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天津大学化工学院导师教师师资介绍简介-陈 涛

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陈 涛现任职称/职务:教授,博导
通讯地址:津南区雅观路135号,天津大学54楼-256
电子邮箱:chentao@tju.edu.cn
办公电话:**
研究方向: 主要研究方向为生物反应工程、代谢工程和合成生物学,主要采用代谢工程方法系统优化微生物细胞性能,或采用合成生物技术构建优良微生物底盘细胞与基因元件,实现生物合成途径的优化,重点致力于开发重要生物基化学品、药物及天然产物的生物反应与加工过程。
学术网页链接:

1.https://publons.com/researcher/**/tao-chen/
2.https://www.researchgate.net/profile/Tao_Chen61







陈 涛现任职称/职务:教授,博导
通讯地址:津南区雅观路135号,天津大学54楼-256
电子邮箱:chentao@tju.edu.cn
办公电话:**
研究方向: 主要研究方向为生物反应工程、代谢工程和合成生物学,主要采用代谢工程方法系统优化微生物细胞性能,或采用合成生物技术构建优良微生物底盘细胞与基因元件,实现生物合成途径的优化,重点致力于开发重要生物基化学品、药物及天然产物的生物反应与加工过程。
学术网页链接:

1.https://publons.com/researcher/**/tao-chen/
2.https://www.researchgate.net/profile/Tao_Chen61







陈 涛现任职称/职务:教授,博导
通讯地址:津南区雅观路135号,天津大学54楼-256
电子邮箱:chentao@tju.edu.cn
办公电话:**
讲授课程: 本科生专业课《基因工程操作原理》
本科生专业实验课《基因工程技术实验》
研究生选修课《系统代谢工程与合成生物技术》
研究生学位课《高等生物反应工程》








陈 涛现任职称/职务:教授,博导
通讯地址:津南区雅观路135号,天津大学54楼-256
电子邮箱:chentao@tju.edu.cn
办公电话:**
学术兼职: 国际代谢工程学会(IMES)会员,中国化工学会会员,中国微生物学会会员;天津微生物学会监事
国家自然科学基金评审人,教育部学位与研究生教育评估网评专家;
国际期刊Frontiers inBioengineering and Biotechnology,associate editor;
Metabolic Engineeing, Biotechnology for Biofuels,Bioresource Technology,ACS Synthetic Biology,Biotechnology and Bioengineering, Micirobial Cell Factories, Journal of Biotechnology,Biotechnology Journal,Current Microbiology、生物工程学报,化工学报、化学进展等国内外学术期刊审稿人。







陈 涛现任职称/职务:教授,博导
通讯地址:津南区雅观路135号,天津大学54楼-256
电子邮箱:chentao@tju.edu.cn
办公电话:**
学术成就: 作为项目负责人在本研究领域先后承担国家重点研发计划、国家自然科学基金, 973项目子课题等6项国家级项目和多项省部级和校企合作项目。在包括Metabolic Engineering,Green Chemistry , ACS Synthetic BiologyBiotechnology and Bioengineering 等在内的主流期刊上发表SCI论文100余篇,他引1500余次,H 因子21(Web of Science)。授权国家发明专利10余项,主编(译)教材两部。主要学术成就如下:
1.工业微生物的系统代谢工程
基于系统生物学研究进行工业微生物菌种的改造:包括建立基因组尺度代谢网络模型及模拟优化生物合成途径,基因组尺度的基因突变分析、基因型-表型关系分析、转录组及代谢通量分析等,在系统水平上对工业微生物的遗传、生理和代谢特征进行表征和机理解析,并在此基础上针对性的定位代谢工程的遗传修饰靶标和修饰策略,显著提升工业生产菌株的生产性能。
2. 重要模式微生物的基因组编辑技术
针对E.coli, B.subtilis等多种模式微生物建立了包括CRISPR-Cas9系统在内的多种高效基因组编辑系统,其中大肠杆菌的CRISPR-Cas9系统可进行快速、高效、可循环的基因组编辑,为大规模基因组工程提供了极有价值的工具,首次利用该技术针对b-胡萝卜素合成途径中的33个相关基因的表达进行大规模的组合优化,构建了高产β-胡萝卜素的代谢工程菌株,该成果突破了复杂代谢途径的大规模基因组修饰的难题,开发的基因编辑系统提交给Addgene(http://www.addgene.org),向国内外研究者无偿提供200余次,在国内外产生了重要的学术影响。
3).重要平台化学品高性能微生物细胞工厂
木质纤维素的高效利用是绿色生物制造的研究热点之一,而其中戊糖的高效利用是其中的主要挑战,我们结合代谢进化和代谢工程手段深度解析木糖高效利用和转化的代谢机理,挖掘和测试相关的基因元件,构建了具有高效木糖利用途径的底盘细胞。并在此基础上解析平台化学品丁二酸、手性2,3-丁二醇和手性3-羟基丁酮高效合成的代谢机理、优化合成途径,开发出利用木聚糖、纤维素水解液等廉价底物高效合成上列平台化学品的细胞工厂及相关生产工艺,这些细胞工厂的主要技术指标均达到国际领先或先进水平,显著提高了其生物加工过程的经济性,部分产品及工艺成功在企业中试放大。








