王慧泉

生日：1985-11-26
政治面貌：党员邮箱: huiquan@tjpu.edu.cn
籍贯：河北张家口职务：博士、硕导、副教授、生科院副院长
天津市中青年骨干创新人才培养计划人选
教育及工作背景 EDUCATION AND WORK BACKGROUND
2017.01-2019.01天津大学仪器科学与技术博士后
2014.06-今天津工业大学生物医学工程专业系主任
2011.08-2013.08 Johns Hopkins University BME Department国家公派访问****
2008.09-2014.06 天津大学精密仪器与光电子工程学院生物医学工程博士
2004.09-2008.07 天津大学精密仪器与光电子工程学院生物医学工程学士
2005.09-2008.07 南开大学国际金融学（学士双学位）
研究方向 RESEARCH DIRECTION
可穿戴医疗设备、近红外光谱分析、数据挖掘、生物医学信号分析与处理、分子生物学（联合培养方向）
项目经历 PROJECT EXPERIENCE
2014.07-今天津市医学电子诊疗工程技术中心
可穿戴医疗设备研发、超光谱成像应用
2010.09-2013.08Laboratory of Biophotonics Imaging and Therapy, Johns Hopkins University, USA
分子荧光断层层析成像（FMT）、光学层析成像（OCT）：FMT系统搭建、散射模型的建立、仿真以及断层重建算法，实现对小鼠体内荧光物质浓度分布三维重建；SS-OCT系统设计。
2008.09-2010.08 生物医学信号分析与处理天津市重点实验室，天津大学
参与国家自然科学基金《血液成分无创检测的动态光谱理论与方法》的研究：检测方法的创新、检测仪器的设计、临床试验、数据挖掘分析等。
2008.09-2010.08 测量与控制工程国家重点实验室，天津大学
参与国家自然科学基金《基于高谱图的中医舌诊规范化》研究：舌诊采集设备的搭建和数据建模分析等。
基金项目
1.天津市科委重点项目11JCZDC17100 基于动态光谱的血液成分无创分析仪器20万2011-04至2014-03 第二名（结题）
2.国家自然科学基金** 血液成分无创检测的动态光谱理论与方法的研究28万2007-01至2009-12 参与（结题）
3.国家自然科学基金**基于高光谱的中医舌诊规范化31万2010-01至2012-12 参与（结题）
4.内蒙古自治区科技计划项目基于物联网技术的智能健康监控及现代医疗信息系统研发100万2016-2019年天津工业大学负责人
5.国家纳米科学中心中科院纳米生物效应与安全性重点实验室开放课题NSKF201602多光谱荧光分子断层成像方法研究2万2016-2017年负责人
6.中国博士后科学基金会61批面上多光谱信息融合的荧光分子断层成像方法研究5万2017-2019 负责人
7.天津市互联网跨界融合专项基于互联网+的心血管健康管理服务系统研发与应用50万2018-2021 第二负责人
8.家用正压通气呼吸治疗机关键技术及样机研发天津市企业科技特派员项目5万18JCTPJC59200 2018-2021
9.智能化闭环自动心肺复苏反馈辨识-优化协调-协同控制关键技术与装备研究天津市军民融合重点项目75万2018-2021 天津工业大学负责人
10.基于深度学习和多光谱融合的荧光分子断层成像肿瘤检测方法研究，6万，天津市自然科学基金2019-2021，负责人
11.基于磁、声刺激的脑力疲劳缓解关键技术及可穿戴设备研发，5万，天津市科技特派员项目，2019-2021，负责人
12 面向肝癌精准检测的多光谱荧光分子断层重建关键技术研究，22万，国家自然科学基金，2020-2022，负责**
13. 亚毫米尺寸阵列式微磁刺激装置设计及其对海马区Schaffer-CAI突触可塑性调控机理的研究，2019.1-2019.12，第二，16万
科研成果SCIENTIFIC RESEARCH RESULTS
1.李刚,王慧泉,赵喆,等.动态光谱数据质量评价标准.光谱学与光谱分析,2010, 30(10): 2802-2806. (SCI: 668KP)(EI: 545)
Li Gang, Wang Huiquan, Zhao Zhe, et al. The quality evaluation of the dynamic spectrum data. Spectroscopy and Spectral Analysis, 2010, 3(10): 2802-2806.
