber syndrome
PIK3-related Overgrowth Spectrum (PROS, CLOVES, MC
Proteus Syndrome
PTEN-related overgrowth syndrome
Sickle Cell Anemia
Thrombosis
Tufted Angioma
Vascular Anomaly
Vascular Birthmark
Vascular Malformation
Vascular Tumor
Academic Appointments
Associate Professor of Pediatrics at CUMCHospital Affiliations
NewYork-Presbyterian / Columbia University Irving Medical CenterNewYork-Presbyterian Morgan Stanley Children's Hospital
Gender
FemaleSchedule an Appointment
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Phone Appointments
New and Existing Patients: (212) 305-6290
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Location(s)
ColumbiaDoctors - 15 North Broadway15 North Broadway
White Plains, NY 10601
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CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
New York, NY 10032
Phone: (212) 305-9770
Fax: (212) 305-5420
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Insurance Accepted
Aetna
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Credentials & Experience
Education & Training
University of Santo Tomas (Philippines)Residency: New York University Medical Center
Fellowship: New York University Medical Center
Board Certifications
Pediatric Hematology-OncologyResearch
Clinical Trials
NCT02187003 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study To Evaluate The Efficacy And Safety Of Rivipansel (Gmi-1070) In The Treatment Of Vaso-occlusive Crisis In Hospitalized Subjects With Sickle Cell DiseaseNCT02433158 An Open-label Extension Study To Evaluate The Safety Of Rivipansel (Gmi-1070) In The Treatment Of One Or More Vaso-occlusive Crises In Hospitalized Subjects With Sickle Cell Disease
COMPLETED
NCT01276587 Pilot Study of Vitamin D Therapy to Prevent Respiratory Complications in Children With Sickle Cell Disease
For a complete list of publications, please visit PubMed.gov