张建华现任职称/职务：副教授
通讯地址：天津市海河教育园区天津大学化工学院50楼B447
电子邮箱：jhuazhang@tju.edu.cn
办公电话：**
研究方向: 高分子纳米功能材料；生物医用材料；活性聚合; 高性能防腐涂料；油田采收助剂
实验室链接

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张建华现任职称/职务：副教授
通讯地址：天津市海河教育园区天津大学化工学院50楼B447
电子邮箱：jhuazhang@tju.edu.cn
办公电话：**
研究方向: 高分子纳米功能材料；生物医用材料；活性聚合; 高性能防腐涂料；油田采收助剂
实验室链接

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张建华现任职称/职务：副教授
通讯地址：天津市海河教育园区天津大学化工学院50楼B447
电子邮箱：jhuazhang@tju.edu.cn
办公电话：**
讲授课程: 高分子材料合成与加工
实验室链接

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张建华现任职称/职务：副教授
通讯地址：天津市海河教育园区天津大学化工学院50楼B447
电子邮箱：jhuazhang@tju.edu.cn
办公电话：**
学术兼职: 中国医药生物技术协会外用制剂产业联盟常务理事；中国生物材料学会会员；
Journal of Materials Chemistry,Biomaterials, Journal of Controlled Release, Nanoscale, Biomacromolecules, ACSApplied Materials & Interfaces, EuropeanJournal of Pharmaceutics and Biopharmaceutics, Pharmaceutical Research, PolymerChemistry, Acta Biomaterialia等国际高水平期刊审稿人
实验室链接

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张建华现任职称/职务：副教授
通讯地址：天津市海河教育园区天津大学化工学院50楼B447
电子邮箱：jhuazhang@tju.edu.cn
办公电话：**
学术成就: 一直从事活性自由基聚合及利用活性聚合等技术制备功能性高分子材料的相关研究，在特定结构与性能的聚合物的合成、智能纳米给药载体的构建、功能性防腐涂料和高性能油田采收试剂的开发等方面已经取得一定的研究成果，已先后在Small, Journal of Materials Chemistry, Biomaterials,Journal of Controlled Release, Nanoscale, Biomacromolecules, ACSApplied Materials & Interfaces, EuropeanJournal of Pharmaceutics and Biopharmaceutics, Pharmaceutical Research, PolymerChemistry, Acta Biomaterialia等国内外主流的高分子、生物材料、纳米材料，药物控释等期刊上发表研究论文60多篇，相关研究成果已得到国内外同行专家的关注，论文SCI引用约500来次。 实验室链接

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张建华现任职称/职务：副教授
通讯地址：天津市海河教育园区天津大学化工学院50楼B447
电子邮箱：jhuazhang@tju.edu.cn
办公电话：**
科研项目: 1.国家自然科学基金面上项目，**，基于葡萄糖敏感的多孔微球/聚合物复合凝胶的胰岛素高效负载和控释, 2015/01-2018/12，85万元，在研，主持
2.国家自然科学基金面上项目，**，功能性纳米纤维复合膜及其在经皮给药系统中调控多药均衡释放的研究, 2012/01-2014/12，25万元，结题，主持
3.国家自然科学基金面上项目，**，聚集诱导荧光环糊精超分子体系的点击构筑及传感行为研究, 2016/01-2019/12， 65万元，在研，参加
4.国家自然科学基金面上项目，**，通过纳米递送系统的功能性组装协调siRNA的负载、输运与释放, 2013/01-2016/12，85万元，在研，参加
5.国家自然科学基金面上项目，**，高分子载体结构设计及其对艾滋病疫苗的黏膜免疫促进作用, 2008/01-2010/12，35万元，在研，参加
实验室链接

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张建华现任职称/职务：副教授
通讯地址：天津市海河教育园区天津大学化工学院50楼B447
电子邮箱：jhuazhang@tju.edu.cn
办公电话：**
论著专利:

