Susan E. Bates, MD

Specialties:
Hematology, Internal Medicine, Medical Oncology

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Credentials & Experience

Overview

Dr. Susan Bates received her M.D. degree from the University of Arkansas School of Medicine. She completed her clinical training in internal medicine at Georgetown University in Washington, D.C., and in medical oncology at the National Cancer Institute (NCI) in Bethesda, MD. Dr. Bates was a Lead Clinical Investigator and Head of the Molecular Therapeutics Section in the Developmental Therapeutics Branch of the Center for Cancer Research before moving to Columbia University in August 2015.
During her years at the NCI, Dr. Bates led a highly successful translational research program focused on mechanisms of multidrug resistance and approaches to evaluate and improve the activity of epigenetic modifying agents. Her laboratory was among the first to clone the multidrug transporter ABCG2, eventually characterizing its function and its role in chemo-resistance and chemo-protection. This effort built upon earlier work elaborating the role of the multi-drug transporter P-glycoprotein that had defined the drug sensitivity profiles of cell lines in vitro, particularly in the NCI-60 cell line panel. The latter observation continues to impact how the NCI-60 cell line panel is used in drug discovery, and helped her identify a novel agent, at that time known as depsipeptide. Dr. Bates brought this drug to the clinic and after completing its phase I testing, served as Principal Investigator of a multi-institutional, international Phase II study of romidepsin (depsipeptide) in cutaneous and peripheral T-cell lymphoma. Working with Gloucester Pharmaceuticals, the data from this study were included in New Drug Applications (NDA) to the U.S. Food & Drug Administration (FDA). This partnership led to approval by the FDA of romidepsin for two indications - initially for cutaneous T-cell lymphoma and later for peripheral T-cell lymphoma.
Dr. Bates' current interests are both laboratory and clinical in nature. Her laboratory efforts include laboratory and translational studies on drug resistance in T-cell lymphomas and advanced solid tumors including breast, pancreatic, neuroendocrine, renal and lung cancers. Her work is dedicated to new drug development, and finding antineoplastic agents that, alone or in combination with other anticancer agents, improve the options available for difficult to treat cancers. Emanating from the clinical and translational development of romidepsin, a histone deacetylase (HDAC) inhibitor, a current focus is on epigenetic therapies, and the development of combination therapies to use with HDAC inhibitors in refractory advanced cancers, including solid tumors. She also has a special interest in drug delivery and drug distribution and the role of the blood brain barrier in creating a sanctuary site for cancers that metastasize to the brain. Clinically, her goal has always been to translate ideas from the laboratory to clinical trials, an effort that has proven very successful. Clinically she seeks to develop combination therapies with histone deacetylase inhibitors for the therapy of solid tumors; and to develop therapies to treat central nervous system metastases, a complication of cancer that is becoming a greater problem as patients live longer with cancer.

Areas of Expertise / Conditions Treated

Brain Metastases
Chemotherapy
Gallbladder Cancer
Liver Cancer
Oncology
Pancreatic Cancer
T-Cell Lymphoma

Academic Appointments

Professor of Medicine at CUMC

Administrative Titles

Director, Translational Cancer Medicine

Hospital Affiliations

NewYork-Presbyterian / Columbia University Irving Medical Center

Gender

Female

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Virtual Visits/Telehealth

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Phone Appointments

New and Existing Patients: (212) 305-5098

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Location(s)

CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
Floor 9
New York, NY 10032

Primary

Phone: (212) 305-5098


Fax: (212) 305-6891



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Insurance Accepted

Aetna

Aetna Signature Administrators
EPO
HMO
Medicare Managed Care
NYP Employee Plan
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POS
PPO
Student Health

Affinity Health Plan

Essential Plan
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AgeWell

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Amida Care

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Cigna

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Great West (National)
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Emblem/GHI

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Emblem/HIP

ConnectiCare
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POS
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Select Care (Exchange)
Vytra

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EPO
HMO
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Empire Blue Cross Blue Shield HealthPlus

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Healthfirst

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Local 1199

Local 1199

MagnaCare (National)

MagnaCare

Multiplan

Multiplan

MVP Health Care

Child/Family Health Plus
Essential Plan
HMO
Medicaid Managed Care

Oxford Health Plans

Freedom
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RiverSpring

Special Needs

UnitedHealthcare

Compass (Exchange)
Empire Plan
HMO
Medicaid (Community Plan)
Medicare Managed Care
POS
PPO

VNSNY CHOICE

Medicare Managed Care
SelectHealth
Special Needs

WellCare

Medicaid Managed Care
Medicare Managed Care

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

MD, 1978 University of Arkansas for Medical Sciences
Residency: 1980 University of Arkansas Medical Center
Residency: 1981 Georgetown University Medical Center
Fellowship: National Cancer Institute

Board Certifications

Internal Medicine
Medical Oncology