卢文玉现任职称/职务：副教授/博导（生物化工）/生化系副主任
通讯地址：天津大学北洋园校区54-226
电子邮箱：wenyulu@tju.edu.cn
办公电话：**
研究方向:
研究方向：系统与合成生物学、生化工程
具体包括：围绕系统与合成生物学、代谢工程、生化工程、发酵工程领域的理论和技术研究，专注于重要活性天然产物等微生物药物、糖脂等生物化学品、石油烃降解菌等环境生物制剂的高效生物制造，凝练出“基于动态代谢途径调控的胞内生物合成”和“产品生产效能导向的细胞群体生化过程强化”两类关键科学与技术问题，从功能元器件挖掘、模块构建、代谢途径分析与代谢网络重构、细胞工厂构建、细胞群体生化过程强化和工程放大等多层次开展工作，形成了前沿探索、基础研究、工程放大及应用的全链条研究特色。

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卢文玉现任职称/职务：副教授/博导（生物化工）/生化系副主任
通讯地址：天津大学北洋园校区54-226
电子邮箱：wenyulu@tju.edu.cn
办公电话：**
研究方向:
研究方向：系统与合成生物学、生化工程
具体包括：围绕系统与合成生物学、代谢工程、生化工程、发酵工程领域的理论和技术研究，专注于重要活性天然产物等微生物药物、糖脂等生物化学品、石油烃降解菌等环境生物制剂的高效生物制造，凝练出“基于动态代谢途径调控的胞内生物合成”和“产品生产效能导向的细胞群体生化过程强化”两类关键科学与技术问题，从功能元器件挖掘、模块构建、代谢途径分析与代谢网络重构、细胞工厂构建、细胞群体生化过程强化和工程放大等多层次开展工作，形成了前沿探索、基础研究、工程放大及应用的全链条研究特色。

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卢文玉现任职称/职务：副教授/博导（生物化工）/生化系副主任
通讯地址：天津大学北洋园校区54-226
电子邮箱：wenyulu@tju.edu.cn
办公电话：**
讲授课程:
生物反应工程（本科生，专业必修，2008-）
生物工程技术原理（研究生，必修课，2010-）

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卢文玉现任职称/职务：副教授/博导（生物化工）/生化系副主任
通讯地址：天津大学北洋园校区54-226
电子邮箱：wenyulu@tju.edu.cn
办公电话：**
学术兼职:
美国微生物学会、美国生化与分子生物学学会、中国生物工程学会、中国微生物学会会员，中国药学会高级会员；BB等20余种期刊审稿人；国家自然科学基金化学部、生命学部项目、天津市科技支撑重点项目、内蒙古自然科学基金等项目评审专家。南开大学生科院生物与医药专业学位研究生校外导师。

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卢文玉现任职称/职务：副教授/博导（生物化工）/生化系副主任
通讯地址：天津大学北洋园校区54-226
电子邮箱：wenyulu@tju.edu.cn
办公电话：**
学术成就:
科研获奖：
2010年 教育部新世纪优秀人才
2019年 天津市科技进步二等奖
其他获奖：
2008年本科毕业（论文）优秀指导教师
2009年国家教学成果二等奖
2009年 天津市教学成果一等奖
2013年天津市教学成果一等奖
2015年 天津市优秀硕士学位论文指导教师
2011年天津大学优秀共产党员
2011年天津大学就业工作先进个人
2009年天大天久奖教金
2011年天津大学化工学院“科技创新先锋模范岗”
2012年天大宝舜奖教金
2017年 化工学院首届“我身边的好导师”

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卢文玉现任职称/职务：副教授/博导（生物化工）/生化系副主任
通讯地址：天津大学北洋园校区54-226
电子邮箱：wenyulu@tju.edu.cn
办公电话：**
科研项目:
主持完成国家自然科学基金面上项目（3项）、国家“973”计划子课题（2项）、国家科技支撑计划项目子课题、JS项目、教育部新世纪优秀人才项目、教育部博士点基金、天津市科技重大专项、天津市科技支撑重点项目（2项）、天津市海洋局项目、天津市自然科学基金面上项目等国家级、省部级课题14项，企业产学研合作项目10余项。

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卢文玉现任职称/职务：副教授/博导（生物化工）/生化系副主任
通讯地址：天津大学北洋园校区54-226
电子邮箱：wenyulu@tju.edu.cn
办公电话：**
论著专利:
2007年留校工作以来发表文章50余篇，其中以第一或通讯作者发表SCI文章40余篇：
2019
1. Zhao Fanglong, Bai Peng, NanWeihua, Li Dashuai, Zhang Chuanbo, Lu Chunzhe, Qi Haishan, Lu Wenyu*. A modularengineering strategy for high-level production of protopanaxadiol from ethanolby Saccharomyces cerevisiae [J]. AIChE Journal, 2019, 65(3): 866-874.