2016年
（1） RuiweiGuo, Xing Chen, Xiaolei Zhu, Anjie Dong, JianhuaZhang*, A facile strategy to fabricate covalently linked raspberry-likenanocomposites with pH and thermo tunable structures, RSC Advance , 2016,6, 40991-41001.
（2） RuiweiGuo, Qing Zhong, Anjie Dong, JianhuaZhang*, Facile Fabrication of Silica Nanocapsules with Well-DefinedMesoporous Shell via a Poly(N,N-dimethylaminoethylmethacrylate)-Assisted Self-Template Etching Process, Journal of Nanoscience and Nanotechnology, 2016, 16, 9708-9715.
（3） Shuxin Xu,Li Yin, Yuzhang Xiang, Hongzhang Deng, Liandong Deng, Hongxia Fan, Hua Tang, Jianhua Zhang, Anjie Dong,Supramolecular Hydrogel from Nanoparticles and Cyclodextrins for Local andSustained Nanoparticle Delivery, MacromolecularBioscience, 2016, 16(8) 1188–1199.
(4) Shuxin Xu, HongxiaFan, Li Yin, Jianhua Zhang, Anjie Dong,Liandong Deng, Hua Tang, Thermosensitive hydrogel system assembled byPTX-loaded copolymer nanoparticles for sustained intraperitoneal chemotherapyof peritoneal carcinomatosis, EuropeanJournal of Pharmaceutics and Biopharmaceutics, 2016, 104, 251-259.

2015年
（1） Fuli Zhao, Dan Yao, Ruiwei Guo, Liandong Deng, Anjie Dong, and Jianhua Zhang*. Composites of Polymer Hydrogels and Nanoparticulate Systems forBiomedical and Pharmaceutical Applications. Nanomaterials 2015, 5, 2054-2130. (Feature paper)
（2） Liandong Deng, Hongxu Dong, Anjie Dong, Jianhua Zhang*, A strategy for oral chemotherapy via dualpH-sensitive polyelectrolyte complex nanoparticles to achieve gastricsurvivability, intestinal permeability, hemodynamic stability and intracellularactivity, European Journal ofPharmaceutics and Biopharmaceutics 2015, 97, 107-117.
（3） Jianhua Zhang, Weiwei Gao, Ronnie H. Fang, Anjie Dong, Liangfang Zhang，Synthesis ofnanogels via cell membrane-templated polymerization, Small, 2015, 11, 34, 4309-4313.
（4） Pingsheng Huang, Weiwei Wang,Junhui Zhou, Fuli Zhao, Yumin Zhang, Jinjian Liu, Jianfeng Liu, Anjie Dong, DelingKong*, and Jianhua Zhang*, Amphiphilic polyelectrolyte/prodrugnanoparticles constructed by synergetic electrostatic and hydrophobicinteractions with cooperative pH-sensitivity for controlled doxorubicin delivery, ACS Applied Materials & Interfaces, 2015, 7(11), 6340–6350
（5） Ruiwei Guo, Pengbo Mei, Qing Zhong, Yuan Yao, Qian Su and Jianhua Zhang*, Well-defined triblockcopolymers with a photolabile middle block of poly(phenyl vinyl ketone): facilesynthesis, chain-scission mechanism and controllable photocleavability, RSC Advances, 2015, 5, 31365– 31374.

