Andreas H. Kottmann, PhD
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OverviewResearch Overview
Email:
ak139@cumc.columbia.edu Academic Appointments
Adjunct Assistant Professor of Pathology and Cell Biology
Research
We study the regulation of competitive processes that lead to the structural and functional stability of the central nervous system and at the same time allow structural and functional plasticity necessary for learning and memory. We focus our research on the mesencephalic dopaminergic system and the spinal motor neuron system. Our work is of relevance to two prominent, progressive neurodegenerative disorders, Parkinson’s Disease and Amyotrophic Lateral Sclerosis.
Research Interests
The mesencephalic dopaminergic system and the spinal motor neuron system
Selected Publications
Gonzalez-Reyes LE, Verbitsky M, Blesa J, Jackson-Lewis V, Paredes D, Tillack K, Phani S, Kramer ER, Przedborski S, Kottmann AH. Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit. Neuron. 2012 Jul 26;75(2):306-19.