2.李刚,王慧泉,赵喆,等. 利用谐波分量提高预测精度. 光谱学与光谱分析,2010, 30(9): 2385-2389. (SCI: 648AA)(EI: 942)
Li Gang, Wang Huiquan, Zhao Zhe, et al.Increase the precision of the non-invasive blood components measurement based on DS method using Harmonic Waves. Spectroscopy and Spectral Analysis, 2010, 30(9):2385-2389.
3.Huiquan Wang, Gang Li, Zhe Zhao, et al.Dynamic spectrum and BP neural network for non-invasive hemoglobin measurement. Life System Modeling and Intelligent ComputingLecture Notes in Computer Science, 2010, Volume 6330, 67-74.(SCI：BUI52) (EI：368)
4.Huiquan Wang, Gang Li, Zhe Zhao, et al.Non-invasive measurement of hemoglobin based on dynamic spectrum method. Transactions of the Institute of Measurement and Control, 2011, 35(1). (SCI: 134AV) (EI: 20**4)
5.李刚,王慧泉,张昊,等. 无创血液成分检测全波段信号信噪比均衡.光谱学与光谱分析, 2012, 32(2): 486-490. (SCI:883BB)(EI:758)
Li Gang, Wang Huiquan, Zhang Hao, et al. The equalization of whole-band signal’s SNR in the blood components noninvasive measurement. Spectroscopy and Spectral Analysis, 2012,32(2): 486-490.
6.李刚,王慧泉,赵喆,等. 提高DS法无创血液成分检测信噪比的方法与分析.光谱学与光谱分析, 2012, 32(8): 2290-2294.(SCI:983NW) (EI:465)
Li Gang, Wang Huiquan, Zhao Zhe, et al. The analysis for improving the SNR of blood components noninvasive measurement with DS method. Spectroscopy and Spectral Analysis, 2012, 32(8): 2290-2294.
7.李刚,赵喆,刘蕊,王慧泉,等. 利用多光程长光谱法检测血液多种成分含量的研究. 光谱学与光谱分析, 2010, 30(9): 2381-2384. (SCI:648AA)(EI:941)
Li Gang, Zhao Zhe, Liu Rui, Wang Huiquan, et al. Research on the blood components detecting by multi-optical path length spectroscopy technique. Spectroscopy and Spectral Analysis, 2011, 30(9): 2381-2384.
8.李刚,赵喆,刘蕊,王慧泉,等. 尿微量白蛋白的多波段多光程光谱检测,分析化学. 2011, 39(4):588-591.(SCI:786ZE)
Li Gang, ZhaoZhe, LiuRui,Wang Huiquan, et al. Urinary albumin detected by multi-band multi-optical path length spectroscopy technique. Chinese Journal of Analytical Chemistry. 2011, 39(4): 588-591.
9.李刚,门剑龙,孙兆敏,王慧泉,等. 动态光谱用于人体血液中多种蛋白的无创测量. 天大学报,2011, 14(1): 90-94. (EI:369)
Li Gang, Men Jian-long, Sun Zhao-min, Wang Huiquan,et al. Non-invasive measurement of human blood protein concentration based on dynamic spectrum method. Transactions of Tianjin University, 2011, 14(1): 90-94.
10.李刚,门剑龙,孙兆敏,王慧泉,等. 小波变换提高动态光谱法血液成分无创检测的精度. 光谱学与光谱分析, 2011 , 31 (2): 469-472.(SCI:729XH)(EI:742)
Li Gang, Sun Zhaomin, Wang Huiquan, et al. Application of wavelet transform on improving detecting precision of the non-invasive blood components measurement based on dynamic spectrum method. Spectroscopy and Spectral Analysis, 2011, 31(2): 469-472.
11.林凌,吴晓爽,王慧泉,等. 过采样提高等效分辨率. 电子设计工程, 2011,18(8): 48-51.