陈 涛现任职称/职务:教授,博导
通讯地址:津南区雅观路135号,天津大学54楼-256
电子邮箱:chentao@tju.edu.cn
办公电话:**
科研项目: 国家重点研发计划:高版本嗜盐模式微生物底盘细胞的构建
国家自然科学基金面上项目:大肠杆菌微氧产3-羟基丙酸代谢工程研究
国家自然科学基金面上项目:枯草芽孢杆菌基因组微氧代谢木糖机理及产乙偶姻代谢工程研究
国家自然科学基金面上项目:枯草芽孢杆菌基因组最小化的研究
973子课题:生物基材料合成途径的DNA模块设计与组装
973子课题:代谢网络与调控网络构建分析与模拟设计
天津市科委基金:枯草芽孢杆菌生产2,3-丁二醇的代谢工程研究
国家自然科学基金青年基金:基于高产核黄素枯草芽孢杆菌全基因组突变分析的逆向代谢工程研究









陈 涛现任职称/职务:教授,博导
通讯地址:津南区雅观路135号,天津大学54楼-256
电子邮箱:chentao@tju.edu.cn
办公电话:**
论著专利: 主要论著



详见:https://publons.com/researcher/**/tao-chen/
https://www.researchgate.net/profile/Tao_Chen61

2018
1.YMao, G Li, Z Chang, R Tao, Z Cui, Z Wang*, Y Tang, T Chen*, X Zhao. Metabolicengineering of Corynebacterium glutamicum for efficient production of succinatefrom lignocellulosic hydrolysate. Biotechnologyfor biofuels 11 (1), 95.
2. DLiu, Z Mao, J Guo, L Wei, H Ma, Y Tang, TChen, Z Wang*, X Zhao. Construction,Model-Based Analysis, and Characterization of a Promoter Library for Fine-TunedGene Expression inBacillus subtilis. ACS synthetic biology 7 (7), 1785-1797.
3. Guanglu Wang, Ting Shi, Tao Chen, Xiaoyue Wang,Yongcheng Wang, Dingyu Liu, Jiaxin Guo, Jing Fu, Lili Feng, Zhiwen Wang*,Xueming Zhao. Integrated whole-genome and transcriptome sequence analysis reveals thegenetic characteristics of a riboflavin-overproducingBacillus subtilis. MetabolicEngineering. 2018, 48:138-149
4. SZhang, D Liu, Z Mao, Y Mao, H Ma, T Chen,X Zhao, Z Wang. Model-based reconstruction ofsynthetic promoter library inCorynebacterium glutamicum. Biotechnology letters 40 (5), 819-827.
5. PYan, Y Wu, L Yang, Z Wang, T Chen*.Engineering genome-reducedBacillus subtilisforacetoin production from xylose. Biotechnologyletters 40 (2), 393-398.
6. XLi, C Huang, X Yu, S Liu, Z Wang, YJ Tang, TChen*. Highly Efficient HemicelluloseUtilization for Acetoin Production by an EngineeredBacillus Subtilis.Journal of Chemical Technology &Biotechnology.2018.
7. ZCui, Y Mao, Y Zhao, C Chen, Y Tang, TChen, H Ma*, Z Wang*. Journal ofChemical Technology & Biotechnology.2018
8. KQHong, DY Liu, T Chen, ZW Wang*. Recent advances in CRISPR/Cas9 mediated genome editinginBacillus subtilis. WorldJournal of Microbiology and Biotechnology 34 (10), 153.





