赵瑾 副教授
Email: zhaojin@tju.edu.cn
研究所：先进高分子材料研究所
个人简历
教育背景：
· 1996-2000，天津大学，材料学院，工学学士
· 2000-2003，天津大学，材料学院，工学硕士
· 2003-2006，天津大学，材料学院，工学博士
工作经历：
· 2006-至今，天津大学，材料学院高分子系，讲师，副教授
研究方向
· 研究领域：
可注射水凝胶，生物粘合材料，miRNA活化凝胶牙科材料，骨组织工程材料
· 讲授课程：
材料现代研究方法-高分子部分（本科）
高分子基工程复合材料（本科）
生物医用高分子材料-部分（研究生）
承担项目
1.“可注射microRNA活化水凝胶对炎症期巨噬细胞及干细胞的时序一体化调控及促骨修复研究”，国家基金面上项目，负责人，2017～2020。
2.“可注射microRNA活化凝胶掺杂骨粉促进植牙牙槽骨愈合的研究”，天津市面上项目，负责人，2017～2020。
3.“中药血清基组织粘附性可注射水凝胶的构建及其体内修复软骨研究”，国家基金合作项目，合作单位负责人，2016～2019。
4.“药物辅料产品性能检测及评价”，校企合作项目，负责人，2018～2019。
5.“多肽为交联剂的多糖-多肽原位凝胶及其用于周围神经吻合的应用基础研究”，国家基金青年基金项目，负责人，2012～2014。
6.“骨修复材料”，天津市项目，2007～2009。
7.“有机高聚物减水剂合成的技术指导”，校企合作项目，负责人，2011～2012。
标志性成果
l 发表文章、专著（代表作）：
1. Sidi Li, Ning Chen, Xueping Li, Yang Li, Zhipeng Xie, Zhenyu Ma,Jin Zhao*, Xin Hou, Xubo Yuan. Bioinspired Double-Dynamic-Bond Crosslinked Bioadhesive Enables Post-Wound Closure Care.Advanced Functional Materials, 2020: **.IF=15.621, top期刊
2. Qi Zhan, Kaikai Yi, Hongzhao Qi, Sidi Li, Xueping Li, Qixue Wang, Yunfei Wang, Chaoyong Liu, Mingzhe Qiu, Xubo Yuan,Jin Zhao*, Xin Hou*, Chunsheng Kang*, Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy. Theranostics,2020, doi:10.7150/thno.45028. IF=8.063, top期刊
3.Sidi Li, Luyang Chen, Kai Huang, Ning Chen, Qi Zhan, Kaikai Yi, Hongzhao Qi, Chaoyong Liu, Yanli Tan, Xin Hou, Yunfeng Lu,Jin Zhao*, Xubo Yuan*, Chunsheng Kang*. Tumor Microenvironment-Tailored Weakly Cell-Interacted Extracellular Delivery Platform Enables Precise Antibody Release and Function. Advanced Functional Materials,2019: **.IF=15.621, top期刊
4.Xiaomin Qian, Zhendong Shi, Hongzhao Qi, Ming Zhao, Kai Huang, Donglin Han, Junhu Zhou, Chaoyong Liu, Yang Liu, Yunfeng Lu, Xubo Yuan,Jin Zhao*, Chunsheng Kang*.A Novel Granzyme B Nanoparticle Delivery System Simulates Immune Cell Functions for Suppression of Solid Tumors.Theranostics, 2019, 9(25):7616-7627.IF=8.063, top期刊
5．Hongzhao Qi, Lijun Yang, Xueping Li, Qi Zhan, Donglin Han,Jin Zhao*, Xin Hou*, Xubo Yuan*. Exosomes Separated Based on the “STOP” Criteria for Tumor-Targeted Drug Delivery. Journal of Materials Chemistry B,2018, 6(18): 2758-2768.IF=5.047
6. Yalin Zhou,Jin Zhao*, Xiaolei Sun, Sidi Li, Xin Hou, Xubo Yuan, Xiaoyan Yuan, Rapid Gelling Chitosan/Polylysine Hydrogel With Enhanced Bulk Cohesive and Interfacial Adhesive Force: Mimicking Features of Epineurial Matrix For Peripheral Nerve Anastomosis, Biomacromolecules,2016, 17 (2): 622-630.IF=5.667, top期刊
7. Wei Nie, Xiaoyan Yuan,Jin Zhao*, Yalin Zhou, Huijing Bao, Rapidly in Situ Forming Chitosan/Epsilon-Polylysine Hydrogels for Adhesive Sealants and Hemostatic Materials, Carbohydrate Polymers, 2013, 96(1): 342-348.IF=6.044, top期刊
8. Sidi Li, Ning Chen, Yang Li, Xueping Li, Qi Zhan, Jiamin Ban,Jin Zhao*, Xin Hou*, Xubo Yuan*. Metal-Crosslinked ?-poly-L-lysine Tissue Adhesives with High Adhesive Performance: Inspiration from Mussel Adhesive Environment. International Journal of Biological Macromolecules,2020, doi: 10.1016/j.ijbiomac.2019.10.257. IF=4.731
