姓名

性别

出生年月

招生专业

闫亚平

男

198004

专业技术职务

行政职务

研究员

无

神经病学

招生类型

所在单位

科学学位（博）\科学学位（硕）

天津医科大学总医

院

最后学历及学位

毕业院校

毕业时间

所学专业

所获学位

陕西师范大学

200806

生物技术

博士

E-mail

科学研究主要方向

qliu.asu@gmail.com

神经免疫免疫病的辅助诊断、发病机制和治疗

项目名称（级别最高 3-5 项）

项目来源

本人排名

本人可支配

经费（万）

项目起止时间

1．少突胶质前体细胞特异性 miR-124 在中 枢神经系统炎性脱髓鞘疾病中的作用机制研 究

国家自然科学基金面上项目

1

70

2014/01-

2017/12

2．干细胞分化产生的免疫原性及免疫耐受 诱导

国家重大基础研究计划（973） 项目

骨干

58

2013/01-

2017/12

3．天津市青年千人

天津市

1

50 万

2013/10-

2016/10

题目

刊物或出版社

本人排名

发表时间

收录情况

（SCI、EI）

1. Experimental models of neuromyelitis

optica: current status, challenges and future directions

Neurosci Bull.

通讯

201506

SCI

2. Fingolimod alters inflammatory mediators

and vascular permeability in intracerebral hemorrhage

Neurosci Bull.

通讯

201505

SCI

3. Silencing IFN-γ binding/signaling in astrocytes versus microglia leads to opposite effects on central nervous

system autoimmunity.

J Immunol.

并列 1

201505

SCI

4. Impact of an immune modulator

fingolimod on acute ischemic stroke.

Proc Natl Acad Sci U S A.

4

2014;111:

18315-20.

SCI

5. Association of circulating follicular helper T

cells with disease course of NMO spectrum disorders

Journal of Neuroimmunology

通讯

2015;278:

239-46

SCI

6. Alterations of natural killer cells in traumatic brain injury.

Neurosci Bull.

7

2014;

30(6):

903-912.

SCI

7. Fingolimod for the treatment of intracerebral

hemorrhage: a 2-arm proof-of-concept study.

JAMA Neurol.

7

2014;71(9

):1092-11

01

SCI

8. Glatiramer acetate ameliorates experimental

autoimmune neuritis.

Immunol Cell Biol

3

2014;92(2

):164-9.

SCI

9. Neurotrophin 3 transduction augments remyelinating and immunomodulatory

capacity of neural stem cells.

Molecular therapy.

并列 1

2014;22(2

):440-50.

SCI

10. Pathway engineering for phenolic acid accumulations in Salvia miltiorrhiza by

combinational genetic manipulation

Metab Eng

2

2014;21:7

1-80

SCI

11. Intronasal delivery of neural stem cells: a CNS-specific, non-invasive cell-based therapy for experimental autoimmune encephalomyelitis.

J Clin Cell Immunol.

3

2013;4(3):

doi:10.41 72/2155-9

899.1000

142

SCI

12. Neuroprotective effect of arctigenin via upregulation of p-CREB in mouse primary neurons and human SH-SY5Y

neuroblastoma cells.

Int J Mol Sci.

11

2013;14(9

):18657-6

9

SCI

13. Anti-MS4a4b treatment abrogates

MS4a4b-mediated protection in T cells and ameliorates experimental autoimmune encephalomyelitis.

Apoptosis

1

2013;18(9

):1106-19.

SCI

14. miR-146b-5p inhibits glioma migration and

invasion by targeting MMP16.

Cancer Letters.

8

2013;24(1

2):637-45.

SCI

15. Tumor-suppressive effects of miR-29c on

gliomas.

Neuroreport.

6

2013;288:

35793.

SCI

16. Inhibitory effects of IL-17 on neural stem cell

proliferation and neural cell differentiation.

BMC Immunol

5

2013;14:2

0.

SCI

17. Effects of Salvianolic acid B on survival,

self-renewal and neuronal differentiation of bone marrow derived neural stem cells

Eur J Pharmacol

11

2012;697(

1-3):32-9

SCI

18. IL-10 deficiency blocks the ability of LPS to

regulate expression of tolerance-related molecules on dendritic cells

Eur J Immonol

4

2012;42(6

):1449-58.

SCI

19. TCR stimulation upregulates MS4a4b expression through induction of AP-1

transcription factor during T cell activation.

Molecular Immunology

1

2012;52(2

):71-8.

SCI

20. Accelerated and enhanced effects of

CCR5-transduced bone marrow neural stem cells on autoimmune encephalomyelitis.

Acta Neuropathol.

并列 1

2012;124

（4）:491- 503.

SCI

21. Early cerebrovascular inflammation in a trangenic mouse model of Alzheimer’s

disease.

Neurobiol Aging.

3

2012;33(1

2):2942-7.

SCI

22. CNS-specific therapy for ongoing EAE by

silencing IL-17 pathway in astrocytes

Mol Ther

1

2012;20(7

):1338-48

SCI

项目名称

年度

获奖名称

等级

本人排名

中枢神经系统炎性脱髓鞘疾病的免疫学、

诊断和治疗研究

2014

天津市科学技术进步奖

二等奖

3