2014年
（1）Junqiang Zhao, Jinjian Liu, Shangcong Han, Hongzhang Deng, Liandong Deng, Jianfeng Liu, Aimin Meng, Anjie Dong, Jianhua Zhang*, Acid-induced disassemblable nanoparticles based on cyclic benzylidene acetal-functionalized graft copolymer via sequential RAFT and ATRP polymerization, Polymer Chemistry, 2014, 5, 1852-1856.
（2）Yongli Shi, Yue Li, Jianming Wu, Weiguo Wang, Anjie Dong, Jianhua Zhang*, A novel transdermal drug delivery system based on self-adhesive Janus nanofibrous film with high breathability and monodirectional water-penetration, Journal of Biomaterials Science: Polymer Edition, 2014, 25(7),713-728.
（3）Yunlong Guo, Jianhua Zhang, Peile Xie, Xiang Gao, Yingwu Luo, Tailor-made compositional gradient copolymer by many-shot RAFT emulsion polymerization method, Polym. Chem., 2014, 5, 3363-3371.
（4）Weiwei Wang, Liandong Deng, Pingsheng Huang, Shuxin Xu, Xu Li, Nan Lv, Lei Wang, Renjie Hu, Jianhua Zhang, Anjie Dong, Toxicity and in vivo biological effect of the nanoparticular self-supported hydrogel of a thermosensitive copolymer for non-invasive drug delivery, Journal of Biomedical Materials Research Part A, 2014, 102(1): 17-29.
（5）Shangcong Han, Haiying Wan, Daoshu Lin, Shutao Guo, Hongxu Dong, Jianhua Zhang, Liandong Deng, Ruming Liu, Hua Tang, Anjie Dong, Contribution of hydrophobic/hydrophilic modification on cationic chains of poly(epsilon-caprolactone)-graft-poly(dimethylamino ethylmethacrylate) amphiphilic co-polymer in gene delivery, Acta Biomaterialia, 2014, 10(2), 670-679.
2013年：
（1）Junqiang Zhao, Haiyang Wang, Jinjian Liu, Liandong Deng, Jianfeng Liu, Anjie Dong, Jianhua Zhang*, Comb-like amphiphilic copolymers bearing acetal-functionalized backbone with the ability of acid-triggered hydrophobic to hydrophilic transition as nanocarriers for intracellular release of curcumin, Biomacromolecules, 2013, 14 (11), 3973-3984 (二区, IF=5.479).
（2）Jianhua Zhang, Xiaona Lin, Jinjian Liu, Junqiang Zhao, Hongxu Dong, Liandong Deng, Jianfeng Liu and Anjie Dong, Sequential thermo-induced self-gelation and acid-triggered self-release process of drug-conjugated nanoparticles: A strategy for sustained and controlled drug delivery to tumor. Journal of Materials Chemistry B, 2013, 1 (36), 4667-4677. (一区, IF= 6.101) EI: 20**5
（3）Ruiwei Guo, Yifan Liu, Yao Zhang, Anjie Dong, Jianhua Zhang*, Surface modification by self-assembled coating with amphiphilic comb-shaped block copolymers: A solution to the trade-off among solubility, adsorption and coating stability, Macromolecular Research, 2013, 21(10), 1127-1137 (二区, IF=1.643) EI: 20**3
（4）Yongli Shi, Zhen Wei, Hui Zhao, Ting Liu, Anjie Dong, Jianhua Zhang?, Electrospinning of ibuprofen-loaded composite nanofibers for improving the performances of transdermal patches, Journal of Nanoscience and Nanotechnology, 2013, 13, 3855-3863 (三区, IF=1.563) EI: 20**1
（5）Yongli Shi, Suxin Xu, Anjie Dong, Jianhua Zhang*, Design and in vitro evaluation of transdermal patches based on ibuprofen-loaded electrospun fiber mats, Journal of Materials Science: Materials in Medicine, 2013 24:333-341. (二区, IF=2.316) EI: 20**8