2017
1.Y Mao, J Fu, R Tao, C Huang, Z Wang*, YJTang, T Chen*, X Zhao. Systematic metabolic engineering of Corynebacteriumglutamicum for industrial-level production of optically pure D-(-)-Acetoin. Green Chemistry,2017,19, 5691-5702.
2. G Huo, Y Zhu, Q Liu, R Tao, N Diao, Z Wang, T Chen*. Metabolic engineering of an E.coli ndh knockout strain for PHB production from mixed glucose‐xylose feedstock.Journal of Chemical Technology and Biotechnology.2017,92(10):2739-2745.
3.QYuan, T Huang, P Li, T Hao, F Li, H Ma*, Z Wang*, X Zhao, T Chen*, I. Goryanin. Pathway-Consensus Approach toMetabolic Network Reconstruction for Pseudomonas putida KT2440 by SystematicComparison of Published Models. PloS one,2017, 12 (1),e**.
4. Y Zhang, P Kang, S Liu, Y Zhao, Z Wang, T Chen*. glyA gene knock-out in Escherichia coli enhancesL-serine production without glycine addition., Biotechnology andBioprocess Engineering. 2017, 22 (4), 390-396.
5. T Liu, YY Yu, T Chen, WN Chen. Asynthetic microbial consortium of shewanella and bacillus for enhancedgeneration of bioelectricity. Biotechnology and bioengineering.2017, 114(3), 526-532.
6. Z Li, J Meng, W Wang, Z Wang, M Li, T Chen, CJ Liu. The room temperature electron reduction for thepreparation of silver nanoparticles on cotton with high antimicrobial activity.Carbohydrate Polymers.2017, 161, 270-276.
7.Y Zou, T Chen, L Feng, S Zhang, D Xing, ZWang*. Enhancement of 5-aminolevulinic acidproduction by metabolic engineering of the glycine biosynthesis pathway inCorynebacterium glutamicum. Biotechnology Letters, 2017, 39(9):1369-1374.
8. AKalantari, T Chen, B Ji, IA Stancik, V Ravikumar, D Franjevic, C. Saulou-Bérion, A. Goelzer, and Ivan Mijakovic..Conversion of glycerol to 3-hydroxypropanoic acid bygenetically engineered Bacillus subtilis. Frontiers inmicrobiology.2017, 8:638.


