一、基本情况
姓名 | 性别 | 出生年月 |
招生专业 |
| ||
刘强 | 男 | 1979/10/12 | ||||
专业技术职务 |
行政职务 | |||||
教授 |
无 |
神经病学 | ||||
招生类型 |
所在单位 | |||||
科学学位(博)\科学学位(硕) | 天津医科大学总医 院 | |||||
最后学历及学位 | ||||||
毕业院校 | 毕业时间 | 所学专业 | 所获学位 | |||
Arizona State University | 2011/05 | 神经科学 | 博士 | |||
| 科学研究主要方向 | |||||
qliu.asu@gmail.com | 中枢神经系统免疫和炎性疾病的机制和治疗 | |||||
二、目前承担科研课题情况
项目名称(级别最高 3-5 项) | 项目来源 | 本人排名 | 本人可支配 经费(万) | 项目起止时间 |
1.白细胞介素 15 在缺血性脑损伤中 的作用及机制 | 国家自然科学基金面上项目 |
1 |
75 | 2015/01- 2018/12 |
2.脑卒中诱导免疫抑制的神经免疫信 号通路 | 天津市应用基础与前沿技术研 究计划 |
1 |
10 | 2015/01- 2017/12 |
3.天津市青年千人 | 天津市 |
1 | 50 万 | 2013/01- 2016/12 |
三、发表论文论著情况
题目 | 刊物或出版社 | 本人排名 | 发表时间 | 收录情况 (SCI、EI) |
1. Non-invasive tracking of CD4+ T cells with a paramagnetic and fluorescent nanoparticle in brain ischemia. |
J Cereb Blood Flow Metab. |
通讯 |
2015, In press. |
SCI |
2. Immune interventions in stroke. |
Nat Rev Neurol. |
2 | 2015, In press. |
SCI |
3. Combination of an immune modulator fingolimod with alteplase in acute ischemic stroke. | Circulation. | 9 | 2015, In press. | SCI |
4. A novel nicotinic mechanism underlies β-amyloid-induced neurotoxicity. | Neuropharmacology. | 通讯 | 2015, May 7. | SCI |
5. Roles of nAChR subunit cytoplasmic loops in acute desensitization. | Neuroscience | 通讯 | 2015;28:3 15-23. | SCI |
6. Ischemic neurons recruit natural killer cells that accelerate brain infarction. | Proc Natl Acad Sci U S A. | 共同 1 | 2014; 111: 2704-9. | SCI |
7. Impact of an immune modulator fingolimod on acute ischemic stroke. | Proc Natl Acad Sci U S A. | 9 | 2014;111: 18315-20. | SCI |
8. Genetic deficiency of β2-nAChRs attenuates brain injury in ischemic stroke. | Neuroscience | 通讯 | 2014;256: 170-7. | SCI |
9. Interleukin-17 inhibits adult hippocampal neurogenesis. | Sci Rep. | 1 | 2014;; 4:7554. | SCI |
10. CX3CR1 Deficiency Suppresses Activation and Neurotoxicity of Microglia/Macrophage in Experimental Ischemic Stroke. | J Neuroinflammation. | 3 | 2014;11:2 6. | SCI |
11. Interleukin-10 producing-B cells and their association with responsiveness to rituximab in myasthenia gravis. | Muscle Nerve. | 4 | 2014;49:4 87. | SCI |
12. Visualization of inflammation and demyelination in 2D2 transgenic mice with rodent MRI. | J Neuroimmunol | 4 | 2013;264: 35-40. | SCI |
13. Responsiveness to reduced dosage of rituximab in Chinese patients with neuromyelitis optica. | Neurology. | 9 | 2013;81:7 10. | SCI |
14. Insights into Distinct Modulation of α7 and α7β2 Nicotinic Acetylcholine Receptors by the Volatile Anesthetic Isoflurane. | J Biol Chem. | 2 | 2013;288: 35793. | SCI |
15. A novel nicotinic mechanism underlies β-amyloid-induced neuronal hyperexcitation. | J Neurosci | 1 | 2013;33:7 253-63. | SCI |
16. Human α4β2 nicotinic acetylcholine receptor as a novel target of oligomeric α-synuclein | Plos One | 1 | 2013;8(2): e55886 | SCI |
17. Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons | FASEB J | 并列 1 | 2012;26:3 34. | SCI |
18. Functional α7β2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of Aβ peptides. | BMC Neuroscience | 1 | 2012;13:1 55. | SCI |
19. Label-free measuring and mapping of binding kinetics of membrane proteins in single living cells. | Nat Chem. | 6 | 2012;4:84 6-53. | SCI |
20. α7β2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their α7-α7 interfaces. | Mol Pharmacol. | 7 | 2012;81:1 75. | SCI |
四、主要业绩