2. Sun Jie, Zhang Chuanbo, NanWeihua, Li Dashuai, Ke Di, Lu Wenyu*. Glycerol improves heterologousbiosynthesis of betulinic acid in engineered Yarrowia lipolytica[J]. ChemicalEngineering Science, 2019, 196: 82-90.
3. Liu S, Diao N, Wang Z, et al.Modular engineering of the flavin pathway in Escherichia coli for improvedflavin mononucleotide and flavin adenine dinucleotide production[J]. Journal ofagricultural and food chemistry, 2019. 67(23): 6532-6540.
4. Zhao Fanglong, Zhang Chuanbo,Nan Weihua, Lu Wenyu*. An integrated bioprocess for fermentative production ofprotopanaxadiol by recycling ethanol waste during down-stream extractionprocess[J]. Journal of Cleaner Production, 2019, 234: 1-8.
5. Liu Jingjing, Zhang Chuanbo, LuWenyu*. Biosynthesis of long-chain ω-hydroxy fatty acids by engineeredSaccharomyces cerevisiae[J]. Journal of agricultural and food chemistry, 2019,67(16): 4545-4552
6. Zhang Chuanbo, Ju Haiyan, LuChun-Zhe, Zhao Fanglong, Liu Jingjing, Guo Xiaoyan, Wu Yufen, Zhao Guang-Rong,Lu Wenyu*. High-titer production of 13-R manoyl oxide in metabolicallyengineered Saccharomyces cerevisiae [J]. Microbial cell factories, 2019, 18(1):73-81
7. Jia Dan, Xu Shuo, Sun Jie,Zhang Chuanbo, Li Dashuai, Lu Wenyu*. Yarrowia lipolytica construction forheterologous synthesis of α-santalene and fermentation optimization[J]. AppliedMicrobiology and Biotechnology, 2019, 103(8): 3511-3520.
8. Li Dashuai, Wu Yufen, ZhangChuanbo, Sun Jie, Zhou Zhijiang, Lu Wenyu*. Production of triterpeneginsenoside compound K in the nonconventional yeast Yarrowia lipolytica [J].Journal of Agricultural and Food Chemistry, 2019, 67(9): 2581–2588.
9. Wu Yufen, Xu Shuo, Gao Xiao, LiMan, Li Dashuai, Lu Wenyu*. Enhanced protopanaxadiol production from xylose byengineered Yarrowia lipolytica [J]. Microbial Cell Factories, 2019, 18(1):83-94.
10. Guo Xiaoyan, Liu Jingjing, ZhangChuanbo, Zhao Fanglong, Lu Wenyu*. Stepwise increase in the production of13R-manoyl oxide through metabolic engineering of Saccharomyces cerevisiae [J].Biochemical Engineering Journal, 2019, 144: 73-80.