2016
1.J Fu, G Huo, LFeng, Y Mao, Z Wang*, H Ma, T Chen*, X Zhao. Metabolic engineering of Bacillussubtilis for chiral pure meso-2, 3-butanediol production.Biotechnologyfor biofuels. 2016.9:90
2.Lili Feng, YaZhang, Jing Fu, Tao Chen,Xueming Zhao,Zhiwen Wang*,Metabolicengineering of Corynebacterium glutamicum for efficient production of5-aminolevulinic acid. Biotechnology and Bioengineering.2016.113(6):1284-1293.
3.Y Li, X Zhu, X Zhang, J Fu, Z Wang, T Chen*, X Zhao. Characterization ofgenome-reduced Bacillus subtilis strains and their application for theproduction of guanosine and thymidine. Microbial cell factories. 2016.15:94.
4.Bo Zhang, Xin-liLi, Fu Jing, Ning Li, Zhiwen Wang*,Ya-jie Tang, TaoChen*.Production of Acetoin through Simultaneous Utilization of Glucose,Xylose, and Arabinose by Engineered Bacillus subtilis. PloS one. 2016,11 (7), e**.
5.JH Yu, LW Zhu, ST Xia, HM Li, YL Tang, XH Liang, TChen, YJ Tang*.Combinatorial optimization of CO2 transport andfixation to improve succinate production by promoter engineering. Biotechnology& Bioengineering. 2016,113(7):1531-1541.
6.S Liu, P Kang, ZCui, Z Wang, T Chen*. Increased riboflavin production by knockout of6-phosphofructokinase I and blocking the Entner–Doudoroff pathway inEscherichia coli.Biotechnology letters. 2016.38(8):1307-1314.
7.Qinglong Meng, Yanfei Zhang, Xiaozhi Ju, Chunling Ma,Hongwu Ma*, Jiuzhou Chen, Ping Zheng, Jibin Sun, Jun Zhu, Yanhe Ma, XuemingZhao, Tao Chen*.Production of 5-aminolevulinic acid by cell freemulti-enzyme catalysis. Journal of Biotechnology. 2016;226:8–13.
8.Xiaoyan Yang, Qianqian Yuan, Yangyang Zheng, HongwuMa*, Tao Chen, Xueming ZhaoAn engineered non-oxidative glycolysispathway for acetone production in Escherichia coli. Biotechnology Letters.2016, 38(8):1359-1365.
9.X Wang, G Wang,X Li, J Fu, T Chen, Z Wang*, X Zhao. Directed evolution of adenylosuccinatesynthetase from Bacillus subtilis and its application in metabolic engineering.Journal of biotechnology. 2016.231:115-121.
10.J Meng, B Wang, D Liu, T Chen, Z Wang*, X Zhao.High-yield anaerobic succinate production by strategically regulating multiplemetabolic pathways based on stoichiometric maximum in Escherichia coli.Microbial Cell Factories. 2016;15:141.
11.余君涵,马雯雯,王智文*,陈涛,赵学明.人工合成启动子文库研究进展.微生物学通报.2016;43(1):198-204.
12.徐志博,林振泉,陈涛*.大肠杆菌中核黄素的生物合成途径改造及生产.化学工业与工程.2016;33(2):114-119.

2015
1.Yifan Li;Zhenquan Lin; Can Huang; Yan Zhang; Zhiwen Wang; Chen Tao*, Xueming Zhao.Metabolicengineering of Escherichia coli using CRISPR-Cas9 meditated genome editing.Metabolic Engineering. 2015,31:13-21.27.
2. Zhang,Bo;Li, Ning;Wang,Zhiwen;Tang, Ya-Jie;Chen,Tao*Zhao, Xueming, Inverse metabolic engineering of Bacillussubtilis for xylose utilization based on adaptive evolution and whole-genomesequencing, Applied Microbiology and Biotechnology, 99(2), pp 885-896,2015/2/1.
3.Wang Xiaoyue,Wang Baiyun, Wang Zhiwen*, Chen Tao, Zhao Xueming. The research progress ofprotein directed evolution. Prog. Biochem. Biophys. 2015,42(2):123-131.
4.Ma,Wenwen;Wang, Xiaoyue;Mao, Yufeng;Wang,Zhiwen*;Chen, Tao;Zhao, Xueming, Development of amarkerless gene replacement system in Corynebacterium glutamicumusingupp as a counter-selection marker., Biotechnology Letters,.2015.37(3):609-617.
5.Zhibo Xu,Zhenquan Lin, ZhiwenWang, Tao Chen*. Improvement of the riboflavin productionby engineering the precursors biosynthesis pathways inEscherichiacoli.Chinese Journal of Chemical Engineering. 2015,23(11):1834-1839.
6.Zhenquan Lin,Yan Zhang, Qianqian Yuan,, Qiaojie Liu, Yifan Li, Zhiwen Wang,Hongwu Ma*, Tao Chen*, Xueming Zhao. Metabolic engineering ofEscherichiacolifor poly(3-hydroxybutyrate) production via threoninebypass.Microbial Cell Factories,2015,14:185.
7.QinglongMeng,YanfeiZhang,ChunlingMa,HongwuMa*,XuemingZhao,TaoChen.Purificationand functional characterization of thermostable 5-aminolevulinic acidsynthases.Biotechnology Letters,2015, 37(11):2247-2253.
8.王永成,陈涛,石婷,王智文*,赵学明.嘌呤核苷及其衍生物的代谢工程,中国生物工程杂志,2015,35(5):87-95.
9.刘晓霏,付晶,霍广鑫,章博,王智文,陈涛*,生物法制备平台化合物乙偶姻的最新研究进展,中国生物工程杂志,2015,35(10):91-99.
10.朱旭军,李一凡,李杨,付晶,王智文,陈涛*.陈涛枯草芽孢杆菌无标记遗传操作技术研究进展2015, 42(12):2440?2447.
11.李思梦;李晓静;陈涛*,代谢工程方法改造大肠杆菌生产胸苷,生物工程学报, 31:01期, pp 105-114,2015.
12.赵学明,陈涛,王智文,《代谢工程》,高等教育出版社,北京,2015.

