吴依璠
职称：讲师
邮箱：wuyifan@tiangong.edu.cn
专业：生物医学工程
研究方向
血管组织工程
血管干细胞生物学
学习经历
2014.09-2019.06 南开大学生物化学与分子生物学专业，理学博士
2017.10-2018.10 伦敦大学国王学院心血管系，联合培养博士
2010.09-2014.06 山东大学生物技术专业，理学学士
工作经历
2019.11-至今 天津工业大学生命科学学院从事教学和科研工作
代表性论文
[1] 吴依璠，智登科，Adam C. Midgley, 赵强，孔德领*，王恺* . 人工血管组织再生的细胞来源. 中国科学：生命科学,2019,49:1100.
[2] Shirin Issa Bhaloo^#,Wu Yifan^#, Alexandra Le Bras, Yu Baoqi, Gu Wenduo, Xie Yao, Deng Jiacheng, Wang Zhihong, Zhang Zhongyi, Kong Deling, Hu Yanhua, Qu Aijuan, Zhao Qiang*, Xu Qingbo*. Binding of Dickkopf-3 to CXCR7 Enhances Vascular Progenitor Cell Migration and Degradable Graft Regeneration. Circulation Research. 2018, 123(4): 451-466.
[3] Zhu Meifeng^#, Wu Yifan^#, Li Wen, Dong Xianhao, Chang Hong, Wang Kai, Wu Pingli, Zhang Jun, Fan Guanwei, Wang Lianyong, Liu Jianfeng, Wang Hongjun*, Kong Deling*. Biodegradable and elastomeric vascular grafts enable vascular remodeling. Biomaterials. 2018, 183: 306-318.
[4] Wu Yifan, Qin Yibo, Wang Zhihong*, Wang Jianing, Zhang Chuangnian, Li Chen, Kong Deling*. The regeneration of macro-porous electrospun poly(ε-caprolactone) vascular graft during long-term in situ implantation. Journal of Biomedical Materials Research Part B. 2017, 106(4), 1618-1627.
[5] Wang Zhihong^#, Wu Yifan^#, Wang Jianing, Zhang Chuangnian, Yan Hongyu, Zhu Meifeng, Wang Kai*, Li Chen, Xu Qingbo, Kong Deling*. The effect of resveratrol on modulation of endothelial cells and macrophages for rapid vascular regeneration from electrospunpoly(ε-caprolactone) scaffolds. ACS Applied Materials & Interfaces. 2017, 9(23):19541-19551.
[6] Wei Yongzhen^#, Wu Yifan^#, Zhao Runxia, Zhang Kaiyue, Adam C. Midgley, Kong Deling, Li Zongjin*, Zhao Qiang*. MSC-derived sEVs enhance patency and inhibit calcification of synthetic vascular grafts by immunomodulation in a rat model of hyperlipidemia. Biomaterials. 2019, 204: 13-24.
[7] Liu Jing^#, Qin Yibo^#, Wu Yifan, Sun Zhiting, Li Binhan, Jing Huimin, Zhang Chuangnian, Li Chen, Leng Xigang, Wang Zhihong*, Kong Deling*. Biomaterials Science. 2019. 7(3): 914-925.
[8] Qin Kang, Wu Yifan, Pan Yiwa, Wang Kai*, Kong Deling, Zhao Qiang*. Journal of Visualized Experiments. 2018, 136.
[9] Wang Juan^#, Liu Lumei^#, Wu Yifan,Manfred F Maitz, Wang Zhihong, Youngmi Koo, Ansha Zhao, Jagannathan Sankar, Kong Deling, Huang Nan*, Yeoheung Yun*. Acta biomaterialia. 2017, 50: 546-555.
[10] Wang Zhihong^#, Zheng Wenting^#, Wu Yifan, Wang Jianing, Zhang Xiuyuan, Wang Kai, Zhao Qiang, Kong Deling, Ke Tingyu, Li Chen. Biomaterials Science. 2016, 4: 1485-1492.
授权发明专利
2020.1.31可控释放白藜芦醇和/或白藜芦醇衍生物的载体及其制备方法与应用. ZL 2016 1 **.9，王志红，孔德领，吴依璠
代表性科研项目
参与国家自然科学基金重点项目，**，“生物活性小口径人工血管的构建及诱导血管再生机制研究”，2016/1-2020/1，274万，在研。
参加国家自然科学基金面上项目，**，“巨噬细胞在人工血管组织再生中的作用机制研究“，2018.1-2022.1，60万，在研。