11. Lu Wenyu, Zhu Baozhong, JiaXiaoqiang*; Development and Optimization of Oil Spill Dispersant for HighViscosity Oil Spill; Transactions of Tianjin University; 52(1); 2019; 26-32.
12. Tan Jinxiu, Yang Xiaona, LuWenyu*. Research of 1, 3-dihydroxyacetone production by overexpressing glyceroltransporter and glycerol dehydrogenase[J]. Transactions of Tianjin University,2019, 1-10.
2018
13. Zhang Chuanbo, Liu Jingjing,Zhao Fanglong, Lu Chunzhe, Zhao Guang-Rong Lu Wenyu*. Production ofsesquiterpenoid zerumbone from metabolic engineered Saccharomycescerevisiae[J]. Metabolic Engineering, 2018, 49: 28-35.
14. Lu Chun-Zhe, Zhang Chuanbo,Zhao Fanglong, Li Dashuai, Lu Wenyu*. Biosynthesis of ursolic acid andoleanolic acid in Saccharomyces cerevisiae [J]. AIChE Journal, 2018, 64(11):3794-3802.
15. Gao Xiao, Caiyin Qinggele, ZhaoFanglong, Yufen Wu, Lu Wenyu*. Engineering Saccharomyces cerevisiae forenhanced production of protopanaxadiol with cofermentation of glucose andxylose[J]. Journal of Agricultural and Food Chemistry, 2018. 66(45):12009–12016.
16. Liu Ting, Zhang Chuanbo, LuWenyu*. Heterologous production of levopimaric acid in Saccharomyces cerevisiae[J]. Microbial cell factories, 2018, 17 (1): 114-123.
17. Guo Xiaoyan, Sun Jie, LiDashuai, Lu Wenyu*. Heterologous biosynthesis of (+)-nootkatone inunconventional yeast Yarrowia lipolytica[J]. Biochemical Engineering Journal,2018, 137: 125-131.
18. Zhang Yaguang, Jia Dan, SunWanqi, Yang Xue, Zhang Chuanbo, Zhao Fanglong, Lu Wenyu*. Semicontinuoussophorolipid fermentation using a novel bioreactor with dual ventilation pipesand dual sieve‐plates coupled with a novelseparation system[J]. Microbial biotechnology, 2018, 11(3): 455-464.
19. Ke Di, Caiyin Qinggele, ZhaoFanglong, Liu Ting, Lu Wenyu*. Heterologous biosynthesis of triterpenoidambrein in engineered Escherichia coli[J]. Biotechnology letters, 2018, 40(2):399-404.
20. Zhang Chuanbo, Ke Di, DuanYuejiao, Lu Wenyu*. The combinatorial biosynthesis of “unnatural” products withpolyketides[J]. Transactions of Tianjin University, 2018, 24(6): 501-512.
21. Liu Zhen, Wang Yiting, JiaXiaoqiang, Lu Wenyu*. Isolation of secondary metabolites with antimicrobialactivities from Bacillus amyloliquefaciens LWYZ003[J]. Transactions of TianjinUniversity, 2018, 25 (1): 1-7.
2017
22. ZhaoFanglong, Du Yanhui, Bai Peng, Liu Jingjing, Lu Wenyu*, Yuan Yingjin. Enhancing Saccharomyces cerevisiae reactive oxygen species and ethanol stresstolerance for high-levelproduction of protopanoxadiol[J].Bioresource technology, 2017, 227: 308-316.
23. LuChunzhe, Yin Jin, Zhang Chuanbo, Lu Wenyu*. Fed-Batch Fermentation for Spinosad Production in an ImprovedReactor[J]. Transactions of TianjinUniversity, 2017, 23(6): 530-537.
24. TingLiu,Xiangmei Zhang,Fanglong Zhao, Lu Wenyu*.Molecular simulation and catalyticactive sites identification of dammarenediol-Ⅱsynthase[J].Journal of Beijing Institute of Technology, 2017, 26(04):563-570.