Lin Ling, Wu Xiaoshuang, Wang Huiquan, et al. Digital front-end in the software defined instrument and the equivalent resolution of ADC. Electronic Design Engineering, 2011, 18(8): 48-51.
12.李刚,熊婵,王慧泉,等. 动态光谱的单拍提取. 光谱学与光谱分析,2011, 31(7):1857-1861 .(SCI: 790GD) (EI: 331)
Li Gang, Xiong Chan, Wang Huiquan, et al. Single-Trial Estimation of Dynamic Spectrum. Spectroscopy and spectral analysis. Spectroscopy and Spectral Analysis, 2011, 31(7): 1857-1861.
13.李刚,赵喆,刘蕊,王慧泉,等. 尿微量白蛋白的可见-近红外光谱检测. 光谱学光谱分析,2011, 31(9): 2412-2415. (SCI:819AH) (EI:201**)
Li Gang, ZhaoZhe, LiuRui, WangHuiquan, et al. Research on The Measurement of Urinary Albumin by Visible-near InfraredSpectroscopy. Spectroscopy and spectral analysis,2011,31(9):2412-2415.
14.Wenfei Liu, Guili Liu, Xiaofei Wang, YanfeiBao, Gang Li, Huiquan Wang.Non-invasive measurement study of human blood alcohol concentration based on NIR dynamic spectrum. Image Analysis and Signal Processing (IASP), 2011 International Conference on , pp.492-495, Oct. 2011. (EI：760)
15.索永宽,李刚,王慧泉,等.基于动态光谱法的人体血液胆固醇含量无创检测. 光谱学光谱分析,2012, 32(1): 188-191. (SCI:873RI)(EI:657)
SuoYongkuan, Li Gang, WangHuiquan, et al. Non-Invasive Measurement of Human Blood Cholesterol Concentration Based on Dynamic Spectrum Method. Spectroscopy and Spectral Analysis,2012, 32(1): 188-191.
16.李刚,赵喆,王慧泉,等. 复杂液体光谱法分析的浓度分辨率及浓度分布影响. 光谱学光谱分析,2012,32(4): 1077-1080. (SCI:921AI)(EI:827)
Li Gang, ZhaoZhe, WangHuiquan, et al. The concentration resolutionof complex liquid spectrometry analysis and the effect of concentration distribution Spectroscopy and Spectral Analysis,2012,32(4) : 1077-1080.
17.李刚,赵喆,王慧泉,等. 浓度分布对光谱法检测成分含量精度的影响. 光谱学光谱分析,2012,32(7): 1905-1908. (SCI:987PN)(EI:552)
Li Gang, ZhaoZhe, WangHuiquan, et al. Effect of different distribution of components concentration on the accuracy of quantitative spectral analysis. Spectroscopy and Spectral Analysis,2012, 32(7): 1905-1908.
18.李刚,赵喆,王慧泉,等. 光谱仪器信噪比与建模波长数对光谱分析精度的影响. 光谱学光谱分析,2012,32(8): 2286-2289. (SCI: 983NW)(EI: 464)
Li Gang, ZhaoZhe, WangHuiquan, et al. The effects of signal to noiseratio of instrument and number of wavelengthsto the accuracy ofspectral analysis. Spectroscopy and Spectral Analysis,2012, 32(8): 2286-2289.
19.李刚,周梅,王慧泉,等. 动态光谱提取方法的对比研究. 光谱学与光谱分析,2012, 32(5): 1324-1328. (SCI:940NK)(EI:928)
Li Gang, Zhou Mei, Wang Huiquan, et al. Contrastive study on dynamic spectrum extraction method. Spectroscopy and Spectral Analysis, 2012, 32(5): 1324-1328.