（6）Yongli Shi, Jianhua Zhang, Suxin Xu, Anjie Dong. Electrospinning of artemisinin-loaded core-shell fibers for inhibiting drug re-crystallization. Journal of Biomaterials Science: Polymer Edition, 2013, 24(5):551-564 ( 二区，IF=1.842 )
（7）Longlong Chang, Jinjian Liu, Jianhua Zhang, Liandong Deng and Anjie Dong, pH-sensitive nanoparticles prepared from amphiphilic and biodegradable methoxy poly(ethylene glycol)-block-(polycaprolactone-graft-poly(methacrylic acid)) for oral drug delivery, Polymer Chemistry, 2013, 4, 1430-1438. (二区, IF=5.321) EI: 20**6
（8）Weiwei Wang, Liandong Deng, Shuxin Xu, Xiumei Zhao, Nan Lv, Guixian Zhang, Na Gu, Renjie Hu, Jianhua Zhang, Jinjian Liu, Anjie Dong, A reconstituted “two into one” thermosensitive hydrogel system assembled by drug-loaded amphiphilic copolymer nanoparticles for the local delivery of paclitaxel, Journal of Materials Chemistry B, 2013, 1, 552-563. (一区, IF=5.968) EI：20**1
（9）Zhao, Junqiang, Liu, Jinjian, Xu, Shuxin, Zhou, Junhui, Han, Shangcong, Deng, Liandong, Zhang, Jianhua, Liu, Jianfeng, Meng, Aimin, Dong, Anjie, Graft copolymer nanoparticles with ph and reduction dual-induced disassemblable property for enhanced intracellular curcumin release, ACS Applied Materials & Interfaces, 2013, 5(24): 13216-13226.
（10）Chang, Longlong, Wang, Weiwei; Huang, Pingsheng; Lv, Zesheng; Hu, Fuqiang; Zhang, Jianhua; Kong, Deling; Deng, Liandong; Dong, Anjie , Photo-crosslinked poly(ethylene glycol)-b-poly(Ε-caprolactone) nanoparticles for controllable paclitaxel release, Journal of Biomaterials Science, Polymer Edition, 2013, 24: 1900-1921.
（11）Junqiang Zhao, Jinjian Liu, Shuxin Xu, Junhui Zhou, Shangcong Han, Liandong Deng, Jianhua Zhang, Jianfeng Liu, Aimin Meng, Anjie Dong, Graft Copolymer Nanoparticles with pH and Reduction Dual-Induced Disassemblable Property for Enhanced Intracellular Curcumin Release, ACS Applied Materials & Interfaces, 2013, 5(24), 13216-13226.
（12）郭睿威 ，崔福员，赵书英，张建华，两亲梳型嵌段共聚物的合成及对PAN膜的改性，天津大学学报, 2013, 10: 945-950.
Guo Ruiwei, Cui Fuyuan, Zhao Shuying, Zhang Jianhua. Synthesis of Amphiphilic Comb-Shape Block Copolymers and Its Application in Modification of Polyacrylonitrile Film, Journal of Tianjin University, 2013, (10): 945-950.
2012年：
（1）Longlong Chang, Liandong Deng, Weiwei Wang, Zesheng Lv, Fuqiang Hu, Anjie Dong, Jianhua Zhang*, Poly(ethyleneglycol)-b- poly(ε-caprolactone-co-γ-hydroxyl-ε- caprolactone) bearing pendant hydroxyl groups as nanocarriers for doxorubicin delivery, Biomacromolecules, 2012,13, 3301-3310 (二区, IF=5.479). EI:838
（2）Ruiwei Guo, Zhipeng Shi, Xingxing Wang, Anjie Dong, Jianhua Zhang*, Separation and quantification of dead species in styrene RAFT polymerization
by gradient polymer elution chromatography, Polymer Chemistry, 2012, 3, 1314- 1321 (二区, IF=5.321). EI: 567
（3）Ruiwei Guo, Xingxing Wang, Chungang Guo, Anjie Dong, Jianhua Zhang*, Facile and efficient synthesis of fluorescence-labelled raft agents and their application in the preparation of α-,ω- and α,ω-end-fluorescence-labelled polymers, Macromolecular Chemistry and Physics, 2012, 213, 1274-1284 (三区, IF=2.361).EI: 114
（4）Bin Liu, Liandong Deng, Chungang Guo, Ruiwei Guo, Anjie Dong, Jianhua Zhang*, Facile prepared bis(carbazyl thiocarbonyl) disulfide as chain transfer agent for RAFT polymerization of methyl methacrylate, Journal of Applied Polymer Science, 2012, 126(2), 740-748 (四区, IF=1.289). EI: 841