9.Sidi Li, Ning Chen, Yang Li,Jin Zhao*, Xin Hou, Xubo Yuan. Environment-Dependent Adhesive Behaviors of Mussel-Inspired Coordinate-Crosslinked Bioadhesives. Macromolecular Materials and Engineering,2020, **. IF=3.038
10. Ying Du, Xin Hou*,Jin Zhao*, Xubo Yuan. Effect of Neutralization on Physicochemical/Mechanical Properties of Hydroxypropylmethylcellulose Acetate Succinate. Materials Chemistry and Physics,2020, 249:122963.IF=2.781
11. Sidi Li, Jianwei Wang, Mingming Ye, Xue Li, Ning Chen, Xueping Li, Yunde Liu, Xin Hou,Jin Zhao*, Zhenduo Cui, Xubo Yuan. Matricryptic Peptide-Inspired Hydrogels for Promoting Osteogenic Differentiation. International Journal of Polymeric Materials and Polymeric Biomaterials,2019, 68(7): 384-395. IF=2.263
12. Yu Bai, Sidi Li, Xueping Li, Xing Han, Yang Li,Jin Zhao*, Juntao Zhang*, Xin Hou, Xubo Yuan. An Injectable Robust Denatured Albumin Hydrogel Formed via Double Equilibrium Reactions. Journal of Biomaterials Science-Polymer Edition,2019, 30(8): 662-678. IF=2.121
13. Xueping Li, Qi Zhan, Hongzhao Qi, Donglin Han, Yaoyao Qin, Ning Chen, Lixia Long,Jin Zhao*, Xin Hou, Xubo Yuan*, Xianjin Yang. Paclitaxel Formulation with Stable Sustained-Release Behavior and Its Biological Safety Evaluation. Science China Technological Sciences,2019, 62(7): 1151-1159. IF=2.18
14. Li Sidi, Wang Jianwei, Song Lifeng, Zhou Yalin,Zhao Jin*, Hou Xin, Yuan Xubo. Injectable PAMAM/ODex Double-Crosslinked Hydrogels with High Mechanical Strength. Biomedical Materials,2017, 12 (1): 15012. IF=3.44
15. Qi Hongzhao, Jia Huanhuan, Sang Jimeng, Ren Yu*,Zhao Jin*, Hou Xin, Yuan Xubo. Using Endogenous Ligands for Direct Superparamagnetic Nanoparticle Cluster-Based Body Fluid Exosome Separation. RSC Advances,2017, 7(5): 2926-2933. IF=3.049
16. Lixia Long,Jin Zhao*, Ke Li, Ligang He, Xiaomin Qian, Limei Wang, Xinqi Yang, Jinjin Sun, Yu Ren, Chunsheng Kang*, Xubo Yuan*. Synthesis of Star-Branched PLA-b-PMPC Copolymer Micelles as Long Blood Circulation Vectors to Enhance Tumor-Targeted Delivery of Hydrophobic Drugsin vivo. Materials Chemistry and Physics.2016(1): 184-194. IF=2.781
17. Mingming Ye, Rui Jiang, Jin Zhao*, Juntao Zhang, Xubo Yuan, Xiaoyan Yuan, In Situ Formation of Adhesive Hydrogels Based on PL with Laterally Grafted Catechol Groups and Their Bonding Efficacy to Wet Organic Substrates, Journal of Materials Science: Materials in Medicine,2015, 26(12): 273, IF=2.467
18. Yalin Zhou, Wei Nie,Jin Zhao*, Xiaoyan Yuan, Rapidly in Situ Forming Adhesive Hydrogel Based on A PEG-Maleimide Modified Polypeptide Through Michael Addition, Journal of Materials Science: Materials in Medicine,2013, 24(10): 2277-2286. IF=2.467
l 主要论著：
Jin Zhao. “Chapter 6 -Chitosan Based Gels for Drug Delivery System” of the book “Chitosan-Based Hydrogels: Functions and Applications (Edited by Kangde Yao, et al)”, Taylor and Francis Group, CRC Press, 1 edition (July 28, 2011) (ISBN-13: 45)