20.Gao F, Edden RA, Li M, Puts NA, Wang G, Liu C, Zhao B, Wang H, Bai X, Zhao C, Wang X, Barker PB.Edited magnetic resonance spectroscopy detects an age-related decline in brain GABA levels. Neuroimage, 2013, 78C:75-82. ( IF= 5.895) (SCI: 165MV)
21.CuiB., Li P., Xu L., Peng Z., Zhao Y., Wang H., et al. Fecal microbiota transplantation is an effective rescue therapy for refractory inflammatory bowel disease. Pediatric Allergy Principles & Practice, 2015,2(1), 41-53. (SCI,EI)
22.Cui B., Li P., Xu L., Zhao Y., Wang H., Peng Z., et al. Step-up fecal microbiota transplantation strategy: a pilot study for steroid-dependent ulcerative colitis. Journal of Translational Medicine, 2015,13(1), 298. (SCI,EI)
23.Zheng B., Gong X., Wang H., Wang S., Wang H., Li W., et al. A nir-remote controlled upconverting nanoparticle: an improved tool for living cell dye-labeling. Nanotechnology, 2015,26(42), 425102. (SCI:003, 二区, IF:3.404)(EI:20**0)
24.Yan L., Wang H., Zhang A., Zhao C., Chen Y., & Li X. Bright and stable near-infrared Pluronic-silica nanoparticles as contrast agents for in vivo optical imaging. Journal of Materials Chemistry B, 2016,4(33):5560-5566. (SCI:007, 一区, IF: 4.776) (EI:20**5)
25.Jinhai Wang, Dongyuan Liu, Yanjun Zhang, Wang Huiquan*, et al. The study on increasing the equivalent SNR in the certain DOI by adjusting the SD separation in near-infrared brain imaging . International Symposium on Optoelectronic Technology and Application 2016:101572P. (SCI:095) (EI:20**0)
26.Image Reconstruction In Respiratory Monitoring Based on the Anatomical Information for Magnetic Detection Electrical Impedance Tomography.2016,13^thIEEEInternationalConferenceonSignalProcessing(SCI,EI)
27.王慧泉, 尹剑利, 李光旭,冯彦博, 王金海, & 陈瑞娟. 磁探测电阻抗成像呼吸监测仿真研究. 生物医学工程学杂志, 2017(1):27-33. (EI:20**9)
Huiquan Wang,Jianli Yin,Guangxu Li,YanboFeng.Image Reconstruction In Respiratory Monitoring Based on the Anatomical Information for Magnetic Detection Electrical Impedance Tomography. 2017, 33(1):27:33. (EI:20**9)
28.Huiquan Wang, Pengfei Hu, Yu Zheng, Zhe Zhao, Bin Zheng, Jin Chang, Hanjie Wang*, Jinhai Wang*, Construction of ICG encapsulated W18O49@MSN as a fluorescence carrier for real-time tracked photothermal therapy, Materials Science and Engineering: C, 2017, 80(1): 102~109(SCI: 013, 一区, IF:5.08)
29.Huiquan Wang, LinaRen, Zhe Zhao*, Jinhai Wang*, Hongli Chen, The study on fast localization method of anomaly block in brain based on differential optical density, Proc. SPIE 10484, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVI, San Francisco, California, 2018.1.30-2018.2.4.(EI:20**5)
30.Huiquan Wang, Haojie Zhu, Zhe Zhao*, Yanfeng Zhao, Jinhai Wang*, The Increasing of Discrimination Accuracy of Waxed Apples Based on Hyperspectral Imaging Optimized by Spectral Correlation Analysis, Artificial Intelligence and Robotics, 2017.10.4- 2017.10.5.(EI)
31.Huiquan Wang, Yanbo Feng, Jinhai Wang, Haofeng Qi, Zhe Zhao*, Ruijuan Chen*, The Research on the Lung Tumor Imaging Based on the Electrical Impedance Tomography, Artificial Intelligence and Robotics, 2017.10.5.(EI)
32.王金海, 刘东远, 王慧泉*, 张彦军, 孙秋明, 马军. 多通道差分吸光度用于颅内血肿快速检测. 光谱学与光谱分析, 2018, 38(10): 3205-3209.(SCI: 037, 四区, IF: 0.326)
WANG Jin-hai, LIU Dong-yuan, WANG Hui-quan, ZHANG Yan-jun, SUN Qiu-ming, MA Jun. Application of Multi-Channel Differential Optical Density on the Fast Determination of the Intracranial Hematomas Degree. Spectroscopy and Spectral Analysis，2018，38(10): 3205-3209. (EI:20**1)
33.张彦军, 孙秋明, 王慧泉, 赵喆, 孙景工, 马军, 刘东远.VIP分析简化近红外光硬膜血肿检测的研究.光谱学与光谱分析, 2018, 38(6):1691-1695.(SCI:007, 四区, IF:0.326) (EI:20**1)
Yanjun Zhang, Qiuming Sun, Huiquan Wang, Zhe Zhao, et al. VIP analysis to simplify the NIR detection study of the dural hematoma. Spectroscopy and Spectral Analysis, 2018, 38(6):1691-1695.