（5）Weiwei Wang, Liandong Deng, Shasha Liu, Xu Li, Xiumei Zhao, Renjie Hu, Jianhua Zhang, Haijie Han, Anjie Dong, Adjustable degradation and drug release of a thermosensitive hydrogel based on a pendant cyclic ether modified poly(e-caprolactone) and poly(ethylene glycol)co-polymer, Acta Biomaterialia, 2012, 8:3963–3973 (一区，IF=4.824)
（6）董岸杰, 张睿, 张建华*,邓联东, 共聚物压敏胶的链段结构对其力学性能和药物释放的调控, 天津大学学报，2012, 45(11)：1013-1019
Dong An-jie, Zhang Rui, Zhang Jian-hua, Deng Lian-dong. Effect of Segment Structure on Mechanical Properties and Drug Release Behavior of Copolymer Pressure Sensitive Adhesives, Journal of Tianjin University, 2012, (11): 1013-1019.
（7）李宁, 丁建明, 董岸杰, 张建华, 邓联东，二醋酸纤维素接枝聚甲基丙烯酸甲酯的合成与表征，化学工业与工程, 2012，04，pp 11-14,
2011年：
（1）Ruiwei Guo, Xiaoyan Du, Rui Zhang, Liandong Deng, Anjie Dong, Jianhua Zhang*, Bioadhesive film formed from a novel organic-inorganic hybrid gel for transdermal drug delivery system, European Journal of Pharmaceutics and Biopharmaceutics, 2011,79, 574–583; (二区, IF=4.369)
（2）张睿, 张建华*, 赵胡笳, 邓联东, 董岸杰, 经皮给药用酯化淀粉基压敏胶的制备与性能研究, 中国胶粘剂，2011, 20(11)：30-33
2010年：
（1）Jianhua Zhang, Liandong Deng, Hujia Zhao, Mei Liu, Hongjian Jin, Jingqing Li, Anjie Dong, Pressure sensitive adhesive properties of poly(N-vinyl pyrrolidone)/D,L-lactic acid oligomer/glycerol/water blends for TDDS, Journal of Biomaterials Science: Polymer Edition, 2010, 21,1–15 (二区, IF=1.842 ) EI: 434
（2）Jianhua Zhang, Mei Liu, Hongjian Jin, Liandong Deng, Jinfeng Xing, Anjie Dong, In vitro Enhancement of Lactate Esters on the Percutaneous Penetration of Drugs with Different Lipophilicity, AAPS PharmSciTech, 2010, 11(2): 894-903（四区，IF=1.211）
（3）Jianhua Zhang, Ruiwei Guo, Guicun Qi, Mei Liu, Anjie Dong, Synthesis and investigation of well-defined and fluorescence-labelled CPMMA by raft polymerization, Acta Polymerica Sinica, 2010, 6:691-698 (四区，IF= 0.481)
2009年：
（4）Jianhua Zhang, Zhipeng Liu, Hai Du, Yong Zeng, Liandong Deng, Jinfeng Xing, and Anjie Dong, A novel hydrophilic adhesive matrix with self-enhancement for drug percutaneous permeation through rat skin, Pharmaceutical Research, 2009, 26(6):1398-1406 (二区，IF= 4.45 ) 442IJ
（5）Jianhua Zhang, Ruiwei Guo, Li. Bin, Anjie Dong, Synthesis and application of RAFT agent para-Xylylene di(N-carbazylcarbodithioate), Chemical Journal of Chinese Universities, 2009, 30(8): 1668-1673 (四区，IF= 0.548)
2008年及以前：
（6）Jianhua Zhang, Anjie Dong, Tongyu Cao, Ruiwei Guo, Carbazyl RAFT agents synthesized by an improved aqueous phase method and their applications in RAFT polymerization, European Polymer Journal, 2008, 44(4): 1071-1080 (三区, IF= 2.51) EI: 245 297OI
（7）张建华,郭睿威，赵宗峰，董岸杰, N-咔唑基RAFT试剂在RAFT聚合中阻滞效应的研究,天津大学学报, 2008,41(7): 843-848. (EI核心)
（8）郭睿威, 张建华, 赵宗峰，戚桂村, N-咔唑二硫代甲酸异丙苯酯的合成及应用,天津大学学报,2007, 40(8):906-910. (EI核心，导师为第一作者)
（9）张建华, 邓联东, 董岸杰,高分子材料的结构与其在经皮给药系统中的作用, 中医外治杂志, 2007, 5: 3-6.
（10）郭睿威, 戚桂村,金启明,张建华,细乳液聚合研究进展,化工进展, 2005, 24(2):159-164.
实验室链接

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张建华现任职称/职务：副教授
通讯地址：天津市海河教育园区天津大学化工学院50楼B447
电子邮箱：jhuazhang@tju.edu.cn
办公电话：**
合作交流: 2014-2015，加州大学圣地亚哥分校，纳米工程系，访问****;
与中国医学科学院生物医学工程研究所、南开大学、天津药物研究院等的研究小组有着良好的协作关系和定期的学术交流;
与中国石油工程技术研究院等具有长期的合作关系；
实验室链接