李　凤现任职称/职务：副教授
通讯地址：天津海河教育园区雅观路135号天津大学北洋园校区54号教学楼
电子邮箱：fengli2018@tju.edu.cn
办公电话：
研究方向: DNA/聚合物杂化动态组装体系的构建和生物应用

实验室链接

---

李　凤现任职称/职务：副教授
通讯地址：天津海河教育园区雅观路135号天津大学北洋园校区54号教学楼
电子邮箱：fengli2018@tju.edu.cn
办公电话：
研究方向: DNA/聚合物杂化动态组装体系的构建和生物应用

实验室链接

---

李　凤现任职称/职务：副教授
通讯地址：天津海河教育园区雅观路135号天津大学北洋园校区54号教学楼
电子邮箱：fengli2018@tju.edu.cn
办公电话：
讲授课程: 《生物化工前沿知识讲座》
《纳米生物技术概论》
实验室链接

---

李　凤现任职称/职务：副教授
通讯地址：天津海河教育园区雅观路135号天津大学北洋园校区54号教学楼
电子邮箱：fengli2018@tju.edu.cn
办公电话：
学术成就: 1. Feng Li+, Shuai Li+,Xiaocui Guo, Yuhang Dong, Chi Yao, Yangping Liu, Yuguang Song, Xiaoli Tan,Lizeng Gao, Dayong Yang*. Chiral carbondots mimicking topoisomerase I to enantioselectively mediate topologicalrearrangement of supercoiled DNA. Angew. Chem. Int. Ed. 2020.
2. Feng Li, Tianyu Li,Chenxing Sun, Jiahao Xia, Yang Jiao, and Huaping Xu*. “Selenium-Doped CarbonQuantum Dots (Se-CQDs) for Free Radical Scavenging.”Angew. Chem. Int. Ed.2017,129, 10042-10046.
3. Feng Li+, Yiye Li+,Xiao Yang, Xuexiang Han, Yang Jiao, Taotao Wei, Dayong Yang, Huaping Xu*,Guangjun Nie*. Highly Fluorescent Chiral N-S-Doped Carbon Dots from CysteineAffect Cellular Energy Metabolism. Angew. Chem. Int. Ed.2018.9,2377-2382.
4. Xiaocui Guo+, Feng Li+,Lihui Bai, Wenting Yu, Xue Zhang, Yi Zhu, Dayong Yang*. Gene Circuit Compartment on Nano-interface Facilitates Cascade GeneExpression. J. Am. Chem. Soc. 2019.
5 Feng Li+, JianpuTang+, Jinhui Geng, Dan Luo, Dayong Yang*. Polymeric DNA Hydrogel: Design, Synthesis and Applications. Progress in Polymer Science,2019.
6. Feng Li+, Xue Zhang+, Shuxian Hu+, Zhaoyue Lv, Jigang Lv, Wenting Yu,Xihan Xu, Dayong Yang*. BioinspiredMechanically Responsive Hydrogel upon Redox Mediated by Dynamic Coordinationbetween Telluroether and Platinum Ions. Chemistry of Materials, 2020.
7. Feng Li+, WentingYu+, Xue Zhang, Xiaocui Guo, Xihan Xu, Xiaolei Sun, Dayong Yang*. Preparation of Biomimetic Gene Hydrogel viaPolymerase Chain Reaction for Cell-Free Protein Expression. Science China Chemistry, 2019.
8. Feng Li, Xiao Zhao,Hai Wang, Ruifang Zhao, Tianjiao Ji, He Ren, Gregory J. Anderson, GuangjunNie*, and Jihui Hao*. “Multiple Layer-by-layer Lipid-polymer HybridNanoparticles for Improved FOLFIRINOX Chemotherapy in Pancreatic Tumor Models.”Adv.Funct. Mater. 2015,25, 788-798.
9. Feng Li, Jing Wang,Shuqing Sun*, Hai Wang, Zhiyong Tang, and Guangjun Nie*. “Facile Synthesis ofpH-sensitive Germanium Nanocrystals with High Quantum Yield for IntracellularAcidic Compartment Imaging.” Small, 2015, 16, 1954-1961.
