Rudolph L. Leibel, MD

Specialties:
Pediatrics

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Overview
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Location(s)
Credentials & Experience
Research

Overview

Dr. Leibel's research focuses on the genetics of obesity and noninsulin-dependent diabetes. His laboratory has mapped, cloned, and identified mutations in the obese and fatty genes in rats, mice, and, more recently, in humans. The obese gene encodes leptin, an adipose derived hormone responsible for regulating body weight, whereas the fatty gene encodes the leptin receptor. Currently, his research group is defining the physiological bases by which this and related signaling networks regulate body size and composition. For example, changes in leptin production following reduction in body fat might play a role in the metabolic changes that accompany weight loss in humans. Dr. Leibel's laboratory is also working to isolate additional rodent genes that influence body weight and the susceptibility to noninsulin dependent diabetes mellitus in the context of obesity. Laboratory members have extended their genetic studies to search for similar obesity and diabetes related genes in human families.

Areas of Expertise / Conditions Treated

Obesity

Academic Appointments

Professor of Pediatrics
Professor of Medicine

Administrative Titles

Co-Director, Naomi Berrie Diabetes Center
Chief, Division of Pediatric Molecular Genetics

Hospital Affiliations

NewYork-Presbyterian Morgan Stanley Children's Hospital
NewYork-Presbyterian / Columbia University Irving Medical Center

Gender

Male

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Location(s)

CUIMC/Russ Berrie Medical Science Pavilion
1150 St. Nicholas Avenue
Floor 6
New York, NY 10032



Phone: (212) 851-5257



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Credentials & Experience

Education & Training

Albert Einstein College of Medicine - Yeshiva University
Internship: Massachusetts General Hospital
Residency: Massachusetts General Hospital
Residency: Children's Hospital of Boston
Fellowship: Massachusetts General Hospital

Board Certifications

Pediatrics

Research

Research Interests

Genetics of obesity and noninsulin-dependent diabetes



For a complete list of publications, please visit PubMed.gov