2014
1 QiaojieLiu; Zhenquan Lin; Yan Zhang; YifanLi; Zhiwen Wang; Tao Chen*, Improvedpoly(3-hydroxybutyrate) production in Escherichia coli byinactivation of cytochrome bd-II oxidase or/andNDH-II dehydrogenase in low efficient respiratorychains., Journal of Biotechnology, 192 Pt A卷, pp 170-176, 2014/12/20.
2. YanZhang,Zhenquan Lin,Qiaojie Liu,Yifan Li,Zhiwen Wang,Hongwu Ma,Tao Chen*,XuemingZhao.Engineering of Serine-Deamination pathway, Entner-Doudoroff pathwayand pyruvate dehydrogenase complex to improve poly(3-hydroxybutyrate)production in Escherichia coli.Microbial Cell Factories.2014, 13(1):172.
3 NingLi; Bo Zhang; Zhiwen Wang; Ya-JieTang; Tao Chen*; Xueming Zhao, Engineering Escherichiacoli for fumaric acid production from glycerol., Bioresour Technol, 174C卷, pp 81-87,2014/10/7.
4. Fu, Jing;Wang, Zhiwen; Chen, Tao*; Liu, Weixi; Shi, Ting; Wang,Guanglu; Tang, Ya-jie; Zhao, Xueming, NADH plays the vital role forchiral pure D-(-)-2,3-butanediol production inBacillus subtilis under limited oxygen conditions., Biotechnology andBioengineering, 111(10), pp 2126-2131, 2014/10.
5. Ma,Xianghui; Zhang, Xinbo; Wang, Baiyun; Mao, Yufeng;Wang, Zhiwen*; Chen, Tao*; Zhao, Xueming, Engineeringmicroorganisms based on molecular evolutionary analysis: asuccinate production case study.,Evolutionary Applications, 7(8), pp 913-920, 2014/9.
6. WangBaiyun; Wang Xiaoyue; Wang Zhiwen*; ChenTao; Zhao Xueming, Redox Cofactor Metabolic Engineering withEscherichia coli, Progress in Chemistry, 26(9), pp 1609-1618, 2014/9.
7. Lin,Zhenquan; Xu, Zhibo; Li, Yifan; Wang,Zhiwen*; Chen, Tao*; Zhao, Xueming, Metabolicengineering of Escherichia coli for the production of riboflavin, MicrobialCell Factories, 13卷, 2014/7/16.2014,13:104
8. Shi,Ting; Wang, Yongcheng; Wang, Zhiwen*; Wang,Guanglu; Liu, Dingyu; Fu, Jing; Chen,Tao; Zhao, Xueming, Deregulation of purine pathway in Bacillussubtilis and its use in riboflavin biosynthesis, Microbial Cell Factories,13:101, 2014/7/15.
9.Wang,Guanglu; Bai, Ling; Wang, Zhiwen*; Shi, Ting; Chen,Tao; Zhao, Xueming, Enhancement of riboflavin production by deregulatinggluconeogenesis in Bacillus subtilis.,World Journal of Microbiology and Biotechnology, 30(6), pp 1893-1900,2014/6.
10.贾慧慧;李晓静;陈涛*;赵学明, 微生物发酵法生产L-丝氨酸及L-半胱氨酸研究进展, 中国生物工程杂志, 05期, pp 100-106,2014/5/15.
11. Yang,Jiangang; Wang, Zhiwen; Zhu, Nianqing; Wang, Baiyun; Chen, Tao*; Zhao, Xueming, Metabolic engineering of Escherichia coli andin silico comparing of carboxylation pathways for high succinate productivityunder aerobic conditions, Microbiological Research, 169(5–6), pp 432-440,2014/5.
12.马红武;刘会娟;朱年青;陈涛*, 代谢工程方法改造谷氨酸棒状杆菌生产乙偶姻, 天津大学学报(自然科学与工程技术版), 11期, pp 967-972,2014/4.
13. Zhu,Nianqing; Xia, Huihua; Yang, Jiangang; Zhao, Xueming; Chen, Tao*, Improved succinate production in Corynebacterium glutamicum byengineering glyoxylate pathway and succinate export system, BiotechnologyLetters, 36(3), pp 553-560, 2014/3.
14. 李桂莹;张新波;王智文*;石婷;陈涛;赵学明, 逆向代谢工程的最新研究进展, 生物工程学报, 08期, pp 1151-1163,2014/3.
15. TaoChen; Nianqing Zhu; Huihua Xia, Aerobic production of succinatefrom arabinose by metabolically engineered Corynebacterium glutamicum,Bioresource Technology, 151(5–6), pp 411-414, 2014/1.
16. 夏慧华;尹国民;朱年青;陈涛*, 谷氨酸棒杆菌生产琥珀酸的代谢工程研究进展, 微生物学通报, 05期, pp 943-949, 2014