25. LuChunzhe, Yin Jin, Zhao Fanglong, Li Feng Lu Wenyu*. Metabolomicsanalysis of the effect of dissolved oxygen on spinosad production by Saccharopolyspora spinosa[J].Antonie van Leeuwenhoek, 2017, 110 (5): 677-685.
2016
26. ZhaoFanglong, Bai Peng, Liu Ting, Li Dashuai, Zhang xiangmei, Lu Wenyu*, YuanYingjin.. Optimization of a cytochrome P450 oxidation system for enhancingprotopanaxadiol production in Saccharomyces cerevisiae[J]. Biotechnology andbioengineering, 2016, 113(8): 1787-1795.
27. LiDashuai, Zhang Qiang, Zhou Zhijiang, Zhao Fanglong Lu Wenyu*. Heterologousbiosynthesis of triterpenoid dammarenediol-II in engineered Escherichia coli[J].Biotechnology letters, 2016, 38(4): 603-609.
2015
28. LinFujian, Guo Xiaoyan, Lu Wenyu*. Efficientbiotransformation of ginsenoside Rb1 to Rd by isolated Aspergillus versicolor,excreting β-glucosidase in the spore production phase of solid culture[J].Antonie van Leeuwenhoek, 2015, 108(5): 1117-1127.
29. ZhangChuanbo, Xue Chaoyou, Shen Yueqi, Lu Wenyu*. Selectionof reference genes in Saccharopolyspora spinosa for real-time PCR[J].Transactions of Tianjin University, 2015, 21(5): 461-467.
30. ZhaoFanglong, Zhang Chuanbo, Yin Jin, Shen Yueqi Lu Wenyu*. Coupling of spinosadfermentation and separation process via two-step macroporous resin adsorptionmethod[J]. Applied biochemistry and biotechnology, 2015, 176(8):2144-2156.
31. HuCheng, Lu Wenyu*. Insight into yeast: a study model of lipid metabolism andterpenoid biosynthesis[J]. Biotechnology and applied biochemistry, 2015, 62(3):323-328.
2014
32. WuXinsen, Wang Xiaoyang, Lu Wenyu*. Genome-scale reconstruction of a metabolicnetwork for Gluconobacter oxydans 621H[J]. Biosystems, 2014, 117: 10-14.
33. WangXiaoyang, Zhang Chuanbo, Wang Meiling, Lu Wenyu*. Genome-scalemetabolic network reconstruction of Saccharopolysporaspinosa for Spinosad Production improvement[J]. Microbial cellfactories, 2014, 13(1): 41-47.
34. ZhangXiangmei, Xue Chaoyou, Zhao Fanglong, Li Dashuai, Yin Jing, Zhang Chuanbo,Caiyin Qinggele, Lu Wenyu*. Suitable extracellular oxidoreduction potential inhibit rexregulation and effect central carbon and energy metabolism in Saccharopolyspora spinosa[J].Microbial cell factories, 2014, 13(1): 98-108.
2013
35. XueChaoyou, Duan Yuejiao, Zhao Fanglong, Lu Wenyu*.Stepwise increase of spinosad production in Saccharopolysporaspinosa by metabolic engineering[J]. Biochemical engineering journal, 2013,72: 90-95.
36. ZhaoFanglong, Xue Chaoyou, Wang Meiling, Wang Xiaoyang Lu Wenyu*. Acomparative metabolomics analysis of Saccharopolysporaspinosa WT, WH124, and LU104 revealed metabolic mechanismscorrelated with increases in spinosad yield[J]. Bioscience, biotechnology, andbiochemistry, 2013, 77(8): 1661-1668.
37. XueChaoyou, Zhang Xiangmei, Yu Zhirui, Zhao Fanglong, Wang Meiling, Lu Wenyu*. Up-regulatedspinosad pathway coupling with the increased concentration of acetyl-CoA andmalonyl-CoA contributed to the increase of spinosad in the presenceof exogenous fatty acid[J]. Biochemical engineering journal, 2013, 81: 47-53.