10. Feng Li+, YuhangDong+, Zhikun Zhang+, Man Lv+, Zhi Wang, Xinhua Ruan, Dayong Yang*. A recyclable biointerface based oncross-linked branched DNA nanostructures for ultrasensitive nucleic aciddetection. Biosensors andBioelectronics, 2018, 117, 562-566.
11. Xiao Zhao+, Feng Li+,Yiye Li, Hai Wang, He Ren, Jing Chen, Guangjun Nie*, and Jihui Hao*.“Co-delivery of HIF1α siRNA and Gemcitabine via Biocompatible Lipid-polymerHybrid Nanoparticles for Effective Treatment of Pancreatic Cancer.” Biomaterials, 2015, 46, 13-25.
12. Feng Li, Wei Cao,Lu Wang, and Huaping Xu*. “Near-Infrared Light Stimuli-responsive SynergisticTherapy Nanoplatforms Based on the Coordination of Tellurium-containing BlockPolymer and Cisplatin for Cancer Treatment.” Biomaterials, 2017, 133,208-218.
13. Feng Li, Jing Wang,Yuming Lai, Chong Wu, and Shuqing Sun*. “Ultrasensitive and Selective Detectionof Copper (II) and Mercury (II) Ions by Dye-Coded Silver Nanoparticle-BasedSERS Probes.”Biosens. Bioelectron. 2013, 39, 82-87.
14. Qianmin Ma+, Feng Li+,Jianpu Tang, Ke Meng, Xihan Xu, Dayong Yang*. Luminescent ultralong microfiber prepared via supramolecularself-assembly of lanthanide and thymidine in water. Chemistry-A European Journal, 2018, 24, 18890-18896. DOI:10.1002/chem..
15. Feng Li*, DayongYang, Huaping Xu*. Nonmetal heteroatomdoped carbon dots: synthesis and property. Chemistry-A European Journal, 2018, 24, 1-13.DOI:10.1002/chem..
16 .Feng Li, Tianyu Li,Xuexiang Han, Hao Zhuang, Guangjun Nie, and Huaping Xu*. “NanomedicineAssembled by Coordinated Selenium-Platinum Complexes Can Selectively InduceCytotoxicity in Cancer Cells by Targeting the Glutathione Antioxidant DefenseSystem.” ACS Biomater-SCI. Eng. 2019.
17. Chenxing Sun, Shaobi Ji, FengLi*, and Huaping Xu*. “Diselenide-Containing Hyperbranched Polymer withLight-Induced Cytotoxicity.” ACS Appl. Mater. Interfaces, 2017, 9,12924-12929.
18. Jiaojiao Zhang+, FengLi+, Dayong Yang*. DNA: Fromcarrier of genetic information to polymeric materials. Transactions of Tianjin University,2019.
19. Xiaocui Guo, Lihui Bai, FengLi, Wilhelm Huck, Dayong Yang*. BranchedDNA architectures via PCR‐based assembly as gene compartment for cell‐free geneexpression reactions. ChemBioChem,2019. DOI: 10.1002/cbic..
20. Huaixin Zhao+, Chunxia Liu+, Zi Gu, Luxi Dong, Feng Li, Chi Yao, Dayong Yang*. Persistent luminescentnanoparticles containing hydrogel for targeted, sustained and autofluorescence-freetumor metastasis imaging. Nano Letters, 2019.
21. Lu Yang+, Chi Yao+, FengLi, Yuhang Dong, Zhikun Zhang, and Dayong Yang*. Synthesis of branched DNA scaffolded super-nanoclusters with enhancedantibacterial performance. Small,2018, 14, **.