34.Sun Q., Zhang Y., Ma J., Tian F., Wang H., & Liu D, et al. Detector location selection based on vip analysis in near-infrared detection of dural hematoma.Saudi J Biol Sci,2018,25(3), 452-456.(SCI:008, 一区, IF:3.138)
35.王慧泉, 任丽娜, 赵喆, 王金海*, 基于差分光密度差异的组织内异质体的快速定位方法, 光谱学光谱分析,2018,38(11):3362-3367. (SCI:007, 四区, IF:0.326) (EI:20**4)
Huiquan Wang, LinaRen, Zhe Zhao, Jinhai Wang*, The study of fast localization method of anomaly block in tissue based on differential optical density, Spectroscopy and Spectral Analysis , 2018, 38(11) :3362-3367.
36.Huiquan Wang, LinaRen, Zhe Zhao, Jinhai Wang*, Hongli Chen. Fast Localization Method of Anomaly in Tissue Based on Differential Optical Density. Biomedical Optical Express,2018,9(5):2028-2026(SCI:001, 二区, IF:3.482) (EI:20**4)
37.Huiquan Wang, Haojie Zhu, Zhe Zhao*, Yanfeng Zhao, Jinhai Wang. The study on increasing the identification accuracy of waxed apples by hyperspectral imaging technology, Multimedia Tools and Applications, 2018, 70(20) :27505-27516. (SCI:057, 三区, IF:1.541) (EI:20**0)
38.Huiquan Wang, Feng Xing, Boya Shi, Wenxuan Liang, Yongping Chen, Jinhai Wang, Xingde Li.Signal-to-noise ratio analysis and improvement for fluorescence tomography imaging. Review of Scientific Instruments, 89(9),2018(SCI:028, 三区, IF:1.428) (EI:20**8)
39.Huiquan Wang, Wang Hui, Zhe Zhao*, Jinghong Miao*, Jinhai Wang.. The influence of spectral characteristics on the accuracy of concentration quantitatively analysis by near infrared spectroscopy,Infrared Physics &Technology,2018,94:96-101.(SCI:015, 二区, IF:1.851)(EI:20**8)
Huiquan, W. , Hui, W. , Zhe, Z. , Jinghong, M. , & Jinhai, W. . (2018). The influence of spectral characteristics on the accuracy of concentration quantitatively analysis by near infrared spectroscopy. Infrared Physics & Technology, S**04456-.
40.Yuyu Wang, Gang Li, Huiquan Wang, Mei Zhou & Ling Lin. Dynamic Spectrum for noninvasive blood component analysis and its advances, Applied Spectroscopy Reviews, 2018,DOI: 10.1080/**.2018.**. (SCI 二区,TOP)
41.陈瑞娟,戚昊峰,李炳南,王慧泉*,王金海. 基于栈式自编码器的磁探测电阻抗成像算法研究. 仪器仪表学报, 2019, 40(1):44-51.
Ruijuan Chen, Haofeng Qi, Bingnan Li, Huiquan Wang*, Jinhai Wang. Study on magnetic detection electrical impedance tomography algorithm based on stacked auto-encoder. Chinese Journal of Scientific Instrument, 2019,40(1): 44-51.(EI:20**8)
42.Huiquan Wang,Fang Xia,Zhe Zhao,Xinwei He,Jinhai wang.Optical Parameters of tissue phantom measurement based on DPDW with multi-frequency modulation.( EI会议)
43.赵喆,王慧,王慧泉,何鑫伟,缪竟鸿,王金海.近红外光谱谱线特性对物质浓度分析误差影响的研究.光谱学与光谱分析.2019,39(4):1070-1074.