2013
1.Hao, Tong;Han,Binbin;Ma, Hongwu;Fu, Jing;Wang, Hui;Wang, Zhiwen;Tang, Bincai; Chen,Tao*;Zhao, Xueming*, 2013, In silico metabolic engineering of Bacillus subtilisfor improved production of riboflavin, Egl-237, (R,R)-2,3-butanediol andisobutanol, Molecular Biosystems, 9(8), pp 2034-2044 (SCI, IF=3.350(2012))
2.Zhu,Nianqing;Xia, Huihua;Wang, Zhiwen;Zhao, Xueming;Chen, Tao*, 2013, Engineeringof Acetate Recycling and Citrate Synthase to Improve Aerobic SuccinateProduction in Corynebacterium glutamicum, PLos One, 8(4), (SCI,IF=3.730(2012)
3.刘维喜;付晶;章博;陈涛*, 2013, 微生物木糖代谢途径改造制备生物基化学品, 生物工程学报, (08), pp1161-1172
4.郑宗宝;赵美娜;陈涛*;赵学明, 2013, 基于重组策略的一体化生物加工过程最新进展, 生物工程学报, (10), pp1354-1362
5.顾群;李一凡;陈涛*, 2013, 合成生物系统的组合优化, 生物工程学报, (08), pp1064-1074
6.汤彬彩;郝彤;袁倩倩;陈涛;马红武*, 2013, 一种基于代谢网络分析最小化基因组的方法及其在大肠杆菌中的应用, 生物工程学报, (08), pp1173-1184
7.Li, Yifan;Gu,Qun;Lin, Zhenquan;Wang, Zhiwen;Chen, Tao*;Zhao, Xueming, 2013, MultiplexIterative Plasnnid Engineering for Combinatorial Optimization of MetabolicPathways and Diversification of Protein Coding Sequences, ACS SyntheticBiology, 2(11), pp 651-661 (SCI, IF=(2012))
8.Li-Wen Zhu;Xiao-HongLi;Lei Zhang;Hong-Mei Li;Jian-Hua Liu;Zhan-Peng Yuan;Tao Chen;Ya-Jie Tang*,2013, Activation of glyoxylate pathway without the activation of its relatedgene in succinate-producing engineered Escherichia coli, Metabolic Engineering,20(4), pp 9-19 (EI, SCI, IF=6.859(2012))
9.Shi, Ting;Wang,Guanglu;Wang, Zhiwen*;Fu, Jing;Chen, Tao;Zhao, Xueming, 2013, Establishment ofa Markerless Mutation Delivery System in Bacillus subtilis Stimulated by aDouble-Strand Break in the Chromosome, PLos One, 8(11), (SCI, IF=3.730(2012))
10.Li, Ning;Zhang,Bo;Chen, Tao*;Wang, Zhiwen;Tang, Ya-jie;Zhao, Xueming, 2013, Directed pathwayevolution of the glyoxylate shunt in Escherichia coli for improved aerobicsuccinate production from glycerol, Journal of Industrial Microbiology andBiotechnology, 40(12), pp 1461-1475 (SCI, IF=2.321(2012))
11.Liu, Rui-Sang;Zhou, Huan;Li, Hong-Mei;Yuan, Zhan-Peng;Chen, Tao;Tang, Ya-Jie*, 2013,Metabolism of L-methionine linked to the biosynthesis of volatile organicsulfur-containing compounds during the submerged fermentation of Tubermelanosporum, Applied Microbiology and Biotechnology, 97(23), pp 9981-9992 (EI,SCI, IF=3.689(2012))
12.Tao Chen*;WeixiLiu;Jing Fu;Bo Zhang;Ya-jie Tang, 2013, Engineering Bacillus subtilis foracetoin production from glucose and xylose mixtures, Journal of Biotechnology,168(4), pp 499-505 (EI, SCI, IF=3.183(2012))