22. Jiahao Xia, Feng Li,Shaobo Ji, and Huaping Xu*. “Selenium-functionalized Graphene Oxide that CanModulate the Balance of Reactive Oxygen Species.” ACS Appl. Mater. Interfaces,2017, 9, 21413-21421.
23. Yuming Lai, Feng Li,and Shuqing Sun*. “Controlled Surface Enhanced Resonance Raman Scattering(SERRS) in Biological Environment.” Integr. Ferroelectr. 2013, 146,88-98.
24. Tianyu Li, Feng Li,Wentian Xiang, Yu Yi, Yuyan Chen, Liang Cheng, Zhuang Liu,and Huaping Xu*.“Selenium-containing Amphiphiles Reduced and Stabilized Gold Nanoparticles:Kill Cancer Cells via Reactive Oxygen Species.” ACS Appl. Mater. Interfaces, 2016, 8, 22106-22112.
25. Wei Cao, Feng Li,Ruofan Chen, and HuapingXu*. “Tellurium-Containing Nanoparticles for ControlledDelivery of Cisplatin Based on Coordination Interaction.” RSC Advances, 2016, 6, 94033-94037.
26. Fuqiang Fan, Lu Wang, FengLi, Yu Fu, and Huaping Xu*. “Stimuli-Responsive Layer-by-LayerTellurium-Containing Polymer Films for Combination of Chemotherapy andPhotodynamic Therapy.” ACS Appl. Mater. Interfaces, 2016, 8, 17004-17010.
27. Weiqiang Zhou, Lu Wang, FengLi, Weina Zhang, Wei Huang, Fengwei Huo*, andHuapingXu*.“Selenium-containing Polymer@metal-organic Frameworks Nanocompositesas Efficientmulti-responsive Drug Delivery System.”Adv. Funct. Mater. 2017, 27,**.
28. Lu Yang, Chi Yao, FengLi, Yuhang Dong, Zhikun Zhang, and Dayong Yang*. Synthesis of Branched DNAScaffolded Super-nanoclusters with Enhanced Antibacterial Performance. Small,2018, 16,**.
29. Tianyu Li, Wentian Xiang, FengLi, and Huaping Xu.Self-assembly regulated anticancer activity of platinumcoordinated selenomethionine. Biomaterials, 2017, 157, 17-25.
30. Hai Wang, Ruifang Zhao, Yiye Li, Huiyu Liu, FengLi, Yuliang Zhao, and Guangjun Nie*. “Aspect Ratios of Gold NanoshellCapsules Mediated Melanoma Ablation by Synergistic Photothermal Therapy andChemotherapy.” Nanomedicine, 2015, 12, 439-448.
31. Suping Li, Yinlong Zhang, Jing Wang, Ying Zhao, Tianjiao Ji,Xiao Zhao, Yanping Ding, Xiaozheng Zhao, Ruifang Zhao, Feng Li, Xiao Yang, Shaoli Liu, Zhaofei Liu, Jianhao Lai, Andrew K.Whittaker, Gregory J. Anderson, Jingyan Wei, and Guangjun Nie*.Nanoparticle-mediated Local Depletion of Tumour-associated Platelets DisruptsVascular Barriers and Augments Drug Accumulation in Tumours. Nature Biomed. Eng. 2017, 8, 667-679.

实验室链接

---

李　凤现任职称/职务：副教授
通讯地址：天津海河教育园区雅观路135号天津大学北洋园校区54号教学楼
电子邮箱：fengli2018@tju.edu.cn
办公电话：
科研项目: 国家自然科学基金“面上项目” 主持1项（在研）
国家自然科学基金“青年项目” 主持1项（在研)
天津市自然科学基金“青年项目” 主持1项（在研）
科技部重点研发计划 参与1项（在研）
北京市自然科学基金“青年项目” 主持1项（已结题）
中国博士后基金“面上项目” 主持1项（已结题）

实验室链接