ZHAO Zhe, WANG Hui, WANG Hui-quan*, HE Xin-wei, MIAO Jing-hong, WANG Jin-hai*. Influence of Spectral Characteristics on the Accuracy of Concentration Quantitatively Analysis by NIR. Spectroscopy and Spectral Analysis, 2019,39(4): 1070-1074.(SCI:013,IF:0.315)
44.Zhe Zhao,Wen Yan,Haoran Yin,Amreen Batool,Huiquan Wang*,Hui Yu.Quantitative detection of turbid media components using textural features extracted from hyperspectral images.MicrochemicalJournal.2019,149:104009.(SCI:051,IF:2.891)
45.The Optimization of the Reconstruction Accuracy for the Anomaly Location Based on SAE Neural Networks.IEEE Access.2019,7(1):116578-116584.(SCI: 006,IF:2.69)
46.WANG Hui-quan,XIA Fang,JIA Wen,Hu Peng-Fei,ZHAO Zhe,ZHENG Bin,WANG Han-jie,ZHENG Yu,WANG Jin-hai*.Indocyanine Green Accurately Track the Photo therapy Based on W18O49@PLGA Nanostructure In Vivo for Visual Treat.Science of Advanced Materials,2019,11(10):1423-1432.(SCI:011,IF:1.6)
47.Huiquan Wang,Fang Xia,Guang Han,Zhe Zhao,Hongli Chen,Jinhai Wang*.Optical Parameters Detection with Multi-frequency Modulation Based on NIR DPDW.Infrared Physics & Technology,2018,94:96-101.(SCI: 021,IF:1.717)
48.Zhe Zhao*,Haoran Yin,Wen Yan,Hui Wang,Huiquan Wang*.Investigation on near－infrared quantitative detection based on heteromorphic sample pool.Infrared Physics Technology.2019,97:444-447.(SCI: 058)
发明专利（10项）：
1. 2009.02.25 磁性药物引导系统. ZL 6.7，李刚，赵喆，王慧泉.
2. 2015.03.20 一种使用多模式连续血压测量装置的自标定方法，ZL 9.0，王慧泉，乌维磊，庞志祥
3. 2015.08.12. 一种多模式连续血压测量装置，ZL 2015 2 016910.3，王慧泉、乌维磊、庞志祥
4. 2013.2.08一种医用腔道内容物目标成分回收器械，4.8，张发明，王慧泉，姚怡昕
5. 2018.8.07，一种用于测量物质光学参数的漫射光子密度波系统，ZL 2017 2 **.0，王慧泉、何鑫伟、缪竟鸿、王金海、赵喆
软件著作权（20项）：
1. 光学参数测量系统，天津工业大学，2015SR256113
2. 光学断层成像软件，天津工业大学，2015SR254949
3. 荧光断层数据重建软件，天津工业大学，2015SR25589
4. 生物体异质体快速检测系统V1.0，天津工业大学，2017SR532846
5. 光学参数测量系统控制软件V1.0，天津工业大学，2017SR532322
获奖情况 SCHOLARSHIP AND AWARDS:
2018年获天津市科学进步二等奖
2018年获中国产学研合作创新（个人）奖
2018年获中国产学研合作项目成果一等奖
2013年获“The New Venture Competition”美中创新创业竞赛第二名(美国)
2012年获中国科技创业计划大赛“海创新秀奖”（Top20/2000）
2011年获天津市“创新奖学金”一等奖
校内外工作经历WORK EXPERIENCE:
2013年美国Baltimore华人专家****联合会创始人之一、主席
2014年-今天津工业大学电子与信息工程学院生物医学工程系主任
2015年-今中国医疗保健国际交流促进会健康保障分会青年理事
2015-2017年江苏省“企业创新岗”特聘专家（科技副总）
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2018年-今中国人民大学卫生技术评估与医药政策研究中心委员
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