2012
38. ZhuLingqing, Yang Xue, Xue Chaoyou, Chen Yu, Qu Liang Lu Wenyu*. Enhanced rhamnolipids production by Pseudomonas aeruginosa based on a pHstage-controlled fed-batch fermentation process[J]. Bioresourcetechnology, 2012, 117: 208-213.
39.Yang Xue, Zhu Lingqing, Xue Chaoyou,Chen Yu, Qu Liang Lu Wenyu*. Recovery of purified lactonic sophorolipids byspontaneous crystallization during the fermentation of sugarcane molasses with Candida albicans O-13-1[J].Enzyme and microbial technology, 2012, 51(6): 348-353.
40.Wu Xinen, Xia Zhendong, Yang Xue,Xue Chaoyou Lu Wenyu*. Molecular simulation of pyrroloquinolinequinine-dependent glycerol dehydrogenase in Gluconobacter oxydans[J].Molecular Simulation, 2012, 38(12): 1010-1014.
Before 2011
41. Lu Wenyu，Fan Jinghua，Wen Jianping，Xia Zhendong，Caiyin Qinggele，Kinetic Analysis and Modeling of Daptomycin Batch Fermentation by Streptomyces roseosporus，AppliedBiochemistry and Biotechnology，2011，163（4）：453-462.
42. Lu Wenyu，Wen Jianping，Jia Xiaoqiang，Sun Bing，Chen Yu，Liu Minhui. Effectof He-Ne laser irradiation on hydrogen production by Enterobacter aerogenes，International Journal ofHydrogen Energy，2008，33（1）：34-42.
43. Lu Wenyu，Wen Jianping，Chen Yu，Sun Bing，Jia Xiaoqiang，Liu Minghui，Caiyin Qinggele，Synergistic effect of Candida maltosa HY-35 and Enterobacter aerogenes W-23on hydrogen production，International Journal ofHydrogen Energy，2007，32（8）：1059-1066.
授权专利：
1. 卢文玉，尹静，张传波，生物反应器，专利号：ZL3.X
2. 卢文玉，王晓阳，张传波，刺糖多孢菌基因组尺度代谢网络模型及构建方法及应用，专利号：ZL8.0
3. 卢文玉，王美玲，赵方龙，一种多杀菌素的发酵方法，专利号：ZL6.1
4. 卢文玉，薛朝友，张香梅，能提高多杀菌素产量的基因工程菌及构建方法及应用，专利号：ZL9.5
5. 卢文玉，赵方龙. 能提高达玛烯二醇转化效率的融合蛋白质及构建方法及应用, 专利号：ZL4.6
6. 卢文玉，赵方龙.能提高达玛烯二醇转化效率的融合蛋白质及构建方法，专利号：ZL4.3
7. 卢文玉，赵方龙.一种能提高达玛烯二醇转化效率的融合蛋白质及构建方法及应用, 专利号：ZL7.X
8. 卢文玉，李大帅，张强，赵方龙.合成达玛烯二醇的大肠杆菌基因工程菌株及构建方法，专利号：ZL0.X
9. 卢文玉，张亚光，杨雪. 一种槐糖脂发酵生物分离系统及方法，中国发明专利，专利号：ZL5.9
10. 卢文玉，林福建，郭校燕，一种转化人参皂苷Rb1生产Rd的曲霉及应用，专利号：ZL7x
编著教材：
参编《微生物工程技术原理》

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卢文玉现任职称/职务：副教授/博导（生物化工）/生化系副主任
通讯地址：天津大学北洋园校区54-226
电子邮箱：wenyulu@tju.edu.cn
办公电话：**
合作交流: 与中科院上海植生所、药物所、工生所、南开大学、中海油等单位开展广泛的交流合作。