2012
1.Zheng, Zongbao; Chen, Tao*;Zhao, Meina;Wang, Zhiwen;Zhao, Xueming, 2012, EngineeringEscherichia coli for succinate production from hemicellulose via consolidatedbioprocessing, Microbial Cell Factories, 11, (EI, SCI, IF=3.5520(2011),
2.Wang,Qingzhao;Chen, Tao; Zhao, Xueming;Chamu, Jauhleene, 2012, Metabolic engineeringof thermophilic Bacillus licheniformis for chiral pure D-2,3-butanediolproduction, Biotechnology and Bioengineering, 109(7), pp 1610-1621 (SCI,IF=3.9460(2011)
3.Wang, Meng;Fu,Jing; Zhang, Xueyu;Chen, Tao*, 2012, Metabolic engineering of Bacillus subtilisfor enhanced production of acetoin, Biotechnology Letters, 34(10), pp 1877-1885(EI, SCI, IF=1.853(2012)
4.付晶;王萌;刘维喜;陈涛*;FuJingWangMengLiuWeixiChenTao(KeyLaborato,2012, Latest Advances of Microbial Production of 2,3-Butanediol, Progress inChemistry, 24(11), pp 2268-2276 (SCI, IF=0.670(2012))


2008-2011
1.陈涛,赵学明 译,《生物过程过程:基本概念》,化学工业出版社,北京,2008.
2.Shi Shuobo, ShenZuo, Chen Xun, Chen Tao*, Zhao Xueming. Increased production of riboflavin bymetabolic engineering of the purine pathway in Bacillus subtilis, BiochemicalEngineering Journal. 2009,46:28-33.
3.Shi Shuobo, ChenTao(共同1作), Chen Xun, ZhaoXueming*. Transcriptome analysis guided metabolic engineering of Bacillussubtilis for riboflavin production, Metabolic Engineering, 2009,11:243-252. (EI,SCI, IF=6.859(2012))
4.史硕博,陈涛*,赵学明,转录组平台技术及其在代谢工程中的应用,生物工程学报,2010,26(9):1187-1198.
5.Duan Yunxia, Chen Tao*, Chen Xun, Wang Jingyu, Zhao Xueming, Enhanced riboflavin productionby expressing heterologous riboflavin operon from B. cereus ATCC14579 inBacillus subtilis. Chinese Journal of Chemical Engineering. 2010,18 (1):129-136.
6.Wang Zhiwen, MaXiangHui, Chen Xun, Zhao Xueming, Chen Tao*. Current method and advances inmicrobial metabolomics. Progress in Chemistry. 2010,22 (1): 163-172.
7.Zhiwen Wang, TaoChen*, Xianghui Ma, Zhuo Shen, Xueming Zhao. Enhancement of riboflavinproduction with Bacillus subtilis by expression and site-directed mutagenesisof zwf and gnd gene from Corynebacterium glutamicum. Bioresource Technology.2011, 102(4):3934-3940.
8.赵学明, 陈 涛. 合成生物学: 进展和展望,《2011年科学发展报告》, 2011,P14-27. 科学出版社.

专利:授权国家发明专利10项,申请国家发明专利10余项








陈 涛现任职称/职务:教授,博导
通讯地址:津南区雅观路135号,天津大学54楼-256
电子邮箱:chentao@tju.edu.cn
办公电话:**
合作交流: 课题组成员:王智文 副教授
目前课题组和中科院工业生物技术研究所马红武研究员,发酵工程教育部重点实验室(湖北工业大学)汤亚杰教授进行研究生的联合培养。





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