Russell Nicholls, PhD
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OverviewCredentials & Experience
Research
Overview
Email: rn95@cumc.columbia.eduAcademic Appointments
Assistant Professor of Pathology & Cell BiologyCredentials & Experience
Education & Training
BS, Cornell University - IthacaPhD, Harvard University
Research
Selected Publications
Hue C.D., Cho F.S., Cao S., Nicholls R.E., Vogel E.W., Sibindi C., Arancio O., Bass C.R., Meaney D.F., and Morrison B., (2015) Time Course and Size of Blood-Brain Barrier Opening in a Mouse Model of Blast-Induced Traumatic Brain Injury. Neurotrauma (in press)Teich A.F., Nicholls R.E., Puzzo D., Fiorito J., Purgatorio R., Fa M., Arancio O. (2015) Synaptic Therapy in Alzheimer's Disease: A CREB-centric Approach. Neurotherapeutics12:29-41.
Thualt S.J., Malleret G., Constantinople C.M., Nicholls R.E., Chen I., Zhu J., Panteleyev A., Vronskaya S., Nolan M.F., Bruno R., Seigelbaum S.A., Kandel E.R. (2013) Prefrontal Cortex HCN1 Channels Enable Intrinsic Persistent Neural Firing and Executive Memory Function. J Neurosci 33:13583-99.
Nicholls R.E., Alarcon J.M., Malleret G., Carroll R.C., Grody M., Vronskaya S., and Kandel E.R. (2008) Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility. Neuron 58: 104-17.
Bailey C.P., Nicholls R.E., Zhang X-L., Muller W., Kandel E.R., and Stanton P.K. (2008) Gαi2 inhibition of adenylate cyclase regulates presynaptic activity and unmasks cGMP-dependent long-term depression at Schaffer collateral-CA1 hippocampal synapses. Learning and Memory 15: 261-270.
Nicholls R.E., Zhang X-L., Bailey, C.P., Conklin B.R., Kandel E.R., and Stanton P.K. (2006) mGluR2 acts through inhibitory Gα subunits to regulate transmission and long-term plasticity at hippocampal mossy fiber-CA3 synapses. Proc. Nat. Acad. Sci. USA 103: 6380-6385.